安成才 邮  箱：chcaian@pku.edu.cn
职  称：教授
办公室地址：北京市海淀区颐和园路5号，北京大学，金光生命科学大楼，100871
实验室地址：北京市海淀区颐和园路5号，北京大学，金光生命科学大楼，100871


个人简介
科研领域
代表性论文
教育经历:1989 - 1992 , 理学博士 , 植物分子生物学 , 日本岗山大学
1987 - 1989 , 理学硕士 , 植物病理 , 日本三重大学
1977 - 1980 , 毕业 , 植物保护 , 东北林业大学
荣誉奖励:北京大学首届产学研合作先进个人奖, 2013
北京大学教学优秀奖, 2004
北京大学桐山奖教金优秀奖, 2001
英国牛津大学访问学者, 1997
英国De Montfort大学兼职研究员, 1995
工作经历:2001 - 至今,　　 教授,　　　　　　　北京大学生命科学学院
1997 - 1998,　　访问学者,　　　　　 英国牛津大学
1995 - 2001,　　副教授,　　　　　　 北京大学生命科学学院
1993 - 1995,　　博士后,　　　　　　 北京大学
1992 - 1993,　　客座研究员,　　　　 日本岗山大学
1982 - 1983,　　进修,　　　　　　　 武汉大学
1980 - 1985,　　任教,　　　　　　　 东北林业大学
社会服务工作:北京大学首届产学研合作先进个人奖, 2013
北京大学教学优秀奖, 2004
北京大学桐山奖教金优秀奖, 2001
英国牛津大学访问学者, 1997
英国De Montfort大学兼职研究员, 1995
执教课程:植物分子生物学（本科生）, 讲课, 北京大学, 1998年－暂停
基因表达与调控（研究生）, 讲课, 北京大学, 1994年－至今 春季学期
研究兴趣：
1、植物抗病免疫反应的分子机理：
（1）植物介导激素信号途径调控抗病免疫反应的分子机制
（2）植物超敏细胞死亡的信号通路及其调控机理
2、植物营养组织中异位合成与积累三酰甘油（TAG）的代谢转换调控机制
1．Wu Q, Zhang X, Peirats LM, Belda PB, Wang XF, Cui S, Yu XC, Rodriguezb PL*., An CC*., Ubiquitin Ligases RGLG1 and RGLG5 Regulate Abscisic Acid Signaling by Controlling the Turnover of Phosphatase PP2CA. Plant cell, 2016, doi:10.1105/ tpc.16.00364.
2．Zhang X, Wu Q, Cui S, Ren J, Qian WQ, Yang Y, He SP, Chu JF, Sun XH, Yan CY, Yu XC and An CC*., Hijacking of the jasmonate pathway by the mycotoxin fumonisin B1 (FB1) to initiate programmed cell death in Arabidopsis is modulated by RGLG3 and RGLG4. J. of Exp. Bot., 2015, Vol., 66(9): 2709–2721.
3．Yang L, Li BS, Zheng XY, Li J, Yang M, Dong XN, He GM*, An CC* and Deng XW*, Enhanced Salicylic Acid Biosynthesis Is Involved in Increased Resistance to Biotrophic Bacterial Pathogen in Arabidopsis Hybrids. Nature Communications, 2015, (6:7309), DOI: 10.1038/ncomms8309.
4．Yinfei Kong, Songbin Chen, Yang Yang, and Chengcai An* , ABA-insensitive (ABI) 4 and ABI5 synergistically regulate DGAT1 expression in Arabidopsis seedlings under stress , FEBS Letters , 2013 , Vol., 587:3076–3082.
5．Liwen Fu, Xiangchun Yu, and Chengcai An* , Overexpression of constitutively active OsCPK10 increases Arabidopsis resistance against Pseudomonas syringae pv. tomato and rice resistance against Magnaporthe grisea , Plant Physiology and Biochemistry , 2013, Vol., 73: 202-210.
6．Xu Zhang, Qian Wu, Jiao Ren, Wanqiang Qian, Shanping He, Kuowei Huang, XiangChun Yu, Yin Gao, Ping Huang, and Chengcai An* , Two Novel RING-Type Ubiquitin Ligases, RGLG3 and RGLG4, Are Essential for Jasmonate-Mediated Responses in Arabidopsis , Plant Physiology , 2012 , Vol. 160: 1–15.
