许华平 教授
电话：86-
Email：xuhuaping@mail.tsinghua.edu.cn
教育背景1997.9-2001.7 吉林大学化学学院 高分子材料与工程 工学学士学位
2001.9-2006.7 吉林大学化学学院 高分子化学与物理 理学博士学位
2004.4-2005.3 比利时鲁汶大学 交换博士生 （导师： Wim Dehaen 教授，Mario Smet 教授）
工作履历2006.08 - 2008.07 荷兰屯特大学MESA+纳米技术研究所 　博士后（合作导师:David Reinhoudt教授，Jurriaan Huskens 教授）
2008.07 - 2009.12 清华大学化学系　讲师
2009.12 - 2014.12 清华大学化学系 　副研究员
2014.12至今 清华大学化学系 教授
学术兼职ACS Biomaterials Science & Engineering副主编
《大学化学》编委会委员
《高等学校化学学报》青年执行编委
北京市化学会副秘书长
中国化学会化学学科教育委员会副主任
中国化学会青年工作者委员会委员
中国生物材料学会生物医用高分子材料分会委员
中国生物材料学会生物材料表界面工程分会第一届常务委员
中国生物物理学会纳米酶分会委员
研究领域含硒/碲高分子
研究组主页：http://xuslab.com
奖励与荣誉2017年获北京市高等教育教学成果奖二等奖（排名第一）
2017年中组部领军人才
2016年科技部中青年科技创新领军人才
2014年中组部青年拔尖
2014年自然科学基金委科学基金
2011年中国化学会青年化学奖
2011年教育部新世纪优秀人才支持计划
学术成果代表性论文：
1. Gao, S.; Li, T.; Guo, Y.; Sun, C.; Xianyu, B.; Xu, H.*: Selenium-Containing Nanoparticles Combine the NK Cells Mediated Immunotherapy with Radiotherapy and Chemotherapy. Adv. Mater., 2020, **.
2. Liu, C.; Fan, Z., Tan, Y.; Fan, F.; Xu, H.*: Tunable Structural Color Patterns Based on the Visible-Light-Responsive Dynamic Diselenide Metathesis. Adv. Mater., 2020, **.
3. Li, T.; Pan, S.; Zhuang, H.; Gao, S; Xu, H.*: Selenium-Containing Carrier-Free Assemblies with Aggregation-Induced Emission Property Combine Cancer Radiotherapy with Chemotherapy. ACS Appl. Bio Mater., 2020, 3, 1283.
4. Zhao, P.; Xia, J.; Cao, M.; Xu, H.*: Wavelength-Controlled Light-Responsive Polymer Vesicle Based on Se–S Dynamic Chemistry. ACS Macro Lett., 2020, 9, 163.
5. Li, T.; Pan, S.; Gao, S.*; Xiang, W.; Sun, C.; Cao, W.; Xu, H.*: Diselenide-Pemetrexed Assemblies for Combined Cancer Immuno-, Radio-, and Chemotherapies. Angew. Chem. Int. Ed., 2020, 132, 2722. (VIP paper)
6. Xia, J.; Li, H.*; Xu, H.*: Measuring the Strength of S/Se Based Dynamic Covalent Bonds. Acta Polym. Sin., 2020, 2, 205.
7. Fan, Z.; Xu, H.*: Recent Progress in the Biological Applications of Reactive Oxygen Species-Responsive Polymers. Polym. Rev. 2020, 60, 114.
8. Sun, C.; Wang, L.; Xianyu, B.; Li, T.; Gao, S.*; Xu, H.*: Selenoxide Elimination Manipulate the Oxidative Stress to Improve the Antitumor Efficacy. Biomaterials, 2019, 119514.
9. Cao, W.*; Xu, H.*: Selenium Containing Supra-amphiphiles. Mater. Chem. Front., 2019, 3, 2010.
10. Fan, F.; Liu, C.; Wang, S.; Lv, J.; Li, W.*; Fu, Y.*; Xu, H.*: Swelling-Induced 3D Photopatterning on a Diselenide-Containing Elastomer. J. Mater. Chem. C 2019, 7, 10777.
11. Xia, J.; Zhao, P.; Pan, S.; Xu, H.*: Diselenide-Containing Polymeric Vesicles with Osmotic Pressure Response. ACS Macro Letters 2019, 8, 629.
12. Wang, L.; Zhu, K.; Cao, W.*; Sun, C.; Lu, C.; Xu, H.*: ROS-triggered Degradation of Selenide-containing Polymers Based on Selenoxide Elimination. Polym. Chem. 2019, 10, 2039.
