基本信息
于军男博导中国科学院北京基因组研究所
电子邮件： junyu@big.ac.cn
通信地址： 朝阳区北辰西路1号院104#
邮政编码： 100101

研究领域

招生信息
招生专业
招生方向脊椎动物基因组学，基因组结构与功能，表型可塑性研究
生物信息学，基因功能网络与结构
研发DNA和RNA新测序技术


教育背景1984-09--1990-06纽约大学医学院博士学位

学历
学位

工作经历
工作简历1998-03~现在,中国科学院北京基因组研究所,研究员
1993-07~2000-03,美国华盛顿大学基因组中心,Senior Fellow
1990-07~1993-06,纽约大学医学院泌尿系,Research Assistant Professor
1984-09~1990-06,纽约大学医学院,博士学位

社会兼职

教授课程生命组学
基因组学
基因组学概述
发现生命奥秘
英文生物论文写作
生物专业英语论文写作基本方法与技巧概要
生物信息学进展系列讲座
公共关系


专利与奖励
奖励信息（1） 2014年中国分析测试协会科学技术奖, 一等奖, 其他, 2014
（2） 2013年国家专利优秀奖, , 国家级, 2013
（3） 2012年度发展中国家科学院农业奖, , 其他, 2012

专利成果（ 1 ） 用于敲除人 BTF 基因的sgRNA 序列及其敲除方法, 2015, 第 4 作者, 专利号: 5.5


出版信息
发表论文（1）One thousand plant transcriptomes and phylogenomics of green plants,Nature,2019-10,第12作者
（2）Evolution of Complex Thallus Alga: Genome Sequencing of Saccharina japonica,Frontiers in Genetics,2019-05,第11作者
（3）Microfluidics-Based Enrichment and Whole-Genome Amplification Enable Strain-Level Resolution for Airway Metagenomics.,mSystems,2019-05,第7作者
（4）Rice Genomics: over the Past Two Decades and into the Future,Genomics Proteomics Bioinformatics,2019-02,第11作者
（5）实现“终极版”核苷酸测序仪的技术要素,遗传,2018-11,第1作者
（6）RGAAT: A Reference-based Genome Assembly and Annotation Tool for New Genomes and Upgrade of Known Genomes,Genomics Proteomics Bioinformatics,2018-11,第11作者
（7）Genome-wide definition of selective sweeps reveals molecular evidence of trait-driven domestication among elite goat (Capra species) breeds for the production of dairy, cashmere, and meat,GigaScience,2018,第11作者
（8）The Bacterial RNA Ligase RtcB Accelerates the Repair Process of Fragmented rRNA upon Releasing the Antibiotic Stress,Science China-Life Sciences,2018,第11作者
（9）On the core bacterial flora of Ixodes persulcatus,Plos One,2017,第11作者
（10）Discovery of susceptibility loci associated with tuberculosis in Han Chinese,Hum Mol Genet,2017,第10作者
（11）MicroRNA Expression in Multistage Date Fruit Development,Methods Mol Biol,2017,第3作者
（12）identification of sequence variant associated with splicing event using RNA-seq data,BMC Bioinformatics,2017,第11作者
（13）The rubber tree genome reveals new insights into rubber production and species adaptation,Nature Plants,2016,第11作者
（14）MTD: a mammalian transcriptomic database to explore gene expression and regulation,Briefings in Bioinformatics,2016,第11作者
（15）Complete Sequence and Analysis of Coconut Palm (Cocos nucifera) Mitochondrial Genome,PLOS ONE,2016,第11作者
（16）Precision Medicine: What Challenges Are We Facing?,Genomics Proteomics & Bioinformatics,2016,第11作者
（17）Plastid-LCGbase: a collection of evolutionarily conserved plastid-associated gene pairs,Nucleic Acids Research,2015,第11作者
（18）KGCAK: a K-mer based database for genome-wide phylogeny and complexity evaluation,Biology Direct,2015,第11作者
（19）LCGserver: A Webserver for Exploring Evolutionary Trajectory of Gene Orders in a Large Number of Genomes,OMICS,2015,第11作者
（20）Profiling microRNA expression during multi-staged date palm (Phoenix dactylifera L.) fruit development,Genomics,2015,第11作者
（21）A Transcriptomic Study of the Red Palm Weevil (Rhynchophorus ferrugineus) Embryogenesis,Insect Science,2015,第11作者
（22）Heteroresistance at the single-cell level: adapting to antibiotic stress through a population-based strategy and growth-controlled interphenotypic coordination,mBio,2014,第11作者
（23）Genome sequence and genetic diversity of the common carp, Cyprinus carpio,Nature Genetics,2014,第11作者
（24）Genomic signatures of near-extinction and rebirth of the crested ibis and other endangered bird species,Genome Biology,2014,第11作者
（25）The quest for a unified view of bacterial land colonization,The ISME Journal,2014,第11作者
（26）Flexibility and Symmetry of Prokaryotic Genome Rearrangement Reveal Lineage-Associated Core-Gene-Defined Genome Organizational Frameworks,MBIO,2014,第11作者
