基本信息
胡春秀女硕导中国科学院大连化学物理研究所
电子邮件： hucx@dicp.ac.cn
通信地址： 大连市沙河口区中山路457号大连化物所生物技术部
邮政编码： 116023
部门/实验室：研究生部
研究领域

招生信息
招生专业070302-分析化学

招生方向基于色谱-质谱联用的代谢组学新技术、新方法的开发及应用


教育背景2006-05--2012-06荷兰莱顿大学 (Leiden University)生物科学博士学位
2005-09--2011-07中科院大连化物所分析化学博士学位
1999-09--2002-06四川大学物理化学硕士学位
1995-09--1999-06海南师范学院化学教育学士学位

学历
学位

工作经历
工作简历2014-07~现在,中科院大连化学物理研究所,副研究员
2011-07~2014-07,中科院大连化学物理研究所,助理研究员
2002-07~2005-07,中石化上海石油化工股份有限公司化工研究所,仪器分析助理工程师

社会兼职

教授课程

专利与奖励
奖励信息（1） 礼来亚洲优秀研究生论文奖二等奖, , 其他, 2012
（2） 中国科学院研究生院“三好学生标兵”, , 院级, 2011

专利成果（ 1 ） 一种基于液相色谱-质谱联用的高覆盖脂质组学分析方法, 发明, 2017, 第 3 作者, 专利号: 3.8


出版信息
发表论文（1）Plasma metabolomics profiling of maintenance hemodialysis based on capillary electrophoresis - time of flight mass spectrometry,Sci Rep,2017,通讯作者
（2）A lipidomics study reveals hepatic lipid signatures associating with deficiency of the LDL receptor in a rat model.,Biol Open,2016,第3作者
（3）Plasma Lipidomics Investigation of Hemodialysis Effects by Using Liquid Chromatography-Mass Spectrometry.,J Proteome Res,2016,第2作者
（4）Metabolic Profiling with Gas Chromatography-Mass Spectrometry and Capillary Electrophoresis-Mass Spectrometry Reveals the Carbon-Nitrogen Status of Tobacco Leaves Across Different Planting Areas.,J Proteome Res,2016,第2作者
（5）Mass Spectrometry-Based Lipidomics for Biomarker Research,General Methods in Biomarker Research and their,2015,第1作者
（6）Discovery and Validation of Plasma Biomarkers for Major Depressive Disorder Classification Based on Liquid Chromatography-Mass Spectrometry,J. Proteome Res.,2015,第5作者
（7）On-line stop-flow two-dimensional liquid chromatography–mass spectrometry method for the separation and identification of triterpenoid saponins from ginseng extract,Anal. Bioanal. Chem.,2015,第4作者
（8）Study of polar metabolites in tobacco from different geographical origins by using capillary electrophoresis–mass spectrometry,Metabolomics,2014,第2作者
（9）Lipid Profiling Reveals Different Therapeutic Effects of Metformin and Glipizide in Patients With Type 2 Diabetes and Coronary Artery Disease,Diabetes care,2014,第1作者
（10）Metabolomics and traditional Chinese medicine,Trend. Anal. Chem.,2014,第1作者
（11）Metabolomics Study of Hepatocellular Carcinoma: Discovery and Validation of Serum Potential Biomarkers by Using Capillary Electrophoresis-Mass Spectrometry,J. Proteome Res.,2014,第5作者
（12）Mass-spectrometry-based metabolomics analysis for foodomics,Trend. Anal. Chem.,2013,第1作者
（13）Large-scaled human serum sphingolipid profiling by using reversed-phase liquid chromatography coupled with dynamic multiple reaction monitoring of mass spectrometry: Method development and application in hepatocellular carcinoma,J. Chromatogr. A ,2013,第2作者
（14）Effect of Bisphenol A on Rat Metabolic Profiling Studied by Using Capillary Electrophoresis Time-of-Flight Mass Spectrometry,Environ. Sci. Technol.,2013,第3作者
（15）Serum lipid profiling of patients with chronic hepatitis B, cirrhosis, and hepatocellular carcinoma by ultra fast LC/IT-TOF MS,Electrophoresis,2013,第5作者
（16）液质联用代谢组学研究多氯联苯和二噁英对大鼠毒性作用,环境化学,2013,通讯作者
（17）Lipidomics reveals multiple pathway effects of a multi-components preparation on lipid biochemistry in ApoE*3Leiden.CETP mice,PLoS ONE,2012,第1作者
（18）Plasma and Liver Lipidomics Response to an Intervention of Rimonabant in ApoE*3Leiden.CETP Transgenic Mice,PLoS ONE,2011,第1作者
（19）Application of plasma lipidomics in studying the response of patients with essential hypertension to antihypertensive drug therapy,Mol. BioSyst.,2011,第1作者
（20）Linking biological activity with herbal constituents by systems biology-based approaches: effects of Panax ginsengin type 2 diabetic Goto-Kakizaki rats,Mol. BioSyst.,2011,第1作者
（21）超高效液相色谱飞行时间质谱快速分析人参根中的皂甙化合物,色谱,2011,第1作者
（22） Lipidomics analysis reveals efficent storage of hepatic triacylglycerides enriched in Unsaturated fatty acid after one bout of exercise in mice,PLoS ONE,2010,第1作者
（23）Analytical strategies in lipidomics and applications in disease biomarker discovery,J. Chromatogr., B. ,2009,第1作者
（24）RPLC-Ion-Trap-FTMS Method for Lipid Profiling of Plasma: Method Validation and Application to p53 Mutant Mouse Model,J. Proteome Res. ,2008,第1作者
（25）Screening and analysis of bioactive compounds in traditional Chinese medicines using cell extract and gas chromatography-mass spectrometry,J. Pharma. Biomed. Anal.,2007,第2作者

发表著作（1）系统生物学方法评价中药,Systems Biology for Evaluating System-based Medicine,Faculteit der Wiskunde en Natuurwetenschappen, Leiden University,2012-06,第1作者


科研活动
科研项目（ 1 ） 基于组学特征谱的2型糖尿病分子分型及分类体系的研究, 参与,国家级,2017-01--2019-12
（ 2 ） 转基因生物代谢组水平分子特征分析和鉴定技术研究, 参与,国家级,2016-01--2020-12

参与会议（1）PLASMA LIPID PROFLING STUDY OF HEMODIALYSIS PATIENTS BY LC-MS2015-09-21
（2）Metabolic Profiling Analysis of Tissues Based on CE-TOF/MS2013-05-12
（3）Lipidomics in Disease Biomarker DiscoveryChunxiu Hu, Guowang Xu2012-10-15
（4）Lipidomics in disease biomarker discovery: methods and applications2012-05-27
（5）脂质组学的LC-MS分析方法及其在疾病生物标志物研究中的应用全国生物医药色谱及相关技术学术交流会胡春秀2012-04-22
（6）DISEASE BIOMARKER DISCOVERY AND IDENTIFICATION BY USING MASS SPECTROMETRY BASED METABOLOMICS2011-10-12
（7）Linking biological activity with herbal constituents by systems biology-based approaches: effects of Panax ginseng intype 2 diabetic Goto-Kakizaki ratsChunxiu Hu, Heng Wei, Hongwei Kong, Jildau Bouwman, Theo H. Reijmers, Elwin R. Verheij, Thomas Hankemeier, Jan van der Greef, and Mei Wang*, Guowang Xu*2011-10-10


合作情况
项目协作单位

指导学生