13. Xiang, W.; Li, Z.; Xu, C.; Li, J.*; Zhang, W.*; Xu, H.*: Quantifying the Bonding Strength of Gold-chalcogen Bonds in Block Copolymer Systems. Chem. Asian J. 2019, 14, 1481.
14. Liu, C.; Xia, J.; Ji, S.; Fan, Z.; Xu, H.*: Visible-Light-Induced Metathesis Reaction between Diselenide and Ditelluride. Chem. Commun., 2019, 55, 2813.
15. Xia, J.; Zhao, P.; Zheng, K.; Lu, C.; Yin, S.; Xu, H.*: Surface Modification Based on Diselenide Dynamic Chemistry: Towards Liquid Motion and Surface Bioconjugation. Angew. Chem. Int. Ed., 2019, 58, 542.
16. Li, F.*; Yang, D.; Xu, H.*: Nonmetal Heteroatom Doped Carbon dots: Synthesis and Property. Chem. Eur. J., 2019, 25, 1165.
17. Fan, F.; Ji, S.; Sun, C.; Liu, C.; Yu, Y.; Fu, Y.; Xu, H.*: Wavelength-Controlled Dynamic Metathesis: A Light-Driven Exchange Reaction Between Disulfide and Diselenide Bonds. Angew. Chem. Int. Ed., 2018, 57, 16426.
18. Fan, F.; Gao, S.; Ji, S.; Fu, Y.*; Zhang, P.*; Xu, H.*: Gamma Radiation Responsive Side-chain Tellurium-containing Polymer for Cancer Therapy. Mater. Chem. Front., 2018, 2, 2109.
19. Xia, J.; Li, T.; Lu, C.; Xu, H.*: Selenium-containing Polymer: Perspectives toward Diverse Applications in both Adaptive and Biomedical Materials. Macromolecules, 2018, 51, 7435.
20. Li, F.; Li, Y.; Yang, X.; Han, X.; Jiao, Y.; Wei, T.; Yang, D.; Xu, H.*; Nie, G.*: Highly Fluorescent Chiral N-S-Doped Carbon Dots from Cysteine: Affecting Cellular Energy Metabolism. Angew. Chem. Int. Ed., 2018, 57, 2377. (VIP paper)
21. Li, T.; Xiang, W.; Li, F.; Xu, H.*: Self-assembly Regulated Anticancer Activity of Platinum Coordinated Selenomethionine. Biomaterials, 2018, 157, 17.
22. Li, F.; Li, T.; Han, X.; Zhuang, H.; Nie, G.; Xu, H.*: Nanomedicine Assembled by Coordinated Selenium-Platinum Complexes Can Selectively Induce Cytotoxicity in Cancer Cells by Targeting the Glutathione Antioxidant Defense System. ACS Biomaterials Science & Engineering, 2018, 4, 1954(Biomaterials Science and Engineering in China Special Issue)
23. Zhou, W.; Li, H.; Xia, B.; Ji, W.; Ji, S.; Zhang, W.; Huang, W.*; Huo, F.*; Xu, H.*: Selenium-functionalized Metal-Organic Frameworks for Enzyme Mimics. Nano Research, 2018, 11, 5761.
24. Ji, S.; Fan, F.; Sun, C.; Yu, Y.; Xu, H.*: Visible Light Induced Plasticity of Shape Memory Polymers. ACS Appl. Mater. Interfaces, 2017, 9, 33169.
25. Wang, L.; Wang, W.; Cao, W.; Xu, H.*: Multi-hierarchical Responsive Polymers: Stepwise Oxidation of a Selenium- and Tellurium-Containing Block Copolymer with Sensitivity to both Chemical and Electrochemical Stimuli. Polym. Chem., 2017, 8, 4520.
26. Li, F.; Li, T.; Sun, C.; Xia, J.; Jiao, Y.; Xu, H.*: Selenium-Doped Carbon Quantum Dots (Se-CQDs) for Free Radical Scavenging. Angew. Chem. Int. Ed., 2017, 56, 9910.
27. Xia, J.; Li, F.; Ji, S.; Xu, H.*: Selenium-functionalized Graphene Oxide that Can Modulate the Balance of Reactive Oxygen Species. ACS Appl. Mater. Interfaces, 2017, 9, 21413.
28. Li, F.; Li, T.; Sun, C.; Xia, J.; Xu, H.*: Near-Infrared Light Stimuli-responsive Synergistic Therapy Nanoplatforms Based on the Coordination of Tellurium-containing Block Polymer and Cisplatin for Cancer Treatment. Biomaterials, 2017, 133, 208.
