季平
学术学位博士生导师

教授





口腔医学院





学科信息


个人简介
二级教授、医学博士、博士生导师，留美****。现任重庆医科大学附属口腔医院院长，“重庆市英才计划创新领军人才”。中华口腔医学会颌面外科专业委员会常务委员、种植专业委员会常务委员、口腔颌面-头颈肿瘤专业委员会常务委员、口腔医学教育专业委员会常务委员、口腔医疗服务分会常务委员；中国医师协会口腔医师分会常务委员；重庆市口腔医学会会长。从事口腔颌面外科临床工作二十余年，主要技术专长为口腔颌面外科、头颈部血管瘤治疗、头颈部肿瘤序列治疗、头颈部组织器官形态及功能重建、头颈部复合创伤救治。参与全国统编教材编写，参编及主编著作10余部。获省部级及国家级科研项目10余项，其中主研国家自然科学基金3项，获省部级及厅局级科技成果奖3项。发表论文近百篇，其中SCI论文30余篇。






成果奖励
1. 季平(1/10), 口腔癌精准诊疗和个性化修复重建的基础与临床应用研究, 重庆市人民政府, 科技进步, 省部二等奖, 2016 （季平; 廖贵清; 李勇; 邱丽华; 赵洪伟; 王涛; 张富贵; 庞谅; 刘文钊; 朱露颖）
2. 季平(1/9), 口腔鳞癌早期筛查及个性化综合防治的临床和基础研究, 重庆市卫生 和计划生育委员会, 医学科技成果奖, 其他, 2014, （季平; 杨凯; 李勇; 邱丽华; 王涛; 张富贵; 庞谅; 李颖; 肖水生）
3. 季平(2/7), 基于树突状细胞的人舌鳞癌免疫治疗的基础研究, 重庆市卫生局, 医 学科技成果奖, 其他, 2012, （李勇; 季平; 郁葱; 骆德平; 李代庆; 王启明; 童熹）



科研项目
1. 国家自然科学基金委员会，面上项目，**，YAP/TAZ复合体在下颌骨发育中 的功能及作用机制，2019-01至2022-12，59万元，在研，主持。
2. 重庆市科委项目，全口数字化口腔种植修复技术的推广，2019-02至2020-02，30万 元，在研，主持。
3. 国家自然科学基金委员会，青年项目，**，血糖响应型、自律性靶向释药种植体改善2型糖尿病大鼠骨结合的研究，2018-01至2020-12，20万元，在研，参与。
4. 重庆市科委社会民生科技创新专项子课题，SDF-1与TATp修饰的包裹放射性核素131 I新型超声微泡靶向口腔癌及颈部淋巴转移的精准放疗的实验研究---疾病精准放疗技术研 发及应用，2016-10至2019-10，30万元，结题，主持。
5. 重庆市科委项目，cstc2015shmszx10008，多孔钽材料新型牙种植体的应用开发研 究，2016-01至2018-12，20万元，结题，主持。
6. 重庆市渝北区科委项目，2015（社）01号，多孔钽材料新型牙种植体的应用开发研 究，2015-12至2018-12，25万元，结题，主持。
7. 国家自然科学基金委员会，青年项目，**，SDF-1/CXCR4生物轴对钙敏感受体介导的大鼠游离皮瓣缺血/再灌注损伤通路的拮抗作用及机制的研究，2015-01至2017-12，23万元，结题，参与。



