Nature Methods, 09 September, 2019，DOI：https://doi.org/10.1038/s41592-019-0544-2
Molecular resolution imaging by repetitive optical selective exposure
Lusheng Gu, Yuanyuan Li, Shuwen Zhang, Yanhong Xue, Weixing Li, Dong Li, Tao Xu & Wei Ji
Abstract
We introduce an interferometric single-molecule localization method for super-resolution fluorescence microscopy. Fluorescence molecules are located by the intensities of multiple excitation patterns of an interference fringe, providing around a twofold improvement in the localization precision compared with the conventional imaging with the same photon budget. We demonstrate this technique by resolving nanostructures down to 5 nm in size over a large 25 × 25 μm² field of view.
文章链接：https://www.nature.com/articles/s41592-019-0544-2
相关报道：http://www.ibp.cas.cn/kyjz/zxdt/201909/t20190909_5378749.html


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