基本信息
刘永宏男博导中国科学院南海海洋研究所
电子邮件: yonghongliu@scsio.ac.cn
通信地址: 广州市新港西路164号
邮政编码: 510301
研究领域主要研究领域为海洋生物活性物质的研究,以海洋天然产物化学研究为基础,以海洋生物中防治重要疾病创新药物先导结构的发现与优化为主要研究方向。主要研究内容包括:综合运用现代分离、分析技术与活性追踪相结合的方法,研究发现海洋生物中用于防治严重危害人类健康的重要疾病创新药物先导结构或目标分子;对发现的重要活性先导化合物进行系统的结构修饰或合成研究,探讨相关衍生物的结构与活性的关系,发现结构简单、活性强、毒性小的新药研究目标分子。
近年来,开展了一些海洋化学生态学研究,旨在通过海洋生物学,生态学和海洋天然产物化学等多学科的配合,从仿生学的观点,以抗污损生物附着活性筛选为导向,结合现代色谱学,现代波谱学,现代色谱-波谱联机技术,快速分离并结构确定海洋生物中的抗藤壶幼虫附着靶向化学防御物质,改构活性成分,发现生产新的抗附着先导结构,研究抗附着活性与结构关系,总结出显效基团,在此基础上进行抗其它污损生物附着活性的研究,探讨海洋生物抗附着化合物与环境竞争适应机制,揭示海洋生物的抗附着活性化合物的化学生态学作用,为研制海洋生物来源的新型无毒绿色防污剂奠定基础。
招生信息招收推免生硕士生,联合培养相关专业博士生,硕士生若干名 。
招生博士毕业工作人员及博士后人员
招生专业070703-海洋生物学100701-药物化学070321-化学生物学
招生方向海洋天然产物化学海洋化学生态学海洋药物学
教育背景1999-09--2002-08韩国釜山大学海洋天然药物化学专业博士1996-09--1999-08长春中医药大学天然药物化学专业硕士1992-09--1996-08长春中医药大学中药学学士
学历博士研究生
学位博士
出国学习工作2002年9月-2003年3月 韩国釜山大学 药学大学 博士后
2003年4月-2004年3月 日本大阪大学 药学大学 博士后
2004年4月-2005年12月 葡萄牙里斯本新大学 科技学院 化学系 博士后
工作经历2002年9月-2003年3月 韩国釜山大学 药学大学 博士后
2003年4月-2004年3月 日本大阪大学 药学大学 博士后
2004年4月-2005年12月 葡萄牙里斯本新大学 科技学院 化学系 博士后
2006年1月至今 中国科学院南海海洋研究所 研究员 博士生导师
工作简历2014-10~现在,中国科学院南海海洋研究所,海洋化学学科主任2010-10~现在,中国科学院南海海洋研究所,广东省海洋药物重点实验室副主任2006-01~2011-07,中国科学院南海海洋研究所,研究员2004-04~2006-01,葡萄牙里斯本新大学,博士后2003-04~2004-03,日本大阪大学,博士后2002-09~2003-03,韩国釜山大学,博士后
社会兼职2018-11-01-2023-10-31,中国药理学会海洋药物药理专业委员会, 常务委员
2018-01-01-今,药学学报, 编委
2017-01-01-今,Chem Biodivers, 编委
2016-01-01-今,Medicinal Chemistry (SCI 收录), 编委
2016-01-01-今,《天然产物研究与开发》, 编委
2013-01-01-今,中国药学会海洋药物专业委员会, 委员
2012-10-01-2014-12-31,natural product research, 编委
2012-01-01-今,中国生物化学与分子生物学学会 海洋生物化学与分子生物学分会, 理事
2011-01-01-2014-12-31,Journal of Arthritis编委, 编委
2011-01-01-2014-12-31,Journal of Medicinal Chemistry 编委,
教授课程生物有机化学海洋天然药物化学
科研活动
科研项目( 1 ) 海洋微生物次生代谢的生理与生态效应及其生物合成机制, 参与,国家级,2010-01--2014-12( 2 ) 重要生理功能和重大疾病相关蛋白质研究公共资源库建设, 参与,国家级,2011-01--2015-12( 3 ) 红树植物海芒果果实及其3株内生真菌抗海洋生物附着活性物质的发现, 主持,国家级,2013-01--2016-12( 4 ) 三种南海柳珊瑚中抗MRSA新八放烷二萜的发现,构效关系及作用机制研究, 主持,国家级,2012-01--2015-12( 5 ) 五株印度洋深海来源真菌中抗生物附着活性代谢产物的发现, 主持,国家级,2015-01--2018-12( 6 ) 三株南海深海真菌抗结核活性代谢产物的研究, 主持,国家级,2018-01--2021-12( 7 ) 广东省"特支计划"百千万工程领军人才项目, 主持,省级,2017-01--2019-12( 8 ) 海洋微生物中抗肾癌靶向药物先导化合物的 筛选和挖掘, 主持,省级,2018-01--2020-01( 9 ) 海洋来源船舶防污涂料关键技术研究及产业化, 参与,省级,2015-01--2017-01( 10 ) 深海微生物活性物质的化学生态效应与生物合成机制, 参与,部委级,2013-01--2017-12( 11 ) 海洋微生物中抗肾癌靶向药物先导化合物的筛选和挖掘, 主持,省级,2018-07--2022-06
参与会议(1)Marine Sponge-associated Microorganisms Metabolites and Their Bioactivities2018-09-25(2)海洋微生物活性物质研究第十届上海中医药与天然药物国际大会2017-10-29(3)海洋真菌毒素的研究第19届世界毒素大会2017-10-24(4)海洋微生物活性物质2015杨凌国际农业科技论坛2016-11-05(5)南海软珊瑚及其共生真菌活性物质的研究第十届海峡两岸细胞生物学术研讨会刘永宏2014-04-18(6)Bioactive Metabolites from the South China Sea Invertebrates第六届韩国海洋生物技术国际研讨会 yonghong liu2010-11-18
合作情况出站博士后:李云秋博士,柴兴云博士,林秀萍博士, 彭燕博士, M. Fredimoses博士(印度),Kuma博士(印度)
在站博士后:徐亮博士
项目协作单位
指导学生已指导学生
董光硕士研究生070703-海洋生物学
黄日明博士研究生070702-海洋化学
杨斌博士研究生070702-海洋化学
孙见凡博士研究生070702-海洋化学
胡静硕士研究生070702-海洋化学
连喜平博士研究生070703-海洋生物学
白志强硕士研究生070702-海洋化学
钟志龙硕士研究生070702-海洋化学
冼嘉韵硕士研究生070702-海洋化学
艾文博士研究生070702-海洋化学
李晋昇硕士研究生070702-海洋化学
汤勇硕士研究生070702-海洋化学
田永奇博士研究生070702-海洋化学
戴昱硕士研究生070702-海洋化学
庞小艳博士研究生070702-海洋化学
现指导学生
郭翠硕士研究生070703-海洋生物学
罗小卫博士研究生070703-海洋生物学
龙洁怡硕士研究生070703-海洋生物学
陈伟豪博士研究生070703-海洋生物学
陈春梅硕士研究生070703-海洋生物学
李坤龙博士研究生070703-海洋生物学
招聘中国科学院南海海洋研究所刘永宏研究员课题组2018年诚聘,微生物药物化学,药物化学,有机合成相关专业固定研究人员2名,药物化学/微生物学专业博士后2名,以及联合培养相关专业博士生,硕士生若干名。
本课题组隶属中国科学院南海海洋研究所,依托广东省海洋药物重点实验室和中国科学院热带海洋生物资源可持续利用重点实验室作为研究平台。主要开展海洋生物及其共附生微生物活性成分的天然产物化学和化学生态学研究。
固定人员及博士后应聘条件:
1. 拥有有机合成,天然产物化学或微生物学及其相关专业的博士学位;在所属学科领域发表过有影响的SCI论文。
2. 能够较独立地开展科研工作,中英文基础良好,能够撰写流畅的科研论文。
3. 工作勤奋,认真负责,有较强的团队协作精神。
应聘者请准备个人简历,直接与刘永宏研究员联系。
电话:(020) **
地址:广州市新港西路164号
欢迎通过E-mail:yonghongliu@scsio.ac.cn 咨询。
http://lmb.scsio.ac.cn/teamshow.asp?action=74
http://sourcedb.scsio.cas.cn/cn/rck/brjh/200907/t**_**.html
发表论文PangX,Lin X,Tian Y,Liang R,Wang J,Yang B,ZhouX,Kaliyaperumal K,Luo X,Tu Z, Liu Y*.Three new polyketides from the marine sponge-derived fungus Trichodermasp. SCSIO41004.Natural Product Research, 2018, 32(1), 105-111.
PangX,Lin X,Wang J, Liang R,Tian Y, SalendraL, Luo X,ZhouX,Yang B,Tu Z, Liu Y*.Three new highly oxygenated sterols and one new dihydroisocoumarin from the marine sponge-derived fungus Cladosporium sp . SCSIO41007. Steroids, 2017, doi.org/10.1016/j.steroids.2017.12.001.
Lei H, Lin X, Han L, Ma J, Dong K, Wang X, Zhong J, Mu Y, Liu Y, Huang X*. Polyketide derivatives from a marine-sponge-associated fungus Pestalotiopsis heterocornis. Phytochemistry, 2017, 142, 51-59.
Lin X,Li K, Yang L,Peng X, Fang W,Tian X,Liu Y,Zhou X.Dereplication and targeted isolation of bioactive sulphur compound from bacteria isolated from a hydrothermal field. Natural Product Research, 2017, DOI:10.1080/**.2017.**
JuZ, LinX,LiM,Wangy, TianY, WangJ, LiuJ, TuZ,XuS*,LiuY*. Chaetochromones A-C, Three New Polyketides from Mangrove Plant Derived Endophytic Fungus Phomopsissp. SCSIO 41006. Chemistry & Biodiversity, 2017,14(11), doi: 10.1002/cbdv..
Li P,Liu X,Zhu H,Tang X,Shi X,Liu Y*, Li G*. Unusual Inner-Salt Guaiazulene Alkaloids and bis-Sesquiterpene from the South China Sea Gorgonian Muriceides collaris. Scientific Reports, 2017, 7, 7697. DOI:10.1038/s41598-017-08100-z
Lin X, Wu Q, Yu Y, Liang Z, Liu Y, Zhou L*, Tang L*, Zhou X*. Penicilliumin B, a novel sesquiterpene methylcyclopentenedione from a deep sea-derived Penicillium strain with renoprotective activities.Scientific Reports, 2017, accept.
LiY,Wang J,He W,Lin X,Zhou X,Liu Y*.One Strain-Many Compounds Method for Production of Polyketide Metabolites Using the Sponge-Derived Fungus Arthrinium arundinisZSDS1-F3, Chemistry of Natural Compounds, 2017, 53(2), 373-374.
Lei H,Lin X,Han L,MaJ,Ma Q,Zhong J,Liu Y,Sun T,Wang J,Huang X.New Metabolites and Bioactive Chlorinated Benzophenone Derivatives Produced by a Marine-Derived Fungus Pestalotiopsis heterocornis. Marine Drugs,2017, 15(3), DOI:10.3390/md**
Luo X,Lin X,Salendra L,Pang X,Dai Yu,Yang Bin,LiuJuan,Wang J,Zhou X*,Liu Y*.Isobenzofuranones and Isochromenones from the Deep-Sea Derived Fungus Leptosphaeria sp. SCSIO 41005. Marine Drugs,2017, 15(7),DOI:10.3390/md**
Wang J,Liang R,Liao S,Yang B,Tu Z,LinX,Wang B,Liu Y*.Vaccinols J-S, ten new salicyloid derivatives from the marine mangrove-derived endophytic fungus Pestalotiopsis vaccinii.Fitoterapia, 2017, 120,164-170
Wang J,He W,Kong F,TianXP,Wang P, Zhou X,Liu Y*.Ochracenes A-I, Humulane-Derived Sesquiterpenoids from the Antarctic Fungus Aspergillus ochraceopetaliformis.Journal of Natural Products,2017, 6, 1725-1733.
Wang L, Wang J, Liu J, Liu Y*. Antitubercular Marine Natural Products. Current Medicinal Chemistry, 2017, 24, DOI:10.2174/6**1.
Luo X, Zhou X, Lin X, Qin X, Zhang T, Wang J, Tu Z, Yang B, Liao S, Tian Y, Pang X, Kaliyaperumal K, Li JL, Tao H, Liu Y*. Antituberculosis compounds from a deep-sea-derived fungus Aspergillus sp. SCSIO Ind09F01.Natural Product Research, 2017, 31(16), 1958-1962.
Liao SR,Tang Y,Xu L,Zhou XF,Wang JF, Yang B,Liu Y*. Ring-contraction from benzo[b][1,4]thiazines to benzo[d]thiazolines induced by oxygen. Tetrahedron2017, 73(1), 98-107.
Xian J, Lin X,Lu X, Wan J, Wang J, Zhou X, Ai W, Tu Z, LiuY*. Pestalachloride E, a new chlorinated benzophenone derivative from mangrove endophytic fungus Pestalotiopsis versicolor. Chinese Journal of Antibiotics2017,42, 8-13.
YangB,TaoH,QinX,WangZ,DongJ,LinX,ZhouX,LiJ,TuZ, LiuY*. Aspergone, a new chromanone derivative from fungus Aspergillussp. SCSIO41002 derived of mangrove soil sample. The Journal of Antibiotics2017, 6,788-790.
Chen S, Wang J, Wang Z, Lin X, Zhao B, Kaliaperumal K, Liao X, Tu Z, Li J, Xu S, Liu Y*.Structurally diverse secondary metabolites from a deep-sea-derived fungus Penicillium chrysogenum SCSIO 41001 and their biological evaluation. Fitoterapia, 2017, 17, 71–78.
He WJ, Zhou XJ, Qin XC, Mai YX, Lin X, Liao S, Yang B, Zhang T, Tu Z, Liu Y.* Quinone/hydroquinone meroterpenoids with antitubercular and cytotoxic activities produced by the sponge-derived fungus Gliomastix sp. ZSDS1-F7. Natural Product Research2017, 31(5), 604-609.
Wang JF, Qin XC, Chen Z, Ju Z, He W, Tan Y, Zhou XJ, Tu ZC,Lu F*,Liu Y*.Two new anthraquinones with antiviral activities from the barks of Morinda citrifolia(Noni).Phytochemistry Letters, 2016, 15, 13-15.
Zhao BQ,Peng S,He WJ,Liu YH,Wang JF, Zhou XJ. Antitubercular and cytotoxic tigliane-type diterpenoids from Croton tiglium. Bioorganic & Medicinal Chemistry Letters, 2016, 26(20), 4996–4999.
Kim A, Kim MJ, Noh TH, Hong J, Liu Y, Wei XY, Jung JH*.Synthesis and antibacterial evaluation of hamacanthin B analogues.Bioorganic & Medicinal Chemistry Letters, 2016, 26(20), 5013–5017.