论文情况
1. Dize Li, Kaiwen Chen, Lian Duan, Tiwei Fu, Jiao Li, Zhixiang Mu, Si Wang, Qin Zou, Li Chen, Yangyingfan Feng, Yihan Li, Hongmei Zhang, Huanan Wang, Tao Chen, Ping Ji*. Strontium Ranelate Incorporated Enzyme-Cross-Linked Gelatin Nanoparticle/Silk Fibroin Aerogel for Osteogenesis in OVX-Induced Osteoporosis. ACS Biomaterials Science & Engineering, 2019,5:1440-1451.
2. Li D, Li Y, Shrestha A, Wang S, Wu Q, Li L, Guan C, Wang C, Fu T, Liu W, Huang Y, Ji P*, Chen T. Effects of Programmed Local Delivery from a Micro/Nano-Hierarchical Surface on Titanium Implant on Infection Clearance and Osteogenic Induction in an Infected Bone Defect. Adv Healthc Mater, 2019, 8(11):e**.
3. Luo P, Feng C, Jiang C, Ren X, Gou L, Ji P*, Xu J. IL-37b alleviates inflammation in the temporomandibular joint cartilage via IL-1R8 pathway. Cell Prolif. 2019, 52(6):e12692.
4. Xu Y, Xia M, Chen T, Yang Y, Fu G, Ji P*, Wu Q. Inferior alveolar nerve transection disturbs innate immune responses and bone healing after tooth extraction. Ann N Y Acad Sci, 2019, 1448(1):52-64.
5. Gao H, Li X, Wang C, Ji P*, Wang C. Mechanobiologically optimization of a 3D titanium-mesh implant for mandibular large defect: A simulated study. Mater Sci Eng C Mater Biol Appl, 2019, 104:109934.
6. Huang H, Wang J, Zhang Y, Zhu G, Li YP, Ping J*, Chen W. Bone resorption deficiency affects tooth root development in RANKL mutant mice due to attenuated IGF-1 signaling in radicular odontoblasts. Bone, 2018, 114:161-171.
7. Wang H, Su K, Su L, Liang P, Ji P*, Wang C. The effect of 3D-printed Ti6Al4V scaffolds with various macropore structures on osteointegration and osteogenesis: A biomechanical evaluation. J Mech Behav Biomed Mater, 2018, 88:488-496.
8. He S, Wei S, Wang J, Ji P*. Chronic periodontitis and oral health-related quality of life in Chinese adults: A population-based, cross-sectional study. J Periodontol, 2018, 89(3):275-284.
9. He SL, Wang JH, Ji P*. Validation of the Pain Resilience Scale in Chinese-speaking patients with temporomandibular disorders pain. J Oral Rehabil, 2018,45(3):191-197.
10. Zhang C, Qin D, Shen L, Ji P*, Wang J. Does audiovisual distraction reduce dental anxiety in children under local anesthesia? A systematic review and meta-analysis.Oral Dis, 2019, 25(2):416-424.
11. Liu WZ, Su LY, Xie XD, Xiang XR, Huang J, Ji P*. Prevalence and Years Lived with Disability for Dental Caries among Children Aged 0-14 Years in China, 1990-2016. Biomed Environ Sci, 2018, 31(5):376-381.
12. Wang M, Shi G, Bian C, Nisar MF, Guo Y, Wu Y, Li W, Huang X, Jiang X, Bartsch JW, Ji P*, Zhong JL. UVA Irradiation Enhances Brusatol-Mediated Inhibition of Melanoma Growth by Downregulation of the Nrf2-Mediated Antioxidant Response. Oxid Med Cell Longev, 2018:**.
13. Song L, Gao LN, Wang J, Thapa S, Li Y, Zhong XB, Zhao HW, Xiang XR, Zhang FG, Ji P*. Stromal Cell-Derived Factor-1α Alleviates Calcium-Sensing Receptor Activation-Mediated Ischemia/Reperfusion Injury by Inhibiting Caspase-3/Caspase-9-Induced Cell Apoptosis in Rat Free Flaps. Biomed Res Int, 2018:**.
14. Bai S, Mu Z, Huang Y, Ji P*. Guanylate Binding Protein 1 Inhibits Osteogenic Differentiation of Human Mesenchymal Stromal Cells Derived from Bone Marrow. Sci Rep, 2018,8(1):1048.
