基本信息
崔宗强 男 博导 武汉病毒研究所
电子邮件：czq@wh.iov.cn
通信地址：湖北武汉小洪山中区44号
邮政编码：430071

研究领域 研究方向：1）以艾滋病毒、流感病毒及新发烈性病毒为对象，研究病毒与宿主相互作用（活细胞、活体水平）的分子动态过程和机制，揭示病毒致病机理及宿主的应对机制；2）研究功能性病毒纳米组件和系统，发展病毒纳米疫苗与检测等新技术。
研究内容：1）单个病毒入侵细胞动态示踪；2）病毒-宿主相互作用机制；3）新型纳米疫苗。

招生信息招生病毒生物技术方向的博士研究生1名，硕士1-2名
招生专业071010-生物化学与分子生物学
071005-微生物学

招生方向 病毒学
微生物学
纳米生物学

教育背景 2002-09--2005-06 中国科学院武汉病毒研究所 博士
1999-09--2002-06 华中农业大学 硕士
1995-09--1999-06 华中农业大学 学士

学历2002.9-2005.7 博士 中科院武汉病毒所 微生物学专业
1999.9-2002.7 硕士 华中农业大学 微生物学专业
1995.9-1999.7 本科 华中农业大学 植保专业

学位2005年七月获得中国科学院武汉病毒研究所 博士学位

工作经历2011年7- 中科院武汉病毒所 病毒纳米生物学学科组长
2008.12-2011.6 中科院武汉病毒所 副研究员 病原分析与纳米生物学学科组
2005.7-2008.12 中科院武汉病毒所 助理研究员 病原分析与纳米生物学学科组
2009.12-2010.3 美国George Mason 大学，研究助理教授 艾滋病毒学科组

工作简历 2011-12--今 武汉病毒研究所 研究员
2011-07--今 中国科学院武汉病毒研究所 病毒纳米生物学 学科组长
2009-12--2010-03 美国George Mason 大学 研究助理教授
2008-12--2011-06 中国科学院武汉病毒研究所 病原分析与纳米生物学学科组 副研究员
2005-07--2008-12 中国科学院武汉病毒研究所 助理研究员

社会兼职

教授课程

专利与奖励2009年 中科院卢嘉锡青年人才奖
2006年 湖北省第十一届自然科学优秀论文一等奖
2006年 复旦大学谈家桢基金生命科学九源奖学金三等奖
2005年 中科院武汉病毒所所长奖学金特别奖
2009年 湖北省第十三届自然科学优秀论文二等奖
2010年 武汉市自然科学优秀学术论文二等奖

奖励信息 （1） 中科院卢嘉锡青年人才奖，部委级，2009
（2） 湖北省第十一届自然科学优秀论文，一等奖，省级，2006
（3） 复旦大学谈家桢基金生命科学九源奖学金，三等奖，研究所（学校）级，2006
（4） 中科院武汉病毒所所长奖学金，特等奖，研究所（学校）级，2005

专利成果 （1） 一种检测肿瘤纳米探针的制备方法，发明，2013，第2作者，专利号：ZL7.4
（2） 一种微RNA功能的双荧光报告系统的制备方法及应用，发明，2013，第1作者，专利号：ZL7.1


