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中国科学院大学研究生导师简介-田志新

中国科学院大学 免费考研网/2016-05-09

田志新 男大连化学物理研究所
电子邮件:zhixintian@dicp.ac.cn
通信地址:辽宁省大连市中山路457号
邮政编码:116023


研究领域1. 气相离子化学
1) 离子结构测定
2) 光谱
3) 单分子解离
4) 离子-分子反应
5) 光解离
6) 分子轨道从头算

2.蛋白质组学
1)用top-down和bottom-up集成方法对整个蛋白体系进行表征
2)用top-down蛋白质组学方法对组蛋白进行高通量和高灵敏度表征
3) 用基于质谱的蛋白质组学的方法对不同生理条件下的蛋白质体系进行差异定性定量分析,致力于生物标志物的发现和确认
4)将蛋白质组学数据与其他组学数据集成,对差异蛋白或修饰进行机理和功能研究
5)蛋白质组学方法和科学发现在临床上的应用
6)蛋白质、多肽、及糖类的多维分离
7)蛋白质、多肽、及糖类的气相解离机制
8)生物信息学   


招生信息招收硕、博士研究生及博士后

招生专业 分析化学
物理化学(含:化学物理)
化学生物学

招生方向 蛋白质组学,糖组学
气相离子化学
生物信息学
教育背景 2000-09--2003-08 中国科学院化学研究所 博士
1997-09--2000-07 湖南师范大学 硕士
1993-09--1997-07 湖南师范大学 学士


学历博士研究生

学位博士

工作经历

工作简历 2011-09--今 中国科学院大连化学物理研究所 研究员
2008-08--2011-09 美国西北太平洋国家实验室 博士后
2004-03--2008-08 美国明尼苏达大学双城分校 博士后
2003-09--2004-03 中国科学院化学研究所 研究助理


