基本信息
周炳升男博导中国科学院水生生物研究所
电子邮件： bszhou@ihb.ac.cn
通信地址： 中科院水生所
邮政编码： 430072

研究领域

招生信息
招生专业071004-水生生物学

招生方向环境毒理学


教育背景
学历
学位

工作经历
工作简历2005-01~现在,中国科学院水生生物研究所,研究员
2003-07~2004-12,香港城市大学,博士后
2001-07~2003-06,McMaster大学,博士后

社会兼职2018-12-01-今,Chemosphere, 杂志编委
2017-05-05-今,aquatic toxicology, 杂志编委
2015-01-01-2016-12-31,杂志编委,
2014-06-09-今,杂志编委,
2010-03-01-2013-05-01,科学通报、环境化学、生态毒理学报, 编委


教授课程水生生物学


专利与奖励
奖励信息
专利成果

出版信息
发表论文（1）Multigenerational Disruption of the Thyroid Endocrine System in Marine Medaka after a Life-Cycle Exposure to Perfluorobutanesulfonate,Environ Sci Technol,2018,第11作者
（2）Dysregulation of Intestinal Health by Environmental Pollutants: Involvement of the Estrogen Receptor and Aryl Hydrocarbon Receptor,Environ Sci Technol,2018,第11作者
（3）Dysbiosis of gut microbiota by chronic coexposure to titanium dioxide nanoparticles and bisphenol A: Implications for host health in zebrafish,Environmental Pollution,2018,第11作者
（4）Developmental neurotoxicity of triphenyl phosphate in zebrafish larvae,Aquatic Toxicology,2018,第11作者
（5）Endocrine disruption in Chinese rare minnow (Gobiocypris rarus) after long-term exposure to low environmental concentrations of progestin megestrol acetate,Ecotoxicology & Environmental Safety,2018,第11作者
（6）A protective role of autophagy in TDCIPP-induced developmental neurotoxicity in zebrafish larvae,Aquatic Toxicology,2018,第11作者
（7）Transgenerational endocrine disruption and neurotoxicity in zebrafish larvae after parental exposure to binary mixtures of decabromodiphenyl ether (BDE-209) and lead. Environmental Pollution 230, 96-106.,Environmental Pollution,2017,第11作者
（8）The involvement of autophagy and cytoskeletal regulation in TDCIPP-induced SH-SY5Y cell differentiation,NeuroToxicology,2017,第11作者
（9）Identification of Molecular Targets for 4,5-Dichloro-2-n-octyl-4-isothiazolin-3-one (DCOIT) in Teleosts: New Insight into Mechanism of Toxicity,Environmental Science &Technology,2017,第11作者
（10）Tris (1, 3-dichloro-2-propyl) phosphate induces apoptosis and autophagy in SH-SY5Y cells: Involvement of ROS-mediated AMPK/mTOR/ULK1 pathways,Food & Chemical Toxicology,2017,第11作者
（11）Tris (1, 3-dichloro-2-propyl) phosphate-induced apoptotic signaling pathways in SH-SY5Y neuroblastoma cells,NeuroToxicology,2017,第11作者
（12）Effect of combined exposure to lead and decabromodiphenyl ether on neurodevelopment of zebrafish larvae,Chemosphere,2016,第11作者
（13）The binary mixtures of megestrol acetate and 17α-ethynylestradiol adversely affect zebrafish reproduction,environmental pollution,2016,第11作者
（14）High-throughput transcriptome sequencing reveals the combined effects of key e-waste contaminants, decabromodiphenyl ether (BDE-209) and lead, in zebrafish larvae,environmental pollution,2016,第11作者
（15）Enhanced Bioconcentration of Bisphenol A in the Presence of Nano-TiO2 Can Lead to Adverse Reproductive Outcomes in Zebrafish,environmental science and technology,2016,第11作者
（16）The progestin levonorgestrel affects sex differentiation in zebrafish at environmentally relevant concentrations.,Aquatic Toxicology,2015,第11作者
（17）The impact of long term exposure to phthalic acid esters on reproduction in Chinese rare minnow (Gobiocypris rarus),Environmental Pollution,2015,第11作者
（18）Adverse outcome pathway: Framework, application, and challenges in chemical risk assessment,Journal of Environmental Sciences,2015,第11作者
（19） Developmental exposure to the organophosphorus flame retardant Tris(1,3-dichloro-2-propyl) phosphate: estrogenic activity, endocrine disruption and reproductive effects on zebrafish,aquatic toxicology,2015,第11作者
（20）The developmental neurotoxicity of PBDEs: Effect of DE-71 on dopamine in zebrafish larvae,environmental toxicology and chemistry,2015,第11作者
（21） Effect of titanium dioxide nanoparticles on the bioavailability, metabolism, and toxicity of pentachlorophenol in zebrafish larvae,Journal of Hazardous Materials,2015,第11作者
（22）Bioconcentration, Metabolism and Neurotoxicity of the Organophorous Flame Retardant 1,3-dichloro 2-propyl phosphate (TDCPP) to Zebrafish,aquatic toxicology,2015,第11作者
（23）Bioconcentration and Transfer of the Organophorous Flame Retardant 1,3-dichloro 2-propyl phosphate (TDCPP) Causes Thyroid Endocrine Disruption and Developmental Neurotoxicity in Zebrafish Larvae,environmental science and technology,2015,第11作者
（24）The synthetic progestin megestrol acetate adversely affects zebrafish reproduction,Aquatic Toxicology,2014,第11作者
（25）Acute exposure to DE-71 causes alterations in visual behavior in zebrafish larvae,Environmental Toxicology and Chemistry ,2013,第11作者
（26）Endocrine disruption by di-(2-ethylhexyl)-phthalate in Chinese rare minnow (Gobiocypris rarus). ,Environmental Toxicology and Chemistry ,2013,第11作者
（27）Thyroid endocrine system disruption by pentachlorophenol: an in vitro and in vivo assay., Aquatic Toxicology,2013,第11作者
（28）Exposure of zebrafish embryos/larvae to TDCPP alters concentrations of thyroid hormones and transcriptions of genes involved in the hypothalamic-pituitary-thyroid axis, Aquatic Toxicolog,2013,第11作者
（29）Acute exposure to DE-71: Effects on locomotor behavior and developmental neurotoxicity in zebrafish larvae,Environmental Toxicology and Chemistry ,2012,第11作者
（30）Prenatal transfer of polybrominated diphenyl ethers (PBDEs) results in developmental neurotoxicity in zebrafish larvae,Environmental Science and Technology ,2012,第11作者
（31）Disruption of endocrine function in in vitro H295R cell-based and in in vivo assay in zebrafish by 2,4-dichlorophenol,Aquatic Toxicology ,2012,第11作者
（32）Bioconcentration and metabolism of decabromodiphenyl ether (BDE-209) result in thyroid endocrine disruption in zebrafish larvae,Aquatic Toxicology ,2012,第11作者
（33）Alterations in retinoid status after long-term exposure to PBDEs in zebrafish (Danio rerio),Aquatic Toxicology ,2012,第11作者
（34）Effects of prochloraz or propylthiouracil on the cross-talk between the HPG, HPA and HPT Axes in zebrafish,Environmental Science Technology,2011,第11作者
（35）Effects of fluorotelomer alcohol 8:2 FTOH on steroidogenesis in H295R cells: Targeting the cAMP signalling cascade,Toxicology Applied Pharmacology ,2010,第11作者
（36）The role of Nrf2 and MAPK pathways in PFOS-induced oxidative stress in zebrafish embryos,Toxicological Sciences,2010,第11作者
（37）Exposure to DE-71 alters thyroid hormone levels and gene transcription in the hypothalamic–pituitary–thyroid axis of zebrafish larvae,Aquatic Toxicology,2010,第11作者
（38）Protein Profiles in Zebrafish (Danio rerio) Embryos Exposed to PFOS,Toxicological Sciences,2009,（39）Waterborne exposure to fluorotelomer alcohol 6:2 FTOH alters plasma sex hormone and gene transcription in the hypothalamic–pituitary–gonadal (HPG) axis of zebrafish,Aquatic Toxicology,2009,（40）HBCD-induced developmental toxicity and apoptosis in zebrafish embryos,Aquatic Toxicology,2009,（41）Waterborne exposure to PFOS causes disruption of the hypothalamus-pituitary-thyroid axis in zebrafish larvae ,Chemosphere,2009,（42） ,Developmental toxicity and alteration of gene expression in zebrafish embryos exposed to PFOS. , 230: 23-32. ,Toxicology and Applied Pharmacology,2008,（43）DE-71-induced apoptosis involving intracellular calcium and the Bax-mitochondria-caspase protease pathway in human neuroblastoma cells in vitro,Toxicological Sciences,2008,
发表著作（ 1 ） 持久性有机污染物的内分泌干扰效应,科学出版社,2018-06,第1作者


