基本信息
张驰宇男 博导中国科学院上海巴斯德研究所
电子邮件： zhangcy1999@ips.ac.cn
通信地址： 上海市岳阳路320号
邮政编码： 200025


研究领域新病原发现及鉴定；分子诊断；病毒遗传多样性

招生信息
招生专业071005-微生物学

招生方向新病原发现与鉴定
病原检测技术研发
病毒遗传多样性及进化


教育背景1998-09--2003-07中科院研究生院/昆明动物研究所博士
1994-09--1998-06河南师范大学 生物系学士

学历博士

学位博士

工作经历
工作简历2015-05~2015-08,加州大学圣地亚哥分校,高级访问
2012-04~现在,中科院上海巴斯德研究所,研究员
2003-08~2012-03,江苏大学 生命科学研究院,讲师、副教授

社会兼职2015-01-06-今,Medicine 编委,
2014-12-06-今,BMC Infect Dis编委,
2013-05-26-2014-12-06,Biomed Res Int 编委,
2011-07-26-今,PLoS ONE 编委, 编委


教授课程病毒诊断与流行病学


专利与奖励
获奖（1） 浙江省科技进步奖, 三等奖, 省级, 2014
（2） 镇江市科技进步奖, 二等奖, 市地级, 2010
（3） 镇江市科技进步奖, 二等奖, 市地级, 2009
（4） 云南省自然科学奖, 二等奖, 省级, 2006

专利成果（ 1 ） 一种同时检测人冠状病毒229E，OC43，NL63和HKU1的实时荧光多重RT-PCR方法, 发明, 2015, 第 1 作者, 专利号: 6.6
（ 2 ） 一种双脱氧核苷修饰的引物方法、反应体系及其在突变检测中的应用, 发明, 2013, 第 1 作者, 专利号: 7.4
（ 3 ） 一种结核分枝杆菌利福平耐药突变的检测方法及试剂盒和应用, 发明, 2014, 第 1 作者, 专利号: 3.1
（ 4 ） 基于环介导的等温扩增的人呼吸道合胞病毒检测试剂盒, 发明, 2013, 第 4 作者, 专利号: 6.7
（ 5 ） 用于检测多种病原体的荧光实时检测方法及应用, 发明, 2017, 第 1 作者, 专利号: 20**
（ 6 ） 用于检测突变体的荧光实时检测试剂及方法, 发明, 2017, 第 1 作者, 专利号: 20**