Kim EL, Li J, Hong, J, Yoon WD, Kim HS, Liu Y, Wei X, Jung JH*.An unusual 1(10-19)abeosteroid from a jellyfish-derived fungus. Tetrahedron Letters,2016, 57(25), 2803-2806.
Wang H, Hong J, Yin J, Liu J, Liu Y, Choi JS, Jung, JH*.Paecilonic Acids A and B, Bicyclic Fatty Acids from the Jellyfish-Derived Fungus Paecilomyces variotii J08NF-1. Bioorganic & Medicinal Chemistry Letters, 2016, 26(9), 2220-2223.
XuG, Wang Z, Zhao B, Liu N, Yang S, Liu Y, Wang J*, Zhou X.*Saniculamins A and B, two new flavonoids from Sanicula lamelligera Hance inhibiting LPS-induced nitric oxide release.Phytochemistry Letters 2016, 18, 35-38.
LiuJ, JungJH, Liu Y.*Antimicrobial compounds from marine invertebrates-derived microorganisms.Current Medicinal Chemistry, 2016, 23(25): 2892-2905.
Chen S, Wang J, Lin X, Zhao B, Wei X, Li G, Kaliaperumal K, Liao S, Yang B, Zhou X, Liu J, Xu S, Liu Y*. Chrysamides A-C, three dimeric nitrophenyl trans-epoxyamides produced by the deep-sea-derived fungus Penicillium chrysogenum SCSIO41001. Organic Letters, 2016, 18, 3650-3653.
Liao S,Qin X,Wang Z, Li D,Xu L,Li J,Tu Z, Liu Y*Design, synthesis and cytotoxic activities of novel 2,5-diketopiperazine derivatives. European Journal of Medicinal Chemistry, 2016, 121, 500-509.
Wang J,Wei X,Qin X,TianX,Liao L,Zhou X,YangX, Wang F, Tu Z,Chen B,Liu Y.* Antiviral merosesquiterpenoids produced by an antarctic fungus Aspergillus ochraceopetaliformis SCSIO 05702. Journal of Natural Products, 2016, 79(1), 59-65.
WangJ,HeW, HuangX, TianX,LiaoS, YangB,WangF, ZhouX,LiuY*Antifungal new oxepine-containing alkaloids and xanthones fromthe deep-sea-derived fungus Aspergillus versicolorSCSIO 05879.JournalofAgriculture andFood Chemistry2016, 64, 2910-2916.
ZhouX,FangW, TanS, LinX, XunT,YangB,LiuS,LiuY.*Aspernigrins with anti-HIV-1 activities from the marine-derived fungus Aspergillus niger SCSIO Jcsw6F30. Bioorganic & Medicinal Chemistry Letters, 2016, 26, 361-365.
Tian Y,Lin X, Wang Z, Zhou X, Qin X, Kaliyaperumal K, Zhang T,Tu Z,Liu Y.*Asteltoxins with antiviral activities from themarine sponge-derived fungus Aspergillussp.SCSIO XWS02F40.Molecules,2016, 21(1), 34,doi:10.3390/molecules**
LiaoS ,Du L,QinX, XuL,WangJ,Zhou X, TuZ,LiJ*,LiuY*. Siteselective synthesis of cytotoxic 1,3,6-trisubstituted 3,6-diunsaturated (3Z,6Z)-2,5-diketopiperazines via a one-pot multicomponent method. Tetrahedron, 2016,72(8), 1051-1057.
Asperpyrone-Type Bis-Naphtho--Pyrones with COX-2-Inhibitory Activities from Marine-Derived Fungus Aspergillus niger. Fang W, Lin X, Wang J, LiuY, Tao H, Zhou X.MOLECULES, 2016, 21(7), DOI:10.3390/molecules**.
Ju ZR,Qin XC, Lin XP,Wang JF,Kaliyaperumal K,Tian YQ,Liu J,Liu F,Tu ZC,Xu SH,Liu Y*.New phenyl derivatives from endophytic fungus Botryosphaeria sp SCSIO KcF6 derived of mangrove plant Kandelia candel. Natural Product Research, 2016, 30(2), 192-198.
YangB, HuangJ, LinX, ZhangY, Tao H, Liu Y*. Anew diketopiperazine from the marine sponge Callyspongiaspecies. Records of Natural Products, 2016, 10 (1), 117-121.
Yang B, Huang J, Li X, Lin X, Zhou X, Tao H, Liu Y*. Isolation, Characterization, and Bioactivity Evaluation of Alkaloids from Soft Coral Sinularia kotanianensis. Chemistry of Natural Compounds, 2016,52(3),564-566.
Tao G, Liu J, Jung JH, Guo W, Wen XQ, LiuY*. Compounds from a jellyfish-derived fungus Aspergillus fumigates. Natural Product Sciences, 2016,22(2):82-86.
Wang H,Hong J,Yin J,Moon HR,Liu Y,Wei X,Oh DC,Jung JH*. Dimeric Octaketide Spiroketals from the Jellyfish-Derived Fungus Paecilomyces variotii J08NF-1.J Nat Prod.2015,78(11):2832-2836.
WangJ, WeiX, QinX, LinX, ZhouX, LiaoS,YangB,LiuJ, TuZ,LiuY*.Arthpyrones A–C, Pyridone alkaloids from a sponge-derived fungus Arthrinium arundinisZSDS1-F3. Organic Letters, 2015, 17,656?659.
LiaoS, XuY,TangY,WangJ, ZhouX,XuL,LiuY*. Design, synthesis and biological evaluation of soluble 2,5-diketopiperazines derivatives as potentialantifouling agents.RSC Advances2015, 5, 5, 51020–51026
Wang JF, He WJ, Qin XC, Wei XY, Tian XP,Liao L, Liao SR, Yang B, Tu ZC,Chen B,Wang FZ,Zhou XJ,Liu Y*.Three new indolyl diketopiperazine metabolites from the antarctic soil-derived fungus Penicillium sp SCSIO 05705. RSC Advances, 2015, 5(84), 68736-68742.
ZhangJ,LinX, LiL,ZhongB, LiaoX, LiuY*, XuS*Gliomasolides A–E, unusual macrolides from asponge-derived fungus Gliomastixsp. ZSDS1-F7-2? RSC Advances2015, 5, 54645–54648
BaiZ,LinX,WangJ, ZhouX,LiuJ, YangY, YangX, Liao S,Wang L, LiuY.*Newmeroterpenoidsfrom the endophytic fungus Aspergillus flavipes AIL8 derived fromthe mangrove plant Acanthus ilicifolius. Marine Drugs, 2015, 13, 237-248.
Liu J, Wei X, Kim E, Lin X, Yang X, Zhou X, Yang B, Jung J, Liu Y.*New glucosidated pyrazinoquinazoline indole alkaloids from fungus Aspergillus fumigatus derived of a jellyfish. Tetrahedron, 2015, 71, 271-275.
Wang J, Wang Z, Ju Z, Wan J, Liao S,Lin X, Zhang T, Zhou X,Chen H, Yang B, Tu Z,Liu Y.*Cytotoxic cytochalasins from marine-derived fungus Arthriniumarundinis ZSDS1-F3. PlantaMedica, 2015, 81, 160-166.
Li J, Huang L, Liu J, Song Y, Gao J, Jung J,Liu Y*, Chen G*. Acetylcholinesterase inhibitory dimeric indole derivatives from the marine actinomycetes Rubrobacter radiotolerans, Fitoterapia2015, 102, 203-207.
Wang JF, Yang SH, Liu YQ, Li DX,He WJ, Zhang XX,Liu Y*,Zhou XJ*.Five new phorbol esters with cytotoxic and selective anti-inflammatory activites from Croton tiglium. Bioorganic & Medicinal Chemistry Letters, 2015, 25(9), 1986-1989.
Wang L,Wang J,Wang L, Ma S, LiuY.*Anti-enterovirus 71 agents of natural products. Molecules2015, 20(9), 16320-16333.
Qin C, Lin X, Lu X, Wan J, Zhou X, Liao S, Tu Z, Xu S, Liu Y.*Sesquiterpenoids and xanthones derivatives produced by sponge-derived fungus Stachybotrysp. HH1 ZSDS1F1-2.The Journal of Antibiotics2015,68, 121-125
Ai W, Lin L, Wang Z, Lu X, Mangaladoss F, Yang X,Zhou X, TuZ, Liu Y.* Cladosporone A, a new dimeric tetralone from fungus Cladosporium sp. KcFL6’ derived of mangrove plant Kandelia candel.The Journal of Antibiotics2015, 68, 213-215.
Tian Y,Qin X,Lin X,KumaravelK,Zhou X,Liu J,Ju Z,Tu Z,Liu Y.*Sydoxanthone C and acremolin B produced by deep-sea-derived fungus Aspergillus sp. SCSIO Ind09F01. The Journal of Antibiotics2015, 68, 703-706.
Ju ZR,Lin XP,Lu X,Tu ZC,Wang JF,Kaliyaperumal K,Liu J, Tian YQ,Xu SHLiu Y.*Botryoisocoumarin A, a new COX-2 inhibitor from the mangrove Kandelia candel endophytic fungus Botryosphaeria sp KcF6.The Journal of Antibiotics2015, 68, 653-656.
Ai W, Lin X, Tu Z, Tian X, Lu X, Mangaladoss M, Zhong J, Liu Y.*Axinelline A, a new COX-2 inhibitor fromStreptomyces axinellaeSCSIO02208. Natural Product Research 2015, 68, 213-215.
Tian Y, LinX, Liu J, Kaliyaperumal K, Ai W, Ju J, Yang Y, Wang J, Yang X,LiuY.*Ascomycotin A, a new citromycetin analogue produced by Ascomycota sp. Ind19F07 isolated from deep sea sediment.Natural Product Research 2015,29(9), 820-826.
Sun J, Yang B, Zhou X, Yang X, Wang L, Liu Y.*A new briarane-type diterpenoid from the South China Sea Gorgonian Dichotella gemmacea. Natural Product Research 2015,29(9), 807-812.
Fredimoses M, Zhou X, Ai W, Tian X, Yang B, Lin X, Xian J, Liu Y.* Westerdijkin A, a new hydroxyphenylacetic acid derivative from deep sea fungus Aspergillus westerdijkiae SCSIO 05233.Natural Product Research 2015, 29(2), 158-162.
Wang J, Qin X, Xu F, Zhang T, Liao S, Lin X, Yang B, Liu J, Wang L, Tu Z, Liu Y*.Tetramic acid derivatives and polyphenols from sponge-derived fungus and their biological evaluation. Natural Product Research2015, 29(18), 1761-1765.
Yang B,Huang JX,Lin XP,Liao SR,Zhou XF, Liu J,Wang JF, Wang LS, Liu Y*. New casbane diterpenoids from the Hainan soft coral Sinulariaspecies. Helvetica Chimica Acta, 2015, 98(6), 834-841.
Wang, JF,Wei XY, Qin XC, Chen H,Lin XP,Zhang TY, Yang XW, Liao SR, Yang B,Liu J,Zhou XF,Tu ZC, Liu Y*.Two new prenylated phenols from endogenous fungus Pestalotiopsis vaccinii of mangrove plant Kandelia candel (L.) Druce. Phytochemistry Letters, 2015, 12, 59-62.
Huang, RM,Chen, YN,Zhou, XF, Yang, XW, Liu, Y*. A new N-Acyl taurine from the South China Sea marine sponge Callyspongia sp.Chemistry of Natural Compounds, 2015, 51(3), 540-541.
SunJ,WuY, YangB, LiuY.*Chemical constituents of marine sponge Halichondria sp.from South China Sea.Chemistry of Natural Compounds2015, 51(5), 975-977.
WangH, HongJ, YinJ, MoonH, LiuY, WeiX, OhD, JungJH. Dimeric Octaketide spiroketals from the jellyfish-derived fungus Paecilomyces variotii J08NF-1, Journal of Natural Products, 2015, 78(11), 2832-2836.
YangX,MiaoZ,MaX, ZhangG, Steinmetz A,Yang B,Wang J,Liu J, Liu Y, WangN. Asterolloside, a novel enolic saccharide from the sea star Asterias rollestoniBell. Tetrahedron Letters, 2015, 56,6174-6176.
Wang J, He W,Zhang X, Zhao B, Liu Y,Zhou X*. Dicarabrol, a new dimeric sesquiterpene from Carpesiumabrotanoides L. Bioorganic & Medicinal Chemistry Letters, 2015, 25, 4082-4084.
Wang B, Wang L, Li Y, Liu Y*. Heterocyclic terpenes: linear furano-and pyrroloterpenoids. RSC Advances2014,4, 12216-12234.
Lei H, Sun S, Han Z, Zhou X, Yang B, Liu Y*. Fragilisinins A-L, new briarane-type diterpenoids from gorgonianJunceella fragilis. RSC Advances 2014,4(10), 5261-5271.
Wang L, Zhou X, Fredimoses M, Liao S, Liu Y*. Naturally occurring organoiodines, RSC Advances2014, 4 (101), 57350- 57376.
Fredimoses M, Zhou X, Lin X, Tian X, Ai W, Wang W, Liao S, Liu J, Yang B, Yang X, Liu Y.*New prenylxanthones from the deep-sea derived fungus Emericellasp. SCSIO 05240.Marine Drugs2014, 12(6), 3190-3202.
Yang B,Wei X,Huang J,Lin X,Liu J,Liao S,Wang J,Zhou X,Wang L,Liu Y*. Sinulolides A-H, New Cyclopentenone and Butenolide Derivatives from Soft Coral Sinularia sp. Marine Drugs, 2014, 12(10), 5316-5327.
Liao S, Qin X, Li D, Tu Z, Li J, Zhou X, Wang J, Yang B, Lin X, Liu J, Yang X, Liu Y*. Design and synthesis of novel soluble 2,5-diketopiperazine derivatives as potential anticancer agents. European Journal of Medicinal Chemistry, 2014, 83, 236-244.
72.Yang B, Dong J, Lin X, Zhou X, Zhang Y, Liu Y*. New prenylated indole alkaloids from fungus Penicillium sp. derived of mangrove soil sample. Tetrahedron, 2014, 70(25), 3859–3863. Ai W, Wei X, Lin X,Sheng L, Wang Z, Tu Z, Yang X,Zhou X, Li J, Liu Y.*Guignardins A-F, spirodioxynaphthalenes from the endophytic fungus Guignardia sp KcF8 as a new class of PTP1B and SIRT1 inhibitors. Tetrahedron, 2014, 70(35), 5806-5814.
Wang J, Wei X, Lu X,Xu F, Wan J, Lin X, Zhou X,Liao S,Yang B, Tu Z, Liu Y.*Eight new polyketide metabolites fromthe fungus Pestalotiopsis vaccinii endogenous with the mangrove plant Kandelia candel (L.) Druce. Tetrahedron, 2014,70, 9695-9701.
Fang W, Lin X, Zhou X, Ai W, Lin J. Yang B, Tu C, Liu Y.*Cytotoxic and antiviral sesquiterpenoid nitrobenzoyl esters from the marine-derived fungus Aspergillus sp. Jcma1F17.MedChemComm 2014, 5, 701-705.
