1、招生信息2、教育背景3、工作经历4、教授课程5、专利与奖励6、出版信息7、科研活动8、合作情况9、指导学生
基本信息
马轶凡 女 硕导 中国科学院深圳先进技术研究院
电子邮件: yf.ma@siat.ac.cn
通信地址: 深圳市南山区西丽深圳大学城学苑大道1068号
邮政编码: 518055
研究领域
招生信息
招生专业0703J1
招生方向纳米材料介导的免疫治疗
教育背景2000-08--2005-12 美国宾夕法尼亚州立大学生命科学院 博士1994-09--1997-06 南京医科大学儿科系 硕士1989-09--1994-07 南京医科大学儿科系 学士
学历
学位
工作经历
工作简历2012-09~现在, 中国科学院深圳先进技术研究院, 研究员2008-09~2012-08,中国科学院深圳先进技术研究院, 副研究员2006-04~2008-08,美国Vaxdesign公司, 免疫科学家2000-08~2005-12,美国宾夕法尼亚州立大学生命科学院, 博士1997-09~1999-01,江苏省妇幼卫生保健中心, 儿科医师1994-09~1997-06,南京医科大学儿科系, 硕士1989-09~1994-07,南京医科大学儿科系, 学士
社会兼职
教授课程
专利与奖励
奖励信息
专利成果( 1 )纳米疫苗及其制备方法,2009,第 1 作者,专利号: **0( 2 )聚合物纳米载体制剂及制备方法,2012,第 1 作者,专利号: **1.7( 3 )阳离子脂质体及其制备方法,2011,第 1 作者,专利号: **6.4
出版信息
发表论文(1) Nanovaccine loaded with poly I:C and STAT3 siRNA robustly elicits anti-tumor immune responses through modulating tumor-associated dendritic cells in vivo., Biomaterials, 2015, 第 5 作者(2) Noninvasive Visualization of Respiratory Viral Infection Using Bioorthogonal Conjugated Near-Infrared-Emitting Quantum Dots., ACS Nano, 2014, 第 5 作者(3) Autophagy mediates avian influenza H5N1 pseudotyped particle-induced lung inflammation through NF-κB and p38 MAPK signaling pathways, Am J Physiol Lung Cell Mol Physiol. , 2014, 第 5 作者(4) Lymphatic-targeted cationic liposomes: a robust vaccine adjuvant for promoting long-term immunological memory., Vaccine, 2014, 第 5 作者(5) Smart human serum albumin-indocyanine green nanoparticles generated by programmed assembly for dual-modal imaging-guided cancer synergistic phototherapy., ACS Nano, 2014, 第 5 作者(6) Single-step assembly of DOX/ICG loaded lipid--polymer nanoparticles for highly effective chemo-photothermal combination therapy., ACS Nano, 2013, 第 1 作者(7) Bioreducible alginate-poly(ethylenimine) nanogels as an antigen-delivery system robustly enhance vaccine-elicited humoral and cellular immune responses., Journal of Controlled Release, 2013, 第 5 作者(8) Functionalized quantum dots induce proinflammatory responses in vitro: the role of terminal functional group-associated endocytic pathways., Nanoscale, 2013, 第 5 作者(9) Cationic polypeptide micelle-based antigen delivery system: A simple and robust adjuvant to improve vaccine efficacy, Journal of Controlled Release, 2013, 第 5 作者(10) Dextran based sensitive theranostic nanoparticles for near-infrared imaging and photothermal therapy in vitro., Chem Commun (Camb), 2013, 第 5 作者(11) PEGylated cationic liposomes robustly augment vaccine-induced immune responses: Role of lymphatic trafficking and biodistribution. , Journal of Controlled Release, 2012, 第 5 作者(12) PLGA-lecithin-PEG core-shell nanoparticles for cancer targeted therapy, Nano life, 2012, 第 5 作者(13) Toll-like receptor 3 agonist complexed with cationic liposome augments vaccine-elicited antitumor immunity by enhancing TLR3-IRF3 signaling and type I interferons in dendritic cells., Vaccine, 2012, 第 5 作者(14) Self-assembled cationic micelles based on PEG-PLL-PLLeu hybrid polypeptides as highly effective gene vectors., Biomacromolecules, 2012, 第 5 作者(15) Dual effects of