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DJ-1 is dispensable for human stem cell homeostasis

本站小编 Free考研考试/2022-01-02

Fang Cheng1,7,
Si Wang2,4,7,
Moshi Song2,7,8,
Zunpeng Liu3,7,
Ping Liu1,7,
Lei Wang1,7,
Yanjiang Wang5,
Qian Zhao4,
Kaowen Yan2,
Piu Chan4,
Weiqi Zhang4,6,7,8,,,
Jing Qu3,7,8,,,
Guang-Hui Liu1,4,7,8,9,,
1 National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China;
2 State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China;
3 State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China;
4 Advanced Innovation Center for Human Brain Protection, National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital Capital Medical University, Beijing 100053, China;
5 Department of Neurology, Daping Hospital, Third Military Medical University, Chongqing 400042, China;
6 CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China;
7 University of Chinese Academy of Sciences, Beijing 100049, China;
8 Institute for Stem cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China;
9 Translational Medical Center for Stem Cell Therapy, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China
Funds: This work was supported by the National Key Research and Development Program of China (2017YFA0102802), the Strategic Priority Research Program of the Chinese Academy of Sciences (XDA16010100), Major Program of Development Fund for Shanghai Zhangjiang National Innovation Demonstration Zone (ZJ2018-ZD-004), the National Key Research and Development Program of China (2018YFC2000100, 2015CB964800, 2017 YFA0103304, 2018YFA0107203, 2017YFA0504000, 2019YFA011 0100), the National Natural Science Foundation of China (Grant Nos. 81625009, 91749202, 91749123, 31671429, 81671377, 8177 1515, 31601158, 81701388, 81601233, 31601109, 81822018, 8187 0228, 81801399, 31801010, 81801370, 81861168034, 81921006, 81922027, 31900523, 81901432, 31900524, 81901433), Beijing Natural Science Foundation (Z190019), Beijing Municipal Commission of Health and Family Planning (PXM2018_026283_000002), Advanced Innovation Center for Human Brain Protection (3500-1192012), the State Key Laboratory of Membrane Biology and Youth Innovation Promotion Association, CAS (to LW).






Abstract



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