吴国榕
男，1986.02出生于福建尤溪
Email: gronwu@gmail.com, guorongwu@swu.edu.cn
个人主页(实时简历)：https://guorongwu.github.io/Lab,
ORCID: https://orcid.org/0000-0003-4918-3955
工作经历
2017/07-今，西南大学，副研究员
2014/03-2017/06，西南大学，讲师
2021/09-2024/08，Ghent University，Visiting professor (5%)
教育经历
2011/11-2015/10，Ghent University，统计数据分析专业，理学博士
2010/09-2013/12，电子科技大学，生物医学工程专业，工学博士
2008/09-2010/06，电子科技大学，应用数学专业，转为硕博连读
2004/09-2008/06，福建师范大学，数学与应用数学专业，理学学士
研究兴趣及方向
发展基于神经影像数据的动态脑功能活动和脑连接分析算法，开发相应的集成工具包，与统计分析方法相结合应用于心理学和临床疾病研究中。重点关注无创脑刺激(TMS, tDCS)在临床治疗上的脑神经机制（包括抑郁症, 酒精成瘾等）。
科研项目
国家自然科学基金面上项目，无创脑刺激治疗酒精使用障碍的因果调控机制研究，No. **, 2019/01—2022/12，主持，在研。
国家自然科学基金青年项目，时空点过程重构的静息态fMRI动态有向脑连接研究，No. **, 2015/01—2017/12，主持，已结题。
中央高校基本科研业务费学科团队项目，静息态点过程的动态脑连接网络研究， 2014/03—2014/12，主持，已结题。
学术论文（#：共同第一作者；*：通讯作者）
详见 http://scholar.google.com/citations?hl=en&user=BC0dWQsAAAAJ
静息态脑血液动力学响应
Guo-Rong Wu*^#, Nigel Colenbier^#, Sofie Van Den Bossche^#, Kenzo Clauw, Amogh Johri, Madhur Tandon, Daniele Marinazzo. “rsHRF: A Toolbox for Resting-State HRF Estimation and Deconvolution.” Neuroimage, 2021, accepted.
Guo-Rong Wu, Wei Liao, Sebastiano Stramaglia, Ju-Rong Ding, Huafu Chen, Daniele Marinazzo. “A blind deconvolution approach to recover effective connectivity brain networks from resting state fMRI data.” Medical Image Analysis, 2013, 17: 365-374.
(代码下载; 被引次数: 200, Google Scholar 2021-09-18; Impact Factor(2019): 11.148 )
Guo-Rong Wu, Carol Di Perri, Vanessa Charland-Verville, Charlotte Martial, Manon Carriere, Audrey Vanhaudenhuyse, Steven Laureys, Daniele Marinazzo. “Modulation of the spontaneous hemodynamic response function across levels of consciousness.” Neuroimage, 2019, 200: 450–459.
Guo-Rong Wu*, Daniele Marinazzo. “Sensitivity of the resting state haemodynamic response function estimation to autonomic nervous system fluctuations.” Philosophical Transactions of the Royal Society A, 2016, 374: **.
Guo-Rong Wu, Daniele Marinazzo. “Point-process deconvolution of fMRI BOLD signal reveals effective connectivity alterations in chronic pain patients.” Brain Topography, 2014, 28(4): 541-547.
无创脑刺激的神经机制
Guo-Rong Wu^#*, Xiaowan Wang^#, Chris Baeken. “Baseline functional connectivity may predict placebo responses to accelerated rTMS treatment in major depression.” Human Brain Mapping, 2020, 41(3): 632-639.
Guo-Rong Wu, Chris Baeken, Peter Van Schuerbeek, Johan De Mey, Minghua Bi, Sarah C. Herremans. “Accelerated repetitive transcranial magnetic stimulation does not influence grey matter volumes in regions related to alcohol relapse: an open-label exploratory study.” Drug and Alcohol Dependence, 2018, 191: 210-214.
Chris Baeken^#, GuoRong Wu^#*, Harold A Sackeim. “Accelerated iTBS treatment applied to the left DLPFC in depressed patients results in a rapid volume increase in the left hippocampal dentate gyrus, not driven by brain perfusion.” Brain Stimulation, 2020, 13(5): 1211-1217.
Chris Baeken, Jonathan Remue, Marie-Anne Vanderhasselt, Andre R Brunoni, Sara De Witte, Romain Duprat, Ernst HW Koster, Rudi De Raedt,Guo-Rong Wu. “Increased left prefrontal brain perfusion after MRI compatible tDCS attenuates momentary ruminative self-referential thoughts.” Brain Stimulation, 2017, 10(6): 1088-1095.
Anja Flamez^#, Guo-Rong Wu^#*, Wietse Wiels, Peter Van Schuerbeek, Johan De Mey, Jacques De Keyser and Chris Baeken. “Opposite effects of one session of 1 Hz rTMS on functional connectivity depending on the dyskinesia state in Parkinson’s disease.” Clinical Neurophysiology, 2021, 132(4), 851-856.
动态有向脑连接分析
Guorong Wu, Xujun Duan, Wei Liao, Qing Gao, and Huafu Chen. “Kernel canonical-correlation Granger causality for multiple time series.” Physical Review E, 2011, 83: 041921.
Guo-Rong Wu, Fuyong Chen, Dezhi Kang, Daniele Marinazzo, Huafu Chen. “Multi-scale causal connectivity analysis by canonical correlation: theory and application to epileptic brain.” IEEE Trans Biomed Eng, 2011, 58(11): 3088 - 3096.