出版信息
1. Yingxin Ma^#, Mingxiu Wang^#, Wei Li, Zhiping Zhang, Xiaowei Zhang, Tianwei Tan, Xian-En Zhang^*, Zongqiang Cui^*. Live Cell Imaging of Single Genomic Loci with Quantum Dot-Labeled TALEs. Nat Commun, 2017, 8, 15318.
2. Qin Li^#, Wei Li^#, Wen Yin, Jia Guo, Zhiping Zhang, Dejun Zeng, Xiaowei Zhang, Yuntao Wu^*, Xian-En Zhang^*, and Zongqiang Cui^*. Single-Particle Tracking of Human Immunodeficiency Virus Type 1 Productive Entry into Human Primary Macrophages. ACS Nano, 2017, 11 (4), pp 3890–3903.
3. Xianxun Sun, Wei Li, Xiaowei Zhang, Mi Qi, Zhiping Zhang, Xian-En Zhang*, and Zongqiang Cui*. In Vivo Targeting and Imaging of Atherosclerosis Using Multifunctional Virus-Like Particles of Simian Virus 40. Nano Lett. 2016, 16, 6164?6171.
4. Minghai Chen#, Sanying, Liu#, Wei Li,Zhiping Zhang, Xiaowei Zhang, Xian-En, Zhang*, Zongqiang Cui*. Three-Fragment Fluorescence Complementation Coupled with Photoactivated Localization Microscopy for Nanoscale Imaging of Ternary Complexes. ACS Nano, 2016, 10 (9), 8482-8490.
5. Yingxin Ma, Zhike He, Tianwei Tan, Wei Li, Zhiping Zhang, Shuang Song, Xiaowei Zhang, Qinxue Hu, Peng Zhou, Yuntao Wu, Xian-En Zhang*, and Zongqiang Cui*. Real-Time Imaging of Single HIV-1 Disassembly with Multicolor Viral Particles. ACS Nano, 2016, 10 (6), 6273-6282.
6. Ding Gao, Xiuping　Lin, Zhiping Zhang, Wei Li,　Dong Men, Xian-En Zhang, Zongqiang Cui*. Intracellular cargo delivery by virus capsid protein-based vehicles: From nano to micro. Nanomedicine: Nanotechnology, Biology, and Medicine. 2016，12（2）：365-376.
7. Xiaowei Zhang, Fei Zhang, Xiaohe Ma, Xing Zhao, Wei Li, Zhiping Zhang, Jibin Zhang, Xian-En Zhang*, Zongqiang Cui*. Identification of interaction between HIV-1 glycoprotein 41 and integrase. Virologica Sinica, 2016, 31(5), 415-424.
8. Xiaowei Zhang, Zhenhua Zheng, Xijuan Liu, Bo Shu, Panyong Mao, Bingke Bai, Qinxue Hu, Minhua Luo, Xiaohe Ma, Zongqiang Cui* and Hanzhong Wang*. Tick-borne encephalitis virus induces chemokine RANTES expression via activation of IRF-3 pathway. Journal of Neuroinflammation, 2016, 13:209.
9. Siting Li, Minghai Chen, Qian Xiong, Jia Zhang, Zongqiang Cui*, and Feng Ge*. Characterization of the Translationally Controlled Tumor Protein (TCTP) Interactome Reveals Novel Binding Partners in Human Cancer Cells. J. Proteome Res., 2016, 15 (10), pp 3741–3751.
10. Yingxin Ma#, Zongqiang Cui#, Zhike He, Wei Li, Zhiping Zhang, Xiaowei Zhang, Xian-En Zhang*, Tianwei Tan*. Delaying Photobleaching of a Light-Switch Complex for Real-Time Imaging of Single Viral Particle Uncoating. Anal Chem. 2016, 88(21):10675-10679.
11. Zhaoyang Li, Zhiping Zhang, Lijun Bi, Zongqiang Cui, Jiaoyu Deng, Dian Bing Wang*, Xian-En Zhang*. Mutagenesis of mNeptune Red-Shifts Emission Spectrum to 681-685 nm. PLoS One, 2016, 11(4):e**.
12. Xiaowei Zhang, Zhenhua Zheng, Bo Shu, Panyong Mao, Bingke Bai, Qinxue Hu, Zongqiang Cui, Hanzhong Wang*. Isolation and characterization of a Far-Eastern strain of tick-borne　encephalitis virus in China. Virus Research, 2016，213: 6–
