教授、主任医师、科主任


学习经历
1999/09–2002/06，重庆医科大学，内科学博士
1996/09–1999/06，重庆医科大学，内科学硕士
1978/09–1983/06，贵阳医学院，内科学学士


工作经历
2016/02–至今，重庆大学附属肿瘤医院，消化内科，教授、主任医师、科主任
2012/12 - 2013/06，香港大学玛丽医院肝脏胃肠科、内视镜中心进修学习
2002/09–2016/01，重庆医科大学附属第二医院消化内科，教授、主任医师、副主任
1987/07–1996/08，重庆市急救医疗中心，消化内科，医师
1983/10–1987/06，遵义市人民医院，内科，医师


研究方向、教学课程
研究方向：
从事胃肠肝胰等疾病诊治与研究30余年，对消化道出血、重型胰腺炎、肝硬化及其并发症、炎症性肠病等的临床诊治有较深入的研究。特别擅长胃肠肝胰等疾病及在内窥镜下的诊断、介入治疗。如对肝硬化及其并发症的临床评估/诊治、EMRL、EMR、ESD、超声内镜的诊断、超声内镜引导下的穿刺活检/注射/引流。
目前临床工作的主要研究结果：（1）结扎术可以有效治疗食管/食管+胃静脉曲张，并将结扎术治疗用于胃静脉曲张的治疗，治疗水平处于国内领先；（2）结扎术治疗静脉曲张的疗效与肝功能、门脉压力、侧枝循环开放等密切相关；（3）静脉曲张经过有效的结扎术治疗可以减少肝硬化的死亡率，也有可能延长患者的生存时间；（4）较高的消化道早癌检出率，胃肠粘膜、粘膜下肿瘤早期治疗通过EMR、EMRL、ESD等内镜下介入治疗手段完成，在本市处于领先水平；（5）脂多糖结合蛋白可能是诊断肝硬化自发性腹膜炎的另一个有效指标；（6）结直肠癌的发病率、发病部位等在川渝地区近年有新的变化；作为重庆市超声内镜的领军者，引领重庆市内医疗单位开展超声内镜的诊疗规范、超声内镜的介入治疗。在国内尤其是西南地区处于领先水平。
教学课程：
黄疸、消化内科、诊断学腹部体检


成果：1.文章2.专利3.项目4.获奖
发表50余篇论文，近三年以第一作者及通讯作者发表SCI 17篇。申报多项专利，其中2项发明专利正在授权中。
文章：
1、Modified endoscopic full-thickness resection of gastric stromal tumor originating from the muscularis propria layer. JCR 2区2020.5
2、The association of hepatitis B virus screening and antiviral prophylaxis with adverse liver outcomes in Chinese cancer patients undergoing chemotherapy A retrospective study. JCR 2区 2020.4
3、Comparative Efficacy of 2L Polyethylene Glycol Alone or With Ascorbic Acid vs. 4L Polyethylene Glycol for Colonoscopy: A Systematic Review and Network Meta-Analysis of 12 Randomized Controlled Trials. JCR 1区2019.8
4、A Randomized Trial of Split Dose 3 L Polyethylene Glycol Lavage Solution, 2 L Polyethylene Glycol Lavage Combined With Castor Oil, and 1 L of Polyethylene Glycol Lavage Solution Combined With Castor Oil and Ascorbic Acid for Preparation for Colonoscopy. JCR 1区 2019.7
5、Low-Volume Polyethylene Glycol Improved Patient Attendance in Bowel Preparation Before Colonoscopy: A Meta-Analysis With Trial Sequential Analysis. JCR 1区2019.5
6、Early enteral nutrition supplemented with probiotics improved the clinical outcomes in severe head injury Some promising findings from Chinese patients. JCR 2区2019.4
7、Prophylaxis With Oral Zinc Sulfate Against Radiation Induced Oral Mucositis in Patients With Head and Neck Cancers: A Systematic Review and Meta-Analysis of Four Randomized Controlled Trials. JCR 2区2019.3
8、Oral Zinc Sulfate for Prevention and Treatment of Chemotherapy-Induced Oral Mucositis: A Meta-Analysis of Five Randomized Controlled Trials. JCR 2区2018.11
9、Prophylaxis with oral zinc sulfate against radiation-induced oropharyngeal mucositis in patients with head and neck cancer Protocol for a meta-analysis of randomized controlled trials. JCR 2区2018.11
10、Efficacy of compound Lactobacillus acidophilus tablets combined with quadruple therapy for Helicobacter pylori eradication and its correlation with pH value in the stomach: a study protocol of a randomised, assessor-blinded, single-centre study. JCR 2区 2018.10
11、Supplemented Use of Pre-, Pro-, and Synbiotics in Severe Acute Pancreatitis: An Updated Systematic Review and Meta-Analysis of 13 Randomized Controlled Trials. JCR 1区2018.6
12、Efficacy and safety of oral zinc sulfate in the prevention of chemotherapy-induced oral mucositis: Protocol for a meta-analysis of randomized controlled trials. JCR 2区2018.5
13、Comparative efficacy of low volume versus traditional standard volume PEG on bowel preparation before colonoscopy: Protocol for an updated meta-analysis with trial sequential analysis. JCR 2区2018.4
14、Comparative efficacy of combination of 1L polyethylene glycol, castor oil and ascorbic acid versus 2L polyethylene glycol plus castor oil versus 3L polyethylene glycol for colon cleansing before colonoscopy: Study protocol of a randomized, double-blind, single-center study. JCR 2区2018.4
15、Effects of polyethylene glycol 2 L alone or with ascorbic acid compared with polyethylene glycol 4 L alone for bowel preparation before colonoscopy: protocol for a systematic review and network meta-analysis. JCR 2区2017.10
16、Antibiotic prophylaxis for infections in patients with acute stroke: a systematic review and meta-analysis of randomized controlled trials. JCR 2区2017.10
17、Concurrent chemo-radiotherapy with S-1 as an alternative therapy for elderly Chinese patients with non-metastatic esophageal squamous cancer: evidence based on a systematic review and meta-analysis. JCR 2区2017.6
项目：
主持、参与完成自然科学国家青年基金、重庆市科委自然基金重点项目、重庆市科委自然基金面上项目、重庆市教委基金、重庆医科大学基金等课题；作为主要研究者承担多项临床试验，在研临床试验项目14项。
近4年主持科研项目：
1、重庆市卫生计生委卫生适宜技术推广项目，常见消化道肿瘤的早期诊断与内镜治疗技术的推广
2、重庆市卫生计生委卫生适宜技术推广项目，内镜下黏膜切除术（EMR）
3、重庆市科委中央引导地方科技发展专项资金，人工智能辅助诊断系统在消化道早期癌诊断中的应用



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