1、招生信息2、教育背景3、工作经历4、教授课程5、专利与奖励6、出版信息7、科研活动8、合作情况9、指导学生
基本信息
王昊阳 男 汉族 硕导 上海有机化学研究所
电子邮件：haoyangwang@mail.sioc.ac.cn
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研究领域主要从事质谱学研究和表征均相催化反应中的活泼中间体，以及气相条件下单分子的骨架重拍反应。另外还从事与食品安全相关的质谱学研究工作。
招生信息招收硕士研究生
招生专业070303-有机化学
-分析化学
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招生方向 有机质谱学
分析化学
有机化学
教育背景1996.9-2000.7: 中国药科大学, 药物分析专业获学士学位; 2000.9-2003.7: 中国药科大学与上海有机所，药物分析专业获硕士学位，导师: 郭寅龙研究员和张正行教授; 2003.9-2006.6: 上海有机化学研究所, 分析化学专业获博士学位, 导师: 郭寅龙研究员。2006.7-2008.8: 德国奥尔登堡大学, 博士后, 导师: Jürgen O. Metzger教授, 2008.8-至今: 中科院上海有机化学研究所。




学历--博士 研究生


学位-- 博士


出国学习工作2006.7-2008.8: 德国奥尔登堡大学, 博士后, 导师: Jürgen O. Metzger教授，运用质谱学技术研究均相催化反应。
工作经历

工作简历

社会兼职
教授课程
专利与奖励

奖励信息

专利成果
出版信息

发表论文学术专著章节：
1. Rong Qian, Jing Zhou, Shengjun Yao, Haoyang Wang, Yinlong Guo. Reactive Intermediates: MS Investigations in Solution. Edited by Leonardo S. Santos WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim ISBN: 978-3-527-32351-7.
2. Hao-Yang Wang, Yin-Long Guo. Evaluating the Enantioselectivity of Catalytic Asymmetric Reactions and Screening Chiral Catalysts by ESI-MS. Book on chiral recognition/Taylor & Francis.