13. Xian-En Zhang*, Zongqiang Cui, Dianbing Wang. Sensing of biomolecular interactions using fluorescence complementing systems in living cells. Biosensors and Bioelectronics, 2016, 76, 243–250.
14. Ming-Hai Chen, Wei Li, Zhi-Ping Zhang, San-Ying Liu, Xiao-Wei Zhang, Xian-En Zhang*, Zong-Qiang Cui*. Novel near-infrared BiFC systems from a bacterial phytochrome for imaging protein interactions and drug evaluation under physiological conditions, Biomaterials, 2015, 48: 97-107
15. Dong Men#, Ting-ting Zhang#, Li-wei Hou, Juan Zhou, Zhi-Ping Zhang, Yuan-Yuan Shi, Jin-li Zhang, Zongqiang Cui, Jiao-Yu Deng, Dian-Bing Wang, and Xian-En Zhang, Self-Assembly of Ferritin Nanoparticles into an Enzyme Nano Composite with Tunable Size for Ultra-Sensitive Immunoassay, ACS Nano, 2015
16. Yu Han#, Shi-Feng Wang#, Zhi-Ping Zhang, Xiao-He Ma, Wei Li, Xiao-Wei Zhang, Jiao-Yu Deng, Hong-Ping Wei, Zhao-Yang Li, Xian-En Zhang*,Zong-Qiang Cui*. In vivo imaging of protein-protein and RNA-protein interactions using novel far-red fluorescence complementation systems, Nucleic Acids Res., 2014, 42: e103
17. Zongqiang Cui*. Interdisciplinary Research of Virology and Nanobiology, Austin Virol and Retrovirology. 1(1): 2. 2014
18. Zhao-Yang Li, Dian-Bing Wang, Zhi-Ping Zhang, Li-Jun Bi, Zong-Qiang Cui, Jiao-Yu Deng, Xian-En Zhang. The S28H mutation on mNeptune generates a brighter near-infrared monomeric, fluorescent protein with improved quantum yield and pH-stability, Acta Biochim Biophys Sin, 46: 802–809, 2014
19. Fei Zhao, Xu-De Wang, Luke N. Erber, Ming Luo, Ai-Zhen Guo, Shan-Shan Yang, Jing Gu, Breanna J. Turman, Yun-Rong Gao, Dong-Fang Li, Zong-Qiang Cui, Zhi-Ping Zhang, Li-Jun Bi, Anthony D. Baughn, Xian-En Zhang, Jiao-Yu Deng, Binding Pocket Alterations in Dihydrofolate Synthase Confer Resistance to para-Aminosalicylic Acid in Clinical Isolates of Mycobacterium tuberculosis, Antimicrobial Agents and Chemotherapy, 58(3): 1479–1487, 2014
20. Li Huang, Xiu-Mei Hu, Man Zhou, Yin-Mei Yang, Jin-Juan Qiao, Dian-Bing Wang, Jun-Ping Yu, Zong-Qiang Cui, Zhi-Ping Zhang, Xian-En Zhang, Hong-Ping Wei, Rapid Detection of New Delhi Metallo-β-Lactamase Gene and Variants codingCarbapenemase with Different Activity by a PCR-based in vitro protein expression method, J. Clin. Microbiol., doi:10.1128/JCM.03363-13, 2014
21. Juan Yin, Duan-Hao Zhu, Zhi-Ping Zhang, Wei Wang, Jin-Yu Fan, Dong Men, Jiao-Yu Deng, Hong-Ping Wei, Xian-En Zhang*, Zong-Qiang Cui*, Imaging of mRNA–Protein Interactions in Live Cells Using Novel mCherry Trimolecular Fluorescence Complementation Systems, PLOS ONE, 8(11): e80851, 2013
22. Ding Gao, Zhi-Ping Zhang, Feng Li, Dong Men, Jiao-Yu Deng, Hong-Ping Wei, Xian-En Zhang, Zong-Qiang Cui*, Quantum dot-induced viral capsid assembling in dissociation buffer, International Journal of Nanomedicine, 8: 2119–2128, 2013
23. Feng-Yun Li, Jun-PingYu, Zhi-Ping Zhang, Zong-Qiang Cui, Dian-Bing Wang, Hong-Ping Wei, Xian-En Zhang, Use of hGluc/tdTomato pair for sensitive BRET sensing of protease with high solution media tolerance, Talanta, 109: 141–146, 2013
