The Plant Cell
Abstract
Panicle size and grain number are important agronomic traits and influence grain yield in rice (Oryza sativa), but the molecular and genetic mechanisms underlying panicle size and grain number control remain largely unknown in crops. Here we report thatLARGE2encodes a HECT-domain E3 ubiquitin ligase OsUPL2 and regulates panicle size and grain number in rice. The loss of functionlarge2mutants produce large panicles with increased grain number, wide grains and leaves, and thick culms.LARGE2regulates panicle size and grain number by repressing meristematic activity.LARGE2is highly expressed in young panicles and grains. Biochemical analyses show that LARGE2 physically associates with ABERRANT PANICLE ORGANIZATION1 (APO1) and APO2, two positive regulators of panicle size and grain number, and modulates their stabilities. Genetic analyses support thatLARGE2functions withAPO1andAPO2in a common pathway to regulate panicle size and grain number. These findings reveal a novel genetic and molecular mechanism of the LARGE2-APO1/APO2 module-mediated control of panicle size and grain number in rice, suggesting that this module is a promising target for improving panicle size and grain number in crops.
| 论文编号: | DOI:10.1093/plcell/koab041 |
| 论文题目: | The LARGE2-APO1/APO2 Regulatory Module Controls Panicle Size and Grain Number in Rice |
| 英文论文题目: | The LARGE2-APO1/APO2 Regulatory Module Controls Panicle Size and Grain Number in Rice |
| 第一作者: | Luojiang Huang, Kai Hua, Ran Xu, Dali Zeng, Ruci Wang, Guojun Dong, Guozheng Zhang, Xueli Lu, Na Fang, Dekai Wang, Penggen Duan, Baolan Zhang, Zupei Liu, Na Li, Yuehua Luo, Qian Qian, Shanguo Yao, Yunhai Li |
| 英文第一作者: | Luojiang Huang, Kai Hua, Ran Xu, Dali Zeng, Ruci Wang, Guojun Dong, Guozheng Zhang, Xueli Lu, Na Fang, Dekai Wang, Penggen Duan, Baolan Zhang, Zupei Liu, Na Li, Yuehua Luo, Qian Qian, Shanguo Yao, Yunhai Li |
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| 发表年度: | 2021-03-10 |
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| 摘要: | Panicle size and grain number are important agronomic traits and influence grain yield in rice (Oryza sativa), but the molecular and genetic mechanisms underlying panicle size and grain number control remain largely unknown in crops. Here we report thatLARGE2encodes a HECT-domain E3 ubiquitin ligase OsUPL2 and regulates panicle size and grain number in rice. The loss of functionlarge2mutants produce large panicles with increased grain number, wide grains and leaves, and thick culms.LARGE2regulates panicle size and grain number by repressing meristematic activity.LARGE2is highly expressed in young panicles and grains. Biochemical analyses show that LARGE2 physically associates with ABERRANT PANICLE ORGANIZATION1 (APO1) and APO2, two positive regulators of panicle size and grain number, and modulates their stabilities. Genetic analyses support thatLARGE2functions withAPO1andAPO2in a common pathway to regulate panicle size and grain number. These findings reveal a novel genetic and molecular mechanism of the LARGE2-APO1/APO2 module-mediated control of panicle size and grain number in rice, suggesting that this module is a promising target for improving panicle size and grain number in crops. |
| 英文摘要: | Panicle size and grain number are important agronomic traits and influence grain yield in rice (Oryza sativa), but the molecular and genetic mechanisms underlying panicle size and grain number control remain largely unknown in crops. Here we report thatLARGE2encodes a HECT-domain E3 ubiquitin ligase OsUPL2 and regulates panicle size and grain number in rice. The loss of functionlarge2mutants produce large panicles with increased grain number, wide grains and leaves, and thick culms.LARGE2regulates panicle size and grain number by repressing meristematic activity.LARGE2is highly expressed in young panicles and grains. Biochemical analyses show that LARGE2 physically associates with ABERRANT PANICLE ORGANIZATION1 (APO1) and APO2, two positive regulators of panicle size and grain number, and modulates their stabilities. Genetic analyses support thatLARGE2functions withAPO1andAPO2in a common pathway to regulate panicle size and grain number. These findings reveal a novel genetic and molecular mechanism of the LARGE2-APO1/APO2 module-mediated control of panicle size and grain number in rice, suggesting that this module is a promising target for improving panicle size and grain number in crops. |
| 刊物名称: | The Plant Cell |
| 英文刊物名称: | The Plant Cell |
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| 其它备注: | Luojiang Huang, Kai Hua, Ran Xu, Dali Zeng, Ruci Wang, Guojun Dong, Guozheng Zhang, Xueli Lu, Na Fang, Dekai Wang, Penggen Duan, Baolan Zhang, Zupei Liu, Na Li, Yuehua Luo, Qian Qian, Shanguo Yao, Yunhai Li. The LARGE2-APO1/APO2 Regulatory Module Controls Panicle Size and Grain Number in Rice. The Plant Cell. DOI:10.1093/plcell/koab041 |
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