Trends in Plant Science
Abstract
In photosynthetic cells, chloroplasts and mitochondria are the sites of the core redox reactions underpinning energy metabolism. Such reactions generate reactive oxygen species (ROS) when oxygen is partially reduced. ROS signaling leads to responses by cells which enable them to adjust to changes in redox status. Recent studies in Arabidopsis thaliana reveal that chloroplast NADH can be used to generate malate which is exported to the mitochondrion where its oxidation regenerates NADH. Oxidation of this NADH produces mitochondrial ROS (mROS) which can activate signaling systems to modulate energy metabolism, and in certain cases can lead to Programmed Cell Death (PCD). We propose the term ‘malate circulation’ to describe such redistribution of reducing equivalents to mediate energy homeostasis in the cell.
| 论文编号: | DOI:10.1016/j.tplants.2020.01.010 |
| 论文题目: | Malate Circulation: Linking Chloroplast Metabolism to Mitochondrial ROS |
| 英文论文题目: | Malate Circulation: Linking Chloroplast Metabolism to Mitochondrial ROS |
| 第一作者: | Yannan Zhao, Hong Yu, Jian-Min Zhou, Steven M. Smith, Jiayang Li |
| 英文第一作者: | Yannan Zhao, Hong Yu, Jian-Min Zhou, Steven M. Smith, Jiayang Li |
| 联系作者: | |
| 英文联系作者: | |
| 外单位作者单位: | |
| 英文外单位作者单位: | |
| 发表年度: | 2020-03-06 |
| 卷: | |
| 期: | |
| 页码: | |
| 摘要: | In photosynthetic cells, chloroplasts and mitochondria are the sites of the core redox reactions underpinning energy metabolism. Such reactions generate reactive oxygen species (ROS) when oxygen is partially reduced. ROS signaling leads to responses by cells which enable them to adjust to changes in redox status. Recent studies in Arabidopsis thaliana reveal that chloroplast NADH can be used to generate malate which is exported to the mitochondrion where its oxidation regenerates NADH. Oxidation of this NADH produces mitochondrial ROS (mROS) which can activate signaling systems to modulate energy metabolism, and in certain cases can lead to Programmed Cell Death (PCD). We propose the term ‘malate circulation’ to describe such redistribution of reducing equivalents to mediate energy homeostasis in the cell. |
| 英文摘要: | In photosynthetic cells, chloroplasts and mitochondria are the sites of the core redox reactions underpinning energy metabolism. Such reactions generate reactive oxygen species (ROS) when oxygen is partially reduced. ROS signaling leads to responses by cells which enable them to adjust to changes in redox status. Recent studies in Arabidopsis thaliana reveal that chloroplast NADH can be used to generate malate which is exported to the mitochondrion where its oxidation regenerates NADH. Oxidation of this NADH produces mitochondrial ROS (mROS) which can activate signaling systems to modulate energy metabolism, and in certain cases can lead to Programmed Cell Death (PCD). We propose the term ‘malate circulation’ to describe such redistribution of reducing equivalents to mediate energy homeostasis in the cell. |
| 刊物名称: | Trends in Plant Science |
| 英文刊物名称: | Trends in Plant Science |
| 论文全文: | |
| 英文论文全文: | |
| 全文链接: | |
| 其它备注: | Yannan Zhao, Hong Yu, Jian-Min Zhou, Steven M. Smith, Jiayang Li. Malate Circulation: Linking Chloroplast Metabolism to Mitochondrial ROS. Trends in Plant Science. DOI:10.1016/j.tplants.2020.01.010 |
| 英文其它备注: | |
| 学科: | |
| 英文学科: | |
| 影响因子: | |
| 第一作者所在部门: | |
| 英文第一作者所在部门: | |
| 论文出处: | |
| 英文论文出处: | |
| 论文类别: | |
| 英文论文类别: | |
| 参与作者: | |
| 英文参与作者: |
