基本信息
陈俊 男 硕导 高能物理研究所
电子邮件:chenjun@ihep.ac.cn
通信地址:北京市石景山区玉泉路19号(乙)中国科学院高能物理研究所
邮政编码:100049
研究领域1 Design, Construction and Characterization of Stimuli (redox potential, pH, light…) Responsive Polymeric Gene/Drug Delivery Systems;
2 Development of Nanomaterials for tumor diagnostic and therapeutic applications;
3 Development of Novel Biomaterials for Tissue Engineering.
招生信息硕士生每年一名
招生专业 高分子化学与物理
招生方向 生物医用高分子,纳米材料,生物材料
抗肿瘤治疗,基因治疗
教育背景 2001-09--2007-06 武汉大学 理学博士
1997-09--2001-06 武汉大学 理学学士
学历
学位
工作经历
工作简历 2013-02--今 中国科学院高能物理研究所 副研究员
2012-02--2013-01 University of Manitoba 助理研究员
2009-02--2012-01 University of Manitoba 博士后
2007-09--2008-11 Wayne State University 博士后
社会兼职
教授课程
专利与奖励
奖励信息
专利成果 (1) Multifunctional nanoparticle for doxorubicin enhanced intracellular delivery,发明,2012,第1作者,专利号:61/586,833
出版信息
发表论文 (1) Reducible polyamidoamine-magnetic iron oxide self-assembled nanoparticles for doxorubicin delivery,Biomaterials,2014,第1作者
(2) A PNIPAAm-based thermosensitive hydrogel containing SWCNTs for stem cell transplantation in myocardial repair,Biomaterials,2014,第4作者
(3)Engineering the heart: Evaluation of conductive nanomaterials for improving implant integration and cardiac function,Scientific Reports,2014,第1作者
(4)Free-Standing Cell Sheet Assembled with Ultrathin Extracellular Matrix as an Innovative Approach for Biomimetic Tissues,Advanced Functional Materials,2014,第1作者
(5) Opposing influence of intracellular and membrane thiols on the toxicity of reducible polycations,Biomaterials,2013,第4作者
(6) Photo-cross-linked and pH-Sensitive Biodegradable Micelles for Doxorubicin Delivery,ACS Appl. Mater. Interfaces,2013,第1作者
(7) Effect of cell membrane thiols and reduction-triggered disassembly on transfection activity of bioreducible polyplexes,European Journal of Pharmaceutical Sciences,2012,第3作者
(8) Reducible self-assembled micelles for enhanced intracellular delivery of doxorubicin,Journal of Materials Chemistry,2012,第1作者
(9) pH and Reduction Dual-Sensitive Copolymeric Micelles for Intracellular Doxorubicin Delivery,Biomacromolecules,2012,第1作者
(10) Multifunctional Nanofibrous Scaffolds Based on Poly(L-lactic acid) and Poly(L-lactic acid)-Poly(ethylene glycol) for Tissue Engineering,International Journal of Nanomedicine,2011,第1作者
(11) Degradable micelles based on hydrolytically degradable amphiphilic graft copolymers for doxorubicin delivery,Polymer,2011,第1作者
(12) Novel Poly(amidoamine)s with Pendant Primary Amines as Highly Efficient Gene Delivery Vectors,Macromolecular Bioscience,2010,第2作者
(13) Bioreducible hyperbranched poly(amido amine)s for gene delivery,Biomacromolecules,2009,第1作者
(14) Poly(beta-aminoester)s with pendant primary amines for efficient gene delivery,Bioconjugate Chemistry,2009,第2作者
(15) Effect of intracellular glutathione levels on the cytotoxicity of bioreducible polycations,Molecular Therapy,2009,第2作者
(16) Effect of Nucleic Acid Size on Physical Properties and Biological Activity of Redox-Responsive Polyplexes: Plasmid DNA vs. Antisense Oligonucleotides,Molecular Therapy,2009,第3作者
(17) Synthesis and degradation of poly(beta-aminoester) with pendant primary amine,Polymer,2007,第1作者
(18) Tunable film degradation and sustained release of plasmid DNA from cleavable polycation/plasmid DNA multilayers under reductive conditions,Small,2007,第1作者
(19) A cleavable-polycation template method for the fabrication of noncrosslinked, porous polyelectrolyte multilayered films,Advanced Materials,2007,第1作者
发表著作
科研活动
科研项目 (1) 基于胞内多种生物活性分子同时识别的荧光探针研究,参与,部委级,2014-01--2018-12
(2) 近红外光敏多功能纳米载体的构建及药物靶向传递和成像研究,主持,部委级,2014-01--2016-12
(3) 用于癌症诊断治疗的纳米载体的研究,主持,研究所(学校)级,2013-02--2016-01
(4) 肝癌早期诊断用新型纳米材料的设计和构筑,参与,部委级,2012-09--2015-08
参与会议 (1) PREPARATION OF BIOCOMPATIBLE CONDUCTIVE NANOMATERIALS FOR IMPROVING MYOCARDIAL REPAIR,2014年国际高分子化学学术研讨会,2014-06,Ying Bi, Xiaohan Xu, Yanping Qin, Hui Zhou, Yi Hu, Jun Chen,
(2) Controlled release of Doxorubicin from pH and reducing agents dual responsive PEG-Reducible Poly(beta-amino ester)s-PEG micelles,2010-05,Jun Chen, Shufei Zhou and Wen Zhong
(3) Effect of intracellular glutathione levels on the cytotoxicity of bioreducible polycations,2009-05,Chao Wu, Jun Chen, Jing Li, David Oupicky
(4) Synthesis and characterization of hyperbranched poly(amido amine)s for gene delivery,2008-07,Ye-Zi You, Jun Chen, Devika S Manickam, Qing-Hui Zhou, Lei Wan, Guangzhao Mao and David Oupicky
(5) 聚酯-胺阳离子/质粒DNA 多层膜的构建及其控制释放DNA,2005 全国高分子学术论文报告会,2005-10,陈俊,黄世文,林文海,卓仁禧
合作情况动物体内实验合作单位:
温州医科大学检验医学院 高基民 教授
哈尔滨医科大学第一附属医院 刘宏宇 院长
天津医科大学 张宁教授
南方医科大学欧阳均 教授
材料实验合作单位:
中国科学院大学材料科学与光电技术学院 黄辉 教授
美国德州农工大学化学系 方磊 助理教授
中国科学院宁波材料技术与工程研究所 黄又举 副研究员
项目协作单位
指导学生
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