基本信息
桂建芳男博导中国科学院院士&发展中国家院士 中国科学院水生生物研究所
电子邮件： jfgui@ihb.ac.cn
联系电话： 86-
邮政编码： 430072


研究领域鱼类发育遗传学与细胞工程学

招生信息
招生专业071007-遗传学
090801-水产养殖

招生方向发育生物学
鱼类遗传育种学


教育背景1992-08--1994-08美国加州大学圣迭戈校区细胞和分子医学系访问
1991-12--1995-06中国科学院水生生物研究所博士
1991-12--1992-08美国俄亥俄医学院访问
1982-01--1984-12武汉大学遗传学专业硕士
1978-03--1982-01武汉大学细胞生物学专业学士

学历博士

学位博士研究生

工作经历
工作简历2015-10~现在,发展中国家科学院,发展中国家科学院院士
2013-11~现在,中国科学院,中国科学院院士
2007-08~现在,中国科学院水生生物研究所,二级研究员
2001-11~2011-11,淡水生态与生物技术国家重点实验室,主任
1999-09~2007-11,中国科学院水生生物研究所,常务副所长、所长
1996-08~2001-11,淡水生态与生物技术国家重点实验室,副主任
1996-08~1996-08,中国科学院水生生物研究所鱼类遗传育种研究室,主任
1995-08~现在,中国科学院水生生物研究所鱼类遗传育种研究室、渔业生物技术研究中心,研究员、博导
1989-03~1995-08,中国科学院水生生物研究所鱼类遗传育种研究室,副研究员
1984-12~1989-03,中国科学院水生生物研究所鱼类遗传育种研究室,研究实习员、助理研究员、学术秘书

社会兼职2013-04-08-今,gene, 编委会成员
2007-10-01-2012-12-31,中国海洋湖沼学会, 副理事长
2007-07-20-2012-12-31,地（市、州、盟）科协副主席,
2005-07-01-今,中国水产学会, 副理事长
2003-07-01-今,中国遗传学会, 理事
1999-07-01-今,湖北省遗传学会, 理事
1995-06-01-今,中国鱼类学会, 理事


教授课程发育生物学
鱼类遗传育种学
高级遗传学
高级细胞生物学


专利与奖励
奖励信息（1） 湖北省科技突出贡献奖, 特等奖, 省级, 2015
（2） 全国先进工作者, 特等奖, 国家级, 2015
（3） 何梁何利基金科学与技术进步奖, 特等奖, 其他, 2015
（4） 中国科学院科技促进发展奖科技贡献奖, 一等奖, 部委级, 2014
（5） 黄颡鱼“全雄1号”的培育、工厂化育苗与推广应用, 二等奖, 省级, 2013
（6） 异育银鲫“中科3号”规模化繁育及产业化, 一等奖, 国家级, 2012
（7） 全雄黄颡鱼的研究, 一等奖, 院级, 2011
（8） 异育银鲫"中科3号"的培育和推广应用, 一等奖, 省级, 2011
（9） 多倍体银鲫独特的单性和有性双重生殖方式的遗传基础研究, 二等奖, 国家级, 2011
（10） 名特优淡水鱼养殖技术丛书, 二等奖, 省级, 2005
（11） 重要水产动物病毒病原的鉴定及致, 二等奖, 省级, 2004
（12） 银鲫两种生殖方式的遗传基础及其, 一等奖, 省级, 2003
（13） 复合四倍体异育银鲫的发现及其育, , 部委级, 1996
（14） 人工三倍体水晶彩鲫及其细胞遗传, 三等奖, 部委级, 1995

