基本信息
闫桂英女博导中国科学院数学与系统科学研究院
电子邮件： yangy@amt.ac.cn
通信地址： 北京市中关村东路55号
邮政编码： 100190

研究领域

招生信息
招生专业070105-运筹学与控制论

招生方向图论及其应用
生物信息学


教育背景1985-09--1995-06山东大学本科/硕士/博士

学历
学位

工作经历
工作简历2005-04~现在,中国科学院数学与系统科学研究院,研究员
1999-01~2005-03,中国科学院数学与系统科学研究院,副研究员
1997-03~1998-12,中国科学院应用数学所,助理研究员
1995-07~1997-02,中国科学院应用数学所,博士后

社会兼职2016-08-16-2020-07-31,中国工业与应用数学学会, 秘书长
2012-11-01-2016-10-31,中国运筹学会, 常务理事
2012-03-28-今,运筹与管理, 编委
2009-09-28-2015-12-30,Discrete Mathematics, Algorithms and Applications》, Editorial Board Member
2009-09-01-今,《应用数学学报》, 编委


教授课程组合数学


专利与奖励
奖励信息（1） 全国优秀科技工作者, 一等奖, 国家级, 2016
（2） 国务院政府特殊津贴, 一等奖, 国家级, 2013

专利成果（ 1 ） 一种药物增效组合预测方法及实验验证, 发明, 2014, 第 1 作者, 专利号: ZL 8.0


出版信息
发表论文（1）A novel approach based on KATZ measure to predict associations of human microbiota with non-infectious diseases,Bioinformatics, 33(5), 2017, 733–739,2017,第4作者
（2）HAMDA: Hybrid Approach for MiRNA-Disease Association prediction,Journal of Biomedical Informatics,2017,第4作者
（3）NRDTD: a database for clinically or experimentally supported non-coding RNAs and drug targets associations,Database, 2017, 1–6,2017,第4作者
（4）PBHMDA: Path-Based Human Microbe-Disease Association Prediction,frontiers in Microbiology,2017,第5作者
（5）PBMDA: A novel and effective path-based computational model for miRNA-disease association prediction,PLOS Computational Biology,2017,第4作者
（6）Prediction of microbe–disease association from the integration of neighbor and graph with collaborative recommendation model,Journal of Translational Medicine,2017,第6作者
（7）RKNNMDA: Ranking-based KNN for MiRNA-Disease Association prediction,RNA Biology,2017,第3作者
（8）A novel computational model based on superdisease and miRNA for potential miRNA–disease association prediction,Molecular BioSystems,2017,第5作者
（9）MCMDA: Matrix completion for MiRNA-disease association prediction,Oncotarget,2017,第4作者
（10）LRLSHMDA: Laplacian Regularized Least Squares for Human Microbe– Disease Association prediction,scientific reports,2017,第6作者
（11）NLLSS: Predicting Synergistic Drug Combinations Based on Semi-supervised Learning,PLoS Computational Biology,2016,通讯作者
（12）IRWRLDA: Improved random walk with restart for lncRNA-disease association prediction,Oncotarget,2016,第3作者
（13）Prediction of disease-related interactions between microRNAs and environmental factors based on a semi-supervised classifier,PLoS ONE,2012,通讯作者
（14）Minimum degree, edge-connectivity and radius,Journal of Combinatorial Optimization,2012,第4作者
（15）A Note on Semi-coloring of Graphs,Graphs and Combinatorics,2012,通讯作者
（16）Planar graphs with maximum degree 8 and without intersecting chordal 4-cycles are 9-totally colorable,Science in China,2012,通讯作者
（17）RWRMDA: predicting novel human microRNA-disease associations,Molecular BioSystems,2012,通讯作者
（18）Drug–target interaction prediction by random walk on the heterogeneous network,Molecular BioSystems,2012,通讯作者
（19）A novel disease genes prioritization method using module partition and rank fusion,OMICS: A Journal of Integrative Biology,2010,通讯作者
（20）Simple Probabilistic Algorithm for Detecting Community Structure in Social Networks,Phys. Rev. E,2009,通讯作者
（21）On potentially Kr+1 - U-graphical Sequences,UTILITAS MATHEMATICA,2009,通讯作者
（22）Graphs Isomorphic to Their Maximum Matching Graphs,Acta Mathematica Sinica,2009,通讯作者
（23）Induced Subgraph in Random Regular Graph,J. of Sys. Sci. and Complexity,2008,第2作者
（24）Factor-Critical Graphs with Given Number of Maximum Matchings,Graphs and Combinatorics,2008,通讯作者
（25）Linear Time Construction of 5-Phylogenetic Roots for Tree Chordal Graphs,Journal of Combinatorial Optimization,2008,通讯作者
（26）A Full-scale Solution to the Rectilinear Obstacle-Avoiding Steiner Problem,Elsevier INTEGRATION, the VLSI Journal,2008,通讯作者
（27）Detecting Community Structure by Network Vectorization,In Proceedings of The 14th International Computing and Combinatorics Conference, LNCS 5092,2008,第2作者
（28）l-OAT: l-Geometry Obstacle-Avoiding Tree Construction with O(nlogn) Complexity,IEEE Trans. on COMPUTER-AIDED DESIGN of Integrated Circuits and Systems,2007,通讯作者