15. Qiu Y, Li C, Wang Q, Zeng X, Ji P*. Tanshinone IIA induces cell death via Beclin-1-dependent autophagy in oral squamous cell carcinoma SCC-9 cell line. Cancer Med, 2018,7(2):397-407.
16. Tan Y, Yan B, Xue L, Li Y, Luo X, Ji P*. Surface-enhanced Raman spectroscopy of blood serum based on gold nanoparticles for the diagnosis of the oral squamous cell carcinoma. Lipids Health Dis, 2017,16(1):73.
17. He S, Wang J, Wei S, Ji P*. Development and validation of a condition-specific measure for chronic periodontitis: Oral health impact profile for chronic periodontitis. J Clin Periodontol, 2017,44(6):591-600.
18. Dou L, Wu Y, Yan Q, Wang J, Zhang Y, Ji P*. Secretome profiles of immortalized dental follicle cells using iTRAQ-based proteomic analysis. Sci Rep, 2017, 7(1):7300.
19. Wang J, Li L, Gao L, Guan C, Su K, Li L, Luo W, Chen H, Ji P*. Identification of differentially expressed genes in oral squamous cell carcinoma TCA8113 cells. Oncol Lett, 2017, 14(6):7055-7068.
20. Zhang F, Li Y, Zhang H, Huang E, Gao L, Luo W, Wei Q, Fan J, Song D, Liao J, Zou Y, Liu F, Liu J, Huang J, Guo D, Ma C, Hu X, Li L, Qu X, Chen L, Yu X, Zhang Z, Wu T, Luu HH, Haydon RC, Song J, He TC, Ji P*. Anthelmintic mebendazole enhances cisplatin's effect on suppressing cell proliferation and promotes differentiation of head and neck squamous cell carcinoma (HNSCC). Oncotarget, 2017, 8(8):12968-12982.
21. Wang Q, Cao L, Liu Y, Zheng A, Wu J, Jiang X, Ji P*. Evaluation of synergistic osteogenesis between icariin and BMP2 through a micro/meso hierarchical
porous delivery system.Int J Nanomedicine, 2017,12:7721-7735.
22. Jin X, Xu H, Wu X, Li T, Li J, Zhou Y, Dan H, Jiang L, Zeng X, Ji P*, Chen Q. KDM4A as a prognostic marker of oral squamous cell carcinoma: Evidence from tissue microarray studies in a multicenter cohort. Oncotarget, 2017, 8(46):80348-80357.
23. Gao X, Song J, Zhang Y, Xu X, Zhang S, Ji P*, Wei S. Bioinspired Design of Polycaprolactone Composite Nanofibers as Artificial Bone Extracellular Matrix for Bone Regeneration Application. ACS Appl Mater Interfaces, 2016, 8(41):27594-27610.
24. Li W, Zhu Y, Singh P, Ajmera DH, Song J, Ji P*. Association of Common Variants in MMPs with Periodontitis Risk. Dis Markers, 2016:**.
25. Wang C, Zhang W, Ajmera DH, Zhang Y, Fan Y, Ji P*. Simulated bone remodeling around tilted dental implants in the anterior maxilla. Biomech Model Mechanobiol, 2016, 15(3):701-12.
26. Zhang F, Song J, Zhang H, Huang E, Song D, Tollemar V, Wang J, Wang J, Mohammed M, Wei Q, Fan J, Liao J, Zou Y, Liu F, Hu X, Qu X, Chen L, Yu X, Luu HH, Lee MJ, He TC, Ji P*. Wnt and BMP Signaling Crosstalk in Regulating Dental Stem Cells: Implications in Dental Tissue Engineering. Genes Dis, 2016, 3(4):263-276.
27. Li B, He M, Li W, Luo Z, Guo Y, Li Y, Zang C, Wang B, Li F, Li S, Ji P*. Dissolution and pharmacokinetics of baicalin-polyvinylpyrrolidone coprecipitate. J Pharm Pharmacol, 2013, 65(11):1670-8.
28. Zou B, Sun S, Qi X, Ji P*. Aldehyde dehydrogenase activity is a cancer stem cell marker of tongue squamous cell carcinoma. Mol Med Rep, 2012, 5(4):1116-20.



知识产权
1. 季平，郁葱，林必盛。口腔外科用异形管喉罩，2016-10-12，中国 ZL 2016 2. **.0（专利）





研究方向
尚未录入;