基本信息
严冬男博导中国科学院分子植物科学卓越创新中心（植物生理生态研究所）
电子邮件： yandong@sibs.ac.cn
通信地址： 上海市枫林路300号
邮政编码：
部门/实验室：植生生态所
研究领域

招生信息
招生专业071010-生物化学与分子生物学

招生方向昆虫发育信号途径


教育背景2002-09--2009-06美国辛辛那提大学博士
1996-09--2000-07南京大学学士

学历
学位

工作经历
工作简历2016-08~现在,上海植物生理生态研究所,研究员
2010-06~2016-07,美国哈佛大学医学院,博士后

社会兼职

教授课程

专利与奖励
奖励信息
专利成果

出版信息
发表论文（1）Xio is a novel component of the Drosophila sex determination pathway and RNA N6-methyladenosine methyltransferase complex,PNAS,2018,通讯作者
（2）The m6A pathway facilitates sex determination in Drosophila,Nature Communications,2017,其他（合作组作者）
（3）Spenito is required for sex determination in Drosophila melanogaster,PNAS,2015,第1作者
（4）Histone H1-Mediated Epigenetic Regulation Controls Germline Stem Cell Self-Renewal by Modulating the Acetylation of H4 Lysine 16,Nature Communications,2015,其他（合作组作者）
（5）The Transgenic RNAi Project at Harvard Medical School: Resources and Validation,Genetics,2015,其他（合作组作者）
（6）Genome-Wide RNAi Screen Identifies Networks Involved in Intestinal Stem Cell Regulation in Drosophila,Cell Reports,2015,第6作者
（7）A sharp end to sugary Wingless travels,The Journal of Cell Biology,2014,第2作者
（8）A regulatory network of Drosophila germline stem cell self-renewal,Developmental Cell,2014,第1作者
（9）Depleting gene activities in early Drosophila embryos with the “maternal-Gal4-shRNA” system,Genetics,2013,第2作者
（10）Proteomic and functional genomic landscape of receptor tyrosine kinase and Ras/ERK signaling,Science Signaling,2011,第4作者
（11）The cell-surface proteins Dally-like and Ihog differentially regulate Hedgehog signaling strength and range during development,Development,2010,第1作者
（12）The core protein of glypican Dally-like determines its biphasic activity in Wingless morphogen signaling,Developmental Cell,2009,第1作者
（13）Opposing roles for glypicans in Hedgehog signalling,Nature Cell Biology,2008,第1作者
（14）Drosophila glypican Dally-like acts in FGF-receiving cells to modulate FGF signaling during tracheal morphogenesis,Developmental Biology,2007,第1作者
（15）Drosophila Glypicans Dally and Dally-like shape the extracellular Wingless morphogen gradient in the wing disc,Development,2005,第2作者
（16）Drosophila Dpp morphogen movement is independent of dynamin-mediated endocytosis and is controlled by glypican members of heparan sulfate proteoglycans,Cell,2004,第3作者
（17）Mutation of a lysine residue in a homeodomain generates dominant negative thyroid transcription factor 1,Biochemistry,2004,第2作者
（18）Peroxisome proliferator-activated receptor gamma and ligands inhibit surfactant protein B gene expression in the lung,The Journal of Biological Chemistry,2003,第2作者
（19）An enhancer region determines hSP-B gene expression in bronchiolar and ATII epithelial cells in transgenic mice,American Journal of Physiology Lung Cellular and Molecular Physiology,2003,第4作者

发表著作（1）Generating and Interpretation of Morphogen Gradients （Shaping morphogen gradient by proteoglycans.）,Cold Spring Harbor Laboratory Press,2010-03,第1作者


科研活动
参与会议

合作情况
项目协作单位