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中国科学院大学研究生导师简介-葛高翔

中国科学院大学 免费考研网/2016-05-09

1、招生信息2、教育背景3、工作经历4、教授课程5、专利与奖励6、出版信息7、科研活动8、合作情况9、指导学生
基本信息
葛高翔 男 博导 中国科学院上海生命科学研究院
电子邮件: gxge@sibs.ac.cn
通信地址: 上海市岳阳路320号新生化大楼1415室
邮政编码: 200031
研究领域
招生信息

招生专业071010


招生方向细胞微环境对肿瘤发生及转移的调控

教育背景1996-09--2001-08 中国科学院生物化学研究所 博士
1992-08--1996-08 南京大学 理学学士学位


学历

学位
工作经历

工作简历2007-12~现在, 中科院上海生化细胞所, 研究员
2002-10~2007-11,美国威斯康星大学麦迪逊分校, Scientist/博士后
2001-12~2002-09,美国田纳西大学健康科学中心, 博士后
2001-09~2001-11,中科院上海生化细胞所, 助理研究员
1996-09~2001-08,中国科学院生物化学研究所, 博士
1992-08~1996-08,南京大学, 理学学士学位


社会兼职
教授课程
专利与奖励

奖励信息

专利成果
出版信息

发表论文(1) LKB1 in Lung Cancerigenesis: A Serine/Threonine Kinase as Tumor Suppressor., Protein and Cell., 2011, 第 5 作者
(2) α3(V) Collagen is critical for glucose homeostasis in mice due to effects in pancreatic islets and peripheral tissues., J Clin Invest., 2011, 第 1 作者
(3) The CC and DE loops in Ig domains 1 and 2 of MAdCAM-1 play different roles in MAdCAM-1 binding to low- and high-affinity integrin a4b7., J Biol Chem., 2011, 第 5 作者
(4) LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling., Proc Natl Acad Sci U S A., 2010, 第 5 作者
(5) Fibronectin binds and enhances the activity of bone morphogenetic protein 1., J Biol Chem., 2009, 第 4 作者
(6) Secreted Frizzled-related protein 2 is a procollagen C proteinase enhancer with a role in fibrosis associated with myocardial infarction. , Nat Cell Biol., 2009, 第 5 作者
(7) ADAMTSL2 mutations in geleophysic dysplasia demonstrate a role for ADAMTS-like proteins in TGF-beta bioavailability regulation., Nat Genet., 2008, 第 5 作者
(8) Two domains of the epidermal growth factor receptor are involved in cytoskeletal interactions., Biochem Biophys Res Commun. , 2008, 第 3 作者
(9) Bone Morphogenetic Protein 1 Processes Prolactin to a 17kDa Anti-Angiogenic Form., Proc Natl Acad Sci U S A., 2007, 第 1 作者
(10) Bone Morphogenetic Protein 1 Prodomain Specifically Binds, Localizes and Regulates Signaling of Bone Morphogenetic Proteins 2 and 4., J Biol Chem, 2007, 第 2 作者
(11) Inhibition of bone morphogenetic protein 1 by native and altered forms of ?2-macroglobulin., J Biol Chem, 2006, 第 1 作者
(12) ., BMP1 controls TGF?1 activation via cleavage of latent TGF?-binding protein, J Cell Biol., 2006, 第 1 作者
(13) bmp1 and mini fin are functionally redundant in regulating formation of the zebrafish dorsoventral axis., Mech Dev., 2006, 第 2 作者
(14) TIMP-3 inhibits the procollagen N-proteinase ADAMTS-2., Biochem J., 2006, 第 4 作者
(15) Developmental roles of the BMP1/TLD metalloproteinases., Birth Defects Res C Embryo Today, 2006, 第 1 作者
(16) Mammalian tolloid-like 1 binds procollagen C-proteinase enhancer protein 1 and differs from bone morphogenetic protein 1 in the functional roles of homologous protein domains., J Biol Chem., 2006, 第 1 作者
(17) GDF11 forms a bone morphogenetic protein 1-activated latent complex that can modulate nerve growth factor-induced differentiation of PC12 cells., Mol Cell Biol., 2005, 第 1 作者
(18) Bone morphogenetic protein-1/tolloid-related metalloproteinases process osteoglycin and enhance its ability to regulate collagen fibrillogenesis., J Biol Chem., 2004, 第 1 作者
(19) Activation mechanism of solubilized epidermal growth factor tyrosine kinase., Biochem Biophys Res Commun, 2002, 第 1 作者
(20) Effect of membrane fluidity on tyrosine kinase activity of reconstituted Epidermal Growth Factor Receptor., Biochem Biophys Res Commun., 2001, 第 1 作者


发表著作
科研活动

科研项目( 1 )细胞生长过程细胞骨架可塑性的调控机制, 参与, 国家级, 2010-01--2014-12
( 2 )Lysyl Oxidase在肿瘤转移中的作用机制研究, 主持, 国家级, 2010-01--2012-12
( 3 )癌症重大科学问题及防治新策略的研究, 参与, 国家级, 2009-12--2011-07
( 4 )百人计划, 主持, 国家级, 2010-01--2012-12


参与会议(1)Cancer- An Overhealing Wound: Lysyl Oxidase in Lung Fibrosis and Cancer 第一届肿瘤新生血管和肿瘤微环境国际研讨会 Gaoxiang Ge 2011-05-30
(2)LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular Gaoxiang Ge 2010-11-12
(3)Activation of TGF-? Family Growth Factors by BMP-1/Tolloid-like Metalloproteinases Gaoxiang Ge 2009-10-27
(4)Activation of TGF-β family growth factors by BMP-1/Tolloid-like metalloproteinases Gaoxiang Ge 2009-09-12
(5)GDF11 forms a bone morphogenetic protein 1-activated latent complex that can modulate nerve growth factor-induced differentiation of PC12 cells Gaoxiang Ge 2004-10-11
(6)Activation mechanism of solubilized epidermal growth factor tyrosine kinase. 1 2000-10-21

合作情况

项目协作单位
指导学生

相关话题/细胞 肿瘤 中国科学院 信息 奖励