Bai Z, Lin X, Wang Y, Wang J, Zhou X, Yang B, Liu J, Yang X, Wang Y, Liu Y* New phenyl derivatives from endophytic fungus Aspergillus flavipes AIL8 derived of mangrove plant Acanthus ilicifolius. Fitoterapia, 2014, 95, 194-202.
Sun J, Lin X, Zhou X, Wan J, Zhang T, Yang B, Yang X, Tu Z, Liu Y*. Pestalols A-E, New AlkenylPhenoland Benzaldehyde Derivatives from Endophytic Fungus Pestalotiopsis sp. Acbc2 Isolated from the Chinese Mangrove Plant Aegiceras corniculatum. The Journal of Antibiotics 2014, 67(6), 451-457.
Wang J, Lin X, Qin Z, Liao S, Wan J, Zhang T, Liu J, Fredimoses M, Chen H, Yang Y, Zhou X, Yang X, Tu Z, Liu Y*. Antimicrobial and Antiviral Sesquiterpenoids from Sponge-Associated Fungus, Aspergillus sydowiiZSDS1-F6.The Journal of Antibiotics2014, 67(8), 581-583.
Liao S, Qin C,Yao P, Li J, Zhou X,Wang J, Huang Z, Liu Y.*A One-PotSynthesis of Unsaturated, Polysubstituted 3-Aminoazepan-2-ones. Synthesis 2014, 46(5), 621-628.
Yang X, Li S, Li Y, Feng L, Shen Y, Lin S, Tian J, Zeng H, Wang N, Steinmetz A, Liu Y, Zhang W. Chemical constituents of Abies delavayi.Phytochemistry, 2014, 105, 164-170.
Peng Y, Huang R, Hu J, Zhou X, Yang B, Liu L, Yang X, Liu Y*. Bioactive chemical constituents of the South China Sea starfish Stellaster equestris. Chemistry of Natural Compounds, 2014, 50(1), 184-185.
Huang R, Yan T, Peng Y, Zhou X, Yang X, Liu Y.Diketopiperazines from the marine spongeAxinellasp. Chemistry of Natural Compounds, 2014, 50(1), 191-193.
Wang J, Xu F, Wang Z, Lu X, Wan J, Yang B, Zhou X, Zhang T, Tu Z, Liu Y*A new naphthalene glycoside from the sponge-derived fungus Arthrinium arundinisZSDS1-F3. Natural Product Research2014, 28(14), 1070-1074.
Yang B, Dong J, Lin X, Tao H, Zhou ZLiu Y.Xylaolide A, a new lactonefrom the fungusXylariaceaesp. DPZ-SY43. Natural Product Research 2014,28(13), 967-970.
Zhou X, Sun J, Ma W, Fang W, Chen Z, Yang B, Liu Y*. A new aromatic amine from fungus Pestalotiopsis vaccinii. Phytochemistry Letters2014, 7, 35-37.
Zhou X, Sun J, Ma W, Fang W, Chen Z, Yang B, Liu Y*. Bioactivities of six sterols isolated from marine invertebrates. Pharmaceutical Biology2014, 52(2), 187-190.
Yang B,Tao H, Zhou X,Lin X, Liu Y*.Two new alkaloids from marine sponge Callyspongia sp.Natural ProductResearch2013, 27(4-5),433-437.
Wang L, Yang B, Lin X, Zhou X, Liu Y*. Sesterterpenoids, Natural Product Report2013, 30, 455-473.
Yang B, Liao S, Lin X, Wang J, Liu J, Zhou X, Yang X, Liu Y*. New Sinularianin Sesquiterpenes from Soft CoralSinulariasp.Marine Drugs, 2013, 11, 4747-4750.
Yang X, Peng K, Liu Z, Zhang G, Li J, Wang N,Steinmetz A, Liu Y. Strepsesquitriol, a Rearranged Zizaane-Type Sesquiterpenoid from the Deep-Sea-Derived Actinomycete Streptomycessp. SCSIO 10355.Journal of Natural Product 2013, 76, 2360-2363.
Sun J, Han Z, Zhou X, Yang Y, Lin X, Liu J, Peng Y, Yang X, Liu Y*. Antifouling briarane type diterpenoids from South China Sea gorgonians Dichotella gemmacea, Tetrahedron2013, 69, 971-880.
Zhou X, Liu J,Yang B, Lin X, Yang X, Liu Y*. Marine Natural Products with Anti-HIV Activities in the Last Decade, Current Medicinal Chemistry2013, 20(7), 953-973.
Yang X, Zhang G, Ying J, Yang B, Zhou X, Steinmetz A, Liu Y*. Wang N.Isolation, characterization, and bioactivity evaluation of 3-((6-methylpyrazin-2-yl) methyl)-1H-indole, a new alkaloid from a deep-sea-derivated actinomycete Serinicoccus profundi sp. nov. Marine Drugs 2013, 11, 33-39.
Huang RM, Peng Y, Zhou XF, Yang X, Liu Y*. A new taurine derivative from South China Sea marine sponge Axinellasp.Natural Product Research2013, 27(17),1537-1541.
Huang RM, Peng Y, Zhou XF, Fu MQ, Tian S, Liu Y*. A new pyrimidinedione derivative from the gorgonian coral Verrucellaumbraculum.Natural Product Research2013, 27(4-5),319-322.
Zhou X, Lin X, Guo X, Yang Y, Yang X, Liu Y*. Chemical Constituents of the Sponge Mycale Species from South China Sea, Records of Natural Products2013, 7, 119-123.
Yang B, Zhou X, Huang H, Yang X, Liu J, Lin X, Li X, Peng Y, Liu Y*.New cembrane diterpenoids from a Hainan soft coral Sinularia sp. Marine Drugs 2012, 10, 2023-2032.
Yang B, Zhou X, Lin X, Liu J, Peng Y, Yang X,Liu Y*. Cembrane diterpenes chemistry and biological properties. Current Organic Chemistry2012, 16(12), 1512-1539.
ChenJ, Lan X, LiuY*, Jia A.In vitroeffects of natural diketopiperazines on release of cytokines and chemokines in J774A.1 macrophages. Bioorganic Medicinal ChemistryLetter 2012, 16, 3177-3180.
Lin X, Zhou X, Wang F, Liu K, Yang B, Yang X, Peng P, Liu L, Ren Z,Liu Y*. A new cytotoxic sesquiterpene quinone produced by Penicilliumsp. F00120 isolated from a deep sea sediment sample. Marine Drugs 2012, 10, 106-115.
Kim E, Li J, Dang H, Hong J, Lee C, Kim D, Yoon W, Kim E, Liu Y, Jung J.Cytotoxic cytochalasins from the endozoic fungus Phoma sp. of the giant jellyfish Nemopilema nomurai. Bioorganic & Medicinal Chemistry Letters2012, 22, 3126–3129.
Li W, Wang L, Zhao D, Liu Y*. Steroidal alkaloids from Veratrum nigrumL.Chemistry of Natural Compounds2012, 48(5), 919-920.
He WH, Lin L, Xu T, Jung JH, Yin H, Yang B, Liu Y*. A new norsesterterpenoid from the sponge species Sarcotragus. Chemistry of Natural Compounds2012, 48(2), 208-210.
Peng Y, Xie E, Zheng K, Fredimoses M, Yang Y, Zhou X, Wang Y, Yang B, Lin X, Liu J, Liu Y*.Nutritional and Chemical Composition and Antiviral Activity of Cultivated Seaweed Sargassum naozhouenseTseng et Lu. Marine Drugs 2013, 11, 20-32.
Huang R, Wang B, Liu Y*. Briarane-type diterpenoids from the gorgonian coral Verrucella umbraculum. Chemistry of Natural Compounds 2012, 48(3), 516-517.
Yang B, Hu J, Lei H, Chen XC, Zhou XF, Liu Y*. Chemical constituents of marine sponge Callyspongia sp. from the South China Sea. Chemistry of Natural Compounds 2012, 48(2), 350-351.
Liao X, Tang L, Liang Y, Jian S, Xu S, Liu Y*. New pentahydroxylated steroids from the South China Sea gorgonian Subergorgia suberosaChemistry & Biodiversity2012, 9, 370-375.
Liu Y*. Renaissance of marine natural product drug discovery and development. Journal of Marine Science Research & Development2012,2, 1000e106.
Sun J, Huang H, Chai X, Yang X, Meng L, Huang C, Zhou X, Yang B, Hu J, Chen X, Lei H, Wang L, Liu Y*. Dichotellides A-E, five new iodine-containing briarane type diterpenoids from Dichotella gemmacea. Tetrahedron2011, 67, 1245-1250.
Wang L, Zhao D, Di L, Xu T, Lin X, Yang B, Zhou X, Yang X, Liu Y*. The analgesic and anti-rheumatic effects of Thladiantha dubiafruit crude polysaccharide fraction in mice and rats.Journal of Ethnopharmacology2011, 137, 1381-1387.
Zhou X, Lu Y, Lin X, Yang Y, Yang X, Liu Y.Brominated aliphatic hydrocarbons and sterols from the sponge Xestospongia testudinariawith their bioactivities Chemistry and Physics of lipids 2011,164, 703-706.
Yang X, Li Y, Li S, Shen Y, Tian J, Zhu Z, Feng L, Wu, L, Lin, S, Wang, N, Liu Y, Zhang W. Mono- and sesquiterpenoids, flavonoids, lignans, and other miscellaneous compounds of Abies georgei. Planta Medica2011, 77(7), 742-748.
WangL, ZhaoD, DiL,ChengD, ZhouX, YangX, LiuY*.The anti-hyperplasiaofmammaryglandeffectof Thladiantha dubiaroot ethanol extract inratsreducedbyestrogenandprogestogen. Journal of Ethnopharmacology2011, 134, 136-140.
Yang X, Dong G, Zhou X, Chai X, Li Y, Yang B, Zhang W, Liu Y*. Isolation and structural characterisation of five new and 14 known metabolites from the commercial starfish Archaster typicusFood Chemistry 2011, 124, 1634-1638.
Liu Y*, Yan H, Wen K, Zhang J, Xu T, Wang L, Zhou X, Yang X. Identification of epidioxysterol from South China Sea urchin Tripneustes gratillaLinnaeus and its cytotoxic activity. Journal of Food Biochemistry2011, 35, 932-938.
Hu J, Yang B, Lin X, Zhou X, Yang X, Long L, Liu Y*.Chemical and Biological Studies of Soft Corals Nephtheidae Family.Chemistry& Biodiversity2011, 8, 1011-1032.
Dong G, Yang X, Zhou X. Liu Y*.Chemical constituents and bioactivities of starfish. Chemistry & Biodiversity2011, 8(5), 740-791.
Huang R, Zhou X, Peng Y, Yang X, Xu T,Liu Y*. Nucleosides from the marine sponge Callyspongia sp. Chemistry of Natural Compounds2011, 46, 1010-1011.
Liu Y*, Jung J, Xu T, Long LJ, Lin XP, Yin H., Yang B, Zhou XF, Yang XW.New cyclitol derivative from a sponge Sarcotragus species. Natural Products Research2011, 25(6), 648-652.
Chai X, Sun J, Tang L, Yang X, Li Y, Huang H, Zhou X, Yang B, Liu Y*.A novel cyclopentene derivative and a polyhydroxylated steroid from a South China Sea gorgonian Menella sp.Cheimcal & Pharmaceutical Bulletin 2010, 58(10), 1391-1394.
Liu J, Wang L, Zhao D, Cheng D, Xu T, Zhou X, Yang X, Liu Y*. A new lignan from Saururus chinensis. Chemistry of Natural Compounds 2010, 46(4), 631-632.
Zhou X, Xu T, Yang X, Xu S, Liu Y*. Chemical and biological aspects of marine sponge of the genus Xestospongia. Chemistry & Biodiversity 2010, 7, 2201-2227.
Wang L, Zhou X, Xu T, Yang X, Liu Y*. Lignans from Saururus chinensis.Chemistry of Natural Compounds2010, 46(3), 451-452.
Peng Y, Zheng J, Huang R, Wang Y, Xu T, Zhou X, Liu Q, Zeng F, Ju H, Yang X, Liu Y*.Polyhydroxysteroids and saponins from the China Sea starfish Asterinasp. and their biological activities.Chemical & Pharmaceutical Bulletin2010, 58(6),856-858.
Zhou X,Liu Y, Tang L, Zhang P, Wu J. Chemical constituents from the roots of Actinidia chinensis.Chemistry of Natural Compounds 2010, 46(2), 308-309.
Huang L, Wen K, Gao X, Liu Y*. Hypolipidemic effect of fucoidan from Laminaria japonicain hyperlipidemic rats. Pharmaceutical Biology2010, 48(4), 422-426.
Huang R, Ma W, Dong J, Zhou X, Xu T, Lee K,Yang X, Xu S, Liu Y*. A new 1,4-diazepine from South China Sea marine sponge Callyspongia species. Molecules2010, 15, 871-877.
Yang X, Li S, Wu L, Li Y, Feng L, Shen Y, Tian J, Tang J, Wang N, Liu Y, Zhang W. Abiesatrines A-J: anti-inflammatory and anti-tumor triterpenoids from Abies georgeiOrr. Organic & Biomolecular Chemistry 2010, 8, 2609-2616.
Ren S, Ma W, Xu T, Lin X, Yin H, Yang B, Zhou X, Yang X, Long L, Lee K, Gao Q, Liu Y*. Two novel alkaloids from the South China Sea marine sponge Dysidea sp.Journal of Antibiotics 2010,63, 699-701.
Huang R, Zhou X, Xu T, Yang X, Liu Y*. Diketopiperazines from marine organisms. Chemistry & Biodiversity 2010, 7, 2809-2829.
Yang X, Li S, Li Y, Xia J, Wu L, Shen Y, Tian J, Wang N, Liu Y, Zhang W. Abiespiroside A, an Unprecedented Sesquiterpenoid Spirolactone with a 6/6/5 Ring System from Abies delavayi. European Journal of Organic Chemistry 2010, 34, 6531-6534.
Xu Y, Liu Y, Xu T, Xie S, Si Y, Liu Y, Zhou H, Liu T, Xu D. A new furostanol glycoside from Tribulus terrestris. Molecules2010,15,613-618.
Xu Y, Bai L, Liu Y, Xu T, Liu Y, Xie S, Si Y, Zhou H, Liu T, Xu D. A new triterpenoid saponin from Pulsatilla cernua.Molecules2010, 15, 1891-1897.
Lei H, Zhou X, Yang Y, Xu T, Yang X, Sun J, Yang Y, Hu J, Lin X, Long L, Liu Y*. Bryostatins from South China Sea bryozoan Bugula neritinaL. Biochemical Systematics and Ecology 2010, 38, 1231-1233.
Zhou X, Wen K, Yang X, Huang R, Dong G, Yang B, Sun J, Liu Y*. Chemical constituents from the sea urchin Glyptocidaris crenularis.Biochemical Systematics and Ecology 2010, 38, 103-105.
