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中国科学院大学研究生导师简介-赖仞

中国科学院大学 免费考研网/2016-05-09

1、招生信息2、教育背景3、工作经历4、教授课程5、专利与奖励6、出版信息7、科研活动8、合作情况9、指导学生
基本信息
赖仞 男 博导 中国科学院昆明动物研究所
电子邮件: rlai@mail.kiz.ac.cn
通信地址: 云南省昆明市教场东路32号
邮政编码: 650223
研究领域
招生信息

招生专业071010


招生方向天然药物功能蛋白质组学

教育背景

学历

学位
工作经历

工作简历

社会兼职
教授课程
专利与奖励

奖励信息(1)基于生物生存策略的有毒动 物中药功能成分定向挖掘技术体系,部委级,2013
(2)中国青年科技奖,院级,2011
(3)中国科学院科学院十大杰出青年,院级,2010
(4)谈家桢生命科学奖,院级,2010
(5)中国科学院王宽诚西部突出贡献奖,院级,2010
(6)吸血蜱与宿主相互作用的分子机制,部委级,2009
(7)两栖动物功能活性多肽的结构与功能,国家级,2008


专利成果( 1 )棕点湍蛙抗菌肽及其基因和在制药中的应用,2011,第 1 作者,专利号: ZL**7.0
( 2 )无指盘臭蛙丙精肽、基因和变异体,2011,第 1 作者,专利号: ZL **1.5
( 3 )大蹼铃蟾多肽在制备抗肿瘤和艾滋病药物中的应用,2011,第 2 作者,专利号: ZL **.4
( 4 )一种环状小肽BA,2011,第 1 作者,专利号: ZL **5.0
( 5 )胡蜂抗菌肽及其制备方法和应用,2011,第 1 作者,专利号: ZL **4.7
( 6 )中华硬蜱神经肽及其制备方法和应用,2011,第 1 作者,专利号: ZL **5.1
( 7 )棕点湍蛙活性肽及其基因和在制药中的应用,2011,第 1 作者,专利号: ZL **8.5
( 8 )棕点湍蛙胰岛素释放促进肽,2011,第 1 作者,专利号: ZL **2.X
( 9 )无指盘臭蛙胰岛素释放促进肽和在制药中的应用,2011,第 1 作者,专利号: ZL **0.X
( 10 )无指盘臭蛙抗菌肽,2011,第 1 作者,专利号: ZL **8.3
( 11 )无指盘臭蛙丝氨酸蛋白酶抑制剂及其应用,2011,第 1 作者,专利号: ZL **0.0

