李礼 博士，男，生于1981年9月。西南大学生命科学学院研究员、博士生导师，“重庆市级人才”。


个人简历：
2000.09-2005.06复旦大学公共卫生学院学士学位
2007.01-2011.05香港科技大学生物化学系博士学位
2011.05-2012.02香港科技大学生物化学系博士后
2012.02-2013.06西南大学生命科学学院****
2013.06-至今西南大学生命科学学院研究员
主持的科研项目：
1）国家自然科学基金面上项目（2项）
2）国家自然科学基金青年项目
3）科技部973计划子课题
4）中央高校基本业务经费重大项目
5）西南大学人才引进启动基金
主要研究方向：
以斑马鱼为模式生物：
1）血液细胞发育的分子调控机制。
2）细菌感染过程中，巨噬细胞和粒细胞的行为、功能和相关的分子机理。
3）组织再生过程中，巨噬细胞和粒细胞的行为、功能和相关的分子机理。
个人荣誉：
1）2015年入选/获聘为“重庆市级人才”。
2）2014年入选重庆市高等学校青年骨干教师资助计划。
3）2012年度香港科技大学理学院最佳毕业论文奖。
代表性SCI学术论文：
1.Zhao F, Shi Y, Huang Y, Zhan Y, Zhou L, Li Y, Wan Y, Li H, Huang H, Ruan H, Luo L,Li L*. (2017) Irf8 regulates the progression of myeloproliferative neoplasm (MPN)-like syndrome via Mertk signaling in zebrafish.Leukemia.10.1038/leu.2017.189.(IF=11.7)
2.Yu T, Guo W, Tian Y, Xu J, Chen J,Li L,Wen Z* (2017) Distinct regulatory networks control the development of macrophages of different origins in zebrafish.Blood129(4):509-519.(IF=13.1)
3.Hou Y, Sheng Z, Mao X, Li C, Chen J, Zhang J, Huang H, Ruan H, Luo L,Li L*. (2016)Systemic inoculation of Escherichia coli causes emergency myelopoiesis in zebrafish larval caudal hematopoietic tissue.Sci Rep.6:36853.(IF=5.2)
4.Jin H, Huang Z, Chi Y, Wu M, Zhou R, Zhao L, Xu J, Zhen F, Lan Y,Li L, Zhang W, Wen Z*, Zhang Y*. (2016) cMyb acts in parallel and cooperatively with Cebp1 to regulate neutrophil maturation in zebrafish.Blood128(3):415-26.(IF=13.1)
5.Liu C, Wu C, Yang Q, Gao J,Li L,Yang D, Luo L*.(2016)Macrophages Mediate the Repair of Brain Vascular Rupture through Direct Physical Adhesion and Mechanical Traction.Immunity. 17;44(5):1162-76.(IF=22.8)
6.Chen J, He J,Li L,Yang D, Luo L*. (2016) Cyp2aa9 regulates haematopoietic stem cell development in zebrafish.Sci Rep.6:26608.(IF=5.2)
7.Jia X, Ma K, Xu T, Gao L, Wu S, Fu C, Zhang W, Wang Z, Liu K, Dong M, Jing C, Ren C, Dong Z, Chen Y, Jin Y, Huang Q, Chang X, Deng M,Li L,Luo L, Zhu J, Dang Y, Chang H, Zon L, Zhou Y, Chen S, Pan W*.(2015)Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction.Cell Res. 25(8):946-962.(IF=12.43)
8.Jiang F, Chen J, Ma X, Huang C, Zhu S, Wang F,Li L,Luo L, Ruan H^*, Huang H^*.(2015)Analysis of mutants from a genetic screening reveals the control of intestine and liver development by many common genes in zebrafish.Biochem Biophys Res Commun. 460(3):838-844.
9.Shi W, Fang Z,Li L, Luo L^*. Using zebrafish as the model organism to understand organ regeneration.(2015)Sci China Life Sci. 58(4): 343-351.
10.Shi Y, Zhang Y, Zhao F, Ruan H, Huang H, Luo L,Li L*. (2014) Acetylcholine serves as a derepressor in Loperamide-induced Opioid-Induced Bowel Dysfunction (OIBD) in zebrafish.Sci Rep.Jul 7; 4:5602.(IF=5.2)
11.Yan B, Han P, Pan L, Lu W, Xiong J, Zhang M, Zhang W,Li L*, Wen Z*.(2014) Il-1 beta and Reactive Oxygen Species Differentially Regulate Neutrophil Directional Migration and Basal Random Motility in a Zebrafish Injury-Induced Inflammation.The Journal of Immunology. 192 (12): 5998-6008.(IF=4.9)(*co-corresponding author)
12.Sun J, Liu W,Li L, Chen J, Wu M, Zhang Y, Leung A, Zhang W^*, Wen Z^*, Liao W^*. Suppression of Pu.1 function results in expanded myelopoiesis in zebrafish.(2013)Leukemia. 27(9):1913-1917.(IF=11.7)
13.Zeng Y, Xu J, Li D,Li L,Wen Z, Qu J^*.(2012)Label-free in vivo flow cytometry in zebrafish using two-photon autofluorescence imaging.Optics Letters. 37(13):2490-2492.
14.Li L, Yan B, Shi Y, Zhang W, Wen Z*. (2012) Live Imaging Reveals Differing Roles of Macrophages and Neutrophils during Zebrafish Tail Fin Regeneration.Journal of Biological Chemistry. 287 (30): 25353-25360(IF=4.5)
15.Jin H,Li L, Xu J, Zhen F, Zhu L, Liu P, Zhang M, Zhang W, Wen Z*. (2012) Runx1 regulates embryonic myeloid fate choice in zebrafish through a negative feedback loop inhibiting Pu.1 expression.Blood. 119 (22)：5239-5249(IF=13.1)
16.Li L, Jin H, Xu J, Shi Y, Wen Z*. (2011) Irf8 regulates macrophage versus neutrophil fate during zebrafish primitive myelopoiesis.Blood. 117(4): 1359-1369(IF=13.1)
17.Zhang Y, Jin H,Li L, Qin X, Wen Z*. (2011) cMyb regulates hematopoietic stem/progenitor cell mobilization during zebrafish hematopoiesis.Blood. 118 (15): 4093-4101.(IF=13.1)
*通讯作者
IF为JCR公布的最新期刊五年影响因子

实验室欢迎有志于从事血液发育及免疫功能研究的学生加入（包括保送生和调剂生）。

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