Yang X, Feng L, Li S, Liu X, Li Y, Wu L, Shen Y, Tian J, Zhang X, Liu X, Wang N, Liu Y, Zhang, W. Isolation, structure, and bioactivities of abiesadines A–Y, twenty-five new diterpenes from Abies georgei Orr.Bioorganic Medicinal Chemistry2010, 18, 744-754.
Wang L, Cheng D, Wang H, Di L, Zhou X, Xu T, Yang X, Liu Y*. The hepatoprotective and antifibrotic effects of Saururus chinensis against carbon tetrachloride induced hepatic fibrosis in rats. Journal of Ethnopharmacology2009, 126, 487-491.9
Wang L, Zhao D, Xu T, Zhou X, Yang X, Liu Y*. A new triterpene hexaglycoside from the bark of Kalopanax septemlobus (Thunb.) Koidz.Molecules2009, 14, 4497-4504.1
Zhou X, Tang L,Liu Y. An isomeric mixture of novel cerebrosides isolated from Impatiens pritzelliireduces lipopolysaccharide-induced release of IL-18 from human peripheral blood mononuclear cells. Lipids2009, 44(8), 759-763.2
Zhou X, Tang L, Zhang P, Zhao X, Pi H, Zhang Y, Ruan H, Liu Y, Wu J. The interleukin-18 inhibitory activities of echinocystic acid and its saponins from Impatiens pritzellii var. hupehensis. Zeitschrift Fur Naturforschung 2009, 64c, 369-372.3
Wang L, Zhao D, Liu Y*. GC-MS analysis of the supercritical CO2fluid extraction of Ephedrasinicaroots and its antisudorific activity. Chemistry of Natural Compounds 2009, 45(3), 434-436.2
Wang B, Dong J, Zhou X, Lee KJ, Huang R, Zhang S, Liu Y*. Nucleosides from marine sponges including known ones from Haliclonasp. Zeitschrift Fur Naturforschung 2009, 64c, 143-148.0
Wang B, Lee K, Zhang S, Jung J, Liu Y*. 2-Palmitamidoethanesulfonic acid, new aminoethylsulfonic acid derivative from marine sponge Haliclonasp. Chemistry of Natural Compounds 2009, 45(1), 137-138.2
Yang B, Dong J, Zhou X, Yang X, Lee K, Wang L, Zhang S, Liu Y*. Proline-containing dipeptides from the marine sponge a Callyspongiaspecies. Helvetica Chimica Acta 2009, 92, 1112-1117.8
Zhou X, Xu T, Wen K, Yang X, Xu S, Liu Y*. A new N-acyl taurine from the sea urchin Glyptocidaris crenularis. Bioscience, Biotechnology and Biochemistry 2009, 74(5), 1089-1091.7
Liu Y*, Wang L, Jung J, Zhang S. Sesterterpenoids.Natural Product Reports2007, 24(6), 1401-1429.26
Liu Y*, Zhang S, Abreu P. Heterocyclic terpenes: linear furano-and pyrroloterpenoids. Natural Product Reports2006, 23(4), 630-651.17
Liu Y, Abreu P. Tirucallane triterpenes from the roots of Ozoroa insignis. Phytochemistry2006, 67, 1309-1315.6
Liu Y, Mansoor T,Hong J, Lee C, Sim C, Im K, Jung J. New cytotoxic sesterterpenoids and norsesterterpenoids from two sponges of the genusSarcotragus.Journal of Natural Products2003, 66(11), 1451-1456.6
Liu Y, Hong J, Lee C, Im KS,Kim N, Choi J, Jung J. New cytotoxic furano- and pyrroloterpenoids from the sponge Sarcotragusspecies.Journal of Natural Products2002, 65(9), 1307-1314.4
Liu Y, Bae B, Alam N, Hong J, Sim C, Lee C, Im K,Jung J. New cytotoxic sesterterpenes from the sponge Sarcotragusspecies. Journal of Natural Products2001, 64(10), 1301-1304.5
Tao H, Wang L, Cui Z, Zhao D, Liu Y*.Dimeric proanthocyanidins from rootsof Ephedra sinicaStapf. Planta Medica2008, 74, 1823-1825. 4
Liu Y, Lee C, Hong, J, Jung J. Cyclitol derivatives from the sponge Sarcotragusspecies.Bulletin of the Korean Chemical Society2002, 23(10), 1467-1469(ChemInform Abstract).1
Liu Y*, Jung J, Zhang S. Linear pyrrolosesterterpenes from a sponge Sarcotragusspecies. Biochemical Systematics and Ecology2006, 34, 774-776.1
Park Y,Liu Y, Hong J, Lee C,Cho H, Kim D, Im K, Jung J. New bromotyrosine derivatives from an association of two sponges,Jaspis wondoensisand Poecillastra wondoensis.Journal of Natural Products2003, 66(11), 1495-1498.14
Wang L, Zhao D, Cheng D, Liu Y*. ent-Sauchinone from Saururus chinensis.Heterocycles2008, 75(5), 1241-1246.4
Wang W, Li F, Alam N, Liu Y, Hong J, Lee C, Jung J.New saponins from the starfish Certonardoa semiregularis.Journal of Natural Products2002, 65(11), 1649-1656.3
Liu Y*, Jung J, JiH, ZhangS. Glycerolipids from a Sarcotragusspecies sponge.Molecules2006, 11, 714-719.4
Liu Y*, Ji H, Zhang S, Jung J, Xu T. Trisoxazole macrolides from the sponge Sarcotragusspecies. Chemistry of Natural Compounds 2008,44(1), 140-141.1
Abreu P. Liu Y, Ozoroalide, a new macrolide from Ozoroa insignis. Fitoterapia2007, 78, 388-389.0
Yin H, Zhang S, Luo X, Liu Y. Preparative isolation and purification of two benzoxazinoid glucosides from Acanthus ilicifolius L. by high-speed counter-current chromatography. Journal of Chromatography A2008, 1205, 177-181.11
Wang L, Zhao D, Liu Y*.Quality assessment of Veratrum nigrumL. by LC-ELSD fingerprints and LC quantitative analysis. Chromatographia2008, 68, 961-967. 1
Liu Y*, Murakami N, Wang L, Zhang S. Preparative high-performance liquid chromatography for the purification of natural acylated anthocyanins from red radish (Raphanus sativusL). Journal of Chromatographic Science2008, 46(8), 743-746.4
Liu Y*, Ji H, Dong J, Zhang S. Lee K, Matthew S.Antioxidant alkaloid from South China Sea marine sponge Iotrochotasp.Zeitschrift Fur Naturforschung 2008, 63c, 636-638.6
Wang L, Li W, Liu Y*. Hypotensive effect and toxicology of total alkaloids and veratramine from roots and rhizomes of Veratrum nigrumL. in spontaneously hypertensive rats. Pharmazie2008, 63(8), 606-610.3
Jiang S, Li X, Zhang L, Sun W, Dai S, Xie L, Liu Y, Lee K. Culturable actinobacteria isolated from marine sponge Iotrochotasp. Marine Biology2008, 153(5), 945-952.15
Jiang S, Sun W, Chen M, Dai S, Zhang L, Liu Y, Lee K, Li X. Diversity of culturable actinobacteria isolated from marine sponge Haliclonasp.Antonie Van Leeuwenhoek International Journal of General and Molecular Microbiology2007, 92(4), 405-416.41
Liu Y*, Ji H, Zhang S, Murakami N, Xu T. Structure-activity relationships of1'- acetoxychavicol acetate homologues as new nuclear export signal inhibitors.Pharmazie2007, 62(9), 659-662.Die Pharmazie-An International Journal of Pharmaceutical Sciences.1
Liu Y*, Zhang S, Jung J, Xu T. Variabilin, a chemotaxonomic marker for the familly Irciniidae. Zeitschrift Fur Naturforschung2007, 62c, 473-476.1
Jung J, Shinde P, Hong J, Liu Y, Sim C. Secondary metabolites from a marine sponge Discodermia calys. Biochemical Systematics and Ecology 2007, 35, 48-51.4
Liu Y*, Murakami N, AbreuP, Ji H, Zhang S. Antimalarial flavonol glycosides from Euphorbia hirta. Pharmaceutical Biology2007, 45(4), 278-281.12
Liu Y*, Jung J, Zhang S. An unsaturated ω-hydroxy methyl ester from a sponge Sarcotragusspecies. Chemistry of Natural Compounds2006, 42(4), 487-488.0
Liu Y, Abreu P.Long chain alkyl and alkenyl phenols from Ozoroa insignis. Journal of the Brazilian Chemical Society2006, 17(3), 527-536.5
Liu Y*, Jung J, Zhang S. Indole alkaloids from a sponge Sarcotragusspecies. Biochemical Systematics and Ecology2006, 34(5), 453-456.2
Liu Y, Shinde PB, Hong J, Lee C-O, Im KS, Jung JH. Trisoxazole macrolide from a marine spongeSarctragusspecies. Natural Product Sciences2005, 11(1), 50-53.
Zhao Q, Liu Y, Hong J, Lee C-O, Park JH, Lee DS, Jung JH. A new cyclitol derivatives from a spongeStellettaspecies. Natural Product Sciences2003, 9(1), 18-21.
奖励(1) 海南省科技进步奖,一等奖,省级,2010,第15名
(2) 热带海洋生物活性物质的利用技术,二等奖,国家级,2007 第11名
(3) 吉林省科技进步奖,二等奖,省级,2011,第3名
课题组成员杨献文副研究员
周雪峰副研究员
林秀萍助理研究员
杨斌助理研究员
刘娟助理研究员
廖升荣助理研究员
王俊峰助理研究员
专利与奖励
奖励信息(1) 麻黄根等三种药材药效物质基础及制剂-麻黄根总黄酮胶囊的研究, 二等奖, 省级, 2016(2) 小飞蓬等10种药材药效活性物质基础及制剂“小飞蓬胶囊”的研究, 二等奖, 省级, 2015(3) 海洋极端微生物抗附着活性物质及其在涂料中的应用, 一等奖, 其他, 2014(4) 赤苞等4种药材药效活性物质基础及制剂赤苞乳疾康胶囊的研究, 二等奖, 省级, 2014(5) 第三届广州科技创新联盟南山奖, , 市地级, 2014(6) 第六届“全国优秀科技工作者”, , 国家级, 2014(7) 三白草等5种药材药效活性物质基础及制剂"消肝纤胶囊"的研究, 二等奖, 省级, 2011(8) 海南省科技进步奖, 一等奖, 省级, 2010(9) 热带海洋生物活性物质的利用技术, 二等奖, 国家级, 2007
专利成果( 1 ) 一种二聚黄酮化合物及其制备方法和抗癌应用, 发明, 2010, 第 1 作者, 专利号: ZL6.3( 2 ) 一种治疗高血压的海洋药物及其制备方法和分散片 , 发明, 2009, 第 1 作者, 专利号: ZL6.0 ( 3 ) 一种海胆提取物及其制备方法和抗癌应用, 发明, 2010, 第 1 作者, 专利号: ZL4.4( 4 ) 1.西松烷型二萜flexibilide或其可药用盐在制备PGC-1α抑制剂中的应用, 发明, 2012, 第 5 作者, 专利号: 2012( 5 ) 一种来源于海绵的甾醇及其制备方法和应用, 发明, 2013, 第 2 作者, 专利号: ZL9.2( 6 ) 一种罗氏海盘车提取物在制备抗肿瘤药物中的应用, 发明, 2014, 第 1 作者, 专利号: ZL5.1( 7 ) 一种来源于海绵的甾醇及其制备方法和应用, 发明, 2014, 第 2 作者, 专利号: ZL9.2( 8 ) 一种新的链霉倍半萜三醇A及其制备方法和应用, 发明, 2014, 第 5 作者, 专利号: CN8.7( 9 ) Strepsequitriol, preparation method thereof, and application thereof, 发明, 2017, 第 5 作者, 专利号: US **B2
出版信息PangX,Lin X,Tian Y,Liang R,Wang J,Yang B,ZhouX,Kaliyaperumal K,Luo X,Tu Z, Liu Y*.Three new polyketides from the marine sponge-derived fungus Trichodermasp. SCSIO41004.Natural Product Research, 2018, 32(1), 105-111.
PangX,Lin X,Wang J, Liang R,Tian Y, SalendraL, Luo X,ZhouX,Yang B,Tu Z, Liu Y*.Three new highly oxygenated sterols and one new dihydroisocoumarin from the marine sponge-derived fungus Cladosporium sp . SCSIO41007. Steroids, 2017, doi.org/10.1016/j.steroids.2017.12.001.
Lei H, Lin X, Han L, Ma J, Dong K, Wang X, Zhong J, Mu Y, Liu Y, Huang X*. Polyketide derivatives from a marine-sponge-associated fungus Pestalotiopsis heterocornis. Phytochemistry, 2017, 142, 51-59.
Lin X,Li K, Yang L,Peng X, Fang W,Tian X,Liu Y,Zhou X.Dereplication and targeted isolation of bioactive sulphur compound from bacteria isolated from a hydrothermal field. Natural Product Research, 2017, DOI:10.1080/**.2017.**
JuZ, LinX,LiM,Wangy, TianY, WangJ, LiuJ, TuZ,XuS*,LiuY*. Chaetochromones A-C, Three New Polyketides from Mangrove Plant Derived Endophytic Fungus Phomopsissp. SCSIO 41006. Chemistry & Biodiversity, 2017,14(11), doi: 10.1002/cbdv..
Li P,Liu X,Zhu H,Tang X,Shi X,Liu Y*, Li G*. Unusual Inner-Salt Guaiazulene Alkaloids and bis-Sesquiterpene from the South China Sea Gorgonian Muriceides collaris. Scientific Reports, 2017, 7, 7697. DOI:10.1038/s41598-017-08100-z
Lin X, Wu Q, Yu Y, Liang Z, Liu Y, Zhou L*, Tang L*, Zhou X*. Penicilliumin B, a novel sesquiterpene methylcyclopentenedione from a deep sea-derived Penicillium strain with renoprotective activities.Scientific Reports, 2017, accept.
LiY,Wang J,He W,Lin X,Zhou X,Liu Y*.One Strain-Many Compounds Method for Production of Polyketide Metabolites Using the Sponge-Derived Fungus Arthrinium arundinisZSDS1-F3, Chemistry of Natural Compounds, 2017, 53(2), 373-374.
Lei H,Lin X,Han L,MaJ,Ma Q,Zhong J,Liu Y,Sun T,Wang J,Huang X.New Metabolites and Bioactive Chlorinated Benzophenone Derivatives Produced by a Marine-Derived Fungus Pestalotiopsis heterocornis. Marine Drugs,2017, 15(3), DOI:10.3390/md**
Luo X,Lin X,Salendra L,Pang X,Dai Yu,Yang Bin,LiuJuan,Wang J,Zhou X*,Liu Y*.Isobenzofuranones and Isochromenones from the Deep-Sea Derived Fungus Leptosphaeria sp. SCSIO 41005. Marine Drugs,2017, 15(7),DOI:10.3390/md**
Wang J,Liang R,Liao S,Yang B,Tu Z,LinX,Wang B,Liu Y*.Vaccinols J-S, ten new salicyloid derivatives from the marine mangrove-derived endophytic fungus Pestalotiopsis vaccinii.Fitoterapia, 2017, 120,164-170
Wang J,He W,Kong F,TianXP,Wang P, Zhou X,Liu Y*.Ochracenes A-I, Humulane-Derived Sesquiterpenoids from the Antarctic Fungus Aspergillus ochraceopetaliformis.Journal of Natural Products,2017, 6, 1725-1733.