24. Qun-Fang Zhang, Jing Gu, Peng Gong, Xu-De Wang, Shun Tu, Li-Jun Bi, Zi-Niu Yu, Zhi-Ping Zhang, Zong-Qiang Cui, Hong-Ping Wei, Sheng-Ce Tao, Xian-En Zhang, Reversibly acetylated lysine residues play important roles in the enzymatic activity of Escherichia coli N-hydroxyarylamine O-acetyltransferase, FEBS Journal, 280: 1966–1979, 2013
25. Dian-Bing Wang, Bo Tian, Zhi-Ping Zhang, Jiao-Yu Deng, Zong-Qiang Cui, Rui-Fu Yang, Xu-Ying Wang, Hong-Ping Wei, Xian-En Zhang, Rapid detection of Bacillus anthracis spores using a super- paramagnetic lateral-flow immunological detection system, Biosensors and Bioelectronics, 42: 661–667, 2013
26. Xiang-Yu You, Zhi-Ping Zhang, Jin-Yu Fan, Zong-Qiang Cui*, Xian-En Zhang, Functionally Orthologous Viral and Cellular MicroRNAs Studied by a Novel Dual-Fluorescent Reporter System, PLoS ONE, 7(4 ): e36157, 2012
27. Ya-Lan Liu, Zhi-Ping Zhang, Xing Zhao, Hong-Ping Wei, Jiao-Yu Deng, Zong-Qiang Cui*, Xian-En Zhang, Human cytomegalovirus UL94 is a nucleocytoplasmic shuttling protein containing two NLSs and one NES, Virus Research, 166 :31–42, 2012
28. Ke Li, Zhi-Ping Zhang, Ming Luo, Xiang Yu,Yu Han,Hong-Ping Wei, Zong-Qiang Cui*, Xian-En Zhang, Multifunctional ferritin cage nanostructures for fluorescence and MR imaging of tumor cells, Nanoscale, 4:188–193, 2012
29. Cui-Ling Zhang, Ding Gao, Guo-Hua Zhou, Lu Chen, Xian-En Zhang, Zong-Qiang Cui*, Zhi-Ke He, Label-Free Homogeneous Immunosensor Based on FRET for the Detection of Virus Antibody in Serum, Chem. Asian J., 7: 1764 – 1767,2012
30. Hang Yang, Dian-Bing Wang, Qiu-Hua Dong, Zhi-Ping Zhang, Zong-Qiang Cui, Jiao-Yu Deng, Jun-Ping Yu, Xian-En Zhang, Hong-Ping Wei, Existence of Separate Domains in Lysin PlyG for Recognizing Bacillus anthracis Spores and Vegetative Cells, Antimicrobial Agents and Chemotherapy, 56(10): 5031–5039, 2012
31. Feng-Yun Li, Jun-Ping Yu, Zhi-Ping Zhang, Zong-Qiang Cui, Dian-Bing Wang, Hong-Ping Weia, Xian-En Zhang, Buffer enhanced bioluminescence resonance energy transfer sensor based on Gaussia luciferase for in vitro detection of protease, Analytica Chimica Acta, 724: 104-110, 2012
32. Zong-Qiang Cui#, Qian Ren#, Hong-Ping Wei, Ze Chen, Jiao-Yu Deng, Zhi-Ping Zhang, Xian-En Zhang, Quantum dot–aptamer nanoprobes for recognizing and labeling influenza A virus particles, Nanoscale,3: 2454-2457, 2011
33. Ting-Juan Wang, Zhi-Ping Zhang, Ding Gao, Feng Li, Hong-Ping Wei, Xiao-Sheng Liang, Zong-Qiang Cui*, Xian-En Zhang, Encapsulation of gold nanoparticles by simian virus 40 capsids., Nanoscale. 3(10):4275-82, 2011
34. Yu Liang, Zhi-Ping Zhang, Hong-Ping Wei, Qin-Xue Hu, Jiao-Yu Deng, De-Yin Guo, Zong-Qiang Cui*, Xian-En Zhang. Aptamer beacons for visualization of endogenous protein HIV-1 reverse transcriptase in living cells., Biosens Bioelectron. 28(1):270-6, 2011
35. Wen-Wu Tian, Zong-Qiang Cui*, Zhi-Ping Zhang, Hong-PingWei, Xian-En Zhang*, Poliovirus 2Apro induces the nucleic translocation of poliovirus 3CD and 3C0 proteins, Acta Biochim Biophys Sin, 43: 38–44, 2011
36. Xu-De Wang, Jing Gu, Ting Wang, Li-Jun Bi, Zhi-Ping Zhang, Zong-Qiang Cui, Hong-Ping Wei, Jiao-Yu Deng, Xian-En Zhang, Comparative analysis of mycobacterial NADH pyrophosphatase isoforms reveals a novel mechanism for isoniazid and ethionamide inactivation., Mol Microbiol., doi: 10.1111/j.1365-2958, 2011
