基本信息
刘祥军男硕导中国科学院化学研究所
电子邮件： xjliu@iccas.ac.cn
通信地址： 北京市海淀区中关村北一街2号
邮政编码： 100190

研究领域

招生信息
招生专业070302-分析化学

招生方向分子探针，分子识别材料
分离材料


教育背景2002-09--2007-06中国科学院化学研究所博士
1996-09--2000-07西安交通大学学士

学历
学位

工作经历
工作简历2009-12~现在,中国科学院化学研究所,副研究员
2007-07~2009-12,中国科学院化学研究所,助理研究员
2002-09~2007-06,中国科学院化学研究所,博士
1996-09~2000-07,西安交通大学,学士

社会兼职

教授课程分析化学实验-仪器分析
分析化学实验（基础化学实验II）
基础化学实验II（分析化学实验）


专利与奖励
奖励信息（1） 中国分析测试协会科学技术奖（CAIA奖）, 二等奖, 国家级, 2017

专利成果

出版信息
发表论文（1）Dual-Monitoring Glycosylation and Local pH in Live Cells by Metabolic Oligosaccharide Engineering with a Ratiometric Fluorescent Tag,Anal. Chem.,2019-10,第6作者
（2）A Nucleus-Targeting DNA Aptamer for Dead Cell Indication,ACS Sens.,2019-05,第6作者
（3）The Mechanism of the Selective Antiproliferation Effect of Guanine-Based Biomolecules and Its Compensation,ACS Chem. Biol.,2019-05,第6作者
（4）Comparative Study of the Chemical Constituents and Bioactivities of the Extracts from Fruits, Leaves and Root Barks of Lycium barbarum,Molecules,2019-04,第5作者
（5）Aptameric Probe Specifically Binding Protein Heterodimer Rather Than Monomers,Advanced Science,2019-04,第5作者
（6）In vitro selection of DNA aptamers recognizing drug-resistant ovarian cancer by cell-SELEX,Talanta,2019-03,第9作者
（7）Mitochondria-Targeted Ratiometric Fluorescent pH Probe,ACS Appl. Bio Mater.,2019-02,第1作者
（8）Thiazole orange modified carbon dots for ratiometric fluorescence detection of G-quadruplex and double-stranded DNA,ACS Appl. Mater. Interfaces,2018-07,第11作者
（9）Oxidative degradation of polyamines by serum supplement causes cytotoxicity on cultured cells,Scientific Reports,2018,第6作者
（10）Flow Cytometric Bead Sandwich Assay Based on a Split Aptamer,ACS Appl. Mater. Interfaces,2018,第3作者
（11）Microbead-Based Platform for Multiplex Detection of DNA and Protein,ACS Appl. Mater. Interfaces,2017,第1作者
（12）Quinacridone derivative as a new photosensitizer: photodynamic effects in cells and in vivo,Dyes and Pigments,2017,第4作者
（13）Development of squaraine based G-quadruplex ligands using click chemistry,Scientific Reports,2017,第4作者
（14）Dicyanomethylene Substituted Benzothiazole Squaraines: The Efficiency of Photodynamic Therapy In Vitro and In Vivo,EBioMedicine,2017,第5作者
（15）Detection of G-quadruplex structures formed by G-rich sequences from rice genome and transcriptome using combined probes,Anal. Chem.,2017,第6作者
（16）Triplex-quadruplex structural scaffold: a new binding structure of aptamer,Scientific Reports,2017,第5作者
（17）A Cyanine Dye to Probe Mitophagy: Simultaneous Detection of Mitochondria and Autolysosomes in Live Cells,J. Am. Chem. Soc.,2016,第5作者
（18）Intercellular Connections Related to Cell–Cell Crosstalk Specifically Recognized by an Aptamer,Angew. Chem., Int. Ed.,2016,第6作者
（19）Activity Enhancement of G-Quadruplex/Hemin DNAzyme by Flanking d(CCC),Chem. Eur. J.,2016,第4作者
（20）Interaction of hypericin with guanine-rich DNA: Preferential binding to parallel G-Quadruplexes,Dyes and Pigments,2016,第5作者
（21）Cytotoxicity of guanine-based degradation products contributes to the antiproliferative activity of guanine-rich oligonucleotides,Chem. Sci.,2015,第3作者
（22）Ratiometric fluorescent silver nanoclusters for the determination of mercury and copper ions,Anal. Methods,2015,第1作者
（23）Activity enhancement of G-quadruplex/hemin DNAzyme by spermine,RSC Adv.,2014,第4作者
（24）Fluorescence Light-Up Probe for Parallel G-Quadruplexes,Anal. Chem.,2014,第4作者
（25）Dicyanomethylene-Functionalized Squaraine as a Highly Selective Probe for Parallel G-Quadruplexes,Anal. Chem.,2014,第4作者
（26）Dual-Emission Silica Nanoparticles as a Ratiometric Nanosensor for Cu2+,Anal. Chem.,2014,第1作者
（27）A guanidine derivative of naphthalimide with excited-state deprotonation coupled intramolecular charge transfer properties and its application,J. Mater. Chem. C,2013,第4作者
（28）One-step real time RT-PCR for detection of microRNAs,Talanta,2013,第4作者
（29）A pH sensitive ratiometric fluorophore and its application for cellular pH measurement,J. Mater. Chem. B,2013,第4作者
（30）A turn-on fluorescent sensor for zinc and cadmium ion based on perylene tetracarboxylic diimide,Analyst,2013,第1作者
（31）Selective isolation of G-quadruplexes by affinity chromatography,J. Chromatogr. A,2012,第2作者
（32）Visual Detection of Hg2+ with High Selectivity Using Thymine Modified Gold Nanoparticles,Anal. Sci.,2010,第1作者
（33）Specific mercury(II) adsorption by thymine based sorbent,Talanta,2009,第1作者
（34）Highly Selective Phthalocyanine-Thymine Conjugate Sensor for Hg2+ Based on Target Induced Aggregation,Anal. Chem.,2009,第1作者
（35）Determination of methotrexate in human serum by high-performance liquid chromatography combined with pseudo template molecularly imprinted polymer,J. Chromatogr. A,2009,第1作者
（36）Molecularly Imprinted Polymer for Metsulfuron-Methyl by One-step Swelling and Polymerization Method,Talanta,2007,第1作者
（37）三甲氧苄啶分子印迹整体柱的制备及色谱性能,高等学校化学学报,2007,第1作者
（38）Molecularly Imprinted Polymer for Sulfamethoxazole and Molecular Recognition Properties in Aqueous Mobile Phase,Anal. Chim. Acta,2006,第1作者

发表著作

科研活动
科研项目（ 1 ） 核酸适配体功能化的磁性核壳纳米材料的制备及应用研究, 主持,国家级,2013-01--2016-12
（ 2 ） 重大疾病蛋白质标志物发现的新方法研究, 参与,国家级,2011-01--2015-12

参与会议

合作情况
项目协作单位

指导学生