专利成果（ 1 ） Reproduction regulator enriched in the pituitary of E. coioides and use thereof, 发明, 2006, 第 2 作者, 专利号: U.S. Patent No. US7,098,314 B2
（ 2 ） Protein serine kinase SRPK1, 发明, 1996, 第 1 作者, 专利号: U.S. Patent No. 5,559,019
（ 3 ） 蛙病毒疫苗, 发明, 2001, 第 3 作者, 专利号: ZL**.9
（ 4 ） 银鲫品种培育和苗种生产的方法, 发明, 2004, 第 1 作者, 专利号: ZL 03 1 28109.5
（ 5 ） 大菱鲆弹状病毒毒株及其制备方法和应用, 发明, 2006, 第 3 作者, 专利号: ZL0.3
（ 6 ） 石斑鱼下丘脑富含的一个生殖调控因子的基因序列及其用途, 发明, 2004, 第 2 作者, 专利号: ZL 02 1 38831.8
（ 7 ） 石斑鱼垂体富含的一个生殖调控因子的基因序列及其用途, 发明, 2005, 第 2 作者, 专利号: ZL**.X
（ 8 ） 牙鲆淋巴囊肿病毒毒株及其制备方法和应用, 发明, 2006, 第 4 作者, 专利号: ZL2003 1 **.0
（ 9 ） 鳜鱼弹状病毒毒株及制备方法和应用, 发明, 2006, 第 4 作者, 专利号: ZL1.4
（ 10 ） 黄颡鱼性染色体特异分子标记及遗传性别鉴定方法, 发明, 2011, 第 1 作者, 专利号: ZL 2008 1 **.0