37. Wei Wang, Pan Zhang , Cui Hao, Xian-En Zhang, Zong-Qiang Cui, Hua-Shi Guan, In vitro inhibitory effect of carrageenan oligosaccharide on influenza A H1N1 virus, Antiviral Res. 92(2):237-46, 2011
38. Rong-Zhang Hao, Hong-Bin Song, Guo-Min Zuo, Rui-Fu Yang, Hong-Ping Wei, Dian-Bing Wanga, Zong-Qiang Cui, Zhi-Ping Zhang, Zhen-Xing Cheng, Xian-En Zhang, DNA probe functionalized QCM biosensor based on gold nanoparticle amplification for Bacillus anthracis detection., Biosens Bioelectron., 26(8):3398-404., 2011
39. Alyson Yoder, Jia Guo, Dong-Yang Yu, Zong-Qiang Cui, Xian-En Zhang, Yun-Tao Wu, Effects of Microtubule Modulators on HIV-1 Infection of Transformed and Resting CD4 T Cells, Journal of Virology, 85(6): 3020–3024, 2011
40. Xiao-Sheng Liang, Hong-Ping Wei, Zong-Qiang Cui, Jiao-Yu Deng, Zhi-Ping Zhang, Xiang-Yu You, Xian-En Zhang, Colorimetric detection of melamine in complex matrices based on cysteamine-modified gold nanoparticles, Analyst, 136: 179–183, 2011
41. Han Han#, Zong-Qiang Cui#, Wei Wang, Zhi- Ping Zhang, Hong-Ping Wei, Ya-Feng Zhou, Xian-En Zhang, New regulatory mechanisms for the intracellular localization and trafficking of influenza A virus NS1 protein revealed by comparative analysis of A/PR/8/34 and A/Sydney/5/97, J Gen Virol. 2010 Sep 8.
42. Yan Leng, Hong-Ping Wei, Zhi-Ping Zhang, Ya-Feng Zhou, Jiao-Yu Deng, Zong-Qiang Cui, Dong Men, Xiang-Yu You, Zi-Niu Yu, Ming Luo, Xian-En Zhang, Integration of a fluorescent molecular biosensor into self-assembled protein nanowires: a large sensitivity enhancement, Angew Chem Int Ed Engl., 49(40):7243-6, 2010
43. Dong Men, Zhi-Ping Zhang, Yong-Chao Guo, Duan-Hao Zhu, Li-Jun Bi, Jiao-Yu Deng, Zong-Qiang Cui, Hong-Ping Wei, Xian-En Zhang, An auto-biotinylated bifunctional protein nanowire for ultra-sensitive molecular biosensing, Biosens Bioelectron, 26: 1137–1141, 2010
44. Feng Li, Ke Li, Zong-Qiang Cui, Zhi-Ping Zhang, Hong-Ping Wei, Ding Gao, Jiao-Yu Deng, Xian-En Zhang, Viral Coat Proteins as Flexible Nano-Building-Blocks for Nanoparticle Encapsulation, Small, 2010, 6: 2301-2308.
45. Zong-Qiang Cui, Ke Zhang, Zhi-Ping Zhang, Ya-Lan Liu, Ya-Feng Zhou, Hong-Ping Wei, Xian-En Zhang, Visualization of the dynamic multimerization of human Cytomegalovirus pp65 in punctuate nuclear foci, Virology, 392: 169–177, 2009
46. Ya-Lan Liu#, Zong-Qiang Cui#, Zhi-Ping Zhang, Hong-Ping Wei, Ya-Feng Zhou, Ming-Li Wang, Xian-En Zhang, The tegument protein UL94 of human cytomegalovirus as a binding partner for tegument protein pp28 identified by intracellular imaging, Virology, 388: 68-77, 2009
47. Long-Yan Chen, Hong-Ping Wei, Yong-Chao Guo, Zong-Qiang Cui, Zhi-Ping Zhang, Xian-En Zhang, Gold nanoparticle enhanced immuno-PCR for ultrasensitive detection of Hantaan virus nucleocapsid protein, Journal of Immunological Methods, 346: 64-70, 2009
48. Dong Men, Yong-Chao Guo, Zhi-Ping Zhang, Hong-ping Wei, Ya-Feng Zhou, Zong-Qiang Cui, Xiao-Sheng Liang, Ke Li, Yan Leng, Xiang-Yu You, Xian-En Zhang, Seeding-Induced Self-assembling Protein Nanowires Dramatically Increase the Sensitivity of Immunoassays, Nano Letters, 9(6) : 2246-2250, 2009