（29）An O(nlogn) Algorithm for Obstacle-Avoiding Routing Tree Construction in the λ-Geometry Plane,In: Proceedings of ACM International Symposium on Physical Design (ISPD),2006,通讯作者
（30）DraXRouter: Global Routing in X-Architecture with Dynamic Resource Assignment,In: Proceedings of IEEE/ACM Asia and South Pacific Design Automation Conference (ASP-DAC),2006,通讯作者
（31）Strictly chordal graphs are leaf powers,Journal of Discrete Algorithms,2006,通讯作者
（32）ACO-Steiner: Ant Colony Optimization Based Rectilinear Steiner Minimal Tree Algorithm,Journal of Computer Science Technology,2006,通讯作者
（33）Via-Aware Global Routing for Good VLSI Manufacturability and High Yield,Proc.of IEEE 16th International Conference on Application-specific Systems, Architectures and Processors,2005,通讯作者
（34）A Routing Paradigm with Novel Resources Estimation and Routability Models for X-Architecture Based Physical Design,International Workshop on Embedded Computer Systems: Architectures, Modeling, and Simulation, Lecture Notes in Computer Science,2005,通讯作者
（35）The Polygonal Contraction heuristic for Rectilinear Steiner Tree Construction,Proceedings of IEEE/ACM ASP-DAC,2005,通讯作者
（36）An-OARSMan: Obstacle-Avoiding Routing Tree Construction with Good Length Performance,Proceedings of IEEE/ACM ASP-DAC,2005,通讯作者
（37）An Efficient Low-Degree RMST Algorithm for VLSI/ULSI Physical Design, Integrated Circuits and System Design, Springer Lecture Notes in Computer Science (LNCS),2004,通讯作者
（38）Path Decomposition of 3-regular Graphs, Journal of System Sciences and Mathematics Science,2004,第1作者
（39）Isolated Toughness and Fractional k-Covered Graphs,Acta Mathematicae Sinica,2004,第2作者
（40）The Structural Properties of Hexagonal Steiner Minimum Trees for Terminals on the Boundary of an Equilateral Triangle,Journal of Information and Computational Science ,2004,通讯作者
（41）An Efficient Rectilinear Steiner Minimum Tree Algorithm Based on Ant Colony Optimization,Proceedings of IEEE ICCCAS,2004,通讯作者
（42）Some result on the Graphic Isolated Toughness and Fractional Factor,Acta Mathematicae Sinica,2004,第2作者
（43）Isolated Toughness and Fractional k-Deleted Graphs,OR Transactions,2003,第2作者
（44）On Fractional (g,f)-deleted Graphs,Mathematica Applicata,2003,第2作者
（45）On Fractional (g,f)-Covered Graphs,OR Transactions,2002,通讯作者
（46）The Cycle Structure of Hypergraphs,Chinese Science Bulletin,2001,第1作者
（47）Linear Vertex Arboricity, Independence Number and Clique Cover Number,Ars Combinatoria,2001,通讯作者
（48）An Application of Hypergraph on the Generalized Gossip Problem,the proceedings of the sixth National Conference of Operations Research Society of China,2001,通讯作者
（49）Decomposition Graphs into (g,f)-Factors,Graphs and Combinatorics,2000,第1作者
（50）A New Result on Alspach’s Problem,Graphs and Combinatorics,1999,第1作者
（51）On the Optimal Four-Way Switch Box Routing Structures of FPGA Gready Routing Architectures, Integration,The VLSI Journal,1998,通讯作者
（52）Orthogonal (g,f)-Factorization in Bipartite Graph,Hokkaido Math. Journal,1998,第1作者
（53）The Existence of Subgraph with Orthogonal (g,f)- Factorization,Science in China (English Version),1998,第1作者
（54）The Steiner Tree problem with orientation Metrics,J.of Computer System Sciences,1997,第1作者
（55）(g,f)-Factorizations of Graphs Orthogonal to [1, 2]-Subgraph,Acta Mathematicae Applicatae Sinica,1997,第1作者
（56）Orthogonal [k-1,k+1]-factorizations in graphs,J. Statistical Planning and Inference,1996,第2作者
（57）New Results on (g,f)-Factorizations of Graphs,Mathematica Applicata,1996,第1作者
（58）Some New Result on (g,f)-Factorizations of Graphs,Journal of Combinatorial Mathematics and Combinatorial Computing,1995,第1作者
（59）(g,f)-Factorizations of Graphs,Journal of System Sciences and Mathematics Science,1995,第1作者
（60）(g,f)-factors with given properties,Journal of Shandong University,1995,第1作者
（61）The Existence of k-fator and the Condition of Neighbourhood Union,Pure Applied Mathematics,1994,第1作者
（62）Some Theorems on (g,f)-Factorizations of Graphs, Combinatorics,Graph Theory, Algorithms and Applications,1994,第1作者
（63）on (g,f)-Factorizations of Graphs,Journal of Shandong University,1993,第1作者

