基本信息
张英 男 大连化学物理研究所
电子邮件：zhangying@dicp.ac.cn
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部门/实验室：研究生部
研究领域生物医用材料，细胞工程

招生信息招生专业：生物化工
招生方向：动物细胞规模化培养

招生专业081703-生物化工
083100-生物医学工程

招生方向



教育背景
学历研究生
学位博士

工作经历• 2007.6-2011.9 中国科学院大连化学物理研究所 生物技术部 助理研究员
• 2011.10-现在 中国科学院大连化学物理研究所 生物技术部 副研究员

工作简历
社会兼职

教授课程
博士研究生专业课生化分离工程

专利与奖励
奖励信息
专利成果

出版信息发表论文：

1 Ying Zhang,Wei Wang, etc. In vivo culture of encapsulated endostatin-CHO cells forsystemic tumor inhibition. Human Gene Therapy. 18 (5): 474-481, 2007.
2 Ying Zhang,Wei Wang, etc. Tumor Anti-angiogenic Gene Therapy with MicroencapsulatedRecombinant CHO Cells. Annals of Biomedical Engineering. 35 (4): 605-614, 2007.
3 Ying Zhang,Wei Wang, etc. Optimization of Microencapsulated Recombinant CHO Cell Growth,Endostatin Production and Stability of Microcapsule in vivo. J Biomed Mater ResPart B: Appl Biomater 84B: 79-88, 2008.
4 Ying Zhang,Jing Zhou, etc. Optimization of the Seeding Density in MicroencapsulatedRecombinant CHO Cell Culture. Chem. Biochem. Eng. Q. 22 (1) : 105-111, 2008.
5 Qi Wen tao,Zhang Ying, etc. Optimization of the cell seeding density and modeling of cellgrowth and metabolism using themodified Gompertz model for microencapsulatedanimal cell culture. Biotechnology and Bioengineering. (93): 887-895, 2006.
6 Huaining Teng,Ying Zhang, etc. Inhibition of Tumor Growth in Mice by Endostatin Derived fromAbdominal Transplanted Encapsulated Cell. Acta Biochim Biophys Sinica. 39 (4):278-284, 2007.
7 Li N, ZhangY*, Xiu ZL, Wang Y, Chen L, Wang SJ, Guo X, Ma XJ*.Thepreservation of isletwith alginate encapsulation in the process of transportation. Biotechnology andApplied Biochemistry. 2015, 62 (4): 530-536.
8Li N,Zhang Y*, Liu Y, Xiu ZL, Tan MQ, Li S, Guo X, Wang Y, Chen L, Song YZ, Yu WT,Lv GJ, Ma XJ*. Improvedislet purity by the hypertonic-hypotonic method.International Journal of Artificial Organs. 2015,37 (6): 477-485.
9 Li S, ZhangY*, Chen L, Li N, Xie HG, Guo X, Zhao S, Yu WT, Lv Y, Lv GJ, Wu HJ*, Ma XJ. Therelationship between the inflammatory response and cell adhesion onalginate-chitosan-alginate microcapsules after transplantation. Journal ofbiomedical materials research part A. 2015,103 (7): 2333-2343.
10 Deng F, ChenL, Zhang Y*, Zhao S, Wang Y, Li N, Li S, Guo X, Ma XJ. Development of abioreactor based on magnetically stabilized fluidized bed for bioartificialliver. Bioprocess and biosystems engineering. 2015, 38 (12): 2369-2377.
11 Wang Y,Zhang Y*, Li N, Chen L, Zhang DM, Sun DS, Lv GJ, Yu WT, Guo X, Ma XJ*. Growthand Production of Microencapsulated recombinant CHO in a stirred tankbioreactor. Bioprocess and biosystems engineering. 2015,38 (7): 1303-1312.
12Wang Y,Zhang Y*, Li N, Chen L, Zhang DM, Sun DS, Li S, Guo X, Ma XJ*. Stirring rateregulates the proliferation and metabolism of microencapsulated recombinant CHOcells. Biotechnology and AppliedBiochemistry.2015,62(6): 833-839.
13 Huang PY,Zhang LD, Gao YM, He ZY, Yao D, Wu ZT, Cen J, Chen XT, Liu CC, Hu YP, Lai DM,Hu ZL, Chen L, Zhang Y, Cheng X, Ma XJ, Pan GY, Wang X, Hui LJ*. DirectReprogramming of Human Fibroblasts to Functional and Expandable Hepatocytes.Cell Stem Cell. 2014,14: 370-384.
14 Chen L, ZhangY*, Li S, Li N, Wang Y, Guo X, Zhao S, Yu WT, Sun GW, Liu Y, Ma XJ*. Effect ofplasma components on the stability and permeability of microcapsule. Journal ofBiomedical Materials Research: Part A. 2014, 102(7): 2408-2416.
15 Zhao W, ZhangY*, Liu Y, Tan MQ, Yu WT, Xie HG, MaYing, Sun GW, Lv GJ, Zhao S, Ma XJ*.Oxygen diffusivity in alginate/chitosan microcapsules. Journal of ChemicalTechnology and Biotechnology. 2013, 88(3): 449-455.
16 Ma Y, ZhangY*, Liu Y, Chen L, Zhao W, Sun GW, Li N, Wang Y, Guo X, Lv GJ, Ma XJ*.Investigation of alginate–?-poly-L- lysine microcapsules for cellmicroencapsulation. Journal ofBiomedical Materials Research Part A. 2013, 101A (5): 1265-1273.
17Ma Y,Zhang Y*, Wang Y, Wang QY, Tan MQ, Liu Y, Chen L, Li N, Yu WT, Ma XJ*. Study ofthe effect of membrane thickness on microcapsule strength, permeability, andcell proliferation. Journal of Biomedical Materials Research PartA. 2013,101A(4): 1007-1015.
18Ma Y,Zhang Y*, Zhao S, Wang Y, Wang SR, Zhou Y, Li N, Xie HG, Yu WT, Liu Y, Wang W,Ma XJ*. Modeling and optimization of membrane preparation conditions of thealginate-based microcapsules with response surface methodology. Journal ofBiomedical Materials Research Part A. 2012, 100A (4): 989-998.
19Yu WT，SongHY，ZhengGS，Liu XD，Zhang Y，MaXJ*. Study on membrane characteristics of alginate-chitosan microcapsule withcell growth. Journal of Membrane Science. 2011,337: 214-220.
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发表著作：
1）Ying Zhang ,Xiudong Liu, Weiting Yu, Guojun Lv, Jing Zhu, Wei Wang, Xiaojun Ma.“The Artificial Organ: Cell Encapsulation” ComprehensiveBiotechnology, 2nd edition. Elsevier Press. 2011.
2）Sun GW, Xu XX, LiN, Zhang Y, Ma XJ. “Three-dimensional culture for expansion anddifferentiation of mouse embryonic stem cells”. Human Embryonic andInduced Pluripotent Stem Cells: Lineage-Specific Differentiation Protocols.Humana Press Inc., Totowa, NJ, 2011.
3）王为，张英，马小军。 第35章《胰岛损伤与再生》。《再生医学原理与实践》第三版。上海科学技术出版社。2011年。







科研活动科研项目：
1. 国家自然科学基金面上项目：细胞间质体外模拟系统的构建及物质传递基本规律的研究
2. 辽宁省博士启动基金：新型流化床生物人工肝的研究
3. 大连市优秀青年科技人才基金：肿瘤治疗用重组蛋白药物递释系统的研究
4. 生物反应器工程国家重点实验室开放课题：基于微囊化肝细胞的新型流化床生物人工肝的研究

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