基本信息
牛忠伟男博导中国科学院理化技术研究所
电子邮件： niu@mail.ipc.ac.cn
通信地址： 北京市中关村北一条2号
邮政编码： 100190

研究领域

招生信息
招生专业070305-高分子化学与物理
080501-材料物理与化学

招生方向生物材料、自组装
功能高分子材料


教育背景2000-09--2003-07中国科学院化学研究所博士学位
1997-09--2000-04东北石油大学硕士学位
1993-09--1997-07东北石油大学本科 学士学位

学历
学位

工作经历
工作简历2009-11~现在,中国科学院理化技术研究所,研究员
2008-02~2009-11,美国南卡罗来纳大学,研究助理教授
2005-04~2008-02,美国南卡罗来纳大学,博士后
2004-04~2005-04,比利时鲁汶大学,博士后
2003-07~2004-03,北京交通大学,讲师
2000-09~2003-07,中国科学院化学研究所,博士学位
1997-09~2000-04,东北石油大学,硕士学位
1993-09~1997-07,东北石油大学,本科 学士学位

社会兼职

教授课程光功能材料化学（二）
光化学系列讲座


专利与奖励
奖励信息（1） 中国科学院优秀博士论文, 特等奖, 院级, 2004

专利成果（ 1 ） 一种具有取向生长结构细胞的材料的制备方法, 2012, 第 1 作者, 专利号: 0.4
（ 2 ） 一种表面改性的聚多巴胺纳米粒子Pickering乳液的制备方法, 2016, 第 1 作者, 专利号: 7.7
（ 3 ） 一种镧铁硅基室温磁制冷复合材料及制备方法, 2013, 第 2 作者, 专利号: 3.8
（ 4 ） 一种表面功能化的烟草花叶病毒纳米线复合材料的制备方法, 2015, 第 2 作者, 专利号: 2.5
（ 5 ） 一种碳基室温磁制冷复合材料及其制备方法, 2014, 第 2 作者, 专利号: 5.2