出版信息
发表论文（1）Zebrafish Lbh-like Is Required for Otx2-mediated Photoreceptor Differentiation,Int J Biol Sci,2015,通讯作者
（2）Characterization and sexual dimorphic expression of Cytochrome P450 genes in the hypothalamic-pituitary-gonad axis of yellow catfish,Gen Comp Endocr,2015,通讯作者
（3）Meiosis completion and various sperm responses lead to unisexual and sexual reproduction modes in one clone of polyploid Carassius gibelio,Sci Rep,2015,通讯作者
（4）Expression characterization, genomic structure and function analysis of fish ubiquitin-specific protease 18 (USP18) genes.,Dev comp Immunol,2015,通讯作者
（5）Identification of sex-specific markers reveals male heterogametic sex determination in Pseudobagrus ussuriensis,Mar Biotechnol (NY),2015,通讯作者
（6）omparative transcriptome analysis of differentially expressed genes and signaling pathways between XY and YY testis in yellow catfish,PLoS ONE,2015,通讯作者
（7）Molecular characterization and expression of an oocyte-specific histone stem-loop binding protein in Carassius gibelio,Comp Biochem Physiol B Biochem Mol Biol,2015,通讯作者
（8）A feedback regulatory loop involving p53/miR-200 and growth hormone endocrine axis controls embryo size of zebrafish,Sci Rep,2015,通讯作者
（9）Complete depletion of primordial germ cells in an all-female fish leads to sex-biased gene expression alteration and sterile all-male occurrence,BMC Genomics,2015,通讯作者
（10）Evolutionary history of two divergent Dmrt1 genes reveals two rounds of polyploidy origins in gibel carp,Mol Phylogenet Evol,2014,通讯作者
（11）C1q-like factor, a target of miR-430, regulates primordial germ cell development in early embryos of Carassius auratus,Int J Biol Sci,2014,通讯作者
（12） Proliferation and resistance difference of a liver-parasitized myxosporean in two different gynogenetic clones of gibel carp,Parasitol Res,2014,通讯作者
（13）Zebrafish Noxa promotes mitosis in early embryonic development and regulates apoptosis in subsequent embryogenesis,Cell Death and Differentiation,2014,通讯作者
（14）Sequence analysis and subcellular localization of crucian carp Carassius auratus viperin,Fish Shellfish Immunol,2014,通讯作者
（15）Grouper tshβ promoter-driven transgenic zebrafish marks proximal kidney tubule development,PLoS One,2014,通讯作者
（16）Type-IV antifreeze proteins are essential for epiboly and convergence in gastrulation of zebrafish embryos,Int J Biol Sci,2014,通讯作者
（17）Expression characterization of testicular DMRT1 in both Sertoli cells and spermatogenic cells of polyploid gibel carp,GENE,2014,通讯作者
（18）Fish viperin exerts a conserved antiviral function through RLR-triggered IFN signaling pathway,Dev Comp Immunol,2014,通讯作者
（19）Sex-biased miRNAs in gonad and their potential roles for testis development in yellow catfish,PLoS one ,2014,通讯作者
（20）Fish MAVS is involved in RLR pathway-mediated IFN response,Fish Shellfish Immunol,2014,通讯作者
（21）BMP and RA signaling cooperate to regulate Apolipoprotein C1 expression during embryonic development,GENE,2014,通讯作者
（22）Zebrafish IRF1 Regulates IFN Antiviral Response through Binding to IFN？1 and IFN？3 Promoters Downstream of MyD88 Signaling,J Immunol,2014,通讯作者
（23）A Comprehensive Transcriptome Provides Candidate Genes for Sex Determination/Differentiation and SSR/SNP Markers in Yellow Catfish,Mar Biotechnol (NY),2014,通讯作者
（24）Characterization and development of est-ssr markers derived from transcriptome of yellow catfish,Molecules,2014,通讯作者
（25）鱼类性别异形和性别决定的遗传基础及其生物技术操控,Genetic basis and biotechnological manipulation of sexual dimorphism and sex determination in fish,Sci China Life Sci,2014,通讯作者
（26）水产动物的病毒基因组及其病毒与宿主的相互作用,Virus genomes and virus-host interactions in aquaculture animals,Sci China Life Sci,2014,通讯作者
（27）黄颡鱼性别连锁标记Pf62-Y的染色体定位,水生生物学报,2014,通讯作者
（28）斑马鱼HO1基因的表达特征及功能研究,水生生物学报,2014,通讯作者
（29）Evidence for Paralichthys olivaceus IFITM1 antiviral effect by impeding viral entry into target cells,Fish Shellfish Immun,2013,第4作者
（30）Genome architecture changes and major gene variations of Andrias davidianus ranavirus (ADRV),Vet Res,2013,第2作者
（31）Microsatellite and mitochondrial DNA analysis of the genetic structure of Chinese horseshoe crab (Tachypleus tridentatus) in southeast China coast,African Journal of Biotechnology,2013,通讯作者
（32）cDNA cloning and expression of Acyl-CoA binding protein (ACBP) from orange-spotted grouper, Epinephelus coioides,Arch. Biol. Sci.,2013,第4作者
（33） Extensive diversification of MHC in Chinese giant salamanders Andrias davidianus (Anda-MHC) reveals novel splice variants,Dev Comp Immunol,2013,通讯作者
（34）一种雷氏放射孢子虫的鉴定及其特征描述,水生生物学报,2013,通讯作者
（35）动物眼睛的起源与进化研究进展,生物学杂志,2013,通讯作者
（36）线粒体COⅠ和16S rRNA片段确定近江蛏和缢蛏属的分类地位,水生生物学报,2013,通讯作者
（37）乌鳢一个养殖群体中性别连锁AFLP标记的筛选,水生生物学报,2013,通讯作者
（38）Identification of a novel Gig2 gene family specific to non-amniote vertebrates,PLoS ONE,2013,通讯作者
（39）Lineage-specific expansion of IFIT gene family: an insight into coevolution with IFN gene family, PLoS ONE ,2013,通讯作者
（40）Expression regulation of zebrafish interferon regulatory factor 9 by promoter analysis,Dev Comp Immunol,2013,通讯作者
（41）Introgression evidence and phylogenetic relationships among three (Para) Misgurnus species as revealed by mitochondrial and nuclear DNA markers,Arch. Biol. Sci.,2013,通讯作者
