王锐
发布时间：2015/4/28 16:12:54作者：药学系责编：药学与生物工程学院阅读次数：339


 

 

王锐，男，1974 年出生，四川阆中，理学博士， 副教授。 Research on Chemical Intermediates评审专家 ，Letters in Drug Design & Discovery评审专家，Drug Design, Development and Therapy评审专家
学习经历：

 2006/09-2009/06, 中国科学院学，成都生物研究所，药物化学，博士
 2003/09-2006/06，四川大学，化学学院，生物有机化学，硕士

专业方向：
有机合成方法学研究：杂环合成研究、有机小分子催化不对称合成、C-C键形成研究； 抗糖尿病药物及抗高血压药物合成及药物中间体合成研究。

科研成果：

近年来发表SCI 收录学术论文多篇。主持及主研国家自然基金及重庆市科委、教委项目多项。

[1]Rui Wang,* Chun-hong An, Yang Li, Yue Zhao, Tao Wang, Ao Li* Direct Synthesis of 2-Arylbenzothiazoles from Benzothiazoles with Phenylglycine Derivatives Mediated by Cu(OTf)2/K2S2O8 Tetrahedron Letters 2015, 56, 2077-2082. (SCI 2.6)
[2] Ao Li*, Jun Wang, Dan-Ping Zhu, Xiao-Xun Zhang, Ruo-Lin Pan, Rui Wang*. Arctigenin suppresses transforming growth factor-β1-induced expression of monocyte chemoattractant protein-1 and the subsequent epithelial-mesenchymal transition through reactive oxygen species-dependent ERK/NF-κB signaling pathway in renal tubular epithelial cells. Free radical research, 2015, in press, DOI: 10.3109/**.2015.**.(SCI 2.9)
[3] Rui Wang,* Yong-liang Ding, Hong Liu, Shu Peng, Jie Ren, Lei Li Copper-catalyzed multicomponent reactions of 2-iodoanilines, benzylamines, and elemental sulfur toward 2-arylbenzothiazoles Tetrahedron Letters 2014, 55, 945-949. (SCI, 2.6)
[4] Rui Wang,* Hong Liu, Liang Yue, Xiao-ke Zhang, Qiu-yuan Tan, Ruo-lin Pan Transition metal-free direct amination of benzoxazoles using formamides as nitrogen sources Tetrahedron Letters 2014, 55, 2233-2237. (SCI, 2.6, 被引频次 6)
[5] Rui Wang,* Wen-juan Yang, Liang Yue, Wei Pan, Hong-yao Zeng. DDQ-Promoted C–S Bond Formation: Synthesis of 2-Aminobenzothiazole 　 Derivatives under Transition-Metal-, Ligand-, and Base-Free Conditions, Synlett., 2012, 11, 1643.(SCI, 2.7, 被引频次 7，有机化学门户网站评述http://www.organic-chemistry.org;  Eur. J. Org. Chem.综述)
[6] Rui Wang,* Zhi Chen, Liang Yue, Wei Pan, Jun-Jie Zhao. Direct transition metal-free C–S bond formation: synthesis of 2-aminobenzothiazole derivatives via base-mediated approach. Tetrahedron Lett., 2012, 53, 4529. (SCI 2.6, 被引频次 10).
[7] Ji YJ, Shu M, Lin Y,Wang YQ, Wang R, Hu Y , Lin ZH .Combined 3D-QSAR modeling and
molecular docking study on azacycles CCR5 antagonists. Journal of Molecular Structure 1045: 35-41, 2013.(SCI )
[8] Yang WJ , Shu M, Wang YQ , Wang R, Hu Y, Meng, LX ,Lin, ZH.3D-QSAR and docking studies of 3-Pyridine heterocyclic derivatives as potent PI3K/mTOR inhibitors. Journal of Molecular Structure 1054 : 107-116, 2013.(SCI)
[9] Wang R, Huang TK, Shi L,. Li BG. Lu XX. Heteropoly Acids Catalyzed Direct Mannich Reactions: Three-Component Synthesis of N-Protected β-Amino Ketones，Synlett., 2007,  2197–2200. (SCI 2.7, 被引频次7)
[10] Wang R, Li BG, Huang TK, Shi L, Lu XX. NbCl5-Catalyzed One-pot Mannich-type Reaction: Three Component Synthesis of β–Amino Carbonyl Compounds, Tetrahedron Lett., 2007, 48, 2071–2073. (SCI 2.6, 被引频次 105)
[11] Wang R, Lu XX, Yu XQ, Shi L, Sun Y. Acid-Catalyzed Solvent-Free Synthesis of 2-Arylbenzimidazoles under Microwave Irradiation. Journal of Molecular Catalysis. A, Chemical, 2007, 266, 198–201. (SCI 2.8, 被引频次32)


 





 

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