出版信息
发表论文（1）Single-Wavelength Excited Ratiometric Fluorescence pH Probe to Image Intracellular Trafficking of Tobacco Mosaic Virus,Chinese J. Polym. Sci.,2019-12,第11作者
（2）Membrane intercalation-enhanced photodynamic inactivation of bacteria by a metallacycle and TAT-decorated virus coat protein,Proc. Natl. Acad. Sci. USA,2019-11,第8作者
（3）Phenotype Regulation of Smooth Muscle Cells Through Facial Crystallization of Poly(ε-Caprolactone),Journal of Nanoscience and Nanotechnology,2019-03,第11作者
（4）Balancing antimicrobial activity with biological safety: bifunctional chitosan derivative for the repair of wounds with Gram-positive bacterial infections,J Mater Chem B,2018,第11作者
（5）Fluorous interaction induced self-assembly of tobacco mosaic virus coat protein for cisplatin delivery,Nanoscale,2018,第11作者
（6）Integration of Cell-Penetrating Peptides with Rod-like Bionanoparticles: Virus-Inspired Gene-Silencing Technology,Nano Lett,2018,第11作者
（7）Glyco-decorated tobacco mosaic virus as a vector for cisplatin delivery,J Mater Chem B,2017,第11作者
（8）Programming Self-Assembly of Tobacco Mosaic Virus Coat Proteins at Pickering Emulsion Interfaces for Nanorod-Constructed Capsules,ACS Appl Mater Interfaces,2017,第11作者
（9）Mussel-Inspired Polydopamine Coating on Tobacco Mosaic Virus: One-Dimensional Hybrid Nanofibers for Gold Nanoparticle Growth,Langmuir,2017,第11作者
（10）A perspective on general direction and challenges facing antimicrobial peptides,Chinese Chemical Letters,2017,第11作者
（11）烟草花叶病毒的特定位点改性及应用,影 像 科 学 与 光 化 学,2017,第11作者
（12）One-Pot Green Synthesis of Nitrogen-Doped Carbon Quantum Dots for Cell Nucleus Labeling and Copper(II) Detection,Chem Asian J,2017,第11作者
（13）Filamentous Virus Oriented Pyrene Excimer Emission and Its Efficient Energy Transfer,Journal of Photochemistry & Photobiology, A: Chemistry,2017,第11作者
（14）Hierarchical Self-Assembly of Responsive Organoplatinum(II) Metallacycle?TMV Complexes with Turn-On Fluorescence,J Am Chem Soc,2016,第11作者
（15）Integrating a DNA Strand Displacement Reaction with a Whispering Gallery Mode Sensor for Label-Free Mercury (II) Ion Detection,Sensors,2016,第3作者
（16）Into the polymer brush regime through the ‘‘grafting-to’’ method: densely polymer-grafted rodlike viruses with an unusual nematic liquid crystal behavior,Soft Matter,2016,第11作者
（17）Size Dependent Cellular Uptake of Rod-like Bionanoparticles with Different Aspect Ratios,Sci Rep,2016,第11作者
（18）Tobacco Mosaic Virus-Based 1D Nanorod-Drug Carrier via the Integrin-Mediated Endocytosis Pathway,ACS Appl Mater Interfaces,2016,第11作者
（19）Multifunctional self-assembled polymeric nanoprobes for FRET-based ratiometric detection of mitochondrial H2O2 in living cells,Chem Commun,2015,第11作者
（20）Probing the endocytic pathways of the filamentous bacteriophage in live cells using ratiometric pH fluorescent indicator,Adv Healthc Mater,2015,第11作者
（21）Confined chromophores in tobacco mosaic virus to mimic green fluorescent protein,Chem Commun,2015,第11作者
（22）Temperature responsive 3D structure of rod-like bionanoparticles induced by depletion interaction,Chinese Journal of Polymer Science,2014,第11作者
（23）Polymeric supra-amphiphiles based on terminal group electrostatic interactions: fabrication of micelles with modifiable surfaces,Langmuir,2014,第11作者
（24）Electrospun tubular scaffold with circumferentially aligned nanofibers for regulating smooth muscle cell growth,ACS Appl Mater Interfaces,2014,第11作者
（25）Expanding the genetic code for site-specific labelling of tobacco mosaic virus coat protein and building biotin-functionalized virus-like particles,Chem Commun,2014,第11作者
（26）Hetero-epitaxy of anisotropic polycaprolactone films for the guidance of smooth muscle cell growth,Chem Commun,2013,第11作者
（27）Enhanced orientation of PEO polymer chains induced by nanoclays in electrospun PEO/clay composite nanofibers,Colloid and Polymer Science,2013,第11作者
（28）Biobehavior in normal and tumor-bearing mice of tobacco mosaic virus,Biomacromolecules,2013,第11作者
（29）Edge-modified amphiphilic Laponite nano-discs for stabilizing Pickering emulsions,J Colloid Interface Sci,2013,第11作者
（30）Nonionic block copolymers assemble on the surface of protein bionanoparticle,Langmuir,2012,第11作者
（31）Natural supramolecular building blocks: from virus coat proteins to viral nanoparticles,Chem Soc Rev,2012,第11作者
（32）Electrospinning fabrication, structural and mechanical characterization of rod-like virus-based composite nanofibers,J. Mater. Chem., 2011, 21, 8550,2011,第4作者
（33）Self-Assembly of Virus Particles on Flat Surfaces via Controlled Evaporation,Langmiur 2011, 27, 1398,2011,第11作者
（34）Self-assembly of viral particles,Current Opinion in Colloid and Interface Science,2011,第2作者
（35）Polymer-virus core-shell structures prepared via co-assembly and template synthesis methods,Science in China B: Chemistry, 2010, 53, 71,2010,第2作者
（36）Synthesis of nano/micro structure at interfaces,Angew Chem Int Ed 2010, 49, 10052,2010,第1作者
（37）Self-assembly of rod-like bionanoparticles in capillary tube,Angew Chem Int Ed 2010, 49, 868,2010,第4作者
（38）Tobacco mosaic virus based thin film sensor for detection of volatile organic compounds,J. Mater. Chem., 2010, 20, 5715,2010,第11作者
（39）Controlled assembly of protein in glass capillary,Langmuir, 2010, 26, 12803,2010,第4作者
（40）Pulling genetic RNA out of tobacco mosaic virus using single-molecule force spectroscopy,J. Am. Chem. Soc., 2010, 132, 11036,2010,第11作者
（41）Chemical modification of M13 bacteriophage and its application in cancer cell imaging,Bioconjugate Chem. 2010, 21, 1369,2010,第11作者
（42）Tobacco mosaic virus templated synthesis of one dimensional inorganic/polymer hybrid fibres,J. Mater. Chem. 2009, 21, 2841,2009,第11作者
（43）Synthesis and characterization of bionanoparticle-silica composites and mesoporous silica with large pores,Nano Research, 2009, 2, 474,2009,第1作者
（44）Structure and Interaction in 2D Assemblies of Tobacco Mosaic Viruses,Soft Matter, 2009, 5, 4951,2009,第11作者
（45）The bioconjugation of bionanoparticles,Nano Research, 2009, 2, 349,2009,第2作者
（46）Self-assembly of tobacco mosaic virus at oil/water interface,Langmuir, 2009, 25, 4979,2009,第2作者
（47）Soft raspberry-like colloids assembled from icosahedral plant virus and polymer,Chem. Mater. 2009, 21, 1046,2009,第3作者
（48）Oriented cells growth on self-assembled bacteriophage M13 thin films,Chem. Commun. 2008, 5185,2008,第11作者
（49）Bacteriophage M13 as scaffold for preparing conductive polymeric composite fibers,Nano Research, 2008, 1, 235,2008,第1作者
（50）Core-Shell biocomposite from hierarchical assembly of bionanoparticle and polymer,Small 2008, 4, 1624,2008,第2作者
（51）Layer-by-layer assembly of viral capsid for cellular adhesion,Acta Biomaterials 2008, 4, 838-843,2008,第3作者
（52）Nanomechanical characterization of polyaniline coated tobacco mosaic virus nanotubes,J Biomed Mater Res, 2008, 87A, 8,2008,第2作者
（53）Biological templated synthesis of water-soluble conductive polymeric nanowires,Nano Lett. 2007, 7, 3729,2007,第1作者
（54）Assembly of tobacco mosaic virus into fibrous and macroscopic bundled arrays by aniline polymerization on its surface,Langmuir 2007, 23, 6719,2007,第1作者
（55）Study and characterization of tobacco mosaic virus head-to-tail assembly assisted by aniline polymerization,Chem. Commun. 2006, 3019,2006,第1作者