Guo-Rong Wu, Sebastiano Stramaglia, Huafu Chen, Wei Liao, Daniele Marinazzo. “Mapping the voxel-wise effective connectome in resting state fMRI.”PLoS ONE, 2013, 8(9): e73670.
Guo-Rong Wu, Wei Liao, Sebastiano Stramaglia, Huafu Chen, Daniele Marinazzo. “Recovering directed networks in neuroimaging datasets using partially conditioned Granger causality.” Brain Connectivity, 2013, 3(3): 294-301.
Wei Liao^#*, Guo-Rong Wu^#*, Qiang Xu^#, Gong-Jun Ji, Zhiqiang Zhang, Yu-Feng Zang, Guangming Lu. “DynamicBC: A MATLAB Toolbox for Dynamic Brain Connectome Analysis.” Brain Connectivity, 2014, 4(10):780-90.
(代码下载; 被引次数: 109, Google Scholar 2021-09-18; Impact Factor(2019): 5.263)
人格气质、抑郁症
Guo-Rong Wu*, Chris Baeken. “Brainstem glucose metabolism predicts reward dependence scores in treatment-resistant major depression.” Psychological Medicine, 2021, https://doi.org/10.1017/s5425
Luqing Wei^#, Nana Guo^#, Chris Baeken, Minghua Bi, Xiaowan Wang, Jiang Qiu, Guo-Rong Wu*. “Grey matter volumes in the executive attention system predict individual differences in effortful control in young adults.” Brain Topography, 2019, 32(1): 111-117.
郭娜娜, 吴国榕*, 毕明华, 邱江. “努力控制及其神经基础.” 心理科学，2018, 41(3): 546-552.
Chris Baeken^#, Guo-Rong Wu^#*, Roland Rogiers, Jonathan Remue, Gilbert Md Lemmens, Rudi De Raedt. “Cognitive Behavioral based Group Psychotherapy focusing on Repetitive Negative Thinking: decreased uncontrollability of rumination is related to brain perfusion increases in the left dorsolateral prefrontal cortex.” Journal of Psychiatric Research, 2021, 136, 281-287.
Guo-Rong Wu, Rudi De Raedt, Peter Van Schuerbeek, Chris Baeken. “Opposite subgenual Cingulate Cortical functional connectivity and metabolic activity patterns in refractory melancholic Major Depression.” Brain Imaging and Behavior, 2020, 14(2): 426–435.
Chris Baeken, Yanfeng Xu, Robrecht Dockx, Guo-Rong Wu*, Kathelijne Peremans, Jimmy. H. Saunders, Chris Vanhove, Philip De Vos, Rudi De Raedt. “Hostility in medication resistant Major Depression and comorbid Generalized Anxiety Disorder is related to increased hippocampal-amygdala 5-HT_2A receptor density.” European Archives of Psychiatry and Clinical Neuroscience, 2021, 271, 1369–1378.
Guo-Rong Wu, Chris Baeken. “Longer depressive episode duration negatively influences HF-rTMS treatment response: a cerebellar metabolic deficiency?”Brain Imaging and Behavior, 2017, 11(1): 8-16.
心脑交互
Luqing Wei, Guo-Rong Wu*. “Structural Covariance of the Salience Network Associated with Heart Rate Variability.” Brain Imaging and Behavior, 2021, 15 (2), 896-905.
Luqing Wei, Hong Chen, Guo-Rong Wu*. “Heart rate variability associated with grey matter volumes in striatal and limbic structures of the central autonomic network.” Brain Research, 2018, 1681: 14–20.
Luqing Wei, Hong Chen, Guo-Rong Wu*. “Structural Covariance of the Prefrontal-Amygdala Pathways Associated with Heart Rate Variability.” Frontiers in Human Neuroscience, 2018, 12.
其他
Luqing Wei^#, Guo-Rong Wu^#*, Minghua Bi, Chris Baeken. “Effective Connectivity Predicts Cognitive Empathy in Cocaine Addiction: A Spectral Dynamic Causal Modeling Study.” Brain Imaging and Behavior, 2021, 15 (3), 1553-1561.
Xiaowan Wang, Chris Baeken, Mengxia Fang, Jiang Qiu, Hong Chen, Guo-Rong Wu*. “Predicting trait-like individual differences in fear of pain in the healthy state using gray matter volume.” Brain Imaging and Behavior, 2019, 13(5): 1468–1473.
Sam Luc Bart Bonduelle*, Qinyuan Chen, Guo-Rong Wu*, Caroline Braet, Rudi De Raedt, Chris Baeken. "Exposure to criticism modulates left but not right amygdala functional connectivity in healthy adolescents: individual influences of perceived and self-criticism." Front. Psychiatry, 2021, 12, 1097.
王潇, 吴国榕*, 吴欣然, 邱江, 陈红. “语言功能偏侧化及其与利手、功能连接的关系.” 心理科学进展, 2020, 28(5): 778-789.
马丽伟, 吴国榕*, 魏鲁庆. “脑白质功能-来自BOLD-fMRI的证据.” 生物化学与生物物理进展, 2021, 已录用.
软件开发
rsHRF (静息态血液动力学响应函数估计、去卷积，及脑连接分析工具包，包含Matlab、 Python和Docker版本，详见https://www.nitrc.org/projects/rshrf; Matlab版本支持脑连接分析和HRF可视化，实例分析见https://github.com/compneuro-da/rsHRF/ )
DynamicBC ( http://restfmri.net/forum/DynamicBC )
Brain GPS (计算机软件著作权No.**) 基于MRI信息的靶区定位
Rat-fMRI 大鼠的结构和功能fMRI数据处理软件
讲授课程
心理统计学(课程主页：https://psystat.github.io/ ), 高等数学
脑连接组学