29. Ji, S.; El Mard, H.; Smet, M.; Dehaen, W.; Xu, H.*: Selenium Containing Macrocycles: Transformation between Se-N/Se-S/SeSe Bonds. Sci. China Chem., 2017, 60, 1191.
30. Sun, C.; Ji, S.; Li, F.*; Xu, H.*: Diselenide-Containing Hyperbranched Polymer with Light-Induced Cytotoxicity. ACS Appl. Mater. Interfaces, 2017, 9, 12924.
31. Zhou, W.; Wang, L.; Li, F.; Zhang, W.; Huang, W.*; Huo, F.*; Xu, H.*: Selenium-containing Polymer@metal-organic Frameworks Nanocomposites as an Efficient Multi-responsive Drug Delivery System. Adv. Funct. Mater., 2017, 27, **.
32. Xia, J.; Ji, S.; Xu, H.*: Diselenide Covalent Chemistry at the Interface: Stabilizing Asymmetric Diselenide-containing Polymer via Micelle Formation, Polym. Chem., 2016, 7, 6708.
33. Cao, W.; Li, F.; Chen, R.; Xu, H.*: Tellurium-containing Nanoparticles for Controlled Delivery of Cisplatin Based on Coordination Interaction, RSC Adv., 2016, 6, 94033.
34. Li, T.; Li, F.; Xiang, W.; Yi, Y.; Chen, Y.; Cheng, L.; Liu, Z.*; Xu., H.*: Selenium-containing Amphiphiles Reduced and Stabilized Gold Nanoparticles: Kill Cancer Cells via Reactive Oxygen Species, ACS Appl. Mater. Interfaces, 2016, 8, 22106.
35. Fan, F.; Wang, L.; Li, F.; Fu, Y.*; Xu, H.*: Stimuli-Responsive Layer-by-Layer Tellurium-Containing Polymer Films for the Combination of Chemotherapy and Photodynamic Therapy. ACS Appl. Mater. Interfaces, 2016, 8, 17004.
36. Wang, L.; Cao, W.; Xu, H.*: Tellurium-Containing Polymers: Towards Biomaterials and Optoelectronic Materials. ChemNanoMat, 2016, 2, 479.
37. Ji, S.; Xia, J.; Xu, H.*: Dynamic Chemistry of Selenium: Se–N and Se–Se Dynamic Covalent Bonds in Polymeric Systems. ACS Macro Lett., 2016, 5, 78.
38. Li, T.; Smet, M.; Dehaen, W. and Xu, H.*: Selenium–Platinum Coordination Dendrimers with Controlled Anti-Cancer Activity. ACS Appl. Mater. Interfaces, 2016, 8, 3609. (“Applied Materials and Interfaces in China” Special Issue)
39. Cao, W.; Wang, L.; Xu, H.*: Selenium/tellurium Containing Polymer Materials in Nanobiotechnology. Nano Today, 2015, 10, 717.
40. Ji, S.; Cao, W.; Yu, Y. and Xu, H.*: Visible-Light-Induced Self-Healing Diselenide-Containing Polyurethane Elastomer. Adv. Mater., 2015, 27, 7740.
41. Wang L.; Fan F.; Cao W. and Xu H.*: Ultra-sensitive ROS-responsive Coassemblies of Tellurium-Containing Molecules and Phospholipids, ACS Appl. Mater. Interfaces, 2015, 7, 16054.
42. Cao, W.; Gu, Y.; Li, T.; Xu, H.*: Ultra-sensitive ROS-responsive Tellurium-containing Polymers. Chem. Commun., 2015, 51, 7069.
43. Fang, R.; Xu, H.*; Cao, W.; Yang, L.; Zhang, X.*: Reactive Oxygen Species (ROS)-responsive Tellurium-containing Hyperbranched Polymer. Polym. Chem., 2015, 6, 2817.
44. Cao, W.; Wang, L.; Xu, H.*: Coordination Responsive Tellurium-containing Multilayer Film for Controlled Delivery. Chem. Commun., 2015, 51, 5520.
45. Huang, X.; Fang, R.; Wang, D.; Wang, J.; Xu, H.*; Wang, Y.*; Zhang, X.: Tuning Polymeric Amphiphilicity via Se-N Interactions: towards One-step Double Emulsion for Highly Selective Enzyme Mimics. Small, 2015, 11, 1537.
46. Li, T.; Yi, Y.; Xu, H.*: Selenium-containing Coordinating Assemblies with Selective Anti-cancer Activity: the Control of Reactive Oxygen Species. Acta Chim. Sinica, 2014, 72, 1209.