科研论文：
1. Jiapeng Leng, Haoyang Wang, Li Zhang, Jing Zhang, Yinlong Guo. Integration of High Accuracy N-terminus Identification in Peptide Sequencing and Comparative Protein Analysis via Isothiocyanate-based Isotope Labeling Reagent with ESI Ion-trap TOF MS. J. Am. Soc. Mass Spectrom. 2011, (in press).
2. Hao-Yang Wang*, Xu Chu, Zhi-Xiong Zhao, Xiao-Shuang He, Yin-Long Guo*. Analysis of Low molecular Weight compounds by MALDI-FTICR-MS. J. Chromatogr. B. 2011, (in press).
3. Hang Wang, Haoyang Wang, Li Zhang, Jing Zhang, Yinlong Guo. N-alkylpyridinium Isotope Quaternization for Matrix-Assisted Laser Desorption/Ionization Fourier Transform Mass Spectrometric Analysis of Cholesterol and Fatty Alcohols in Human Hair. Anal. Chim. Acta. 2011, 690, 1-9.
5. Chu Xu, Hao-Yang Wang*, Feng-Jun Zhu, Yin-Long Guo, Long Lu*. Studies of gas phase reactions of cationic iron complexes of 2-pyrimidinyloxy-N-arylbenzylamines by electrospray ionization tandem mass spectrometry. Rapid Commun. Mass Spectrom. 2011, 25(1), 169-178.
6. Jiapeng Leng, Haoyang Wang, Li Zhang, Jing Zhang, Yinlong Guo. Application of Tandem Mass Spectra for the Peaks of Isotope Pattern in the Elemental Composition Assignment of Product Ions. Chin. J. Chem. 2010, 28(9), 1751-1756.
7. Chu Xu, Hao-Yang Wang, Zhi-Xiong Zhao, Qing-Hong Tang, Yin-Long Guo, Long Lu. Studies of the Interesting Gas-phase Rearrangement Reactions of 2-Pyrimidinyloxy-N-arylbenzylurea Promoted by Urea-Carbamimidic Acid Tautomerism by ESI-MS/MS and Theoretical Computation. Chin. J. Chem. 2010, 28(9), 1765-1772.
8. 赵志雄, 姚胜军, 王昊阳*, 郭寅龙*. 电喷雾质谱法研究不对称催化反应进展. 有机化学, 2010, 30(6), 809-815.
9. Zhi-Xiong Zhao, Hao-Yang Wang*, Chu Xu, Yin-Long Guo*. Gas Phase Synthesis of Hydrodiphenlycyclopropenylium Via Nonclassical Favorskii Rearrangement from Alkali Cationized α,α'-Dibromodibenzyl Ketone. Rapid Commun. Mass Spectrom. 2010, 24(17), 2665-2672.
10. Jing Zhou, Qian Zhao, Wen-Wen Chen, Haoyang Wang, Guo-Qiang Lin, Ming-Hua Xu, Yinlong Guo. Studies on Gas-phase Cyclometalations of [ArNi(PPh3)n]+ (n=1 or 2) by Electrospray Ionization Tandem Mass Spectrometry. J. Am. Soc. Mass Spectrom. 2010, 21(7), 1265-1274.
11. Zhe Xu, Hao-Yang Wang, Shi-Xin Huang, Yuan-Long Wei, Sheng-Jun Yao, Yin-Long Guo. Determination of β-Lactamases Residues in Milk Using Matrix-assisted Laser Desorption/ionization Fourier Transform Mass Spectrometry. Anal. Chem., 2010, 82(5), 2113-2118.
12. Li-Min Zeng, Hao-Yang Wang, Yin-Long Guo. Fast Quantitative Analysis of Boric Acid by Gas Chromatography-Mass Spectrometry Coupled with a Simple and Selective Derivatization Reaction Using Triethanolamine. J. Am. Soc. Mass Spectrom. 2010, 21(3), 482-485.
13. Hao-Yang Wang, Wai-Leung Yim, Thorsten Klüner, Jürgen O. Metzger. ESI-MS Studies and Calculations on Alkali Metal Adduct Ions of Ruthenium Olefin Metathesis Catalysts and Their Catalytic Activity in Metathesis Reactions. Chem. Eur. J. 2009, 15, 10948-10959.
14.Fang Fang, Ping Liu, Haoyang Wang, Li Zhang, Jing Zhang, Yuping Gao, Liming Zeng, Yinlong Guo. Studies Of Keratins In Tongue Coating Samples of HepatitisB Patients By Mass Spectrometry. Rapid Commun. Mass Spectrom. 2009, 23, 1703-1709.
15. Cesar A. Marquez, Haoyang Wang, Francesco Fabbretti, Ju？rgen O. Metzger. Electron-Transfer-Catalyzed Dimerization of Trans-Anethole: Detection of the Distonic Tetramethylene Radical Cation Intermediate by Extractive Electrospray Ionization Mass Spectrometry. J. Am. Chem. Soc. 2008, 130, 17208-17209.
16. Haoyang Wang, Jürgen O. Metzger. ESI-MS Study on First Generation Ruthenium Olefin Metathesis Catalysts in Solution: Direct Detection of the Catalytically Active 14-Electron Ruthenium Intermediate. Organometallics. 2008, 27, 2761-2766.
17. Xiang Zhang, Haoyang Wang, Yuanxi Liao, Houwei Ji, Yinlong Guo. Study of Methylation of Nitrogen-Containing Compounds in the Gas Phase. J. Mass Spectrom. 2007, 42, 218-224.
