李雅轩^1,2,
门彬^1,,,,
何怡¹,
刘美琪¹,
王东升^1,,
1. 中国科学院生态环境研究中心, 北京 100085;
2. 中国科学院大学, 北京 100049

作者简介: 李雅轩(1989-),女,博士,研究方向为纳米材料复合生物毒性,E-mail:nakea@foxmail.com.

通讯作者: 门彬,binmen@rcees.ac.cn ; 王东升,wgds@rcees.ac.cn

基金项目: 国家自然科学基金(21677156)


中图分类号: X171.5

The Combined Toxicity of Nanomaterial and Environmental Pollutants

Li Yaxuan^1,2,
Men Bin^1,,,,
He Yi¹,
Liu Meiqi¹,
Wang Dongsheng^1,,
1. Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China;
2. University of Chinese Academy of Sciences, Beijing 100049, China

Corresponding authors: Men Bin,binmen@rcees.ac.cn ; Wang Dongsheng,wgds@rcees.ac.cn

CLC number: X171.5

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摘要:纳米材料因其独特的物理化学性质,不仅其自身具有毒性,还会与共存污染物相互作用,影响彼此的迁移转化和毒性效应。文中总结了纳米复合污染毒性的研究方法,并介绍了几种纳米材料(碳纳米材料、金属氧化物、量子点和零价金属)与重金属或有机物复合时造成的生物毒性,包括不同层次毒性指标响应(生物整体、生物积累、大分子水平)和毒性机制的探讨,展望了纳米复合污染毒性领域今后的发展方向和亟待研究的重要问题。
关键词: 纳米材料/
生物毒性/
复合效应

Abstract:Nanomaterial possesses unique physical and chemical properties, which leads to its inherent toxicity and interaction with co-existed pollutans, thus alterring each others' transportation and toxic effects. This review summarised the research method of combined toxicity of nanomaterial. Additionally, the combined toxicity of nanomaterial (carbon nanomaterial, metal oxide, quantum dot and zero-valent metal) with heavy metals or organic pollutants were introduced, including diffenrent levels of biomarkers, such as entire body, bioaccumulation and biomacromolecule, as well as toxicity mechanism. Moreover, the future development direction and important problems in the field of nanomaterial combined toxicity are prospected.
Key words:nanomaterial/
biotoxicity/
combined effects.