Science
Abstract
Because environmentally degrading inorganic fertilizer use underlies current worldwide cereal yields, future agricultural sustainability demands enhanced nitrogen use efficiency. We found that genome-wide promotion of histone H3 lysine 27 trimethylation (H3K27me3) enables nitrogen-induced stimulation of rice tillering: APETALA2-domain transcription factor NGR5 (NITROGEN-MEDIATED TILLER GROWTH RESPONSE 5) facilitates nitrogen-dependent recruitment of polycomb repressive complex 2 to repress branching-inhibitory genes via H3K27me3 modification. NGR5 is a target of gibberellin receptor GIBBERELLIN INSENSITIVE DWARF1 (GID1)–promoted proteasomal destruction. DELLA proteins (characterized by the presence of a conserved aspartate-glutamate-leucine-leucine-alanine motif) competitively inhibit the GID1-NGR5 interaction and explain increased tillering of green revolution varieties. Increased NGR5 activity consequently uncouples tillering from nitrogen regulation, boosting rice yield at low nitrogen fertilization levels. NGR5 thus enables enhanced nitrogen use efficiency for improved future agricultural sustainability and food security.
| 论文编号: | DOI:10.1126/science.aaz2046 |
| 论文题目: | Enhanced Sustainable Green Revolution Yield via Nitrogen-responsive Chromatin Modulation in Rice |
| 英文论文题目: | Enhanced Sustainable Green Revolution Yield via Nitrogen-responsive Chromatin Modulation in Rice |
| 第一作者: | Kun Wu, Shuansuo Wang, Wenzhen Song, Jianqing Zhang, Yun Wang, Qian Liu, Jianping Yu, Yafeng Ye, Shan Li, Jianfeng Chen, Ying Zhao, Jing Wang, Xiaokang Wu, Meiyue Wang, Yijing Zhang, Binmei Liu, Yuejin Wu, Nicholas P. Harberd & Xiangdong Fu |
| 英文第一作者: | Kun Wu, Shuansuo Wang, Wenzhen Song, Jianqing Zhang, Yun Wang, Qian Liu, Jianping Yu, Yafeng Ye, Shan Li, Jianfeng Chen, Ying Zhao, Jing Wang, Xiaokang Wu, Meiyue Wang, Yijing Zhang, Binmei Liu, Yuejin Wu, Nicholas P. Harberd & Xiangdong Fu |
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| 发表年度: | 2020-02-07 |
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| 摘要: | Because environmentally degrading inorganic fertilizer use underlies current worldwide cereal yields, future agricultural sustainability demands enhanced nitrogen use efficiency. We found that genome-wide promotion of histone H3 lysine 27 trimethylation (H3K27me3) enables nitrogen-induced stimulation of rice tillering: APETALA2-domain transcription factor NGR5 (NITROGEN-MEDIATED TILLER GROWTH RESPONSE 5) facilitates nitrogen-dependent recruitment of polycomb repressive complex 2 to repress branching-inhibitory genes via H3K27me3 modification. NGR5 is a target of gibberellin receptor GIBBERELLIN INSENSITIVE DWARF1 (GID1)–promoted proteasomal destruction. DELLA proteins (characterized by the presence of a conserved aspartate-glutamate-leucine-leucine-alanine motif) competitively inhibit the GID1-NGR5 interaction and explain increased tillering of green revolution varieties. Increased NGR5 activity consequently uncouples tillering from nitrogen regulation, boosting rice yield at low nitrogen fertilization levels. NGR5 thus enables enhanced nitrogen use efficiency for improved future agricultural sustainability and food security. |
| 英文摘要: | Because environmentally degrading inorganic fertilizer use underlies current worldwide cereal yields, future agricultural sustainability demands enhanced nitrogen use efficiency. We found that genome-wide promotion of histone H3 lysine 27 trimethylation (H3K27me3) enables nitrogen-induced stimulation of rice tillering: APETALA2-domain transcription factor NGR5 (NITROGEN-MEDIATED TILLER GROWTH RESPONSE 5) facilitates nitrogen-dependent recruitment of polycomb repressive complex 2 to repress branching-inhibitory genes via H3K27me3 modification. NGR5 is a target of gibberellin receptor GIBBERELLIN INSENSITIVE DWARF1 (GID1)–promoted proteasomal destruction. DELLA proteins (characterized by the presence of a conserved aspartate-glutamate-leucine-leucine-alanine motif) competitively inhibit the GID1-NGR5 interaction and explain increased tillering of green revolution varieties. Increased NGR5 activity consequently uncouples tillering from nitrogen regulation, boosting rice yield at low nitrogen fertilization levels. NGR5 thus enables enhanced nitrogen use efficiency for improved future agricultural sustainability and food security. |
| 刊物名称: | Science |
| 英文刊物名称: | Science |
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| 其它备注: | Kun Wu, Shuansuo Wang, Wenzhen Song, Jianqing Zhang, Yun Wang, Qian Liu, Jianping Yu, Yafeng Ye, Shan Li, Jianfeng Chen, Ying Zhao, Jing Wang, Xiaokang Wu, Meiyue Wang, Yijing Zhang, Binmei Liu, Yuejin Wu, Nicholas P. Harberd & Xiangdong Fu. Enhanced Sustainable Green Revolution Yield via Nitrogen-responsive Chromatin Modulation in Rice. Science. DOI:10.1126/science.aaz2046 |
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