interleukin-18: inhibiting hepatitis B virus replication in HepG2.2.15 cells and promoting hepatoma cells metastasis., Am J Physiol Gastrointest Liver Physiol. , 2011, 第 3 作者(16) The role of surface charge density in cationic liposome-promoted dendritic cell maturation and vaccine-induced immune responses., Nanoscale, 2011, 第 5 作者(17) Assessing the immunopotency of Toll-like receptor agonists in an in vitro tissue-engineered immunological model., Immunology, 2010, 第 1 作者(18) 不同表面电荷的阳离子脂质体对人外周血单核细胞活化和细胞活性的影响, 生物物理学报, 2010, 第 5 作者(19) An integrated microfluidic cell array for apoptosis and proliferation analysis induction of breast cancer cells., Biofluidics, 2010, 第 4 作者(20) Augmentation of antibody responses by retinoic acid and costimulatory molecules., Semin Immunol. , 2009, 第 3 作者(21) Toll-like receptor 3 ligand and retinoic acid enhance germinal center formation and increase the tetanus toxoid vaccine response., Clinical vaccine and Immunology, 2009, 第 1 作者(22) 纳米技术在癌症早期诊断和治疗中的研究与展望, Research advancement and prospects of nanotechnology in early diagnosis and treatment of cancer. , 癌症, 2009, 第 3 作者(23) Neonatal-age treatment with vitamin A delays postweaning vitamin A deficiency and increases the antibody response to T-cell dependent antigens in young adult rats fed a vitamin A-deficient diet., Journal of Nutrition, 2007, 第 2 作者(24) Retinoic acid and polyriboinosinic: polyribocytidylic acid stimulate robust anti-tetanus antibody production while differentially regulating type 1/type 2 cytokines and lymphocyte populations. , Journal of Immunology, 2005, 第 1 作者(25) The anti-tetanus immune response of neonatal mice is augmented by retinoic acid combined with polyriboinosinic:polyribocytidylic acid., Proc Natl Acad Sci U S A. , 2005, 第 1 作者(26) Opposing cytokine-specific effects of all trans-retinoic acid on the activation and expression of signal transducer and activator of transcription (STAT)-1 in THP-1 cells., Immunology, 2002, 第 2 作者
发表著作( 1 )维生素与激素, Vitamins and Hormones: Vitamin A and retinoic acid in the regulation of B-cell development and antibody production., ELSEVIER, 2011-03, 第 3 作者
科研活动
科研项目( 1 )靶向树突状细胞的复合型肿瘤纳米疫苗研究, 主持, 省级, 2009-08--2012-08( 2 )多功能纳米疫苗载体和佐剂系统研究, 主持, 省级, 2011-07--2014-06( 3 )量子点标记技术研究病毒侵染和宿主应答, 参与, 国家级, 2011-01--2015-08( 4 )肿瘤靶向性纳米载药和诊疗一体化技术研究, 参与, 省级, 2010-01--2012-12( 5 )基于智能化多糖纳米凝胶的肿瘤疫苗及抗肿瘤作用研究, 主持, 国家级, 2012-01--2015-12( 6 )基于智能化纳米材料的疫苗载体及肿瘤纳米疫苗关键技术研究, 主持, 省级, 2013-01--2014-12
参与会议(1)The role of surface charge in cationic liposome-induced antigen-presenting cell (APC) activation and viability. Y. Ma, X. Xie, Y. Zhuang, 2010-05-07(2)A novel low-toxic liposomal adjuvant: different liposome compositions regulate monocyte activation and viability Y. Ma, D. Zhou, X. Xie, 2009-11-24(3)Evaluating the immunoregulatory and reactogenic effects of therapeutic antibodies using the Modular IMmune In Vitro Construct (MIMIC?) Technology. Y. Ma, B. Schanen, L. Poisson, et al. 2009-05-22
合作情况
项目协作单位
指导学生
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