社会兼职
教授课程
专利与奖励

奖励中国首批“青年****”引进人才,2011.10
中国科学院化学所青年科学奖优秀奖,2002.12
中国科学院化学所所长奖学金,2002.12


专利

出版信息

发表论文合作发表论文
1. L. Wang, U. K. Aryal, Z. Dai, A. C. Mason, M. E. Monroe, Z. Tian, J. Zhou, D. Su, K. K. Weitz, T. Liu, D. G. Camp, II, R. D. Smith, S. E. Baker, and W.-J Qian. Mapping N-Linked Glycosylation Sites in the Secretome and Whole Cells of Aspergillus niger Using Hydrazide Chemistry and Mass Spectrometry. Journal of Proteome Research, 2011, 11(1), 143-156.
2. Z. Tian, R. Zhao, N. Toli?, R. J. Moore, D. L. Stenoien, E. W. Robinson, R. D. Smith, L. Pa?a-Toli?. Two-Dimensional Liquid Chromatography System for Online Top-down Mass Spectrometry. Proteomics, 2010,10(20), 3610-3620. [Invited Contribution]
3. D. Lopez-Ferrer, K. Petritis, E. W. Robinson, K. K. Hixson, Z. Tian, J. H. Lee, S.-W. Lee, N. Toli?, K. K. Weitz, M. E. Belov, R. D. Smith, L. Pa?a-Toli?. Pressurized Pepsin Digestion in Proteomics: an Automatable Alternative to Trypsin for Integrated Top-Down Bottom-Up Proteomics. Molecular and Cellular Proteomics, 2010, mcp.M110.001479. [Invited Contribution]
4. Z. Tian, S. R. Kass. Gas-Phase versus Liquid-Phase Structures by Electrospray Ionization Mass Spectrometry. Angewandte Chemie-International Edition, 2009, 48(7), 1321-1323. [COMMUNICATIONS]
5. Z. Tian, A. Fattahi, L. Lis, S. R. Kass. Single-Centered Hydrogen-Bonded Enhanced Acidity (SHEA) Acids: A New Class of Br?nsted Acids. Journal of the American Chemical Society, 2009, 131(3), 1174-1181.
6. Z. Tian, X.-B. Wang, L.-S. Wang, S. R. Kass. Are Carboxyl Groups the most Acidic Sites in Amino Acids? Gas-Phase Acidities, Photoelectron Spectra, and Computations on Tyrosine, p-Hydroxybenzoic Acid, and Their Conjugate Bases. Journal of the American Chemical Society, 2009, 131(46), 16984-16988.
7. Z. Tian, A. Fattahi, L. Lis, S. R. Kass. Neutral Intramolecular Hydrogen-Bonded Bases. Croatica Chemica Acta, 2009, 82(1), 41-45. [Invited Contribution]
8. Z. Tian, B. Chan, M. B. Sullivan, L. Radom, S. R. Kass. Lithium Monoxide Anion: A Ground-State Triplet with the Strongest Base to Date. Proceedings of the National Academy of Sciences of the United States of America, 2008, 105(22), 7647-7651. [Highlight: Lithium Monoxide Anion Is As Basic As It Gets - LiO? is newly crowned as the most basic molecule known; it may be impossible to beat. Chem. Eng. News, 2008, 86(23), 10.]
9. Z. Tian, S. R. Kass. Does Electrospray Ionization Produce Gas-Phase or Liquid-Phase Structures? Journal of the American Chemical Society, 2008, 130(33), 10842-10843. [COMMUNICATIONS] [Highlight: Does Electrospray Ionization Produce Gas-Phase or Liquid-Phase Structures? Chem. Eng. News, 2008, 86(32), 38.]
10. K. W. Wiitala, Z. Tian, C. J. Cramer, T. R. Hoye. A Thermal Decarbonylation of Penam ?-Lactams. Journal of Organic Chemistry, 2008, 73(8), 3024-3031.
11. Z. Tian, L. Lis, S. R. Kass. Hydrogen-Deuterium Exchange and Selective Labeling of Deprotonated Amino Acids and Peptides in the Gas Phase. Journal of the American Chemical Society, 2008, 130(1), 8-9. [COMMUNICATIONS]
12. Z. Tian, S. R. Kass. A Redetermination of the Heats of Formation of Chloro- and Dichlorocarbene and the Deprotonation of Methyl Cation, A Spin Forbidden Process? International Journal of Mass Spectrometry, 2007, 267(1-3), 288-294.
13. Z. Tian, A. Pawlow, J. C. Poutsma, S. R. Kass. Are Carboxyl Groups the Most Acidic Sites in Amino Acids? Gas Phase Acidity, H/D Exchange Experiments, and Computations on Cysteine and It’s Conjugate Base. Journal of the American Chemical Society, 2007, 129(17), 5403-5407.
14. Z. Tian, A. Fattahi, L. Lis, S. R. Kass. Cycloalkane and Cycloalkene C–H Bond Dissociation Energies. Journal of the American Chemical Society, 2006, 128(51), 17087-17092.
15. A. Fattahi, L. Lis, Z. Tian, S. R. Kass. The Heat of Formation of Cyclobutadiene. Angewandte Chemie International Edition, 2006, 45, 4984-4988. [Highlight: Costs of Cyclobutadiene. Science, 2006, 313, 275.]