47. Wang, L.; Cao, W.; Yi, Y.; Xu, H.*: Dual Redox Responsive Co-assemblies of Diselenide-containing Block Copolymers and Polymer Lipids. Langmuir, 2014, 30, 5628.
48. Ji, S.; Cao, W.; Yu, Y.; Xu, H.*: Dynamic Diselenide Bonds: Exchange Reaction Induced by Visible Light without Catalysis. Angew. Chem. Int. Ed., 2014, 53, 6781. （Hot Paper）
49. Zeng, L.; Li, Y.; Li, T.; Cao, W.; Yi, Y.; Geng, W.; Sun, Z.*; Xu, H.*: Selenium-platinum Coordination Compounds as Novel Anticancer Drugs: Selectively Killing Cancer Cells via a ROS-mediated Apoptosis Route. Chem. Asian. J., 2014, 9, 2295.
50. Cao, W.; Gu, Y.; Meineck, M.; Li, T.; Xu, H.*: Tellurium-containing Polymer Micelles: Competitive-Ligand-Regulated Coordination Responsive Systems. J. Am. Chem. Soc., 2014, 136, 5132.
51. Cao, W.; Gu, Y.; Meineck, M.; Xu, H.*: The Combination of Chemotherapy and Radiotherapy towards More Efficient Drug Delivery. Chem. Asian. J., 2014, 9, 48 (Invited Focus Review).
52. Ji, S.; Cao, W.; Xu, H.*: A ROS Eliminating Nanocomposite Film Fabricated from Diselenide-Containing Polymer Micelles. Part. Part. Syst. Charact., 2013, 30, 1034.
53. Miao, X.; Cao, W.; Zeng, W.; Wang, J.; Gao, J.; Yang, C.; Kong, D.*; Xu, H.*; Wang, L.; Yang, Z.*: Switchable Catalytic Activity: Selenium-containing Peptides with Redox Controllable Self-assembly Property. Angew. Chem. Int. Ed., 2013, 52, 7781.
54. Ren, H.; Wu, Y.; Li, Y.; Cao, W.; Sun, Z.*; Xu, H.*; Zhang, X.: Visible Light Induced Disruption of Diselenide-Containing LbL Films: Toward Combination of Chemotherapy and Photodynamic Therapy. Small, 2013, 9, 3981.
55. Yi, Y.; Xu, H.*; Wang, L.; Cao, W.; Zhang, X.*: A Novel Dynamic Covalent Bond of Se-N: Towards Controlled Self-Assembly and Disassembly. Chem. Eur. J., 2013, 19, 9506.
56. Cao, W.; Zhang, X.; Miao, X.; Yang, Z.*; Xu, H.*: Gamma-ray Responsive Supramolecular Hydrogel Based on Diselenide-containing Polymer and Peptide. Angew. Chem. Int. Ed., 2013, 52, 6233.
57. Xu, H.*; Cao, W.; Zhang, X.*: Selenium-containing Polymers: Promising Biomaterials for Controlled Release and Enzyme Mimics. Acc. Chem. Res., 2013, 46, 1647.
58. Xu, H.*; Chen, D.; Wang, S.; Zhou, Y.; Sun, J.; Zhang, W.; Zhang, X.*: Macromolecular Self-Assembly and Nanotechnology in China. Phil. Trans. R. Soc. A, 2013, 371, **.
59. Han, P.; Li, S.; Cao, W.; Li, Y.; Sun, Z.; Wang, Z.; Xu, H.*: Red Light Responsive Diselenide-containing Block Copolymer Micelles. J. Mater. Chem. B, 2013, 1, 740.
60. Cao, W.; Li, Y.; Yi, Y.; Ji, S.; Zeng, L.; Sun, Z.*; Xu, H.*: Coordination-Responsive Selenium-Containing Polymer Micelles for Controlled Drug Release. Chem. Sci., 2012, 3, 3403.
61. Yi, Y.; Fa, S.; Cao, W.; Zeng, L.; Wang, M.; Xu, H.*; Zhang, X.: Fabrication of Well-Defined Crystalline Azacalixarene Nanosheets Assisted by Se？？？N Non-Covalent Interaction. Chem. Commun., 2012, 48, 7495.