7．Xu Zhang, Qian Wu and Chengcai An* , RGLG3 and RGLG4, novel ubiquitin ligases modulating jasmonate signaling , Plant Signaling & Behavior , 2012 , Vol., 7(12):1-3.
8．Shuanglei Kong, Xinyao Liu, Liwen Fu, Xiangchun Yu, Chengcai An* , I-PfoP3I: A Novel Nicking HNH Homing Endonuclease Encoded in the Group I Intron of the DNA Polymerase Gene in Phormidium foveolarum Phage Pf-WMP3 , PLoS ONE , 2012 , Vol: 7(8): e43738.
9．Yang Yang, Xiangchun Yu, Lianfen Song, and Chengcai An* , ABI4 Activates DGAT1 Expression in Arabidopsis Seedlings during Nitrogen Deficiency , Plant Physiology , 2011 , Vol. 156: 873–883.
10．Shanping He, Kuowei Huang, Xu Zhang, Xiangchun Yu, Ping Huang, Chengcai An* , The LSD1-Type Zinc Finger Motifs of Pisum sativa LSD1 Are a Novel Nuclear Localization Signal and Interact with Importin Alpha , PLoS ONE , 2011 , Vol. 6(7): e22131.
11．Yang Yang, Xiangchun Yu, Lianfen Song, and Chengcai An* , Nitrogen Deficiency System is Helpful in Characterizing Regulation Mechanisms of Ectopic Triacylglycerol Accumulation in Arabidopsis Seedlings , Plant Signaling & Behavior , 2011 , Vol., 6(12):1-2.
12．Shanping He, Guihong Tan, Qian Liu, Kuowei Huang, Jiao Ren, Xu Zhang, Xiangchun Yu, Ping Huang, Chengcai An* , The LSD1-Interacting Protein GILP Is a LITAF Domain Protein That Negatively Regulates Hypersensitive Cell Death in Arabidopsis , PLoS ONE , 2011 , Vol. 6(4): e18750.
13．Jiayu Gu, Ye Wang, Xu Zhang, Shihua Zhang, Yin Gao, Chengcai An* , Identification of gibberellin acid-responsive proteins in rice leaf sheath using proteomics , Frontiers in Bioscience , 2010 , 15: 854-867.
14．CHE NanYing, YANG Yang, LI YanDong, WANG LiLi, HUANG Ping, GAO Yin & An ChengCai* , Efficient LEC2 activation of OLEOSIN expression requires two neighboring RY elements on its promoter , Sci China Ser C-Life Sci , 2009 , 52(9): 854-863.
15．Nanying Che, Lili Wang, Yin Gao, Chengcai An* , Soluble expression and one-step purification of a neurotoxin Huwentoxin-I in Escherichia coli , Protein Expression and Purification , 2009 , 65: 154–159.
16．Xinyao Liu & Shuanglei Kong & Miao Shi & Liwen Fu & Yin Gao & Chengcai An* , Genomic Analysis of Freshwater Cyanophage Pf-WMP3 Infecting Cyanobacterium Phormidium foveolarum: The Conserved Elements for a Phage , Microbial Ecology , 2008 , 56:671-680.
17．Li Xu, Ye Wang, Lijiang Wang, Yin Gao, Chengcai An* , TYchi, a novel chitinase with RNA N-glycosidase and anti-tumor activities , Frontiers in Bioscience , 2008 , 13: 3127-3135.
18．Li Xu, Lijiang Wang, Tao Liu, Wanqiang Qian, Yin Gao, Chengcai An* , Triton, a novel family of miniature inverted-repeat transposable elements (MITEs) in Trichosanthes kirilowii Maximowicz and its effect on gene regulation , BBRC , 2007 , 364: 668-674.
19．Xinyao Liu, Miao Shi, Shuanglei Kong, Yin Gao, Chengcai An* , Cyanophage Pf-WMP4, a T7-like phage infecting the freshwater cyanobacterium Phormidium foveolarum: Complete genome sequence and DNA translocation , Virology , 2007 , 366: 28–39.
20．Tao Liu, Jia-yu Gu, Chen-jia Xu, Yin Gao, Cheng-cai An* , Overproduction of OsSLRL2 alters the development of transgenic Arabidopsis plants , BBRC , 2007 , 358: 983–989.