16. Z. Tian, Z. Tang. Experimental and Theoretical Studies on the Interaction of Silver Cluster Cations Agn+ (n = 1 ? 4) with Ethylene. Rapid Communications in Mass Spectrometry, 2005, 19, 2893-2904.
17. Z. Tian, W. Bi, H. Deng, X. Wang, Z. Tang, Q. Zhu. A Mini-TOF Photofragment Translational Spectrometer - Photofragmentation of Trifluoroiodomethane at 281.73 nm. Chemical Physics Letters, 2004, 400(1-3), 15-18.
18. T. Shi, X. Wang, Z. Tian, Q. Zhu. Ab Initio Studies on the Structures of the Hydrogen-Bond Clusters C5H10NH(NH3)n(n = 1 ? 3). Chemical Journal of Chinese Universities, 2004, 25 (1), 124-127.
19. X. Xing, Z. Tian, H. Liu, Z. Tang. Reactions Between M+ (M = Si, Ge, Sn and Pb) and Benzene in Gas Phase. Rapid Communications in Mass Spectrometry, 2003, 17(15), 1743-1748.
20. X. Xing, Z. Tian, H. Liu, Z. Tang. Magic Bimetallic Cluster Anions of M/Pb (M=Au, Ag and Cu) Observed and Analyzed by Laser Ablation and TOF Mass Spectrometry. Rapid Communications in Mass Spectrometry, 2003, 17(13), 1411-1415.
21. Z. Tian, X. Xing, Z. Tang. Reactions of Lead Cluster Ions with Acetone. Rapid Communications in Mass Spectrometry, 2003, 17(1), 17-23.
22. X. Xing, Z. Tian, H. Liu, Z. Tang. A Comparative Study of Cation and Anion Cluster Reaction Products: The Reaction Mechanisms of Lead Clusters with Benzene in Gas Phase. Journal of Physical Chemistry A, 2003, 107 (41), 8484-8491.
23. X. Wang, Z.Tian, T. Shi, X. Shi, D. Yang, Q. Zhu. High-Resolution Photofragment Translational Spectra of the Photodissociation of Trifluoroiodomethane at 248 nm. Chemcal Physics Letters, 2003, 380(5-6), 600-603.
24. Z. Tian, X. Xing, Z. Tang. Reactions of Lead Cluster Ions with Ethylene, Propene, Trans-butene, and Cis-butene. Rapid Communications in Mass Spectrometry, 2002, 16(16), 1515-1520.
25. T. Shi, X. Wang, X. Shi, Z. Tian, Q. Zhu. Proton Transfer in the [M×××H×××NH3]+ System (M = 1, 4-dioxane). Journal of Molecular Structure (Theochem), 2002, 578(1-3), 135-143.
26. X. Xing, Z. Tian, P. Liu, Z. Gao, Q. Zhu, Z. Tang. The Laser Reflectron Time-of-Flight Mass Spectrometer Used on Cluster Research. Chinese Journal of Chemical Physics, 2002, 15(2), 83-87.
27. J. Li, X. Wu, Z. Tian, J. Gong. Catalytic Synthesis of Ketal by Niobic Acid. Chinese Journal of Synthetic Chemistry, 2002, 10(1), 53-55.
28. Z. Tian, Y. Li, J. Li, J. Gong. Catalytic Synthesis of Sec-butyl Acetate by Niobic Acid. Fine Chemicals, 2000, 17(6), 334-335, 348.
29. Z. Tian, J. Gong, J. Li. Niobic Acid Catalysis in Acetal Reaction. Speciality Petrochemicals, 2000, (2), 23-25.
30. Z. Wu, J. Li, J. Gong, Z. Tian. Catalytic Synthesis of DnOP by Niobic Acid. Modern Chemical Industry, 2000, 20(2), 27-28, 30.
31. L. Zhang, Z. Tian, J. Gong, J. Li. Catalysis of Ketol Reaction by Niobic Acid. Fine Chemicals, 2000, 17(1), 30-31, 35.
32. Z. Tian, J. Li, J. Gong. Catalytic Synthesis of Ethyl Acetate with Niobic Acid in Liquid Phase. Chinese Journal of Synthetic Chemistry, 2000, 8(3), 260-263.
33. J. Li, L. Zhang, Z.Tian, J. Gong. Liquid-Phase Esterification Catalyzed by Niobic Acid. Chinese Journal of Synthetic Chemistry, 2000, 8(3), 194-196.
34. Z. Tian, Z. Wu, J. Li, J. Gong. Catalytic Synthesis of n-Butylacetate by Niobic Acid. SHANXI Chemical Industry, 1999, 28(3), 13-15.
35. S. Yu, Z. Tian, W. Ping. Catalytic Synthesis of ?-Butyl Phenylacetonitrile with Triethanol Amine. Modern Chemical Industry, 1999, 19(6), 30-31.
36. Z. Tian, S. Yu, J. Li. Catalytic Synthesis of 7,7-Dichlorodicyclo[4.1.0] Heptane with Triethanol Amine. Chinese Journal of Synthetic Chemistry, 1999, 7(3), 317-320.
37. Z. Tian, J. Li, J. Gong. Synthesis of Isopentyl Acetate Catalyzed by Niobic Acid. Acta Scientiarum Naturalium Universitatis Normalis Hunanensis, 1999, 22(3), 64-67.
38. Z. Tian, S. Yu, J. Li, L. Huang. Catalytic Synthesis of n-Butylphenylether with Triethanol Amine. SHANXI Chemical Industry, 1998, 27(4), 27-28.
邀请论文
1. Z.Tian, S. R. Kass. Organic Gas-phase Ion Chemistry. Annual Reports on the Progress of Chemistry. Section B, Organic Chemistry, 2006, 102, 290-324.


