基本信息
李洋男硕导中国科学院深圳先进技术研究院
电子邮件： yang.li@siat.ac.cn
通信地址： 中科院深圳医药所纳米中心
邮政编码：
部门/实验室：医药所
研究领域1） 癌症免疫学（肿瘤免疫治疗）
2） 纳米医学（纳米药物的肿瘤靶向与免疫治疗）
3） 免疫学（巨噬细胞，IL-1家族，炎症因子）
4） 纳米免疫安全性 （纳米毒理学）



招生信息
1） 免疫学,生物学
2） 纳米医学，纳米生物学
3） 化学（化学生物学）




招生专业071010-生物化学与分子生物学
0703J1-纳米科学与技术
100102-免疫学

招生方向纳米医学，纳米免疫安全性
癌症免疫，免疫检查点治疗
天然免疫系统，天然免疫记忆


教育背景2011-11--2014-10萨尔斯堡大学博士

学历
学位

工作经历
工作简历2016-09~2018-06,科罗拉多大学,博士后
2015-07~2016-08,堪萨斯纳米技术研发中心,博士后
2014-10~2014-12,意大利国家科学院,博士后
2011-10~2014-10,意大利国家研究院,玛丽居里研究员/博士

社会兼职

教授课程

专利与奖励
奖励信息（1） 国际纳米毒理学大会旅行奖, 一等奖, 专项, 2016
（2） 优秀自费留学生奖学金, 一等奖, 国家级, 2013
（3） 玛丽居里奖学金, 一等奖, 其他, 2011

专利成果

出版信息
发表论文（1）Modulation of the inflammatory tumor microenvironment - a new approach for photothermal-synergized cancer immunotherapy,Nanomedicine,2019,通讯作者
（2）Bacterial endotoxin (lipopolysaccharide) binds to the surface of gold nanoparticles, interferes with biocorona formation and induces human monocyte inflammatory activation,Nanotoxicology,2017,第1作者
（3）Endotoxin contamination in nanomaterials leads to the misinterpretation of immunosafety results,Frontiers in immunology,2017,第1作者
（4）An imbalance between IL-1 and IL-1Ra in human melanoma cells accounts for autoinflammation and contributes to tumor progression in metastatic melanoma,Journal of Investigative Dermatology,2017,第1作者
（5）Mechanisms of cell uptake, inflammatory potential and protein corona effects with gold nanoparticles,Nanomedicine,2016,第1作者
（6）Endotoxin contamination: a key element in the interpretation of nanosafety studies,Nanomedicine,2016,第1作者
（7）Assessing the Immunosafety of Engineered Nanoparticles with a Novel in Vitro Model Based on Human Primary Monocytes,ACS Applied Materials & Interfaces,2016,第1作者
（8）Optimising the use of commercial LAL assays for the analysis of endotoxin contamination in metal colloids and metal oxide nanoparticles,Nanotoxicology,2015,第1作者
（9）Uptake and bio-reactivity of polystyrene nanoparticles is affected by surface modifications, ageing and LPS adsorption: in vitro studies on neural tissue cells,Nanoscale,2015,第3作者
（10）Multiwall Carbon Nanotubes Mediate Macrophage Activation and Promote Pulmonary Fibrosis Through TGF-β/Smad Signaling Pathway,Small,2013,第4作者
（11）The contributions of metal impurities and tube structure to the toxicity of carbon nanotube materials,NPG Asia Materials,2012,第2作者
（12）Acute pulmonary and moderate cardiovascular responses of spontaneously hypertensive rats after exposure to single-wall carbon nanotubes,Nanotoxicology,2012,第7作者
（13）The triggering of apoptosis in macrophages by pristine graphene through the MAPK and TGF-beta signaling pathways,Biomaterials,2012,第1作者

发表著作

科研活动
科研项目（ 1 ） 纳米颗粒蛋白质晕(biocorona)对炎症小体激活和白介素1分泌的调控, 主持,国家级,2018-01--2020-12

参与会议（1）Autoinflammation from the imbalance of IL-1 over IL-1Ra contributes to tumor progression in metastatic melanomaYang Li2017-08-26
（2）An imbalance between IL-1 and IL-1Ra in human melanoma cells accounts for autoinflammation and contributes to tumor progression in metastatic melanomaYang Li2017-04-26
（3）Protein coronas affect the mechanisms of cell uptake and inflammatory effects of gold nanoparticles2016-10-26
（4）Cellular uptake mechanism of gold nanoparticles with three different surface coatings and protein corona effects on cell uptake in human epidermal keratinocytes2016-06-01
（5）Evaluating engineered nanoparticle immunosafety: effects on the course of the innate immune reaction of human primary monocytes in vitro2014-06-18
（6）Bacterial endotoxin binds to the surface of gold nanoparticles and triggers inflammation2014-04-23
（7）An in vitro model based on human primary monocytes for evaluating the effects of engineered nanoparticles on the course of an inflammatory defence reaction2014-04-23
（8）Assessing interference of nanoparticles with the inflammatory response by a novel in vitro model based on human primary monocytes2013-09-05
（9）Assessing immune toxicity of engineered nanoparticles: modulation of inflammation in a novel in vitro model based on human primary monocytesYang LI2013-08-22
（10）Human primary monocytes as reference cells for assessing interference of nanoparticles with the inflammatory defence reactionYang Li2013-02-27
（11）The triggering of apoptosis in macrophages by pristine graphene through the MAPK and TGF-beta signaling pathways2012-09-04
（12）The triggering of apoptosis in macrophages by pristine graphene through the MAPK and TGF-beta signaling pathways2012-02-27


合作情况
项目协作单位

指导学生