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Low-dose quercetin positively regulates mouse healthspan

本站小编 Free考研考试/2022-01-02

Lingling Geng1,2,
Zunpeng Liu3,4,5,
Si Wang2,6,
Shuhui Sun2,6,
Shuai Ma2,6,
Xiaoqian Liu3,5,
Piu Chan1,
Liang Sun7,
Moshi Song2,5,8,,
Weiqi Zhang4,5,8,,
Guang-Hui Liu1,2,5,6,8,9,,
Jing Qu3,5,8,
1 Advanced Innovation Center for Human Brain Protection, National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital Capital Medical University, Beijing 100053, China;
2 State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China;
3 State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China;
4 Key Laboratory of Genomics and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China;
5 University of Chinese Academy of Sciences, Beijing 100049, China;
6 National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China;
7 The MOH Key Laboratory of Geriatrics, Beijing Hospital, National Center of Gerontology, Beijing 100730, China;
8 Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China;
9 Beijing Institute for Brain Disorders, Beijing 100069, China
Funds: This work was supported by the Strategic Priority Research Program of the Chinese Academy of Sciences (XDA16010100), the National Key Research and Development Program of China (2015CB964800, 2018YFC2000100, 2017YFA0102802, 2017YFA0103304, 2018YFA0107203), the National Natural Science Foundation of China (Grant Nos. 81625009, 81330008, 91749202, 91749123, 31671429, 81671377, 81771515, 31601158, 81701388, 81601233, 81571385, 31601109, 81822018, 81870228, 81801399, 31801010, 81801370, 81861168034), Beijing Municipal Commission of Health and Family Planning (PXM2018_026283_000002), Advanced Innovation Center for Human Brain Protection (3500-1192012) and the State Key Laboratory of Membrane Biology.






Abstract



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