出版信息
发表论文（1）Metagenomic analysis identified co-infection with human rhinovirus C and bocavirus 1 in an adult suffering from severe pneumonia,J Infect,2017,通讯作者
（2）A novel quantitative PCR mediated by high-fidelity DNA polymerase,Sci Report,2017,通讯作者
（3）A Simple Visual Detection Method of Human Zika Virus Using Reverse Transcription Loop Mediated Isothermal Amplification,J Bacteriol Parasitol,2017,通讯作者
（4）Identification of two new HIV-1 circulating recombinant forms (CRF87_cpx and CRF88_BC) from reported unique recombinant forms in Asia.,AIDS Res Hum Retroviruses.,2017,通讯作者
（5）First description of two new HIV-1 recombinant forms CRF82_cpx and CRF83_cpx among drug users in Northern Myanmar.,Virulence.,2017,通讯作者
（6）First appearance of HIV-1 CRF07_BC and CRF08_BC outside China.,AIDS Res Hum Retroviruses.,2017,通讯作者
（7）Phylogeographic analysis of severe fever with thrombocytopenia syndrome virus from Zhoushan Islands, China: implication for transmission across the ocean.,Sci Report,2016,通讯作者
（8）Epidemiological and clinical characteristics of respiratory viral infections in children in Shanghai, China.,Arch Virol,2016,通讯作者
（9）Subtype distribution of hepatitis C virus in Jiangsu, China.,J Med Virol,2016,通讯作者
（10）A melting curve-based multiplex RT-qPCR assay for simultaneous detection of four human coronaviruses,Int J Mol Sci.,2016,通讯作者
（11）HCV diversity among Chinese and Burmese IDUs in Dehong, Yunnan, China.,PLoS ONE,2016,通讯作者
（12）A Novel Real-time Reverse Transcription-Polymerase Chain Reaction Assay with Partially Double-Stranded Linear DNA Probe for Sensitive Detection of Hepatitis C Viral RNA.,J Virol Methods.,2016,通讯作者
（13）The dynamics of the HIV epidemic among men who have sex with men (MSM) from 2005 to 2012 in Shenzhen, China.,Sci Rep,2016,通讯作者
（14）Modified proofreading PCR for detection of point mutation, insertion and deletion using a ddNTP-blocked primer,PLoS ONE,2015,通讯作者
（15）Characterization of the major bacterial-fungal populations colonizing dandruff scalps in Shanghai, China, shows microbial disequilibrium,Exp Dermatol.,2015,通讯作者
（16）Phylogenetic analysis of the major causative agents of hand, foot and mouth disease in Suzhou city, Jiangsu province, China, in 2012–2013,Emerg Microbes Infect ,2015,通讯作者
（17）Origin and outbreak of HIV-1 CRF55_01B among MSM in Shenzhen, China,JAIDS,2014,通讯作者
（18）Persistent detection of the H7N9 among poultry in Huzhou city, China, in summer, 2013,Int J Infect Dis,2014,通讯作者
（19）Diverse forms of HIV-1 among Burmese long-distance truck drivers imply their contribution to HIV-1 cross-border transmission,BMC Infect Dis,2014,通讯作者
（20）Genetic Variation of human respiratory syncytial virus among children with fever and respiratory symptoms in Shanghai, China, from 2009 to 2012,Infect Genet Evol,2014,通讯作者
（21）Co-circulation of three HA and two NA subtypes of avian influenza viruses in Huzhou, China, April 2013: implication for the origin of the novel H7N9 virus,J Virol,2014,通讯作者
（22）Epidemiological link between exposure to poultry and all influenza A(H7N9) confirmed cases in Huzhou city, China, March to May 2013,Euro surveill,2013,通讯作者
（23）Complex patterns of HCV epidemic in Suzhou: evidence for dual infection and HCV recombination in East China,J Clin Virol, ,2012,通讯作者
（24）Extensive and complex HIV-1 recombination between B’, C and CRF01_AE among IDUs in south-east Asia.,AIDS,2012,第1作者
（25）Co-evolution of Primate SAMHD1 and Lentivirus Vpx Leads to the Loss of the vpx Gene in HIV-1 Ancestor. ,PLoS ONE,2012,通讯作者
（26）Phylodynamics of HIV-1 unique recombinant forms in China-Myanmar border: implication for HIV-1 transmission to Myanmar from Dehong, China,Infect Genet Evol,2012,通讯作者
（27）Evolutionary dynamics of the interferon-induced transmembrane gene family in vertebrates,PLoS ONE,2012,通讯作者
（28）Phylogeographic Analyses Reveal a Crucial Role of Xinjiang in HIV-1 CRF07_BC and HCV 3a Transmissions in Asia.,PLoS ONE,2011,通讯作者
（29）Evolutionary history of the vertebrate mitogen activated protein kinases family. ,PLoS ONE,2011,通讯作者
（30）HCV Subtype Characterization among Injection Drug Users: Implication for a Crucial Role of Zhenjiang in HCV Transmission in China.,PLoS ONE,2011,通讯作者
（31）Hepatitis C Virus Infection among Injection Drug Users in Zhenjiang, Jiangsu, China. ,India J Virol ,2011,通讯作者
（32）Epidemiology of hand, foot, and mouth disease and genotype characterization of Enterovirus 71 in Jiangsu, China.,J Clin Virol ,2010,通讯作者
（33）Molecular Evolution of the Primate Antiviral Restriction Factor Tetherin.,PLoS ONE,2010,通讯作者
（34）Complex positive selection pressures drive the evolution of HIV-1 with different coreceptor tropisms,Sci China-Life Sci ,2010,通讯作者
（35）Genome-wide and molecular evolution analyses of phospholipase D gene family in Poplar and Grape. ,BMC Plant Biol ,2010,第2作者
（36）Chromosomes as interdependent accounting units. The assigned orientation of C. elegans chromosomes minimizes the total W-base Chargaff difference.,J Biol Sys ,2010,第2作者
（37）Rapid increasing prevalence of HIV and syphilis and HIV-1 subtype characterization of HIV among men who have sex with men in Jiangsu, China. ,Sex Transm Dis,2009,通讯作者
（38）Molecular evolution of novel swine-origin A/H1N1 influenza viruses among and before human,Virus Genes ,2009,通讯作者
（39）Predicted co-receptor tropism and sequence characteristics of China HIV-1 V3 loops: implications for the future usage of CCR5 antagonists and AIDS vaccine development.,Int J Infect Dis ,2009,通讯作者
（40）Near full-length genome characterization of an HIV-1 CRF01_AE strain in Jiangsu, China: evidence of two independent introduction from Fujian. ,AIDS Res Hum Retroviruses ,2009,通讯作者
（41）First detection of a novel HIV-1 CRF01_AE/07_BC recombinant among an epidemiologically linked cohort of IDUs in Jiangsu, China.,AIDS Res Hum Retroviruses,2009,通讯作者

发表著作

科研活动
科研项目（ 1 ） 中缅越老边境地区高危人群HIV-1分子流行病学、病毒进化及跨境传播动力学研究, 主持,国家级,2014-01--2017-12
（ 2 ） 宿主蛋白RBMX调控HIV-1潜伏感染的分子机制研究, 主持,国家级,2017-01--2020-12
（ 3 ） 常见病毒病现场检测新技术及生物安全四级实验室相关病毒检测, 主持,国家级,2017-01--2020-12
（ 4 ） TOTAL项目（法国）：手足口病的流行病学和进化动力学, 主持,研究所（学校）,2015-01--2018-12
（ 5 ） 西非和南亚邻国媒介生物携带病原谱及新病原发现, 主持,研究所（学校）,2018-01--2020-12

参与会议

合作情况
项目协作单位

指导学生已指导学生
张亚楠**
现指导学生
傅雪敏**
马英英**