（42）Oocyte-specific H2A variant H2af1o is required for cell synchrony before mid-blastula transition in early zebrafish embryos,Biol Reprod,2013,通讯作者
（43）Apolipoprotein C1 regulates epiboly during gastrulation in zebrafish (cover article),Sci China Life Sci,2013,通讯作者
（44）Genetic differentiation and efficient sex-specific marker development of a pair of Y- and X-linked markers in yellow catfish,Int J Biol Sci,2013,通讯作者
（45）Gig1, a novel antiviral effector involved in fish interferon response,Virology,2013,通讯作者
（46） Transcription of Il17 and Il17f is controlled by conserved noncoding sequence 2,Immunity,2012,通讯作者
（47）Identification of DreI as an Antiviral Factor Regulated by RLR Signaling Pathway,PLoS ONE,2012,通讯作者
（48）Zebrafish dmrta2 regulates the expression of cdkn2c in spermatogenesis in the adult testis,Biology of Reproduction,2012,通讯作者
（49）High male incidence and evolutionary implications of triploid form in northeast Asia Carassius auratus complex,Mol Phylogenet Evol,2012,通讯作者
（50）Molecular regulation of interferon antiviral response in fish (review),Developmental and Comparative Immunology,2012,通讯作者
（51）Medaka piwi is essential for primordial germ cell migration,Curr Mol Med,2012,通讯作者
（52）Molecular basis and genetic improvement of economically important traits in aquaculture animals (review),Chin Sci Bull,2012,通讯作者
（53）Identification and characterization of one novel type of Triactinospomyxon with short spore axis,Parasitol Res,2012,通讯作者
（54）Subcellular localization and functional characterization of a fish IRF9 from crucian carp Carassius auratus,Fish Shellfish Immun,2012,通讯作者
（55）Genetic difference of Chinese horseshoe crab (Tachypleus tridentatus) in southeast coast of China based on mitochondrial COI gene analysis,Acta Oceanologica Sinica,2012,通讯作者
（56）Recent invasion and low level of divergence between diploid and triploid forms of Carassius auratus complex in Croatia,Genetica,2011,通讯作者
（57）An Apo-14 promoter-driven transgenic zebrafish that marks liver organogenesis,PLoS ONE,2011,通讯作者
（58）Fish MITA activation serves as a mediator for distinct fish IFN gene activation dependent on IRF3 or IRF7,Journal of Immunology,2011,通讯作者
（59）Cooperative roles of fish PKZ and PKR in IFN-mediated antiviral response,Journal of Virology,2011,通讯作者
（60）A novel cyanophage with cyanobacterial non-bleaching protein A gene in the genome,Journal of Virology,2011,第2作者
（61）A novel nucleo-cytoplasmic hybrid clone formed via androgenesis in polyploid gibel carp,BMC Res Notes,2011,通讯作者
（62）Characterization of fish IRF3 as an IFN-inducible protein reveals evolving regulation of IFN response in vertebrates,Journal of Immunology,2010,通讯作者
（63）Mtmr8 is essential for vasculature development in zebrafish embryos,BMC Developmental Biology,2010,通讯作者
（64）Fish virus-induced interferon exerts antiviral function through Stat1 pathway,Molecular Immunology,2010,通讯作者
（65）Dynamic distribution of spindlin in nucleoli, nucleoplasm and spindle from primary oocytes to mature eggs and its critical function for oocyte-to-embryo transition in gibel carp,J. Exp. Zool. part A,2010,通讯作者
（66）多倍体银鲫克隆多样性和双重生殖方式的遗传基础和育种应用,Genetic basis and breeding application on clonal diversity and dual reproduction modes in polyploid Carassius auratus gibelio,Sci. China Life Sci.,2010,通讯作者
（67）Antibacterial and Antiviral Roles of a Fish β-Defensin Expressed Both in Pituitary and Testis,PLoS ONE,2010,通讯作者
（68）Fish-specific duplicated dmrt2b contributes to a divergent function through Hedgehog pathway and maintains left-right asymmetry establishment function,PLoS ONE,2009,通讯作者
（69）Isolation of Y- and X-linked SCAR markers in yellow catfish and application in the production of all-male populations,Animal Genetics,2009,通讯作者
（70）Expression regulation and functional characterization of a novel interferon-inducible gene Gig2 and its promoter,Molecular Immunology,2009,通讯作者
（71）Evolutionary conservation of Dazl genomic organization and its continuous and dynamic distribution throughout germline development in gynogenetic gibel carp,J. Exp. Zool. Part B,2009,通讯作者
（72）Expression pattern, cellular localization and promoter activity analysis of ovarian aromatase (Cyp19a1a) in protogynous hermaphrodite red-spotted grouper,Molecular and Cellular Endocrinology,2009,通讯作者
（73）Histone H2A has a novel variant in fish oocytes,Biology of Reproduction,2009,通讯作者
（74）Cooperation of Mtmr8 with PI3K regulates actin filament modeling and muscle development in zebrafish,PLoS ONE,2009,通讯作者
（75）Molecular characterization of Chinese sturgeon gonadotropins and cellular distribution in pituitaries of mature and immature individuals,Molecular and Cellular Endocrinology,2009,通讯作者
（76）Functional domains and the antiviral effect of the dsRNA-dependent protein kinase PKR from Paralichthys olivaceu,Journal of Virology,2008,通讯作者
（77）C1q-like inhibits p53-mediated apoptosis and controls normal hematopoiesis during zebrafish embryogenesis,Developmental Biology,2008,通讯作者
（78）Clonal diversity and genealogical relationships of gibel carp in four hatcheries,Animal Genetics,2008,通讯作者