21．Wanqiang Qian, Guihong Tan, Shanping He, Xinyue Zhang, Xu Zhang, Yin Gao, Hongxia Liu and Chengcai An* , Identification of a new AT-rich-element binding factor PsATF1 and its combined effect with PsGBF on the activation of PsCHS1 promoter , Frontiers in Bioscience , 2007 , Vol. 12: 1670-1679.
22．Wanqiang Qian ? Guihong Tan ? Hongxia Liu ? Shanping He ? Yin Gao ? Chengcai An* , Identification of a bHLH-type G-box binding factor and its regulation activity with G-box and Box I elements of the PsCHS1 promoter , Plant Cell Rep , 2006 , 23: 85-93.
23．Miao Shi, Li Zou, Xinyao Liu, Yin Gao, Zhongkai Zhang, Weizhong Wu, Donghui Wen, Zhangliang Chen and Chengcai An* , A novel bacterium Saprospira sp. strain PdY3 forms bundles and lyses cyanobacteria , Frontiers in Bioscience , 2006 , 11: 1916-1923.
24．Liu Xinyao, Shi Miao, Liao Yonghong, Gao Yin, Zhang Zhongkai, Wen Donghui, Wu Weizhong and An Chencai* , Feeding Characteristics of an Amoeba (Lobosea: Naegleria) Grazing Upon Cyanobacteria: Food Selection, Ingestion and Digestion Progress , Microbial Ecology , 2006 , 51: 315–325.
25．Xin-Yue Zhang, Ye Wu, Jin-Yuan Yan, Yin Gao, Ye Wang, Shuang-Li Mi, Cheng-Cai An* , Y55 and D78 are crucial amino acid residues of a new IgE epitope on trichosanthin , BBRC , 2006 , 343(4):1251-1256.
26．Ye Wang, Shuang-li Mi, Mei-yan Lou, Yin Gao, Zhang-liang Chen and ChengCai An* , Enhanced green fluorescence protein tracks trichosanthin in human choriocarcinoma cells as a feasible and stable reporter , Frontiers in Bioscience , 2005 , 10, 2279-2284.
27．Wenjie Ji, Xinyue Zhang, Huicong Hu, Jiyuan Chen, Yin Gao, Songping Liang, Chengcai An* , Expression and puriWcation of Huwentoxin-I in baculovirus system , Protein Expression and Purification , 2005 , 41(2):454-458.
28．Guihong Tan, Yin Gao, Miao Shi, Xinyue Zhang, Shanping He, Zhangliang Chen and Chengcai An* , SiteFinding-PCR: a simple and efficient PCR method for chromosome walking , Nucleic Acids Research , 2005 , Vol. 33, No. 13 e122.
29．Shuang-li Mi, Cheng-cai An*, Ye Wang, Ji-yuan Chen, Nan-ying Che, Yin Gao and Zhang-liang Chen , Trichomislin, a novel ribosome-inactivating protein, induces apoptosis that involves mitochondria and caspase-3 , Archives of Biochemistry and Biophysics , 2005 , 434(2): 258-265.
30．L. Wang, C. An*, W. Qian, T. Liu, J. Li, Z. Chen , Detection of the putative cis-region involved in the induction by a Pyricularia oryzae elicitor of the promoter of a gene encoding phenylalanine ammonia-lyase in rice , Plant Cell Rep , 2004 , 22:513–518.
31．Yan Yuanxin, An Chengcai*, Li Li, Gu Jiayu, Tan Guihong and Chen Zhangliang , T-linker Specific Ligation PCR (T-linker-PCR): An advanced PCR technique for chromosome walking or for isolation of tagged DNA ends , Nucleic Acids Research , 2003 , Vol. 31(12): 1-7 e68.
32．Chunyang Zhang, Chengcai An*, Rongying Wang, Yixuan Gong, Hui Ma, Dieyan Chen & Zhangliang Chen , Capillary Electrophoresis and Circular Dichroism Study of Trichosanthin and Its Mutants , Talanta , 2002 , 57: 467-473.
33．Chun-yang ZHANG, Yi-xuan GONG, Hui MA*, Cheng-cai AN*, Die-yan CHEN and Zhang-liang CHEN , Reactive oxygen species involved in trichosanthin-induced apoptosis of human choriocarcinoma cells , Biochem. J. , 2001 , 355, 653-661.