Wang L, Wang J, Liu J, Liu Y*. Antitubercular Marine Natural Products. Current Medicinal Chemistry, 2017, 24, DOI:10.2174/6**1.
Luo X, Zhou X, Lin X, Qin X, Zhang T, Wang J, Tu Z, Yang B, Liao S, Tian Y, Pang X, Kaliyaperumal K, Li JL, Tao H, Liu Y*. Antituberculosis compounds from a deep-sea-derived fungus Aspergillus sp. SCSIO Ind09F01.Natural Product Research, 2017, 31(16), 1958-1962.
Liao SR,Tang Y,Xu L,Zhou XF,Wang JF, Yang B,Liu Y*. Ring-contraction from benzo[b][1,4]thiazines to benzo[d]thiazolines induced by oxygen. Tetrahedron2017, 73(1), 98-107.
Xian J, Lin X,Lu X, Wan J, Wang J, Zhou X, Ai W, Tu Z, LiuY*. Pestalachloride E, a new chlorinated benzophenone derivative from mangrove endophytic fungus Pestalotiopsis versicolor. Chinese Journal of Antibiotics2017,42, 8-13.
YangB,TaoH,QinX,WangZ,DongJ,LinX,ZhouX,LiJ,TuZ, LiuY*. Aspergone, a new chromanone derivative from fungus Aspergillussp. SCSIO41002 derived of mangrove soil sample. The Journal of Antibiotics2017, 6,788-790.
Chen S, Wang J, Wang Z, Lin X, Zhao B, Kaliaperumal K, Liao X, Tu Z, Li J, Xu S, Liu Y*.Structurally diverse secondary metabolites from a deep-sea-derived fungus Penicillium chrysogenum SCSIO 41001 and their biological evaluation. Fitoterapia, 2017, 17, 71–78.
He WJ, Zhou XJ, Qin XC, Mai YX, Lin X, Liao S, Yang B, Zhang T, Tu Z, Liu Y.* Quinone/hydroquinone meroterpenoids with antitubercular and cytotoxic activities produced by the sponge-derived fungus Gliomastix sp. ZSDS1-F7. Natural Product Research2017, 31(5), 604-609.
Wang JF, Qin XC, Chen Z, Ju Z, He W, Tan Y, Zhou XJ, Tu ZC,Lu F*,Liu Y*.Two new anthraquinones with antiviral activities from the barks of Morinda citrifolia(Noni).Phytochemistry Letters, 2016, 15, 13-15.
Zhao BQ,Peng S,He WJ,Liu YH,Wang JF, Zhou XJ. Antitubercular and cytotoxic tigliane-type diterpenoids from Croton tiglium. Bioorganic & Medicinal Chemistry Letters, 2016, 26(20), 4996–4999.
Kim A, Kim MJ, Noh TH, Hong J, Liu Y, Wei XY, Jung JH*.Synthesis and antibacterial evaluation of hamacanthin B analogues.Bioorganic & Medicinal Chemistry Letters, 2016, 26(20), 5013–5017.
Kim EL, Li J, Hong, J, Yoon WD, Kim HS, Liu Y, Wei X, Jung JH*.An unusual 1(10-19)abeosteroid from a jellyfish-derived fungus. Tetrahedron Letters,2016, 57(25), 2803-2806.
Wang H, Hong J, Yin J, Liu J, Liu Y, Choi JS, Jung, JH*.Paecilonic Acids A and B, Bicyclic Fatty Acids from the Jellyfish-Derived Fungus Paecilomyces variotii J08NF-1. Bioorganic & Medicinal Chemistry Letters, 2016, 26(9), 2220-2223.
XuG, Wang Z, Zhao B, Liu N, Yang S, Liu Y, Wang J*, Zhou X.*Saniculamins A and B, two new flavonoids from Sanicula lamelligera Hance inhibiting LPS-induced nitric oxide release.Phytochemistry Letters 2016, 18, 35-38.
LiuJ, JungJH, Liu Y.*Antimicrobial compounds from marine invertebrates-derived microorganisms.Current Medicinal Chemistry, 2016, 23(25): 2892-2905.
Chen S, Wang J, Lin X, Zhao B, Wei X, Li G, Kaliaperumal K, Liao S, Yang B, Zhou X, Liu J, Xu S, Liu Y*. Chrysamides A-C, three dimeric nitrophenyl trans-epoxyamides produced by the deep-sea-derived fungus Penicillium chrysogenum SCSIO41001. Organic Letters, 2016, 18, 3650-3653.
Liao S,Qin X,Wang Z, Li D,Xu L,Li J,Tu Z, Liu Y*Design, synthesis and cytotoxic activities of novel 2,5-diketopiperazine derivatives. European Journal of Medicinal Chemistry, 2016, 121, 500-509.
Wang J,Wei X,Qin X,TianX,Liao L,Zhou X,YangX, Wang F, Tu Z,Chen B,Liu Y.* Antiviral merosesquiterpenoids produced by an antarctic fungus Aspergillus ochraceopetaliformis SCSIO 05702. Journal of Natural Products, 2016, 79(1), 59-65.
WangJ,HeW, HuangX, TianX,LiaoS, YangB,WangF, ZhouX,LiuY*Antifungal new oxepine-containing alkaloids and xanthones fromthe deep-sea-derived fungus Aspergillus versicolorSCSIO 05879.JournalofAgriculture andFood Chemistry2016, 64, 2910-2916.
ZhouX,FangW, TanS, LinX, XunT,YangB,LiuS,LiuY.*Aspernigrins with anti-HIV-1 activities from the marine-derived fungus Aspergillus niger SCSIO Jcsw6F30. Bioorganic & Medicinal Chemistry Letters, 2016, 26, 361-365.
Tian Y,Lin X, Wang Z, Zhou X, Qin X, Kaliyaperumal K, Zhang T,Tu Z,Liu Y.*Asteltoxins with antiviral activities from themarine sponge-derived fungus Aspergillussp.SCSIO XWS02F40.Molecules,2016, 21(1), 34,doi:10.3390/molecules**
LiaoS ,Du L,QinX, XuL,WangJ,Zhou X, TuZ,LiJ*,LiuY*. Siteselective synthesis of cytotoxic 1,3,6-trisubstituted 3,6-diunsaturated (3Z,6Z)-2,5-diketopiperazines via a one-pot multicomponent method. Tetrahedron, 2016,72(8), 1051-1057.
Asperpyrone-Type Bis-Naphtho--Pyrones with COX-2-Inhibitory Activities from Marine-Derived Fungus Aspergillus niger. Fang W, Lin X, Wang J, LiuY, Tao H, Zhou X.MOLECULES, 2016, 21(7), DOI:10.3390/molecules**.
Ju ZR,Qin XC, Lin XP,Wang JF,Kaliyaperumal K,Tian YQ,Liu J,Liu F,Tu ZC,Xu SH,Liu Y*.New phenyl derivatives from endophytic fungus Botryosphaeria sp SCSIO KcF6 derived of mangrove plant Kandelia candel. Natural Product Research, 2016, 30(2), 192-198.
YangB, HuangJ, LinX, ZhangY, Tao H, Liu Y*. Anew diketopiperazine from the marine sponge Callyspongiaspecies. Records of Natural Products, 2016, 10 (1), 117-121.
Yang B, Huang J, Li X, Lin X, Zhou X, Tao H, Liu Y*. Isolation, Characterization, and Bioactivity Evaluation of Alkaloids from Soft Coral Sinularia kotanianensis. Chemistry of Natural Compounds, 2016,52(3),564-566.
Tao G, Liu J, Jung JH, Guo W, Wen XQ, LiuY*. Compounds from a jellyfish-derived fungus Aspergillus fumigates. Natural Product Sciences, 2016,22(2):82-86.
Wang H,Hong J,Yin J,Moon HR,Liu Y,Wei X,Oh DC,Jung JH*. Dimeric Octaketide Spiroketals from the Jellyfish-Derived Fungus Paecilomyces variotii J08NF-1.J Nat Prod.2015,78(11):2832-2836.
WangJ, WeiX, QinX, LinX, ZhouX, LiaoS,YangB,LiuJ, TuZ,LiuY*.Arthpyrones A–C, Pyridone alkaloids from a sponge-derived fungus Arthrinium arundinisZSDS1-F3. Organic Letters, 2015, 17,656?659.
LiaoS, XuY,TangY,WangJ, ZhouX,XuL,LiuY*. Design, synthesis and biological evaluation of soluble 2,5-diketopiperazines derivatives as potentialantifouling agents.RSC Advances2015, 5, 5, 51020–51026
Wang JF, He WJ, Qin XC, Wei XY, Tian XP,Liao L, Liao SR, Yang B, Tu ZC,Chen B,Wang FZ,Zhou XJ,Liu Y*.Three new indolyl diketopiperazine metabolites from the antarctic soil-derived fungus Penicillium sp SCSIO 05705. RSC Advances, 2015, 5(84), 68736-68742.
ZhangJ,LinX, LiL,ZhongB, LiaoX, LiuY*, XuS*Gliomasolides A–E, unusual macrolides from asponge-derived fungus Gliomastixsp. ZSDS1-F7-2? RSC Advances2015, 5, 54645–54648
BaiZ,LinX,WangJ, ZhouX,LiuJ, YangY, YangX, Liao S,Wang L, LiuY.*Newmeroterpenoidsfrom the endophytic fungus Aspergillus flavipes AIL8 derived fromthe mangrove plant Acanthus ilicifolius. Marine Drugs, 2015, 13, 237-248.
Liu J, Wei X, Kim E, Lin X, Yang X, Zhou X, Yang B, Jung J, Liu Y.*New glucosidated pyrazinoquinazoline indole alkaloids from fungus Aspergillus fumigatus derived of a jellyfish. Tetrahedron, 2015, 71, 271-275.
Wang J, Wang Z, Ju Z, Wan J, Liao S,Lin X, Zhang T, Zhou X,Chen H, Yang B, Tu Z,Liu Y.*Cytotoxic cytochalasins from marine-derived fungus Arthriniumarundinis ZSDS1-F3. PlantaMedica, 2015, 81, 160-166.
Li J, Huang L, Liu J, Song Y, Gao J, Jung J,Liu Y*, Chen G*. Acetylcholinesterase inhibitory dimeric indole derivatives from the marine actinomycetes Rubrobacter radiotolerans, Fitoterapia2015, 102, 203-207.
Wang JF, Yang SH, Liu YQ, Li DX,He WJ, Zhang XX,Liu Y*,Zhou XJ*.Five new phorbol esters with cytotoxic and selective anti-inflammatory activites from Croton tiglium. Bioorganic & Medicinal Chemistry Letters, 2015, 25(9), 1986-1989.
Wang L,Wang J,Wang L, Ma S, LiuY.*Anti-enterovirus 71 agents of natural products. Molecules2015, 20(9), 16320-16333.
Qin C, Lin X, Lu X, Wan J, Zhou X, Liao S, Tu Z, Xu S, Liu Y.*Sesquiterpenoids and xanthones derivatives produced by sponge-derived fungus Stachybotrysp. HH1 ZSDS1F1-2.The Journal of Antibiotics2015,68, 121-125
Ai W, Lin L, Wang Z, Lu X, Mangaladoss F, Yang X,Zhou X, TuZ, Liu Y.* Cladosporone A, a new dimeric tetralone from fungus Cladosporium sp. KcFL6’ derived of mangrove plant Kandelia candel.The Journal of Antibiotics2015, 68, 213-215.
Tian Y,Qin X,Lin X,KumaravelK,Zhou X,Liu J,Ju Z,Tu Z,Liu Y.*Sydoxanthone C and acremolin B produced by deep-sea-derived fungus Aspergillus sp. SCSIO Ind09F01. The Journal of Antibiotics2015, 68, 703-706.
Ju ZR,Lin XP,Lu X,Tu ZC,Wang JF,Kaliyaperumal K,Liu J, Tian YQ,Xu SHLiu Y.*Botryoisocoumarin A, a new COX-2 inhibitor from the mangrove Kandelia candel endophytic fungus Botryosphaeria sp KcF6.The Journal of Antibiotics2015, 68, 653-656.
Ai W, Lin X, Tu Z, Tian X, Lu X, Mangaladoss M, Zhong J, Liu Y.*Axinelline A, a new COX-2 inhibitor fromStreptomyces axinellaeSCSIO02208. Natural Product Research 2015, 68, 213-215.
Tian Y, LinX, Liu J, Kaliyaperumal K, Ai W, Ju J, Yang Y, Wang J, Yang X,LiuY.*Ascomycotin A, a new citromycetin analogue produced by Ascomycota sp. Ind19F07 isolated from deep sea sediment.Natural Product Research 2015,29(9), 820-826.
Sun J, Yang B, Zhou X, Yang X, Wang L, Liu Y.*A new briarane-type diterpenoid from the South China Sea Gorgonian Dichotella gemmacea. Natural Product Research 2015,29(9), 807-812.
Fredimoses M, Zhou X, Ai W, Tian X, Yang B, Lin X, Xian J, Liu Y.* Westerdijkin A, a new hydroxyphenylacetic acid derivative from deep sea fungus Aspergillus westerdijkiae SCSIO 05233.Natural Product Research 2015, 29(2), 158-162.
Wang J, Qin X, Xu F, Zhang T, Liao S, Lin X, Yang B, Liu J, Wang L, Tu Z, Liu Y*.Tetramic acid derivatives and polyphenols from sponge-derived fungus and their biological evaluation. Natural Product Research2015, 29(18), 1761-1765.
Yang B,Huang JX,Lin XP,Liao SR,Zhou XF, Liu J,Wang JF, Wang LS, Liu Y*. New casbane diterpenoids from the Hainan soft coral Sinulariaspecies. Helvetica Chimica Acta, 2015, 98(6), 834-841.
Wang, JF,Wei XY, Qin XC, Chen H,Lin XP,Zhang TY, Yang XW, Liao SR, Yang B,Liu J,Zhou XF,Tu ZC, Liu Y*.Two new prenylated phenols from endogenous fungus Pestalotiopsis vaccinii of mangrove plant Kandelia candel (L.) Druce. Phytochemistry Letters, 2015, 12, 59-62.
Huang, RM,Chen, YN,Zhou, XF, Yang, XW, Liu, Y*. A new N-Acyl taurine from the South China Sea marine sponge Callyspongia sp.Chemistry of Natural Compounds, 2015, 51(3), 540-541.
SunJ,WuY, YangB, LiuY.*Chemical constituents of marine sponge Halichondria sp.from South China Sea.Chemistry of Natural Compounds2015, 51(5), 975-977.