49. Feng Li, Zhi-Ping Zhang, Jun Peng, Zong-Qiang Cui, Dai-Wen Pang, Ke Li, Hong-Ping Wei, Ya-Feng Zhou, Ji-Kai Wen, Xian-En Zhang, Imaging Viral Behavior in Mammalian Cellls with Self-Assembled Capsid-Quantum-Dot Hybrid Particles, Small, 5(6) : 718-726, 2009
50. Rong-Zhang Hao, Dian-Bing Wang, Xian-En Zhang, Guo-Min Zuo, Hong-Ping Wei, Rui-Fu Yang, Zhi-Ping Zhang, Zhen-Xing Cheng, Yong-Chao Guo, Zong-Qiang Cui, Ya-Feng Zhou, Rapid detection of Bacillus anthracis using monoclonal antibody functionalized QCM sensor, Biosensors and Bioelectronics, 24: 1330-1335, 2009
51. Wei Wang#, Zong-Qiang Cui#, Han Han, Zhi-Ping Zhang, Hong-Ping Wei, Ya-Feng Zhou, Ze Chen, Xian-En Zhang, Imaging and characterizing influenza A virus mRNA transport in living cells, Nucleic Acids Research, 36（15）: 4913-4928, 2008
52. Na Li#, Zong-Qiang Cui#, Zhi-Ping Zhang, Hong-Ping Wei, Ya-Feng Zhou, Xian-En Zhang, Live cell imaging of protein interactions in poliovirus RNA replication complex using fluorescence resonance energy transfer ( FRET ), Biochemical and Biophysical Research Communication, 368: 489-494, 2008
53. Hong-Ping Wei, Yan Kang, Zhi-Ping Zhang, Zong-Qiang Cui, Ya-Feng Zhou, Xian-En Zhang, Micellar electrokinetic chromatography and laser induced fluorescence detection of botulinum neurotoxin type A activity using a dual- labelled substrate, International Journal of Environmental Analytical Chemistry, 88(13) : 947-956, 2008
54. 樊晋宇, 崔宗强, 张先恩， 红色荧光蛋白的光谱多样性及体外分子进化, 生物化学与生物物理进展, 35( 10 ) : 1112-1120, 2008（Jin-Yu Fan, Zong-Qiang Cui, Xian-En Zhang, Optical Spectra Diversity and invitro Molecular Evolution of Red Fluorescent Proteins, Prog. Biochem. Biophys, 35( 10 ) : 1112-1120, 2008）
55. 樊晋宇，崔宗强，张先恩，双分子荧光互补技术，中国生物化学与分子生物学报，24 (8) : 767-774，2008 (Jin-Yu Fan, Zong-Qiang Cui, Xian-En Zhang, Bimolecular Fluorescence Complementation Technique, Chinese Journal of Biochemistry and Molecular Biology, 24 (8) : 767-774, 2008)
56. Chao Xu, Ya-Feng Zhou, Jiao-Yu Deng, Xiang Deng, Yong-Chao Guo, Zong-Qiang Cui, Zhi-Ping Zhang, Hong-Ping Wei, Li-Jun Bi, Xian-En Zhang, On-chip ligation of multiplexing probe-pairs for identifying point mutations out of dense SNP loci, Biosensors and Bioelectronics，24: 812-818, 2008
57. Hong-Ping Wei, Cen Qi, Xiao-Min Xu, Zhi-Ping Zhang, Ya-Feng Zhou, Zong-Qiang Cui, Xian-En Zhang, Cheng-Gang Zhang, Glycerol-salt Mediated Stacking of Nucleic Acids in CZE, Chromatographia, 67: 491-494, 2008
58. Jin-Yu Fan, Zong-Qiang Cui, Hong-Ping Wei, Zhi-Ping Zhang, Ya-Feng Zhou, Yun-Peng Wang, Xian-En Zhang, Split mCherry as a new red bimolecular fluorescence complementation sysrem for visualizing protein-protein interactions in living cells, Biochemical and Biophysical Research Communication, 367: 47-53, 2008
59. Zong-Qiang Cui, Zhi-Ping Zhang, Xian-En Zhang, Ji-Kai Wen, Ya-Feng Zhou, Wei-Hong Xie, Visualizing the dynamic behavior of poliovirus plus-strand RNA in living host cells, Nucleic Acids Research, 33(10) : 3245-3252, 2005






