基本信息
王清男硕导中国科学院烟台海岸带研究所
电子邮件： qingwang@yic.ac.cn
通信地址： 山东省烟台市莱山区春晖路17号
邮政编码：

研究领域

招生信息
招生专业070703-海洋生物学

招生方向生态毒理学
逆境适应机制
海洋牧场


教育背景2007-09--2010-06中国科学院海洋研究所博士
2004-09--2007-06中国科学院海洋研究所硕士
2000-09--2004-06中国海洋大学学士

学历
学位

工作经历
工作简历2014-03~现在,中国科学院烟台海岸带研究所,副研究员
2010-06~2014-03,中国科学院烟台海岸带研究所,助理研究员
2007-09~2010-06,中国科学院海洋研究所,博士
2004-09~2007-06,中国科学院海洋研究所,硕士
2000-09~2004-06,中国海洋大学,学士

社会兼职

教授课程生态毒理学概论与研究进展


专利与奖励
奖励信息（1） 渤海典型污染物生态毒理效应与分子生物标志物研究, 二等奖, 市地级, 2018
（2） 海洋生态环境大数据集成及智慧平台的应用示范, 二等奖, 市地级, 2018
（3） 现代海洋牧场构建技术创新与集成应用, , 院级, 2017

专利成果（ 1 ） 紫贻贝G型溶菌酶基因及其重组蛋白和应用, 2014, 第 1 作者, 专利号: ZL8.X


出版信息
发表论文（1）Two macrophage migration inhibitory factors (MIFs) from the clam Ruditapes philippinarum: Molecular characterization, localization and enzymatic activities.,Fish & Shellfish immunology,2018,第11作者
（2）Microplastic pollution in sediments from the Bohai Sea and the Yellow Sea, China.,Science of The Total Environment,2018,第11作者
（3）CO2-induced ocean acidification impairs the immune function of the Pacific oyster against Vibrio splendidus challenge: An integrated study from a cellular and proteomic perspective,Science of The Total Environment,2018,第2作者
（4）Seawater acidification aggravated cadmium toxicity in the oyster Crassostrea gigas: Metal bioaccumulation, subcellular distribution and multiple physiological responses.,Science of The Total Environment,2018,第3作者
（5）A defensin-like antimicrobial peptide from the manila clam Ruditapes philippinarum: Investigation of the antibacterial activities and mode of action.,Fish & shellfish immunology,2018,第3作者
（6）Digital gene expression analysis in the gills of Ruditapes philippinarum exposed to short-and long-term exposures of ammonia nitrogen.,Aquatic Toxicology,2018,第5作者
（7）Molecular characterization, expression and antimicrobial activities of two c-type lysozymes from manila clam Venerupis philippinarum.,Developmental & Comparative Immunology,2017,第2作者
（8）Molecular characterization, expression and functional analysis of two Kazal-type serine protease inhibitors from Venerupis philippinarum.,Fish & shellfish immunology,2017,第3作者
（9）Individual and combined toxicities of benzo[a]pyrene and 2,2′,4,4′-Tetrabromodiphenyl Ether on early life stages of the Pacific oyster, Crassostrea gigas.,Bulletin of Environmental Contamination and Toxicology,2017,第11作者
（10）Combined toxicity of cadmium and lead on early life stages of the Pacific oyster, Crassostrea gigas.,Invertebrate Survival Journal,2017,第11作者
（11）Molecular characterization and antibacterial activity of a phage-type lysozyme from the Manila clam, Ruditapes philippinarum.,Fish & shellfish immunology,2017,第2作者
（12）Understanding regulation of microRNAs on intestine regeneration in the sea cucumber Apostichopus japonicus using high-throughput sequencing.,Comparative Biochemistry and Physiology Part D,2017,第6作者
（13）Effects of ocean acidification on immune responses of the Pacific oyster Crassostrea gigas,Fish & Shellfish immunology,2016,第1作者
（14）Impact of metal pollution on shrimp Crangon affinis by NMR-based metabolomics,Marine Pollution Bulletin,2016,第3作者
（15）An integrative biomarker approach to assess the environmental stress in the north coast of Shandong Peninsula using native oysters, Crassostrea gigas.,Marine Pollution Bulletin,2016,第3作者
（16）An integrated proteomic and metabolomics study on the gender-specific responses of mussels Mytilus galloprovincialis to tetrabromobisphenol A (TBBPA),Chemosphere,2016,第3作者
（17）Molecular diversity and evolution of defensins in the Manila clam Ruditapes philippinarum,Fish & Shellfish immunology,2015,第1作者