WangH, HongJ, YinJ, MoonH, LiuY, WeiX, OhD, JungJH. Dimeric Octaketide spiroketals from the jellyfish-derived fungus Paecilomyces variotii J08NF-1, Journal of Natural Products, 2015, 78(11), 2832-2836.
YangX,MiaoZ,MaX, ZhangG, Steinmetz A,Yang B,Wang J,Liu J, Liu Y, WangN. Asterolloside, a novel enolic saccharide from the sea star Asterias rollestoniBell. Tetrahedron Letters, 2015, 56,6174-6176.
Wang J, He W,Zhang X, Zhao B, Liu Y,Zhou X*. Dicarabrol, a new dimeric sesquiterpene from Carpesiumabrotanoides L. Bioorganic & Medicinal Chemistry Letters, 2015, 25, 4082-4084.
Wang B, Wang L, Li Y, Liu Y*. Heterocyclic terpenes: linear furano-and pyrroloterpenoids. RSC Advances2014,4, 12216-12234.
Lei H, Sun S, Han Z, Zhou X, Yang B, Liu Y*. Fragilisinins A-L, new briarane-type diterpenoids from gorgonianJunceella fragilis. RSC Advances 2014,4(10), 5261-5271.
Wang L, Zhou X, Fredimoses M, Liao S, Liu Y*. Naturally occurring organoiodines, RSC Advances2014, 4 (101), 57350- 57376.
Fredimoses M, Zhou X, Lin X, Tian X, Ai W, Wang W, Liao S, Liu J, Yang B, Yang X, Liu Y.*New prenylxanthones from the deep-sea derived fungus Emericellasp. SCSIO 05240.Marine Drugs2014, 12(6), 3190-3202.
Yang B,Wei X,Huang J,Lin X,Liu J,Liao S,Wang J,Zhou X,Wang L,Liu Y*. Sinulolides A-H, New Cyclopentenone and Butenolide Derivatives from Soft Coral Sinularia sp. Marine Drugs, 2014, 12(10), 5316-5327.
Liao S, Qin X, Li D, Tu Z, Li J, Zhou X, Wang J, Yang B, Lin X, Liu J, Yang X, Liu Y*. Design and synthesis of novel soluble 2,5-diketopiperazine derivatives as potential anticancer agents. European Journal of Medicinal Chemistry, 2014, 83, 236-244.
72.Yang B, Dong J, Lin X, Zhou X, Zhang Y, Liu Y*. New prenylated indole alkaloids from fungus Penicillium sp. derived of mangrove soil sample. Tetrahedron, 2014, 70(25), 3859–3863. Ai W, Wei X, Lin X,Sheng L, Wang Z, Tu Z, Yang X,Zhou X, Li J, Liu Y.*Guignardins A-F, spirodioxynaphthalenes from the endophytic fungus Guignardia sp KcF8 as a new class of PTP1B and SIRT1 inhibitors. Tetrahedron, 2014, 70(35), 5806-5814.
Wang J, Wei X, Lu X,Xu F, Wan J, Lin X, Zhou X,Liao S,Yang B, Tu Z, Liu Y.*Eight new polyketide metabolites fromthe fungus Pestalotiopsis vaccinii endogenous with the mangrove plant Kandelia candel (L.) Druce. Tetrahedron, 2014,70, 9695-9701.
Fang W, Lin X, Zhou X, Ai W, Lin J. Yang B, Tu C, Liu Y.*Cytotoxic and antiviral sesquiterpenoid nitrobenzoyl esters from the marine-derived fungus Aspergillus sp. Jcma1F17.MedChemComm 2014, 5, 701-705.
Bai Z, Lin X, Wang Y, Wang J, Zhou X, Yang B, Liu J, Yang X, Wang Y, Liu Y* New phenyl derivatives from endophytic fungus Aspergillus flavipes AIL8 derived of mangrove plant Acanthus ilicifolius. Fitoterapia, 2014, 95, 194-202.
Sun J, Lin X, Zhou X, Wan J, Zhang T, Yang B, Yang X, Tu Z, Liu Y*. Pestalols A-E, New AlkenylPhenoland Benzaldehyde Derivatives from Endophytic Fungus Pestalotiopsis sp. Acbc2 Isolated from the Chinese Mangrove Plant Aegiceras corniculatum. The Journal of Antibiotics 2014, 67(6), 451-457.
Wang J, Lin X, Qin Z, Liao S, Wan J, Zhang T, Liu J, Fredimoses M, Chen H, Yang Y, Zhou X, Yang X, Tu Z, Liu Y*. Antimicrobial and Antiviral Sesquiterpenoids from Sponge-Associated Fungus, Aspergillus sydowiiZSDS1-F6.The Journal of Antibiotics2014, 67(8), 581-583.
Liao S, Qin C,Yao P, Li J, Zhou X,Wang J, Huang Z, Liu Y.*A One-PotSynthesis of Unsaturated, Polysubstituted 3-Aminoazepan-2-ones. Synthesis 2014, 46(5), 621-628.
Yang X, Li S, Li Y, Feng L, Shen Y, Lin S, Tian J, Zeng H, Wang N, Steinmetz A, Liu Y, Zhang W. Chemical constituents of Abies delavayi.Phytochemistry, 2014, 105, 164-170.
Peng Y, Huang R, Hu J, Zhou X, Yang B, Liu L, Yang X, Liu Y*. Bioactive chemical constituents of the South China Sea starfish Stellaster equestris. Chemistry of Natural Compounds, 2014, 50(1), 184-185.
Huang R, Yan T, Peng Y, Zhou X, Yang X, Liu Y.Diketopiperazines from the marine spongeAxinellasp. Chemistry of Natural Compounds, 2014, 50(1), 191-193.
Wang J, Xu F, Wang Z, Lu X, Wan J, Yang B, Zhou X, Zhang T, Tu Z, Liu Y*A new naphthalene glycoside from the sponge-derived fungus Arthrinium arundinisZSDS1-F3. Natural Product Research2014, 28(14), 1070-1074.
Yang B, Dong J, Lin X, Tao H, Zhou ZLiu Y.Xylaolide A, a new lactonefrom the fungusXylariaceaesp. DPZ-SY43. Natural Product Research 2014,28(13), 967-970.
Zhou X, Sun J, Ma W, Fang W, Chen Z, Yang B, Liu Y*. A new aromatic amine from fungus Pestalotiopsis vaccinii. Phytochemistry Letters2014, 7, 35-37.
Zhou X, Sun J, Ma W, Fang W, Chen Z, Yang B, Liu Y*. Bioactivities of six sterols isolated from marine invertebrates. Pharmaceutical Biology2014, 52(2), 187-190.
Yang B,Tao H, Zhou X,Lin X, Liu Y*.Two new alkaloids from marine sponge Callyspongia sp.Natural ProductResearch2013, 27(4-5),433-437.
Wang L, Yang B, Lin X, Zhou X, Liu Y*. Sesterterpenoids, Natural Product Report2013, 30, 455-473.
Yang B, Liao S, Lin X, Wang J, Liu J, Zhou X, Yang X, Liu Y*. New Sinularianin Sesquiterpenes from Soft CoralSinulariasp.Marine Drugs, 2013, 11, 4747-4750.
Yang X, Peng K, Liu Z, Zhang G, Li J, Wang N,Steinmetz A, Liu Y. Strepsesquitriol, a Rearranged Zizaane-Type Sesquiterpenoid from the Deep-Sea-Derived Actinomycete Streptomycessp. SCSIO 10355.Journal of Natural Product 2013, 76, 2360-2363.
Sun J, Han Z, Zhou X, Yang Y, Lin X, Liu J, Peng Y, Yang X, Liu Y*. Antifouling briarane type diterpenoids from South China Sea gorgonians Dichotella gemmacea, Tetrahedron2013, 69, 971-880.
Zhou X, Liu J,Yang B, Lin X, Yang X, Liu Y*. Marine Natural Products with Anti-HIV Activities in the Last Decade, Current Medicinal Chemistry2013, 20(7), 953-973.
Yang X, Zhang G, Ying J, Yang B, Zhou X, Steinmetz A, Liu Y*. Wang N.Isolation, characterization, and bioactivity evaluation of 3-((6-methylpyrazin-2-yl) methyl)-1H-indole, a new alkaloid from a deep-sea-derivated actinomycete Serinicoccus profundi sp. nov. Marine Drugs 2013, 11, 33-39.
Huang RM, Peng Y, Zhou XF, Yang X, Liu Y*. A new taurine derivative from South China Sea marine sponge Axinellasp.Natural Product Research2013, 27(17),1537-1541.
Huang RM, Peng Y, Zhou XF, Fu MQ, Tian S, Liu Y*. A new pyrimidinedione derivative from the gorgonian coral Verrucellaumbraculum.Natural Product Research2013, 27(4-5),319-322.
Zhou X, Lin X, Guo X, Yang Y, Yang X, Liu Y*. Chemical Constituents of the Sponge Mycale Species from South China Sea, Records of Natural Products2013, 7, 119-123.
Yang B, Zhou X, Huang H, Yang X, Liu J, Lin X, Li X, Peng Y, Liu Y*.New cembrane diterpenoids from a Hainan soft coral Sinularia sp. Marine Drugs 2012, 10, 2023-2032.
Yang B, Zhou X, Lin X, Liu J, Peng Y, Yang X,Liu Y*. Cembrane diterpenes chemistry and biological properties. Current Organic Chemistry2012, 16(12), 1512-1539.
ChenJ, Lan X, LiuY*, Jia A.In vitroeffects of natural diketopiperazines on release of cytokines and chemokines in J774A.1 macrophages. Bioorganic Medicinal ChemistryLetter 2012, 16, 3177-3180.
Lin X, Zhou X, Wang F, Liu K, Yang B, Yang X, Peng P, Liu L, Ren Z,Liu Y*. A new cytotoxic sesquiterpene quinone produced by Penicilliumsp. F00120 isolated from a deep sea sediment sample. Marine Drugs 2012, 10, 106-115.
Kim E, Li J, Dang H, Hong J, Lee C, Kim D, Yoon W, Kim E, Liu Y, Jung J.Cytotoxic cytochalasins from the endozoic fungus Phoma sp. of the giant jellyfish Nemopilema nomurai. Bioorganic & Medicinal Chemistry Letters2012, 22, 3126–3129.
Li W, Wang L, Zhao D, Liu Y*. Steroidal alkaloids from Veratrum nigrumL.Chemistry of Natural Compounds2012, 48(5), 919-920.
He WH, Lin L, Xu T, Jung JH, Yin H, Yang B, Liu Y*. A new norsesterterpenoid from the sponge species Sarcotragus. Chemistry of Natural Compounds2012, 48(2), 208-210.
Peng Y, Xie E, Zheng K, Fredimoses M, Yang Y, Zhou X, Wang Y, Yang B, Lin X, Liu J, Liu Y*.Nutritional and Chemical Composition and Antiviral Activity of Cultivated Seaweed Sargassum naozhouenseTseng et Lu. Marine Drugs 2013, 11, 20-32.
Huang R, Wang B, Liu Y*. Briarane-type diterpenoids from the gorgonian coral Verrucella umbraculum. Chemistry of Natural Compounds 2012, 48(3), 516-517.
Yang B, Hu J, Lei H, Chen XC, Zhou XF, Liu Y*. Chemical constituents of marine sponge Callyspongia sp. from the South China Sea. Chemistry of Natural Compounds 2012, 48(2), 350-351.
Liao X, Tang L, Liang Y, Jian S, Xu S, Liu Y*. New pentahydroxylated steroids from the South China Sea gorgonian Subergorgia suberosaChemistry & Biodiversity2012, 9, 370-375.
Liu Y*. Renaissance of marine natural product drug discovery and development. Journal of Marine Science Research & Development2012,2, 1000e106.
Sun J, Huang H, Chai X, Yang X, Meng L, Huang C, Zhou X, Yang B, Hu J, Chen X, Lei H, Wang L, Liu Y*. Dichotellides A-E, five new iodine-containing briarane type diterpenoids from Dichotella gemmacea. Tetrahedron2011, 67, 1245-1250.
Wang L, Zhao D, Di L, Xu T, Lin X, Yang B, Zhou X, Yang X, Liu Y*. The analgesic and anti-rheumatic effects of Thladiantha dubiafruit crude polysaccharide fraction in mice and rats.Journal of Ethnopharmacology2011, 137, 1381-1387.
Zhou X, Lu Y, Lin X, Yang Y, Yang X, Liu Y.Brominated aliphatic hydrocarbons and sterols from the sponge Xestospongia testudinariawith their bioactivities Chemistry and Physics of lipids 2011,164, 703-706.
Yang X, Li Y, Li S, Shen Y, Tian J, Zhu Z, Feng L, Wu, L, Lin, S, Wang, N, Liu Y, Zhang W. Mono- and sesquiterpenoids, flavonoids, lignans, and other miscellaneous compounds of Abies georgei. Planta Medica2011, 77(7), 742-748.
WangL, ZhaoD, DiL,ChengD, ZhouX, YangX, LiuY*.The anti-hyperplasiaofmammaryglandeffectof Thladiantha dubiaroot ethanol extract inratsreducedbyestrogenandprogestogen. Journal of Ethnopharmacology2011, 134, 136-140.
Yang X, Dong G, Zhou X, Chai X, Li Y, Yang B, Zhang W, Liu Y*. Isolation and structural characterisation of five new and 14 known metabolites from the commercial starfish Archaster typicusFood Chemistry 2011, 124, 1634-1638.
Liu Y*, Yan H, Wen K, Zhang J, Xu T, Wang L, Zhou X, Yang X. Identification of epidioxysterol from South China Sea urchin Tripneustes gratillaLinnaeus and its cytotoxic activity. Journal of Food Biochemistry2011, 35, 932-938.
Hu J, Yang B, Lin X, Zhou X, Yang X, Long L, Liu Y*.Chemical and Biological Studies of Soft Corals Nephtheidae Family.Chemistry& Biodiversity2011, 8, 1011-1032.
Dong G, Yang X, Zhou X. Liu Y*.Chemical constituents and bioactivities of starfish. Chemistry & Biodiversity2011, 8(5), 740-791.
Huang R, Zhou X, Peng Y, Yang X, Xu T,Liu Y*. Nucleosides from the marine sponge Callyspongia sp. Chemistry of Natural Compounds2011, 46, 1010-1011.
Liu Y*, Jung J, Xu T, Long LJ, Lin XP, Yin H., Yang B, Zhou XF, Yang XW.New cyclitol derivative from a sponge Sarcotragus species. Natural Products Research2011, 25(6), 648-652.
Chai X, Sun J, Tang L, Yang X, Li Y, Huang H, Zhou X, Yang B, Liu Y*.A novel cyclopentene derivative and a polyhydroxylated steroid from a South China Sea gorgonian Menella sp.Cheimcal & Pharmaceutical Bulletin 2010, 58(10), 1391-1394.
Liu J, Wang L, Zhao D, Cheng D, Xu T, Zhou X, Yang X, Liu Y*. A new lignan from Saururus chinensis. Chemistry of Natural Compounds 2010, 46(4), 631-632.
