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Phosphorylation of PLIN3 by AMPK promotes dispersion of lipid droplets during starvation

本站小编 Free考研考试/2022-01-02

Jianxi Zhu1,2,
Mingyang Xu1,
Yi Liu1,
Lisha Zhuang1,
Kejun Ying1,
Feng Liu1,
Dan Liu3,
Wenbin Ma1,2,,
Zhou Songyang1,2,3,
1 MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory for Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, China;
2 Guangzhou Regenerative Medicine and Health-Guangdong Laboratory(GRMH-GDL), Guangzhou 510530, China;
3 Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
Funds: the Welch Foundation (Q-1673 and I-1441) and CPRITRP160462, and the C-BASS Shared Resource at the Dan L. Duncan Cancer Center (DLDCC) of Baylor College of Medicine (P30CA125123).
This work was supported by the National Key Research and Development Program of China (2017YFA0102801, 2018YFA0107 003), National Natural Science Foundation of China (Grant Nos. 91640119, 91749113, 81330055, 31570827 and 31871479), Guangzhou Science and Technology Project (201605030012), Natural Science Foundation of Guangdong Province (2017A03031 3116) and Guangdong Science and Technology Department Planning Project (2015B020228002). We would also like to acknowledge the support of the NIH (HL131744 and CA211653)






Abstract



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