（18）Proteomic and metabolomic responses of Pacific oyster Crassostrea gigas to elevated pCO2 exposure,Journal of Proteomics,2015,第2作者
（19）A metabolomic investigation of the effects of metal pollution in oysters Crassostrea hongkongensis,Marine Pollution Bulletin,2015,第2作者
（20）Combined metabolome and proteome analysis of the mantle tissue from Pacific oyster Crassostrea gigas exposed to elevated pCO2,Comparative Biochemistry and Physiology, Part D,2015,第2作者
（21）A defensin from clam Venerupis philippinarum: Molecular characterization, localization, antibacterial activity, and mechanism of action,Developmental and Comparative Immunology,2015,第3作者
（22）Molecular characterization of two glutathione peroxidase genes in Mytilus alloprovincialis and their transcriptional responses to sub-chronic arsenate and cadmium exposure,Invertebrate Survival Journal,2014,第1作者
（23）Identification and mRNA expression of two17-hydroxysteroid dehydrogenase genes in the marine mussel Mytilus galloprovincialis following exposure to endocrine disrupting chemicals,Environmental Toxicology and Pharmacology,2014,第2作者
（24）A novel C-type lysozyme from Mytilus galloprovincialis: Insight into innate immunity and molecular evolution of invertebrate C-type lysozymes,PLoS one,2013,第1作者
（25）Molecular characterization of a manganese superoxide dismutase and copper/zinc superoxide dismutase from the mussel Mytilus galloprovincialis,Fish & Shellfish immunology,2013,第1作者
（26）Molecular cloning, characterization and expression profiles of thioredoxin 1 and thioredoxin 2 genes in Mytilus galloprovincialis,Chinese Journal of Oceanology and Limnology,2013,第1作者
（27）A metabolomics investigation on arsenic-induced toxicological effects in the clam Ruditapes philippinarum under different salinities,EcotoxicologyandEnvironmentalSafety,2013,第3作者
（28）Identification of glutaredoxin 1 and glutaredoxin 2 genes from Venerupis philippinarum and their responses to benzo[a]pyrene and bacterial challenge,Fish & Shellfish Immunology,2012,第11作者
（29）Toxic effects of benzo[a]pyrene (Bap) and Aroclor1254 on embryogenesis, larval growth, survival and metamorphosis of the bivalve Meretrix meretrix,Ecotoxicology,2012,第1作者
（30）Two goose-type lysozymes in Mytilus galloprovincialis: possible function diversification and adaptive evolution,PLoS One,2012,第1作者
（31）Responses of thioredoxin 1 and thioredoxin-related protein 14 mRNAs to cadmium and copper stresses in Venerupis philippinarum,Comparative Biochemistry and Physiology, Part C,2011,第1作者
（32）Involvement of phosphatidylinositol signaling pathway during serotonin-induced oocyte maturation of Mercenaria mercenaria,Chinese journal of oceanology and limnology,2011,第1作者
（33）Analysis of metallotionein expression and antioxidant enzymes activities in clam Meretrix meretrix larvae under sublethal cadmium exposure,Aquatic toxicology,2010,第1作者
（34）Toxicity of lead, cadmium and mercury on embryogenesis, survival, growth and metamorphosis of Meretrix meretrix larvae,Ecotoxicology,2009,第1作者
（35）Involvment of Ca2+ signaling pathway during oocyte maturation of the northern quahog Mercenaria mercenaria,Journal of Shellfish Research,2009,第2作者
（36）cAMP信号通路在5-羟色胺诱导硬壳蛤卵母细胞成熟过程中的作用,高技术通讯,2008,第1作者

发表著作

科研活动
科研项目（ 1 ） 莱州湾塑料微粒（microplastics）的污染现状及其毒性效应研究, 主持,国家级,2016-01--2019-12
（ 2 ） 微塑料对海洋生物的毒性效应, 主持,部委级,2016-01--2019-12
（ 3 ） 烟台牟平海洋牧场生态安全和环境保障, 参与,部委级,2015-01--2018-12
（ 4 ） 陆基海洋生态系统模拟装备的研制, 主持,部委级,2018-01--2019-12
（ 5 ） 海岸带生态农牧场关键技术集成与示范, 主持,部委级,2018-01--2019-06
（ 6 ） 中集渔业本底调查项目, 主持,院级,2018-01--2018-12
（ 7 ） 高效海洋生态牧场关键技术集成与示范, 主持,部委级,2017-01--2018-06

参与会议

合作情况
项目协作单位

指导学生