（27）The Rice Genome Knowledgebase (RGKbase): an annotation database for rice comparative genomics and evolutionary biology,Nucleic Acids Research,2013,第11作者
（28）Genome sequence of the date palm Phoenix dactylifera L.,NATURE COMMUNICATIONS,2013,第11作者
（29）Functional networking of human divergently paired genes (DPGs),PLoS One,2013,第11作者
（30）Improved picoliter-sized micro-reactors for high-throughput biological analysis,Sci China Life Sci.,2013,第11作者
（31）The intestinal metagenome of red palm weevil (Rhynchophorus ferrugineus),Environ Microbiol. ,2013,第11作者
（32）Systematic analysis of intron size parameters in diverse lineages,Sci China Life Sci.,2013,第11作者
（33）Expression profiling of abundant genes in pulmonary and cardiac muscle tissues of Tibetan Antelope (Pantholops hodgsonii),Gene,2013,第11作者
（34）Mitochondrial genome sequences of Artemia tibetiana and A. urmiana: assessing molecular changes for high plateau adaptation,Sci China Life Sci.,2013,第11作者
（35）Identification of Human HK Genes and Gene Expression Regulation Study in Cancer from Transcriptomics Data Analysis,PLoS One,2013,第11作者
（36）Complete genome sequence of methicillin-sensitive Staphylococcus aureus containing a heterogeneic staphylococcal cassette chromosome element,Sci China Life Sci.,2013,第11作者
（37）Transcriptome profiling of the developing postnatal mouse testis using next-generation sequencing,Sci China Life Sci.,2013,第11作者
（38）A Large-scale Gene Discovery for the Red Palm Weevil Rhynchophorus ferrugineus (Coleoptera: Curculionidae),Insect Sci.,2013,第11作者
（39）Replication-Associated Mutational Pressure (RMP) Governs Strand-Biased Compositional Asymmetry (SCA) and Gene Organization in Animal Mitochondrial Genomes,current genomics,2012,第11作者
（40）A Comparative Transcriptomic Analysis of Uveal Melanoma and Normal Uveal Melanocyte,plos one,2011,第11作者
（41）Nonsynonymous substitution rate (Ka) is a relatively consistent parameter for defining fastevolving and slow-evolving protein-coding genes,Biology Direct,2011,第11作者
（42）On the Origin of Tibetans and Their Genetic Basis in Adapting High-Altitude Environments,plos one,2011,第11作者
（43）Both Size and GC-Content of Minimal Introns Are Selected in Human Populations,plos one,2011,第11作者
（44）Diverse LEA (late embryogenesis abundant) and LEA-like genes and their responses to hypersaline stress in post-diapause embryonic development of Artemia franciscana,Comparative Biochemistry and Physiology, Part B,2011,第11作者
（45）Coevolution study of mitochondria respiratory chain proteins:Toward the understanding of proteineprotein interaction,Journal of Genetics and Genomics,2011,第11作者
（46）The Disequilibrium of Nucleosomes Distribution along Chromosomes Plays a Functional and Evolutionarily Role in Regulating Gene Expression,plos one,2011,第11作者
（47）An Integrated Analysis of miRNA and mRNA Expressions in Non-Small Cell Lung Cancers,plos one,2011,第11作者
（48）An integrated analysis of lineage-specific small proteins across eight eukaryotes reveals functional and evolutionary significance,Progress in Biochemistry and Biophysics,2011,第11作者
（49）Bar-Coded Pyrosequencing Reveals the Bacterial Community during Microcystis water Bloom in Guanting Reservoir,Beijing,Procedia Engineering,2011,第11作者
（50）Comparative analysis of mitochondrial genomes between a wheat K-type cytoplasmic male sterility (CMS) line and its maintainer line,BMC genomics,2011,第11作者
（51）An efficient procedure for plant organellar genome assembly, based on whole genome data from the 454 GS FLX sequencing platform,PLANT METHODS,2011,第11作者
（52）Involvement of the GP63 protease in infection of Trichomonas vaginalis,Parasitol res,2011,第11作者
（53）Transposable-Element Associated Small RNAs in Bombyx mori Genome,plos one,2011,第11作者