Zhou X, Xu T, Yang X, Xu S, Liu Y*. Chemical and biological aspects of marine sponge of the genus Xestospongia. Chemistry & Biodiversity 2010, 7, 2201-2227.
Wang L, Zhou X, Xu T, Yang X, Liu Y*. Lignans from Saururus chinensis.Chemistry of Natural Compounds2010, 46(3), 451-452.
Peng Y, Zheng J, Huang R, Wang Y, Xu T, Zhou X, Liu Q, Zeng F, Ju H, Yang X, Liu Y*.Polyhydroxysteroids and saponins from the China Sea starfish Asterinasp. and their biological activities.Chemical & Pharmaceutical Bulletin2010, 58(6),856-858.
Zhou X,Liu Y, Tang L, Zhang P, Wu J. Chemical constituents from the roots of Actinidia chinensis.Chemistry of Natural Compounds 2010, 46(2), 308-309.
Huang L, Wen K, Gao X, Liu Y*. Hypolipidemic effect of fucoidan from Laminaria japonicain hyperlipidemic rats. Pharmaceutical Biology2010, 48(4), 422-426.
Huang R, Ma W, Dong J, Zhou X, Xu T, Lee K,Yang X, Xu S, Liu Y*. A new 1,4-diazepine from South China Sea marine sponge Callyspongia species. Molecules2010, 15, 871-877.
Yang X, Li S, Wu L, Li Y, Feng L, Shen Y, Tian J, Tang J, Wang N, Liu Y, Zhang W. Abiesatrines A-J: anti-inflammatory and anti-tumor triterpenoids from Abies georgeiOrr. Organic & Biomolecular Chemistry 2010, 8, 2609-2616.
Ren S, Ma W, Xu T, Lin X, Yin H, Yang B, Zhou X, Yang X, Long L, Lee K, Gao Q, Liu Y*. Two novel alkaloids from the South China Sea marine sponge Dysidea sp.Journal of Antibiotics 2010,63, 699-701.
Huang R, Zhou X, Xu T, Yang X, Liu Y*. Diketopiperazines from marine organisms. Chemistry & Biodiversity 2010, 7, 2809-2829.
Yang X, Li S, Li Y, Xia J, Wu L, Shen Y, Tian J, Wang N, Liu Y, Zhang W. Abiespiroside A, an Unprecedented Sesquiterpenoid Spirolactone with a 6/6/5 Ring System from Abies delavayi. European Journal of Organic Chemistry 2010, 34, 6531-6534.
Xu Y, Liu Y, Xu T, Xie S, Si Y, Liu Y, Zhou H, Liu T, Xu D. A new furostanol glycoside from Tribulus terrestris. Molecules2010,15,613-618.
Xu Y, Bai L, Liu Y, Xu T, Liu Y, Xie S, Si Y, Zhou H, Liu T, Xu D. A new triterpenoid saponin from Pulsatilla cernua.Molecules2010, 15, 1891-1897.
Lei H, Zhou X, Yang Y, Xu T, Yang X, Sun J, Yang Y, Hu J, Lin X, Long L, Liu Y*. Bryostatins from South China Sea bryozoan Bugula neritinaL. Biochemical Systematics and Ecology 2010, 38, 1231-1233.
Zhou X, Wen K, Yang X, Huang R, Dong G, Yang B, Sun J, Liu Y*. Chemical constituents from the sea urchin Glyptocidaris crenularis.Biochemical Systematics and Ecology 2010, 38, 103-105.
Yang X, Feng L, Li S, Liu X, Li Y, Wu L, Shen Y, Tian J, Zhang X, Liu X, Wang N, Liu Y, Zhang, W. Isolation, structure, and bioactivities of abiesadines A–Y, twenty-five new diterpenes from Abies georgei Orr.Bioorganic Medicinal Chemistry2010, 18, 744-754.
Wang L, Cheng D, Wang H, Di L, Zhou X, Xu T, Yang X, Liu Y*. The hepatoprotective and antifibrotic effects of Saururus chinensis against carbon tetrachloride induced hepatic fibrosis in rats. Journal of Ethnopharmacology2009, 126, 487-491.9
Wang L, Zhao D, Xu T, Zhou X, Yang X, Liu Y*. A new triterpene hexaglycoside from the bark of Kalopanax septemlobus (Thunb.) Koidz.Molecules2009, 14, 4497-4504.1
Zhou X, Tang L,Liu Y. An isomeric mixture of novel cerebrosides isolated from Impatiens pritzelliireduces lipopolysaccharide-induced release of IL-18 from human peripheral blood mononuclear cells. Lipids2009, 44(8), 759-763.2
Zhou X, Tang L, Zhang P, Zhao X, Pi H, Zhang Y, Ruan H, Liu Y, Wu J. The interleukin-18 inhibitory activities of echinocystic acid and its saponins from Impatiens pritzellii var. hupehensis. Zeitschrift Fur Naturforschung 2009, 64c, 369-372.3
Wang L, Zhao D, Liu Y*. GC-MS analysis of the supercritical CO2fluid extraction of Ephedrasinicaroots and its antisudorific activity. Chemistry of Natural Compounds 2009, 45(3), 434-436.2
Wang B, Dong J, Zhou X, Lee KJ, Huang R, Zhang S, Liu Y*. Nucleosides from marine sponges including known ones from Haliclonasp. Zeitschrift Fur Naturforschung 2009, 64c, 143-148.0
Wang B, Lee K, Zhang S, Jung J, Liu Y*. 2-Palmitamidoethanesulfonic acid, new aminoethylsulfonic acid derivative from marine sponge Haliclonasp. Chemistry of Natural Compounds 2009, 45(1), 137-138.2
Yang B, Dong J, Zhou X, Yang X, Lee K, Wang L, Zhang S, Liu Y*. Proline-containing dipeptides from the marine sponge a Callyspongiaspecies. Helvetica Chimica Acta 2009, 92, 1112-1117.8
Zhou X, Xu T, Wen K, Yang X, Xu S, Liu Y*. A new N-acyl taurine from the sea urchin Glyptocidaris crenularis. Bioscience, Biotechnology and Biochemistry 2009, 74(5), 1089-1091.7
Liu Y*, Wang L, Jung J, Zhang S. Sesterterpenoids.Natural Product Reports2007, 24(6), 1401-1429.26
Liu Y*, Zhang S, Abreu P. Heterocyclic terpenes: linear furano-and pyrroloterpenoids. Natural Product Reports2006, 23(4), 630-651.17
Liu Y, Abreu P. Tirucallane triterpenes from the roots of Ozoroa insignis. Phytochemistry2006, 67, 1309-1315.6
Liu Y, Mansoor T,Hong J, Lee C, Sim C, Im K, Jung J. New cytotoxic sesterterpenoids and norsesterterpenoids from two sponges of the genusSarcotragus.Journal of Natural Products2003, 66(11), 1451-1456.6
Liu Y, Hong J, Lee C, Im KS,Kim N, Choi J, Jung J. New cytotoxic furano- and pyrroloterpenoids from the sponge Sarcotragusspecies.Journal of Natural Products2002, 65(9), 1307-1314.4
Liu Y, Bae B, Alam N, Hong J, Sim C, Lee C, Im K,Jung J. New cytotoxic sesterterpenes from the sponge Sarcotragusspecies. Journal of Natural Products2001, 64(10), 1301-1304.5
Tao H, Wang L, Cui Z, Zhao D, Liu Y*.Dimeric proanthocyanidins from rootsof Ephedra sinicaStapf. Planta Medica2008, 74, 1823-1825. 4
Liu Y, Lee C, Hong, J, Jung J. Cyclitol derivatives from the sponge Sarcotragusspecies.Bulletin of the Korean Chemical Society2002, 23(10), 1467-1469(ChemInform Abstract).1
Liu Y*, Jung J, Zhang S. Linear pyrrolosesterterpenes from a sponge Sarcotragusspecies. Biochemical Systematics and Ecology2006, 34, 774-776.1
Park Y,Liu Y, Hong J, Lee C,Cho H, Kim D, Im K, Jung J. New bromotyrosine derivatives from an association of two sponges,Jaspis wondoensisand Poecillastra wondoensis.Journal of Natural Products2003, 66(11), 1495-1498.14
Wang L, Zhao D, Cheng D, Liu Y*. ent-Sauchinone from Saururus chinensis.Heterocycles2008, 75(5), 1241-1246.4
Wang W, Li F, Alam N, Liu Y, Hong J, Lee C, Jung J.New saponins from the starfish Certonardoa semiregularis.Journal of Natural Products2002, 65(11), 1649-1656.3
Liu Y*, Jung J, JiH, ZhangS. Glycerolipids from a Sarcotragusspecies sponge.Molecules2006, 11, 714-719.4
Liu Y*, Ji H, Zhang S, Jung J, Xu T. Trisoxazole macrolides from the sponge Sarcotragusspecies. Chemistry of Natural Compounds 2008,44(1), 140-141.1
Abreu P. Liu Y, Ozoroalide, a new macrolide from Ozoroa insignis. Fitoterapia2007, 78, 388-389.0
Yin H, Zhang S, Luo X, Liu Y. Preparative isolation and purification of two benzoxazinoid glucosides from Acanthus ilicifolius L. by high-speed counter-current chromatography. Journal of Chromatography A2008, 1205, 177-181.11
Wang L, Zhao D, Liu Y*.Quality assessment of Veratrum nigrumL. by LC-ELSD fingerprints and LC quantitative analysis. Chromatographia2008, 68, 961-967. 1
Liu Y*, Murakami N, Wang L, Zhang S. Preparative high-performance liquid chromatography for the purification of natural acylated anthocyanins from red radish (Raphanus sativusL). Journal of Chromatographic Science2008, 46(8), 743-746.4
Liu Y*, Ji H, Dong J, Zhang S. Lee K, Matthew S.Antioxidant alkaloid from South China Sea marine sponge Iotrochotasp.Zeitschrift Fur Naturforschung 2008, 63c, 636-638.6
Wang L, Li W, Liu Y*. Hypotensive effect and toxicology of total alkaloids and veratramine from roots and rhizomes of Veratrum nigrumL. in spontaneously hypertensive rats. Pharmazie2008, 63(8), 606-610.3
Jiang S, Li X, Zhang L, Sun W, Dai S, Xie L, Liu Y, Lee K. Culturable actinobacteria isolated from marine sponge Iotrochotasp. Marine Biology2008, 153(5), 945-952.15
Jiang S, Sun W, Chen M, Dai S, Zhang L, Liu Y, Lee K, Li X. Diversity of culturable actinobacteria isolated from marine sponge Haliclonasp.Antonie Van Leeuwenhoek International Journal of General and Molecular Microbiology2007, 92(4), 405-416.41
Liu Y*, Ji H, Zhang S, Murakami N, Xu T. Structure-activity relationships of1'- acetoxychavicol acetate homologues as new nuclear export signal inhibitors.Pharmazie2007, 62(9), 659-662.Die Pharmazie-An International Journal of Pharmaceutical Sciences.1
Liu Y*, Zhang S, Jung J, Xu T. Variabilin, a chemotaxonomic marker for the familly Irciniidae. Zeitschrift Fur Naturforschung2007, 62c, 473-476.1
Jung J, Shinde P, Hong J, Liu Y, Sim C. Secondary metabolites from a marine sponge Discodermia calys. Biochemical Systematics and Ecology 2007, 35, 48-51.4
Liu Y*, Murakami N, AbreuP, Ji H, Zhang S. Antimalarial flavonol glycosides from Euphorbia hirta. Pharmaceutical Biology2007, 45(4), 278-281.12
Liu Y*, Jung J, Zhang S. An unsaturated ω-hydroxy methyl ester from a sponge Sarcotragusspecies. Chemistry of Natural Compounds2006, 42(4), 487-488.0
Liu Y, Abreu P.Long chain alkyl and alkenyl phenols from Ozoroa insignis. Journal of the Brazilian Chemical Society2006, 17(3), 527-536.5
Liu Y*, Jung J, Zhang S. Indole alkaloids from a sponge Sarcotragusspecies. Biochemical Systematics and Ecology2006, 34(5), 453-456.2
Liu Y, Shinde PB, Hong J, Lee C-O, Im KS, Jung JH. Trisoxazole macrolide from a marine spongeSarctragusspecies. Natural Product Sciences2005, 11(1), 50-53.
Zhao Q, Liu Y, Hong J, Lee C-O, Park JH, Lee DS, Jung JH. A new cyclitol derivatives from a spongeStellettaspecies. Natural Product Sciences2003, 9(1), 18-21.