62. Li, S.; Han, P.; Xu, H.*: Self-healing Polymeric Materials. (in Chinese) Progress in Chemistry, 2012, 24, 1346.
63. Fu, Y.; Chen, J.; Xu, H.*; Van Oosterwijck, C.; Zhang, X.; Dehaen, W.; Smet, M.*: Fully-branched Hyperbranched Polymers with Diselenide Core as Glutathione Peroxidase Mimics. Macromol. Rapid Commun., 2012, 33, 798. (Invited for Special Issue of “Polymer Science: the Next Generation”)
64. Xu, H.*; Sch？nhoff, M.; Zhang, X.: Unconventional Layer-by-Layer Assembly: Surface Molecular Imprinting and Its Applications. Small, 2012, 8, 517.
65. Ren, H.; Wu, Y.; Ma, N.; Xu, H.*; Zhang, X.: Side-chain Selenium-Containing Amphiphilic Block Copolymers: Redox-Controlled Self-Assembly and Disassembly. Soft Matter, 2012, 8, 1460. (Top ten most-read Soft Matter articles in December, 2011)
66. Ma, N.; Xu, H.*; An, L.; Li, J.; Sun, Z.; Zhang, X.*: Radiation-Sensitive Diselenide Block Copolymer Micellar Aggregates: Toward the Combination of Radiotherapy and Chemotherapy. Langmuir, 2011, 27, 5874.
67. Han, P.; Ma, N.; Ren, H.; Xu, H.*; Li, Z.; Wang, Z.*; Zhang, X.: Oxidation-Responsive Micelles Based on a Selenium-Containing Polymeric Superamphiphile. Langmuir, 2010, 26, 14414.
68. Ma, N.; Li, Y.; Ren, H.; Xu, H.*; Li, Z.; Zhang, X.*: Selenium-containing Block Copolymers and Their Oxidation-responsive Aggregates. Polym. Chem., 2010, 1, 1609. (Front cover page)
69. Liu, Z.; Yi, Y.; Xu, H.*; Zhang, X.; Ngo, T. H.; Smet, M.: Cation Selective Microcontact Printing Based on Surface Molecular Imprinted Layer-by-Layer Film. Adv. Mater., 2010, 22, 2689. (Highlighted by NPG Asia Materials)
70. Gao, J.; Liu, Y.; Xu, H.*; Wang, Z.; Zhang, X.*: Biostructure-like Surfaces with Thermally Responsive Wettability Prepared by Temperature Induced Phase Separation Micro-molding. Langmuir, 2010, 26, 9673.
71. Ma, N.; Li, Y.; Xu, H.*; Wang, Z.; Zhang, X.*: Dual Redox Responsive Assemblies Formed from Diselenide Block Copolymers. J. Am. Chem. Soc., 2010, 132, 442.
72. Xu, H.*; Huskens, J.*: Versatile Stamps in Microcontact Printing: Transferring Inks by Molecular Recognition and from Ink Reservoirs. Chem. Eur. J., 2010, 16, 2342.
73. Xu, H.*; Gomez-Casado, A.; Liu, Z.; Reinhoudt, D. N.; Lammertink, R. G. H.*; Huskens, J.*: Porous Multilayer-Coated PDMS Stamps for Protein Printing. Langmuir, 2009, 25, 13972.
74. Wang, Y.; Xu, H.; Zhang, X.*: Tuning the Amphiphilicity of Building Blocks: Controlled Self-assembly and Disassembly for Functional Supramolecular Materials. Adv. Mater., 2009, 21, 2849.
75. Gao, J.; Liu, Y.; Xu, H.*; Wang, Z.; Zhang, X.*: Mimicking Biological Structured Surfaces by Phase Separation Micromolding. Langmuir, 2009, 25, 4365.
76. Xu, H.; Ling, X.; van Bennekom, J.; Duan, X.; Ludden, M. J. W.; Reindoudt, D. N.; Wessling, M.; Lammertink, R. G. H.*; Huskens, J.*: Microcontact Printing of Dendrimers, Proteins, and Nanoparticles by Porous Stamps. J. Am. Chem. Soc., 2009, 131, 797.
77. Xu, H.; Wang, Y.; Wang, Z.*; Liu, J.; Smet, M.*; Dehaen, W.: Dendritic Tellurides Act as Antioxidant. Chinese Science Bulletin, 2006, 51, 2315.
78. Xu, H.; Gao, J.; Wang, Y.; Wang, Z.; Smet, M.*; Dehaen, W.; Zhang, X.*: Hyperbranched Polyselenides as Glutathione Peroxidase Mimics. Chem. Commun., 2006, 796.
79. Zhang, X.*; Xu, H.; Dong, Z.; Wang, Y.; Liu, J.*; Shen, J.: Highly Efficient Dendrimer-Based Mimic of Glutathione Peroxidase. J. Am. Chem. Soc., 2004, 126, 10556. (Highlighted by ACS Heart Cut)