科研活动
科研项目（ 1 ） 典型持久性有机污染物的环境过程与毒性效应, 参与,国家级,2009-01--2012-12
（ 2 ） 水环境中孕激素类污染物对斑马鱼的内分泌干扰效应和分子机制, 主持,国家级,2013-01--2016-12
（ 3 ） 有机农药和含铜、锌无机农药的协同毒性作用机理, 参与,国家级,2013-01--2017-12
（ 4 ） 气体过饱和、有机污染物和重金属等关键环境因子的鱼类生物学效应研究, 参与,研究所（学校）,2013-01--2015-12
（ 5 ） 典型支流库湾的水环境背景调查与生态安全评估, 参与,研究所（学校）,2013-01--2015-12
（ 6 ） 电子废弃物溴代阻燃剂和重金属复合污染的人体暴露评价技术研究, 参与,国家级,2013-01--2016-12
（ 7 ） 污染物的内分泌干扰效应与发育毒性机制, 主持,部委级,2014-06--2018-06
（ 8 ） 纳米TiO2与典型有机污染物的复合暴露对斑马鱼的毒性效应, 主持,国家级,2016-01--2019-12
（ 9 ） 新兴溴代阻燃剂的水环境暴露、毒性效应及分子机制, 主持,国家级,2018-01--2022-12
（ 10 ） 典型养殖系统对自然水域生态系统的影响机理, 主持,国家级,2018-12--2022-12

参与会议

合作情况
项目协作单位

指导学生