职位：副教授，硕士生导师联系邮箱：yangjichun@cqu.edu.cn




学习经历
2015/09-2018/06 南开大学 博士
2012/09-2015/06 辽宁大学 硕士
2008/09-2012/06 辽宁大学 学士


工作经历

2021/01-至今， 重庆大学医学院， 副教授
2018/07-2020/07， 清华大学化学系高分子化学与物理研究所， 博士后研究员


研究方向
1、以有机、无机、高分子纳米材料为研究载体，致力于纳米诊疗一体化平台构建方面的研究工作，针对于临床上肿瘤治疗所面临的毒副作用大、易产生耐药、治疗后易转移与复发等瓶颈问题，设计具有肿瘤成像引导能力的靶向纳米药物递送体系，从而实现癌症的可视化精准治疗。
2、结合纳米材料技术，实现肿瘤标志物的快速灵敏检测。



教学课程
1、分子医学前沿
2、医学学术规范与研究生论文写作指导


代表性论文
[1] Yang J C, Pan S J, Gao S Q, Li T Y, Xu H P, CO/chemosensitization/ antiangiogenesis synergistic therapy with H₂O₂-responsive diselenide-containing polymer, Biomaterials, 2021, 271, 120721.
[2] Yang J C, Pan S J, Gao S Q, Dai Y H, Xu H P, Anti-recurrence/metastasis and chemosensitization therapy with thioredoxin reductase-interfering drug delivery system, Biomaterials, 2020, 249, 120054.
[3] Yang J C, Shang Y, Li Y H, Cui Y, Yin X B, An “all-in-one” antitumor and anti-recurrence/metastasis nanomedicine with multi-drug co-loading and burst drug release for multi-modality therapy, Chemical Science, 2018, 9, 7210-7217.
[4] Yang J C, Chen Y, Li Y H, Yin X B, Magnetic resonance imaging-guided multi-drug chemotherapy and photothermal synergistic therapy with pH and NIR-stimulation release, ACS Appl. Mater. Interface, 2017, 9, 22278-22288.
[5] Yang J C, Yin X B, CoFe₂O₄@MIL-100(Fe) hybrid magnetic nanoparticles exhibit fast and selective adsorption of arsenic with high adsorption capacity, Scientific Reports, 2017, 7, 40955.
[6] Yang J C, Dong Y Y, Wang L L, Zhang D F, Zhang Z Z, Zhang L, Highly sensitive detection of faropenem using amino functionalizedcarbon nanotube modified electrode with ionic liquid as binder:Insight into the interaction of faropenem with human serum albumin. Sensors and Actuators B: Chemical, 2015, 211, 59-66.
[7] Yang J C, Wang Q, Zhang M H, Zhang S M, Zhang L, An electrochemical fungicide pyrimethanil sensor based on carbon nanotubes/ionic-liquid construction modified electrode. Food Chemistry, 2015, 187, 1-6.
[8] Yang J C, Wang X, Zhang D F, Wang L L, Li Q, Zhang L, Simultaneous determination of endocrine disrupting compounds bisphenol F and bisphenol AF using carboxyl functionalized multi-walled carbon nanotubes modified electrode. Talanta, 2014, 130, 207-212.
[9] Yang J C, Zhang D F, Wang L L, Long N, Zhang M H, Zhang L, An electrochemical method for high sensitive detection of thiabendazole and its interaction with human serum albumin. Food Analytical Methods, 2015, 8, 507-514.
[10] Pan S J, Yang J C, Ji S B, Li T Y, Gao S Q, Sun C X, Xu H P, Cancer therapy by targeting thioredoxin reductase based on selenium-containing dynamic covalent bond, CCS Chemistry, 2020, 2, 225-235.
[11] Yin, H Q, Yang J C, Yin X B, Ratiometric fluorescence sensing and real-time detection of water in organic solvents with one-pot synthesis of Ru@MIL-101(Al)-NH₂. Analytical Chemistry, 2017, 89, 13434-13440.
[12] Wang X, Yang J C, Wang Y J, Li Y H, Wang F, Zhang L, Studies on electrochemical oxidation of estrogenic disrupting compound bisphenol AF and its interaction with human serum albumin. Journal of Hazardous Materials, 2014, 276, 105-111.
[13] Wang Q, Yang J C, Dong Y Y, Zhang L, One-Step Fabrication of a Multifunctional Magnetic Nickel Ferrite/ Multi-walled Carbon Nanotubes Nanohybrid-Modified Electrode for the Determination of Benomyl in Food. Journal of Agricultural and Food Chemistry, 2015, 63, 4746-4753.
[14] Wang Q, Yang J C, Zhang D F, Zhang L, Ionic liquid @LiFe₅O₈/MWCNTs magnetic nanohybrid as enhanced sensing platform for highly sensitive detection of estrogenic disrupting compound bisphenol AP. Journal of Appllied Electrochemistry, 2016, 46, 963-974.
[15] Dong Y Y, Yang J C, Liu X Y, Zhang L, Ionic liquids-modified CaFe₂O₄/MWCNTs nano-hybrid as an electrode material for detection of carbendazim. Journal of the Electrochemical Society, 2016, 163, 652-658.
[16] Xu T C, Zhang L, Yang J C, Li N, Yang L J, Jiang X Q, Development of electrochemical method for the determination of olaquindox using multi-walled carbon nanotubes modified glassy carbon electrode. Talanta, 2013, 109, 185-190.
[17] Zhang L, Pan F, Liu X Y, Yang L J, Jiang X Q, Yang J C, Shi W, Mulit-walled carbon nantubes as sorbent for recovery of endocrine disrupting compound-bisphenol F from wastewater. Chemical Engineering Journal, 2013, 218, 238-246.
[18] Liu X Y, An S, Zhou X Y, Zhang L, Zhang Y Y, Shi W, Yang J C, Comparative studies of removal of methyl green and basic fuchsin from wastewater by a novel magnetic nanoparticles Mg-ferrites. Journal of Dispersion Science and Technology, 2013, 87, 1553-1559.


专利
杨纪春，尹学博. 一种磁性纳米无机砷吸附剂的制备方法及其应用。中国，CN5.5


科研项目

1.国家自然科学基金青年项目，DNA水凝胶原位固定法用于乳腺癌精准化疗并抗转移与复发的实验研究， 2022-2024，24万元，项目负责人
2.中央高校基本科研业务费医工融合专项，MnO2@EVs用于乳腺癌早期筛查及放化疗增敏新技术研究，2021-2023，30万元，项目负责人
3.中国博士后科学基金，TR响应型含硒高分子用于抗肿瘤转移与复发的靶向化疗，2019-2020，8万元，项目负责人


其他

本课题组师资力量强大，研究方向多元化，主要从事诊疗一体化研究、纳米医学、疾病检测新技术开发、核酸检测等方面研究，课题组氛围极其融洽，导师幽默风趣关心同学身心健康，能够为同学提供多方面及多元化发展，希望同学在身心愉悦的科研环境中培养起自己的科研能力，提升自己的科研思维，热忱欢迎具有医学、材料学、化学、细胞生物学、分子生物学背景的本科生、研究生、博士生及博士后加入本课题组。联系邮箱：yangjichun@cqu.edu.cn。







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