发表著作

科研活动
科研项目（ 1 ） 随机复杂数据与随机复杂结构理论方法及其应用, 参与,国家级,2009-01--2013-12
（ 2 ） 优化方法及其在信息技术中的应用, 主持,部委级,2009-01--2012-12
（ 3 ） 图理论和算法研究及其在生物信息学中的应用, 主持,国家级,2017-01--2020-12
（ 4 ） 复杂疾病相关的非编码RNA识别模型及算法研究, 主持,国家级,2013-01--2017-12
（ 5 ） 协同药物研发中的关键数学问题, 主持,国家级,2013-01--2013-12

参与会议

合作情况
项目协作单位

指导学生已指导学生
程郁琨硕士研究生070105-运筹学与控制论
肖岚博士研究生070105-运筹学与控制论
任伟博士研究生070105-运筹学与控制论
吴玉文博士研究生070105-运筹学与控制论
廖小平博士研究生070105-运筹学与控制论
王艺桥博士研究生070105-运筹学与控制论
陈兴博士研究生070105-运筹学与控制论
刘明熹博士研究生070105-运筹学与控制论
徐鑫博士研究生070105-运筹学与控制论
张瑶博士研究生070105-运筹学与控制论
唐与聪博士研究生070105-运筹学与控制论
曹鲁博士研究生070105-运筹学与控制论
现指导学生
张成芝博士研究生070105-运筹学与控制论
周乐为博士研究生070105-运筹学与控制论
王齐 硕士研究生070105-运筹学与控制论
马驰骋 博士研究生070105-运筹学与控制论
田雷霞博士研究生070105-运筹学与控制论