发表论文（1）1.Live cell imaging of single genomic loci with quantum dot-labeled TALEs,Nat Commun,2017,通讯作者
（2）Single-particle tracking of Human Immunodeficiency Virus Type 1 productive entry into human primary macrophages,ACS Nano,2017,通讯作者
（3）Three-fragment fluorescence complementation coupled with photoactivated localization microscopy for nanoscale imaging of ternary complexes,ACS Nano,2017,通讯作者
（4）Intracellular cargo delivery by virus capsid protein-based vehicles: From nano to micro,Nanomedicine: Nanotechnology, Biology, and Medicine,2016,通讯作者
（5）Real-Time Imaging of Single HIV?1 Disassembly with Multicolor Viral Particles,ACS NANO,2016,通讯作者
（6）In vivo targeting and imaging of atherosclerosis using multifunctional virus-like particles of Simian Virus 40,Nano Lett,2016,通讯作者
（7）Novel near-infrared BiFC systems from a bacterial phytochrome for imaging protein interactions and drug evaluation under conditions physiological,Biomaterials,2015,通讯作者
（8）In vivo imaging of protein–protein and RNA–protein interactions using novel far-red fluorescence complementation systems,Nucleic Acids Research,2014,通讯作者
（9）Imaging of mRNA-Protein interactions in live cells using novel mCherry trimolecular fluorescence complementation systems.,PLoS ONE,2013,通讯作者
（10）Quantum dot-induced viral capsid assembling in dissociation buffer,International Journal of Nanomedicine,2013,通讯作者
（11）Use of hGluc/tdTomato pair for sensitive BRET sensing of protease with high solution media tolerance,Talanta,2013,第4作者
（12）Rapid detection of Bacillus anthracis spores using a super- paramagnetic lateral-flow immunological detection system, Biosensors and Bioelectronics,2013,通讯作者
（13）Functionally orthologous viral and cellular microRNAs studied by a novel dual-fluorescent reporter system,PLoS ONE,2012,通讯作者
（14）Multifunctional ferritin cage nanostructures for fluorescence and MR imaging of tumor cells,Nanoscale,2012,通讯作者
（15）). Human cytomegalovirus UL94 is a nucleocytoplasmic shuttling protein containing two NLSs and one NES,Virus Research,2012,通讯作者
（16）Label-Free homogeneous immunosensor based on FRET for the detection of virus antibody in Serum,Chem Asian J,2012,通讯作者
（17）Aptamer beacons for visualization of endogenous protein HIV-1 reverse transcriptase in living cells,Biosens Bioelectron,2011,通讯作者
（18）Encapsulation of Gold Nanoparticles by Simian Virus 40 Capsids,Nanoscale,2011,通讯作者
（19）Quantum dot–aptamer nanoprobes for recognizing and labeling influenza A virus particles.,Nanoscale,2011,第1作者
（20）Poliovirus 2Apro induces the nucleic translocation of poliovirus 3CD and 3C’ Proteins.,Acta Biochim Sina,2011,通讯作者
（21）Visualization of the dynamic multimerization of human Cytomegalovirus pp65 in punctuate nuclear foci,Virology,2009,第1作者
（22）Visualizing the dynamic behavior of poliovirus plus-strand RNA in living host cells. ,Nucleic Acids Res,2005,第1作者