发表著作（ 1 ） RNA加工与细胞周期调控,RNA processing and Cell cycle Control,科学出版社,1998-07,第1作者
（ 2 ） 鱼类遗传育种工程,Genetic Breeding Engineering in Fish,上海科学技术出版社,1999-07,第2作者
（ 3 ） 发育生物学,Developmental Biology,科学出版社,2002-07,第1作者
（ 4 ） 异育银鲫实用养殖技术,practical breeding techniques in gibel carp,金盾出版社,2003-03,第1作者
（ 5 ） 鱼类性别和生殖的遗传基础及其人工控制,Genetic Basis and Artificial Control of Sexuality and Reproduction in Fish,科学出版社,2007-07,第1作者
（ 6 ） 水生病毒学,Aquatic Virology,高等教育出版社,2008-07,第2作者
（ 7 ） 水生病毒及病毒病图鉴,Atlas of Aquatic Viruses and Viral Diseases,科学出版社,2012-10,第2作者


科研活动
科研项目（ 1 ） 大宗淡水鱼类产业技术体系岗位科学家, 主持,国家级,2016-01--2020-12
（ 2 ） 长江江湖复合生态系统中的主要生物学问题研究, 主持,国家级,2012-01--2015-12
（ 3 ） 高产鲫新品种设计与培育, 主持,部委级,2013-08--2017-12

参与会议

合作情况
项目协作单位

指导学生已指导学生
汲广东 **
朱华平**
张义兵**
谢京**
徐红艳**
石耀华**
董彩华**
刘静霞**
夏建红**
杨林**
王忠卫**
李创举**
宁德刚**
姚波**
王锐**
陈玉栋**
胡成钰**
陈波**
周莉**
洪一江**
贾海波**
金珊**
毕永红**
尹隽**
史燕**
董彩文**
刘军**
朱蓉**
余祥勇**
李名友**
夏伟**
朱新平**
李风波**
马冬梅**
王红莹 **
汪洋**
夏军红**
王小磊**
耿凡锁**
翁朝红**
郭葳**
赵久刚**
吴南**
徐珊**
曹宏**
李洋洋**
王丹**
李琼**
孙敏**
黄伟**
梅洁**
彭金霞**
蒋珺**
李辰昱**
于非非**
刘庭凯**
刘沙**
金俊琰**
王达**
谢建丽**
蒋芳芳**
翟艳花**
肖青**
丹成**
岳华梅**
石军**
姜龙**
李熙银**
钟健翔**
孙钒**
毛剑锋**
李文华**
潘正军**
张君**
刘威**
王兵**
王伟**
刘珍**
洪玮**
丹成**
现指导学生
李石竹**
刘晓莉**
江诗雨**
何文霞**
邵光明**
朱要军**
丁苗**
皇培培**
陈帆**
王明涛**
甘瑞海**
鲁蒙**