基本信息
青琳森男硕导中国科学院成都生物研究所
电子邮件： qingls@cib.ac.cn
通信地址： 四川省成都市人民南路四段9号 中科院成都生物所
邮政编码：

招生信息
招生专业100704-药物分析学

招生方向天然活性成分分析
天然新药开发


教育背景2008-09--2011-06中国科学院成都生物研究所博士
2003-09--2006-06四川大学华西药学院硕士
1999-09--2003-06华西医科大学药学院学士


工作经历
工作简历2013-07~现在,中国科学院成都生物研究所,副研究员
2012-08~2012-12,美国杰克逊州立大学化学系,研究助理
2011-07~2013-06,中国科学院成都生物研究所,博士后
2006-07~2008-08,成都地奥制药集团,新药研发工程师
2004-06~2005-05,香港浸会大学中医药学院,访问


专利与奖励
专利成果（ 1 ） 一种表面键合黄芩苷磁性纳米粒子及其制备方法和用途, 发明, 2013, 第 1 作者, 专利号: ZL 2.7
（ 2 ） 一种黄芪甲苷衍生物及其制备方法和应用, 发明, 2018, 第 1 作者, 专利号: ZL 7
（ 3 ） 一种基于玻璃毛细管的牛血清白蛋白检测探针及其制备方法和应用, 发明, 2017, 第 1 作者, 专利号: CN 6.9
（ 4 ） 山菅兰活性提取物及其制备方法和应用, 发明, 2019, 第 1 作者, 专利号: ZL 9.8
（ 5 ） 一种基于功能化纳米二氧化硅的临床药物分析方法, 发明, 2019, 第 1 作者, 专利号: CN 7
（ 6 ） 黄芪苷酸及其衍生物在制备抗血栓药物中的应用, 发明, 2018, 第 1 作者, 专利号: CN 4
（ 7 ） 一种牛血清白蛋白检测探针及其制备方法和应用, 发明, 2018, 第 1 作者, 专利号: ZL 3
（ 8 ） 一种伏立康唑的合成方法, 发明, 2019, 第 1 作者, 专利号: ZL 3


出版信息
发表论文（1）A new strategy for the preparation of antibody against natural glycoside: With astragaloside IV as an example,Fitoterapia,2020-01,通讯作者
（2）A feasible image-based colorimetric assay using a smartphone RGB camera for point-of-care monitoring of diabetes,Talanta,2020-01,通讯作者
（3）Colorimetric determination of the early biomarker hypoxia-inducible factor-1 alpha (HIF-1α) in circulating exosomes by using a gold seed-coated with aptamer-functionalized Au@Au core-shell peroxidase mimic,Microchimica Acta,2020-01,通讯作者
（4）Competitive protein binding assay of naproxen by human serum albumin functionalized silicon dioxide nanoparticles,Molecules,2019-09,通讯作者
（5）Determination of flavonoid glycosides by UPLC-MS to authenticate commercial lemonade,Molecules,2019-06,通讯作者
（6）Quality evaluation of Tricholoma matsutake based on the nucleic acid compounds by UPLC-TOF/MS and UPLC-QqQ/MS,Molecules,2019,通讯作者
（7）UPLC-QqQ/MS combined with similarity assessment of 17 nucleic acid constituents in 147 edible fungi from Sichuan Basin, China,Food Research International,2019,通讯作者
（8）Pharmacokinetics comparison, intestinal absorption and acute toxicity assessment of a novel water-soluble astragaloside IV derivative (astragalosidic acid, LS-102),European Journal of Drug Metabolism and Pharmacokinetics,2019,第1作者
（9）Determination of a astragaloside IV derivative LS-102 in plasma by ultra-performance liquid chromatography-tandem mass spectrometry in dog plasma and its application in a pharmacokinetic study,Phytomedicine,2019,通讯作者
（10）Optimization of vortex-assisted dispersive liquid-liquid microextraction for the simultaneous quantitation of eleven non-anthocyanin polyphenols in commercial blueberry using the multi-objective response surface methodology and desirability function approach,Molecules,2018,通讯作者
（11）A efficient method to identify cardioprotective components of Astragali Radix using a combination of molecularly imprinted polymers-based knockout extract and activity evaluation,Journal of Chromatography A,2018,通讯作者
（12）Neutral loss scan - based strategy for integrated identification of amorfrutin derivatives, new peroxisome proliferator-activated receptor gamma agonists, from Amorpha Fruticosa by UPLC-QqQ-MS/MS and UPLC-Q-TOF-MS,Journal of The American Society for Mass Spectrometry,2018,通讯作者
（13）Astragalosidic acid: a new water-soluble derivative of astragaloside IV prepared using remarkably simple TEMPO-mediated oxidation,Molecules,2017,第1作者
（14）A simple nano-SiO2-based ELISA method for residue detection of 2,4-dichlorophenoxyacetic acid in bean sprouts,Food Analytical Methods,2017,通讯作者
（15）An efficient direct competitive nano-ELISA for residual BSA determination in vaccines,Analytical and Bioanalytical Chemistry,2017,通讯作者
（16）Development of a nano-SiO2 based enzyme-linked ligand binding assay for the determination of ibuprofen in human urine,Talanta,2017,通讯作者
（17）Determination of contents of catechins in oolong teas by quantitative analysis of multi-components via a single marker (QAMS) method,Food Analytical Methods,2017,通讯作者

发表著作（1）彝药化学,民族出版社,2017-08,第2作者


科研活动
科研项目（ 1 ） 基于多靶标的微循环改善创新药物LS-102的临床前药效学研究, 主持,部委级,2018-08--2021-08
（ 2 ） 中国科学院“西部青年”（院内A类）项目, 主持,部委级,2019-01--2021-12
（ 3 ） 黄芪甲苷水溶性衍生物的成药性研究, 主持,省级,2019-01--2022-01