发表著作

科研活动承担项目/Grants
2015-2018国家自然科学基金面上项目一项 项目负责人
2015-2017国家自然科学基金重大项目一项 科研骨干
2011-2015中国科学院战略性先导科技专项子课题一项 项目负责人
2011-2013国家自然科学基金面上项目一项 项目负责人
2011-2013中国科学院“生命科学领域优秀青年科技专项”一项 项目负责人
2008-2010 国家自然科学基金青年科学基金项目一项 项目负责人
2007-2009 中国科学院知识创新工程青年人才领域前沿项目一项 项目负责人
2008-2010 武汉市“晨光计划”项目一项 项目负责人
2009-2013中国科学院知识创新工程重要方向项目一项 子课题负责人
2007-2010 国家重大科学研究计划项目一项 科研骨干
2010-2015 国家重大科学研究计划项目一项 科研骨干


近期重要国际会议报告
1.Cui,Zongqiang, “Imaging of viral RNAs using novel nano-fluorescent systems”, The Gordon Research Conference (RNA Nanotechnology), February 1-6, 2015. Ventura, CA, USA.
2.Cui,Zongqiang, “In vivo imaging of protein–protein and RNA–protein interactions using novel far-red fluorescence complementation systems” The 24th Anniversary World Congress on Biosensors, May 27-30, 2014. Melbourne, Australia.
3.Cui,Zongqiang, “Viral nanomaterials for biosensing”, The 22nd Anniversary World Congress on Biosensors, May 15-18, 2012. Cancun, Mexico.
4.Cui,Zongqiang, “Intracellular Cargo Delivery by Virus Protein-Based Vehicles”, International Conference on Nanomedicine and Nanobiotechnology, Apirl 6-9, 2015. Hangzhou, China.
其他国际国内会议：
IEEE-NANOMED（2007，澳门）
中国微米纳米技术学会纳米科学技术分会第二届年会暨2010’全国纳米生物与医学学术会议(2010，武汉)
Pacifichem 2010（2010，Hawaii）
香山会议（2011，北京）
“Imaging of pathogen-host interactions”（2008，Heidelberg）会议, 评为大会两位获奖报告之一
全国病毒学会议等
世界生物传感大会（2006，加拿大; 2008，上海)
等会议


合作情况2011-2015 国家重大科学研究计划项目
2011-2015 中国科学院战略性先导科技专项
2009-2013中国科学院知识创新工程重要方向项目
项目协作单位武汉大学
国家纳米中心
中国科学院广州生物医药与健康研究院
美国George Mason 大学

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