文献详情
Construction and Characterization of a Mirror-Image l-DNA i-Motif
文献类型：期刊
通讯作者：Sun, YW (reprint author), China Univ Petr Huadong, Coll Chem Engn, State Key Lab Heavy Oil Proc, Qingdao 266580, Shandong, Peoples R China.; Liu, DS (reprint author), Tsinghua Univ, Dept Chem, Minist Educ, Key Lab Organ Optoelect & Mol Engn, Beijing 100084, Peoples R China.
期刊名称：CHEMBIOCHEM
年：2020
卷：21
期：1-2,SI
页码：94-97
ISSN：1439-4227
关键词：chirality; DNA structures; i-motifs; l-DNA; self-assembly
所属部门：化学系
摘要：The first thermally stable and pH-responsive quadruplex intercalated motif (i-motif) structure formed by l-DNA is presented. Although this l-type i-motif exhibits the same physiochemical properties as its d isomer, its inverted chirality and good enzymatic resistance potentially open the way to the development of new DNA materials of pharmaceutical and biological interest.
DOI：10.1002/cbic.201900576
百度学术：Construction and Characterization of a Mirror-Image l-DNA i-Motif
语言：外文
人气指数：1
浏览次数：1
基金：National Natural Science Foundation of ChinaNational Natural Science Foundation of China [21573288, 21573287]; Beijing National Science Foundation [Z180016]
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