基本信息
张维绮女中国科学院北京基因组研究所
电子邮件： zhangwq@big.ac.cn
通信地址： 北京市朝阳区北辰西路1号院104号楼
邮政编码： 100101

研究领域
1. 人类衰老的内外因素及其相互作用
2. 延缓衰老的潜在干预手段及其机制
3. 基于人多能干细胞的疾病模拟和药物筛选



招生信息生化、分子、细胞、基因组学与生物信息学及理科类

招生专业071009-细胞生物学

招生方向遗传学，基因组学、生物化学与分子生物学、生物信息学


教育背景2005-09--2011-06北京大学博士
2001-09--2005-06南昌大学学士


工作经历?






工作简历2019-02~现在,中国科学院北京基因组研究所,研究员
2016-12~2019-01,中国科学院生物物理研究所,研究员
2015-10~2016-11,中国科学院生物物理研究所,副研究员
2011-10~2015-09,中国科学院生物物理研究所,助理研究员


出版信息
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Selected Publications
1. Shuai Ma#, Shuhui Sun#, Lingling Geng#, Moshi Song#, Wei Wang, Yanxia Ye, Qianzhao Ji, Zhiran Zou, Si Wang, Xiaojuan He, Wei Li, Concepcion Rodriguez Esteban, Xiao Long, Guoji Guo, Piu Chan, Qi Zhou, Juan Carlos Izpisua Belmonte*, Weiqi Zhang*, Jing Qu* and Guang-Hui Liu* (2020). "Caloric Restriction Reprograms the Single-Cell Transcriptional Landscape of Rattus Norvegicus Aging." Cell 180(5): p. 984-1001 e22. (*Co-corresponding author)
2. Si Wang#, Yuxuan Zheng#, Jingyi Li#, Yang Yu#, Weiqi Zhang#, Moshi Song, Zunpeng Liu, Zheying Min, Huifang Hu, Ying Jing, Xiaojuan He, Liang Sun, Lifang Ma, Concepcion Rodriguez Esteban, Piu Chan, Jie Qiao, Qi Zhou, Juan Carlos Izpisua Belmonte*, Jing Qu*, Fuchou Tang* and Guang-Hui Liu* (2020). "Single-Cell Transcriptomic Atlas of Primate Ovarian Aging." Cell 180(3): 585-600.e519. (#Co-first author)
3. Weiqi Zhang#, Haifeng Wan#, Guihai Feng#, Jing Qu#, Jiaqiang Wang, Yaobin Jing, Ruotong Ren, Zunpeng Liu, Linlin Zhang, Zhiguo Chen, Shuyan Wang, Yong Zhao, Zhaoxia Wang, Yun Yuan, Qi Zhou, Wei Li*, Guang-Hui Liu* and Baoyang Hu* (2018). "Sirt6 Deficiency Results in Developmental Retardation in Cynomolgus Monkeys." Nature 560(7720): 661-665. (#Co-first author)
4. Weiqi Zhang#, Jingyi Li#, Keiichiro Suzuki#, Jing Qu#, Ping Wang, Junzhi Zhou, Xiaomeng Liu, Ruotong Ren, Xiuling Xu, Alejandro Ocampo, Tingting Yuan, Jiping Yang, Ying Li, Liang Shi, Dee Guan, Huize Pan, Shunlei Duan, Zhichao Ding, Mo Li, Fei Yi, Ruijun Bai, Yayu Wang, Chang Chen, Fuquan Yang, Xiaoyu Li, Zimei Wang, Emi Aizawa, April Goebl, Rupa Devi Soligalla, Pradeep Reddy, Concepcion Rodriguez Esteban, Fuchou Tang*, Guang-Hui Liu* and Juan Carlos Izpisua Belmonte* (2015). "A Werner Syndrome Stem Cell Model Unveils Heterochromatin Alterations as a Driver of Human Aging." Science 348(6239): 1160-1163. (#Co-first author)
5. Nard Kubben, Weiqi Zhang#, Lixia Wang, Ty C. Voss, Jiping Yang, Jing Qu#, Guang-Hui Liu* and Tom Misteli* (2016). "Repression of the Antioxidant Nrf2 Pathway in Premature Aging." Cell 165(6): 1361-1374. (#Co-senior author)
6. Weiqi Zhang#, Jing Qu, Guang-Hui Liu* and Juan Carlos Izpisua Belmonte* (2020). "The Ageing Epigenome and Its rejuvenation." Nature Reviews Molecular Cell Biology 21(3): 137-150. (#First author)
7. Lingling Geng#, Zunpeng Liu#, Weiqi Zhang#*, Wei Li, Zeming Wu, Wei Wang, Ruotong Ren, Yao Su, Peichang Wang, Liang Sun, Zhenyu Ju, Piu Chan, Moshi Song*, Jing Qu* and Guang-Hui Liu* (2019). "Chemical Screen Identifies a Geroprotective Role of Quercetin in Premature Aging." Protein & Cell 10(6): 417-435. (#Co-first author) and (*Co-corresponding author)
8. Lingling Geng#, Zunpeng Liu#, Si Wang#, Shuhui Sun#, Shuai Ma, Xiaoqian Liu, Piu Chan, Liang Sun, Moshi Song*, Weiqi Zhang*, Guang-Hui Liu* and Jing Qu* (2019). "Low-Dose Quercetin Positively Regulates Mouse Healthspan." Protein & Cell 10(10): 770-775. (*Co-corresponding author)
9. Pengze Yan, Qingqing Li, Lixia Wang, Ping Lu, Keiichiro Suzuki, Zunpeng Liu, Jinghui Lei, Wei Li, Xiaojuan He, Si Wang, Jianjian Ding, Piu Chan, Weiqi Zhang#, Moshi Song#, Juan Carlos Izpisua Belmonte#, Jing Qu*, Fuchou Tang*, and Guang-Hui Liu*. (2019). "Foxo3-Engineered Human Esc-Derived Vascular Cells Promote Vascular Protection and Regeneration." Cell Stem Cell 24(3): 447-461.e448. (#Co-senior author)