发表论文(1)Three new highly oxygenated sterols and one new dihydroisocoumarin from the marine sponge-derived fungus Cladosporium sp . SCSIO41007,Steroids,2018,通讯作者(2)Perylenequione derivatives with anticancer activities isolated from the marine sponge-derived fungus, Alternaria sp. SCSIO41014,Marine Drugs,2018,通讯作者(3)Structurally diverse polyketidesfrom the mangrove-derived fungus Diaporthe sp. SCSIO 41011 with their anti-influenza A virus activities,Frontiers in Chemistry,2018,通讯作者(4)Prenylated indole alkaloids and chromone derivatives from the fungus Penicillium sp. SCSIO041218,Tetrahedron,2018,通讯作者(5)Norisoprenoids from the brown alga Sargassum naozhouense Tseng et Lu.,Molecules,2018,通讯作者(6)Bioactive novel indole alkaloids and steroids from deep sea-derived fungus Aspergillus fumigatus SCSIO 41012,Molecules,2018,通讯作者(7)New chlorinated diphenyl ethers and xanthones from a deep-sea-derived fungus Penicillium chrysogenum SCSIO 41001,Fitoterapia,2018,通讯作者(8)Spiro-phthalides and isocoumarins isolated from the marine-sponge-derived fungus Setosphaeria sp. SCSIO41009,Journal of Natural Products,2018,通讯作者(9)Isochromophilones A-F, cytotoxic chloroazaphilones from the marine mangrove endophytic fungus Diaporthe sp SCSIO 41011,Journal of Natural Products,2018,通讯作者(10)Peptides from the soft coral-associated fungus Simplicillium sp. SCSIO41209,Phytochemistry,2018,通讯作者(11)Soliseptide A, A Cyclic Hexapeptide Possessing Piperazic Acid Groups from Streptomyces solisilvae HNM30702,Organic Letters,2018,通讯作者(12)Three new polyketides from the marine sponge-derived fungus Trichoderma sp. SCSIO41004,Natural Product Research,2017,通讯作者(13)Chaetochromones A-C, Three New Polyketides from Mangrove Plant Derived Endophytic Fungus Phomopsis sp. SCSIO 41006,Chemistry & Biodiversity,2017,通讯作者(14)Isobenzofuranones and Isochromenones from the Deep-Sea Derived Fungus Leptosphaeria sp. SCSIO 41005,Marine Drugs,2017,通讯作者(15)Antituberculosis compounds from a deep-sea-derived fungus Aspergillus sp. SCSIO Ind09F01,Natural Product Research,2017,通讯作者(16)Pestalachloride E, a new chlorinated benzophenone derivative from mangrove endophytic fungus Pestalotiopsis versicolor,Chinese Journal of Antibiotics,2017,通讯作者(17)Vaccinols J-S, ten new salicyloid derivatives from the marine mangrove-derived endophytic fungus Pestalotiopsis vaccinii,Fitoterapia,2017,通讯作者(18)One Strain-Many Compounds Method for Production of Polyketide Metabolites Using the Sponge-Derived Fungus Arthrinium arundinis ZSDS1-F3,Chemistry of Natural Compounds,2017,通讯作者(19)中国南海深海真菌Exophiala sp. SCSIO 05791次级代谢产物研究,天然产物研究与开发,2017,通讯作者(20)中国南海深海真菌Penicillium brocae SCSIO 05793的次级代谢产物研究,中国海洋药物,2017,通讯作者(21)Chrysamides A-C, Three Dimeric Nitrophenyl trans-Epoxyamides Produced by the Deep-Sea-Derived Fungus Penicillium chrysogenum SCSIO41001,Organic Letters,2016,通讯作者(22)Antifungal New Oxepine-Containing Alkaloids and Xanthones from the Deep-Sea-Derived Fungus Aspergillus versicolor SCSIO 05879,J. Agric. Food Chem,2016,通讯作者(23)Design, synthesis and cytotoxic activities of novel 2,5-diketopiperazine derivatives,European Journal of Medicinal Chemistry,2016,通讯作者(24)Asteltoxins with antiviral activities from the marine sponge-derived fungus Aspergillus sp. SCSIO XWS02F40,Molecules,2016,通讯作者(25)Two new anthraquinones with antiviral activities from the barks of Morinda citrifolia (Noni),Phytochemistry Letters,2016,通讯作者(26)Antiviral merosesquiterpenoids produced by an antarctic fungus Aspergillus ochraceopetaliformis SCSIO 05702,Journal of Natural Products,2016,通讯作者(27)Site selective synthesis of cytotoxic 1,3,6-trisubstituted 3,6-diunsaturated (3Z,6Z)-2,5-diketopiperazines via a one-pot multicomponent method.,Tetrahedron,2016,通讯作者(28)Aspernigrins with anti-HIV-1 activities from the marine-derived fungus Aspergillus niger SCSIO Jcsw6F30,Bioorganic & Medicinal Chemistry Letters,2016,通讯作者(29)Arthpyrones A–C, Pyridone Alkaloids from a Sponge-Derived Fungus Arthrinium arundinis ZSDS1-F3,Organic Letters,2015,通讯作者(30)New Meroterpenoids from the Endophytic Fungus Aspergillus flavipes AIL8 Derived from the Mangrove Plant Acanthus ilicifolius,Marine Drugs,2015,通讯作者(31)New glucosidated pyrazinoquinazoline indole alkaloids from fungus Aspergillus fumigatus derived of a jellyfish,Tetrahedron,2015,通讯作者(32)New Prenylxanthones from the Deep-Sea Derived Fungus Emericella sp. SCSIO 05240,Marine Drugs,2014,通讯作者(33) ,New prenylated indole alkaloids from fungus Penicillium sp. derived of mangrove soil sample.,Tetrahedron,2014,通讯作者(34)Design and synthesis of novel soluble 2,5-diketopiperazine derivatives as potential anticancer agents,European Journal of Medicinal Chemistry,2014,通讯作者(35)New phenyl derivatives from endophytic fungus Aspergillus flavipes AIL8 derived of mangrove plant Acanthus ilicifolius,Fitoterapia,2014,通讯作者(36)Antifouling briarane type diterpenoids from South China Sea gorgonians Dichotella gemmacea.,Tetrahedron,2013,通讯作者(37)Peng Y, Xie E, Zheng K, Fredimoses M, Yang Y, Zhou X, Wang Y, Yang B, Lin X, Liu J, Liu Y. Nutritional and Chemical Composition and Antiviral Activity of Cultivated Seaweed Sargassum naozhouense Tseng et Lu.,Marine Drugs ,2013,通讯作者(38) Isolation, characterization, and bioactivity evaluation of, Marine Drugs,2013,通讯作者(39)Sesterterpenoids,Natural product Reports,2013,通讯作者(40)Marine Natural Products with Anti-HIV Activities in the Last Decade ,CURRENT MEDICINAL CHEMISTRY ,2013,通讯作者(41)Two new alkaloids from marine sponge Callyspongia sp. ,Natural product research ,2013,通讯作者(42)Antitumor steroids from the starfish Archaster typicus,Food Chemistry ,2011,通讯作者(43)Dichotellides A-E, five new iodine-containing briarane type diterpenoids from Dichotella gemmacea.,Tetrahedron,2011,通讯作者(44)The anti-hyperplasia of mammary gland effect of Thladiantha dubia root ethanol extract in rats reduced by estrogen and progestogen., Journal of Ethnopharmacology,2011,通讯作者(45)Chemical constituents and bioactivities of starfish. ,Chemistry Biodiversity,2011,通讯作者(46)New cyclitol derivative from a sponge Sarcotragus species. ,Natural Products Research,2011,通讯作者(47)Chemical and Biological Studies of Soft Corals Nephtheidae Family. ,Chemistry Biodiversity,2011,通讯作者(48)Identification of epidioxysterol from South China Sea urchin Tripneustes gratilla Linnaeus and its cytotoxic activity. ,Journal of Food Biochemistry,2011,通讯作者(49)Nucleosides from the marine sponge Callyspongia sp. ,Chemistry of Natural Compounds,2011,通讯作者(50)Two novel alkaloids from the South China Sea marine sponge Dysidea sp. ,Journal of Antibiotics,2010,通讯作者(51)Bryostatins from South China Sea bryozoan Bugula neritina L.,Biochemical Systematics and Ecology,2010,通讯作者(52)Chemical and biological aspects of marine sponge of the genus Xestospongia. ,Chemistry Biodiversity,2010,通讯作者(53)A novel cyclopentene derivative and a polyhydroxylated steroid from a South China Sea gorgonian Menella sp. ,Cheimcal Pharmaceutical Bulletin,2010,通讯作者(54)Polyhydroxysteroids and saponins from the China Sea starfish Asterina sp. and their biological activities. ,Chemical Pharmaceutical Bulletin,2010,通讯作者(55)A new N-acyl taurine from the sea urchin Glyptocidaris crenularis. ,Bioscience, Biotechnology and Biochemistry ,2010,通讯作者(56)Chemical constituents from the sea urchin Glyptocidaris crenularis. ,Biochemical Systematics and Ecology,2010,通讯作者(57)Hypolipidemic effect of fucoidan from Laminaria japonica in hyperlipidemic rats. ,Pharmaceutical Biology,2010,通讯作者(58)A new lignan from Saururus chinensis. ,Chemistry of Natural Compounds,2010,通讯作者(59)Lignans from Saururus chinensis. ,Chemistry of Natural Compounds,2010,通讯作者(60)A new 1,4-diazepine from South China Sea marine sponge Callyspongia species. ,Molecules,2010,通讯作者(61)A new triterpene hexaglycoside from the bark of Kalopanax septemlobus (Thunb.) Koidz. ,Molecules,2009,通讯作者(62)he hepatoprotective and antifibrotic effects of Saururus chinensis against carbon tetrachloride induced hepatic fibrosis in rats. ,Journal of Ethnopharmacology ,2009,通讯作者(63)Proline-containing dipeptides from the marine sponge a Callyspongia species. ,Helvetica Chimica Acta,2009,通讯作者(64)Nucleosides from marine sponges including known ones from Haliclona sp. ,Zeitschrift Fur Naturforschung,2009,通讯作者(65)2-Palmitamidoethanesulfonic acid, new aminoethylsulfonic acid derivative from marine sponge Haliclona sp. ,Chemistry of Natural Compounds,2009,通讯作者(66)GC-MS analysis of the supercritical CO2 fluid extraction of Ephedra sinica roots and its antisudorific activity. ,Chemistry of Natural Compounds,2009,通讯作者
发表著作(1)活性海绵呋喃二倍半萜,Bioactive furanosesterterpenoids from marine sponge,Springer-Verlag Berlin Heidelberg Press,2007-02,第1作者(2)传统利尿药-泽泻,Alisma orientale (Sam.) Juzep., a Common Traditional Chinese Medicine Plant as a Diuretic Agent, Stadium Pree LLC, U.S.A.,2009-01,第3作者(3)藻类活性产物,Bioactive metabolites from seaweeds,Wiley-Blackwell publisher,2011-10,第5作者(4)海洋药妆品的化学性质,Chemical Properties of Marine Cosmeoceuticals,Taylor Francis CRC Press,2011-11,第1作者(5)具有抗肿瘤活性的Briarane型二萜,Cytotoxic Briarane-type Dierpenoids,CRC press,2013-05,第1作者(6)海草化学成分,Chemical composition of seaweeds,Elsevier publishers,2015-01,第2作者(7)Advances in Natural Products Discovery,Nova Science Publishers Inc.,2017-01,第3作者
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中国科学院大学研究生导师教师师资介绍简介-刘永宏
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相关话题/中国科学院大学 师资
中国科学院大学研究生导师教师师资介绍简介-刘勇勤
基本信息刘勇勤女博导中国科学院青藏高原研究所电子邮件:yqliu@itpcas.ac.cn通信地址:北京市朝阳区林萃路16号院3号楼邮政编码:100101研究领域青藏高原冰雪与湖泊微生物与气候环境关系招生信息招生专业070501-自然地理学071300-生态学招生方向青藏高原冰川湖泊微生物与气候环境之间的关系冰冻圈微生物多样性与气候环境关系教育背景2004-09--2007-06中国科学院青藏高原 ...中国科学院大学师资导师 本站小编 Free考研考试 2020-04-27中国科学院大学研究生导师教师师资介绍简介-刘勇
基本信息刘勇男博导中国科学院自动化研究所电子邮件:yliu@nlpr.ia.ac.cn通信地址:北京市海淀区中关村东路95号智能化大厦501邮政编码:100190部门/实验室:模式识别国家重点实验室研究领域医学大数据计算模式识别与智能系统医学影像智能系统招生信息招生专业081104-模式识别与智能系统081203-计算机应用技术招生方向医学图像处理人工智能与医学大数据脑网络及其临床应用教育背景20 ...中国科学院大学师资导师 本站小编 Free考研考试 2020-04-27中国科学院大学研究生导师教师师资介绍简介-刘玉贵
基本信息刘玉贵男硕导计算机科学与技术学院电子邮件:liuyg@ucas.ac.cn通信地址:石景山区玉泉路19号甲邮政编码:100049部门/实验室:计算机与控制学院研究领域招生信息招生专业081203-计算机应用技术招生方向多媒体技术教育背景1993-09--1996-06中国科学技术大学研究生院(北京)工学硕士1979-09--1984-07北京大学数学系理学学士学历学位工作经历工作简历199 ...中国科学院大学师资导师 本站小编 Free考研考试 2020-04-27中国科学院大学研究生导师教师师资介绍简介-刘源
基本信息刘源男硕导中国科学院数学与系统科学研究院电子邮件:liuyuan@amss.ac.cn通信地址:中关村东路55号,思源楼526室邮政编码:部门/实验室:应用数学研究所研究领域招生信息招生专业070103-概率论与数理统计招生方向泛函不等式,马氏过程遍历性教育背景1998-09--2006-01清华大学数学系理科博士(直博)1994-09--1998-07清华大学数学系理科学士学历学位工作经 ...中国科学院大学师资导师 本站小编 Free考研考试 2020-04-27中国科学院大学研究生导师教师师资介绍简介-刘昱
基本信息刘昱男博导中国科学院微电子研究所电子邮件:liuyu5@ime.ac.cn通信地址:朝阳区北土城西路3号中国科学院微电子研究所十一室邮政编码:100029部门/实验室:健康电子中心研究领域模拟射频集成电路,硅基毫米波集成电路,低功耗无线收发机,低功耗生物传感芯片招生信息微电子与固体电子学,电子与通信工程教育背景2000-07--2002-09美国加利福尼亚大学圣芭芭拉分校工学博士学位199 ...中国科学院大学师资导师 本站小编 Free考研考试 2020-04-27中国科学院大学研究生导师教师师资介绍简介-刘育梁
基本信息刘育梁男博士生导师半导体研究所电子邮件:ylliu@semi.ac.cn通信地址:北京912信箱邮政编码:100083个人主页:http://lab.semi.ac.cn/yanjiusheng/contents/1323/115917.html部门/实验室:光电系统实验室研究领域光电成像与机器视觉;传感器与人工智能系统;光传感与光通信;光子集成招生信息招生专业1、微电子学与固体电子学;2 ...中国科学院大学师资导师 本站小编 Free考研考试 2020-04-27中国科学院大学研究生导师教师师资介绍简介-刘曰武
基本信息刘曰武男博导中国科学院力学研究所电子邮件:lywu@imech.ac.cn通信地址:北京市海淀区北四环西路15号邮政编码:100190研究领域招生信息招生专业080103-流体力学招生方向流体力学,渗流力学,油气藏工程教育背景1997-09--1999-11中国科学院力学研究所博士后1994-03--1997-07中国科学院渗流流体力学研究所博士学位1988-08--1991-09中国科学 ...中国科学院大学师资导师 本站小编 Free考研考试 2020-04-27中国科学院大学研究生导师教师师资介绍简介-刘媛媛
基本信息刘媛媛女硕导中国科学院半导体研究所电子邮件:liuyy@semi.ac.cn通信地址:半导体研究所家属区11号楼261邮政编码:100083部门/实验室:集成技术中心研究领域招生信息招生专业080903-微电子学与固体电子学085208-电子与通信工程招生方向硅基集成高亮度半导体激光光源关键技术教育背景2000-09--2003-07中国科学院半导体研究所博士学历学位工作经历工作简历201 ...中国科学院大学师资导师 本站小编 Free考研考试 2020-04-27中国科学院大学研究生导师教师师资介绍简介-刘云
基本信息刘云副院长/教授,博士生导师电子邮件:liuyun@ucas.ac.cn通信地址:北京市石景山区玉泉路19号(甲)邮政编码:100049部门/实验室:公共政策与管理学院研究领域科技评价、创新管理、知识产权管理、科技政策、数据挖掘学术简介长期从事科技评价、科技政策、创新管理、知识产权管理、数据挖掘等领域的研究工作。担任中国科学学与科技政策研究会常务理事、中国软科学学会常务理事、中国技术经济学 ...中国科学院大学师资导师 本站小编 Free考研考试 2020-04-27中国科学院大学研究生导师教师师资介绍简介-刘月仙
基本信息刘月仙女硕导资源与环境学院电子邮件:liuyuexian@ucas.ac.cn通信地址:北京市玉泉路19号(甲)邮政编码:100049部门/实验室:资源与环境学院研究领域农产品质量安全、低碳农业环境评估、农业面源污染治理教育背景2007-02--2010-01丹麦哥本哈根大学博士1998-09--2001-07中国农业大学硕士1994-09--1998-07中国农业大学学士工作经历2001 ...中国科学院大学师资导师 本站小编 Free考研考试 2020-04-27