出版信息

发表论文(1) Peptidomics combined with cDNA library unravel the diversity of centipede venom. , J Proteomics, 2015, 第 5 作者
(2) The chemistry and biological activities of peptides from amphibian skin secretions. , Chem Rev. , 2015, 第 5 作者
(3) A potential wound healing-promoting peptide from frog skin., Int J Biochem Cell Biol, 2014, 第 5 作者
(4) A potential wound-healing-promoting peptide from salamander skin. , FASEB J., 2014, 第 5 作者
(5) Discovery of a selective Na(V)1.7 inhibitor from centipede venom with analgesic efficacy exceeding morphine in rodent pain models, PNAS, 2013, 第 5 作者
(6) Human β-defensin 2 is a novel opener of Ca2+-activated potassium channels and induces vasodilation and hypotension in monkeys. , Hypertension, 2013, 第 5 作者
(7) Multiple coagulation factor deficiency protein 2 contains the ability to support stem cell self-renewal. , FASEB J, 2013, 第 5 作者
(8) A mycobacteriophage-derived trehalose-6,6-dimycolate-binding peptide containing both antimycobacterial and anti-inflammatory abilities., FASEB J., 2013, 第 5 作者
(9) Structure and function of a potent lipopolysaccharide-binding antimicrobial and anti-inflammatory peptide. , J Med Chem., 2013, 第 5 作者
(10) Dermatophagoides farinae allergens diversity identification by proteomics. , Mol Cell Proteomics., 2013, 第 5 作者
(11) Chemical punch packed in venoms makes centipedes excellent predators., Mol Cell Proteomics., 2013, 第 5 作者
(12) Structure of a protein having inhibitory disintegrin and leukotriene scavenging functions contained in a single domain., J Biol Chem, 2012, 第 5 作者
(13) A novel small Odorranalectin-bearing cubosomes: preparation, brain delivery and pharmacodynamic study on amyloid-β?????-treated rats following intranasal administration., Eur J Pharm Biopharm, 2012, 第 5 作者
(14) Purification and characterization of two new allergens from the venom of Vespa magnifica., PLoS One, 2012, 第 5 作者
(15) Purification and characterization of two new allergens from the salivary glands of the horsefly, Tabanus yao., Allergy, 2011, 第 5 作者
(16) Odorranalectin-conjugated nanoparticles: preparation, brain delivery and pharmacodynamic study on Parkinson disease following intranasal administration., J Control Release. , 2011, 第 5 作者
(17) There are abundant antimicrobial peptides in brains of two kinds of Bombina toads., J Proteome Res. , 2011, 第 5 作者
(18) Proteomic analysis of skin defensive factors of tree frog Hyla simplex, J Proteome Res. 2011 , 2011, 第 5 作者
(19) Cathelicidin-BF, a snake cathelicidin-derived antimicrobial peptide, could be an excellent therapeutic agent for acne vulgaris, PLoS One, 2011, 第 5 作者
(20) A bi-functional anti-thrombosis protein containing both direct-acting fibrin(ogen)olytic and plasminogen-activating activities, PLoS One, 2011, 第 5 作者
(21) A novel family of RGD-containing disintegrins (Tablysin-15) from the salivary gland of the horsefly Tabanus yao targets αIIbβ3 or αVβ3 and inhibits platelet aggregation and angiogenesis., Thromb Haemost, 2011, 第 5 作者
(22) A novel allergen Tab y 1 with inhibitory activity of platelet aggregation from salivary glands of horseflies, Allergy, 2011, 第 5 作者
(23) Two immunoregulatory peptides with antioxidant activity from tick salivary glands , J Biol Chem., 2010, 第 5 作者
(24) Frog skins keep redox homeostasis by antioxidant peptides with rapid radical-scavenging ability. , Free Radic Biol Med., 2010, 第 5 作者
(25) Antioxidant peptidomics reveals novel skin antioxidant system., Mol Cell Proteomics, 2009, 第 5 作者
(26) Anti-thrombosis repertoire of blood-feeding horsefly salivary glands. , Mol Cell Proteomics, 2009, 第 5 作者
(27) The first gene-encoded amphibian neurotoxin. , J Biol Chem., 2009, 第 5 作者
(28) Toward an understanding of the molecular mechanism for successful blood feeding by coupling proteomics analysis with pharmacological testing of horsefly salivary glands., Mol Cell Proteomics., 2008, 第 5 作者
(29) Anti-infection peptidomics of amphibian skin. , Mol Cell Proteomics. , 2007, 第 5 作者
(30) Trypsin inhibitory loop is an excellent lead structure to design serine protease inhibitors and antimicrobial peptides., FASEB J, 2007, 第 5 作者


发表著作( 1 )Combined peptidomics and genomics approach to the isolation of amphibian antimicrobial peptides. , Combined peptidomics and genomics approach to the isolation of amphibian antimicrobial peptides. , Springer, 2011-07, 第 1 作者

科研活动

科研项目( 1 )吸血节肢动物成功吸血的分子机制, 主持, 国家级, 2010-01--2013-12
( 2 )牛虻作为传统抗血栓中药的物质基础, 主持, 国家级, 2011-07--2011-07
( 3 )两栖动物抗菌功能基因发掘及抗菌肽分子资源库的建立, 主持, 国家级, 2011-07--2011-07
( 4 )肿瘤氧化还原蛋白质组学, 参与, 国家级, 2013-01--2017-12
( 5 )蜈蚣毒素来源的KV1.3抑制剂对牛皮癣治疗的分子机制及药物化学研究, 主持, 国家级, 2014-01--2017-12
( 6 )两栖动物皮肤修复的分子机制研究, 主持, 国家级, 2014-01--2017-12


参与会议
合作情况

项目协作单位
指导学生

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