发表著作（ 1 ） 基因组学核心实验方法,GENOMICS:ESSENTIAL METHODS,科学出版社,2012-03,第1作者
（ 2 ） 第二代测序信息处理,Next-Generation DNA Sequencing Informatics,科学出版社,2014-06,第3作者
（ 3 ） 基因组科学的甲子“羽化”之路——从人类基因组测序到精准医学,Mapping and Sequencing the Human Genome Toward Precision Medicine,科学出版社,2016-03,第1作者
（ 4 ） 基因组学与精准医学,Genomics and Precision Medicine,上海交通大学,2017-12,第1作者


科研活动
科研项目（ 1 ） 小型猪和小鼠等医学实验哺乳动物模型建立与基础数据集成, 主持,国家级,2011-01--2015-08
（ 2 ） 藏彝走廊世居群体遗传多样性调查, 参与,国家级,2013-01--2016-12
（ 3 ） 猪脂肪沉积等优质高产分子模块解析, 参与,部委级,2013-08--2017-12
（ 4 ） 个体化医学检测的规范化、标准化研究及应用推广, 主持,国家级,2014-06--2016-12
（ 5 ） 顽固群（persister）休眠细胞形成机制的单细胞水平研究, 主持,国家级,2015-01--2018-12
（ 6 ） 基于焦磷酸微纳电化学传感器阵列的基因组测序系统, 主持,部委级,2014-07--2016-06
（ 7 ） 细菌中环状RNA的合成机制及其在对抗抗生素压力中的作用, 主持,国家级,2017-01--2020-12
（ 8 ） 单分子操纵石墨烯纳米孔DNA测序仪, 主持,部委级,2016-01--2017-12
（ 9 ） 高速纳米孔核苷酸序列分析仪, 主持,部委级,2016-01--2017-12

参与会议（1）Cellular heterogeneity of cancers and resolutions of our technologies2017-11-03
（2）Precision Medicine in China2017“中国-东南亚国家联盟（Sino-ASEAN）”精准医学会议2017-06-17
（3）Analysis of worldwide population structure of species Escherichia coil reveals two major subspecies2017美国微生物学会年会2017-06-01
（4）Lineage-associated Variations of Core Genomes Restrict Horizontal Gene Transfer and Species Divergence of Eubacterial Taxa于军2015-10-25
（5）Genome Structures of Major Lineages2013国际基因组学大会Jun Yu2013-10-28
（6）Evolutionary Cell Biology: Minimal Intron-Containing(MIC) Genes and Beyond国际基因组学大会于军2011-11-23
（7）Understanding Cellular Processes Based on DNA Variation Data新一代测序亚洲大会于军2011-10-02


合作情况
项目协作单位

指导学生