发表论著1. S. Wu, N. Toli?, Z. Tian, E. W. Robinson, and L. Pa?a-Toli?. An Integrated Top-Down and Bottom-Up Strategy for Broadly Characterizing Protein Isoforms and Modifications. Methods in Molecular Biology, Vol. 694 Bioinformatics for Comparative Proteomics, 2010, Springer.

科研活动

科研项目1. 中国科学院“青年****”科研启动经费
2.大连化学物理研究所创新经费
参与会议1. Z. Tian, R. Zhao, N. Toli?, R. J. Moore, D. L. Stenoien, E. W. Robinson, R. D. Smith, L. Pa?a-Toli?. Online Two-Dimensional Liquid Chromatography Characterization of Histones Using Top-Down Mass Spectrometry. 35th International Symposium on High Performance Liquid Phase Separations and Related Techniques, Boston, Massachusetts, USA, June 19 – 24, 2010.
2. Z. Tian, R. Zhao, N. Toli?, R. J. Moore, D. L. Stenoien, E. W. Robinson, R. D. Smith, L. Pa?a-Toli?. Top-down Characterization of Core Histones Using an Online Two-Dimensional Nanocapillary Liquid Chromatography System. 58th ASMS Conference on Mass Spectrometry and Allied Topics, Salt Lake City, Utah, USA, May 23 - 27, 2010.
3. Z. Tian, S. R. Kass. Gas-Phase H/D Exchange of Deprotonated Glycine Oligomers (Gly)n (n=1-6). 56th ASMS Conference on Mass Spectrometry and Allied Topics, Denver, Colorado, USA, June 1 - 5, 2008.
4. Z. Tian, S. R. Kass. Are Deprotonated Amino Acids All Carboxylates? 234th American Chemical Society Meeting & Exposition, Boston, Massachusetts, USA, August 19 - 23, 2007.
5. Z. Tian, S. R. Kass. H/D Exchange of Deprotonated Amino Acids and Peptides. 55th ASMS Conference on Mass Spectrometry and Allied Topics,Indianapolis, Indiana, USA, June 3 - 7, 2007.
6. Z. Tian, S. R. Kass. H/D Exchange and Equilibrium Acidities of Amino Acids and Peptides. Gordon Research Conference on Gaseous Ions: Structures, Energies & Reactions,Ventura, California, USA, February 25 – March 2, 2007.
7. Z. Tian, S. R. Kass. Hydrogen Deuterium Exchange Mechanism. 232nd American Chemical Society Meeting & Exposition, San Francisco, California, USA, September 10 - 14, 2006.
8. Z. Tian, S. R. Kass. Structure and Reactivity of Organolithium Compounds. 54th ASMS Conference on Mass Spectrometry and Allied Topics, Seattle, Washington, USA, May 28 – June 01, 2006.


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项目协作单位
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