发表著作（ 1 ） 细胞和生物分子的识别,Cellular and Biomolecular Recognition,Wiley-VCH, Weinheim,2009-06,第1作者
Viral nanoparticles for diagnostic and therapeutic applications. Nanoparticles for Biotherapeutic Delivery,Future science group,2015-01,第2作者
Self-assembly of rod-like bionanoparticles at interfaces and in solution,Humana Press,2018-09,第2作者


科研活动
科研项目（ 1 ） 生物纳米粒子模板合成一维Janus结构, 主持,国家级,2011-01--2013-12
（ 2 ） 基于生物纳米粒子和嵌段共聚物的可控组装及其生物医用, 主持,国家级,2011-01--2013-12
（ 3 ） 功能高分子材料的生物医用研究, 主持,部委级,2011-01--2012-12
（ 4 ） 内壁具有规整纳微取向结构的聚合物微管的制备及其对血 管平滑肌细胞行为的影响, 主持,国家级,2012-01--2015-12
（ 5 ） 烟草花叶病毒蛋白-高分子生物杂合嵌段共聚物的构筑及其组装, 主持,国家级,2015-01--2018-12
（ 6 ） 重大疾病相关的若干重要难检活性小分子细胞内纳米传感研究, 参与,国家级,2013-01--2017-08
（ 7 ） 基于生物材料构建的微环境诱导多种损伤组织同步修复再生的基础科学问题与关键技术研究, 参与,国家级,2017-07--2020-12
（ 8 ） 植入材料多物理特性高通量耦合设计计算与构建, 主持,国家级,2018-09--2021-06

参与会议（1）Rod-like Plant Virus: Functionalization, Self-Assembly and Bioapplications2016-03-13
（2）Rod-like virus: modification, self-assembly, cellular internalization mechanism and biobehavior in normal mice2015-05-09
（3）Self-assembly of bionanoparticles牛忠伟2010-10-30
（4）生物纳米粒子的可控组装中国化学会第27届学术年会牛忠伟2010-06-20


合作情况
项目协作单位

指导学生