18. Hao-Yang Wang, Qing Hong Tang, Xiang Zhang, Yin-Long Guo, Long Lu. Using Tandem Mass Spectrometry to Predict Chemical Transformations of 2-Pyrimidinyloxy-N-arylbenzyl Amine Derivatives in Solution. J. Am. Soc. Mass Spectrom. 2006, 17, 253-263.
19. Hao-Yang Wang, Xiang Zhang, Rong Qian, Yin-Long Guo, Long Lu. Gas-phase Sulfonyl-Sulfinate Rearrangement of Protonated 4, 6-Dimethoxy-2-(methylsulfonyl) Pyrimidine. Rapid Commun. Mass Spectrom. 2006, 20, 2773-2776.
20. Hao-Yang Wang, Xiang Zhang, Yin-Long Guo, Long Lu. Mass Spectrometric Studies of the Gas Phase Retro-Michael Type Fragmentation Reactions of 2-Hydroxybenzyl-N-Pyrimidinylamine Derivatives. J. Am. Soc. Mass Spectrom. 2005, 16, 1561-1573.
21. Zhang Xiang, Haoyang Wang, Yinlong Guo. Interception of the Radicals Produced in Electrophilic Fluorination with Radical Traps (Tempo, Dmpo) Studied by Electrospray Ionization Mass Spectrometry. Rapid Commun. Mass Spectrom. 2006, 20, 1877-1882.
22. Jianping Xie, Shihao Sun, Haoyang Wang, Yongli Zong, Cong Nie, Yinlong Guo. Determination of Nicotine in Mainstream Smoke on the Single Puff Level by Liquid-Phase Microextraction Coupled to Matrix-Assisted Laser Desorption/Ionization Fourier Transform Mass Spectrometry. Rapid Commun. Mass Spectrom. 2006, 20, 2573-2578.
23. Rong Qian, Hao Guo, Yuan-Xi Liao, Haoyang Wang, Xiang Zhang and Yinlong Guo. Studies of Gas-phase Fragmentation Reactions of [Pd(PPh3)2(OCOR)]+ by Electrospray Ionization Fourier transform Ion Cyclotron Resonance Mass Spectrometry. Rapid Commun. Mass Spectrom. 2006, 20, 589-594.
24. Zhi-Hong Cheng, Yin-Long Guo, Hao-Yang Wang, Guo-Qiang Chen. Qualitative and Quantitative Analysis of Quaternary Ammonium Alkaloids from Rhizoma Corydalis by Matrix-Assisted Laser Desorption/Ionization Fourier Transform Mass Spectrometry Coupled with a Selective Precipitation Reaction Using Reinecke Salt. Anal. Chim. Acta. 2006, 555, 269-277.
25. Hao-Yang Wang, Xiang Zhang, Yin-Long Guo, Xi-Cheng Dong, Qing-Hong Tang, Long Lu. Sulfonamide Bond Cleavage in Benzenesulfonamides and Rearrangement of the Resulting p-Aminophenylsulfonyl Cations: Application to a 2-Pyrimidinyl-oxy-benzylaminobenzene sulfonamide Herbicide. Rapid Commun. Mass Spectrom. 2005, 19, 1696-1702.
26. Hao-Yang Wang, Yuan-Xi Liao, Yin-Long Guo, Qing-Hong Tang, Long Lu. Interesting Acid Catalyzed O-N-Type Smiles Rearrangement Reactions of 2-Pyrimidinyloxy-N-Arylbenzylamine Derivatives. SynLett. 2005, 8, 1239-1242.
27. Hao-Yang Wang, Yin-Long Guo, Zhen-Xing Zhang, Deng-Kui An. Fast Analysis of Volatile Compounds in Essences by Headspace-Solid Phase Micro-Extraction Gas Chromatography-Mass Spectrometry. Chinese J. Anal. Chem. 2005, 33, 245-247.
28. Jing Zhang, Hao-Yang Wang, Yin-Long Guo. Amino Acids Analysis by MALDI Mass Spectrometry Using Carbon Nanotubes as Matrix. Chinese Journal of Chemistry. 2005, 23, 185-189.
29. Yue Su, Hao-Yang Wang, Yin-Long Guo,Bing-Ren Xiang, Deng-Kui An. Effect of Damping Mechanisms on Mass Calibration Equation for MALDI/FTMS. Chinese Journal of Chemistry. 2005, 23, 1053-1059.
30. Xiang Zhang, Yuanxi Liao, Rong Qian, Haoyang Wang, Yinlong Guo. Investigation of Radical Cation in Electrophilic Fluorination by ESI-MS. Org. Lett. 2005, 7, 3877-3880.
31. Shihao Sun, Zhihong Cheng, Jianping Xie, Jianxun Zhang, Yuanxi Liao, Haoyang Wang, Yinlong Guo. Identification of Volatile Basic Components in Tobacco by HS-LPME Coupled to MALDI-FTMS. Rapid Commun. Mass Spectrom. 2005, 19, 1025-1030.
32. Hao-Yang Wang, Yin-Long Guo, Long Lu. Studies of Rearrangement Reactions of Protonated and Lithium Cationized 2-Pyrimidinyloxy-N-arylbenzylamine Derivatives by MALDI-FTICR MS. J. Am. Soc. Mass Spectrom. 2004, 15, 1820-1832.
33. Hao-Yang Wang, Yin-Long Guo. Simple and Rapid Analysis for Studies of the Volatile Flavor Compounds in the Rhizomas of Two Species Rhodiolas by Headspace Gas Chromatography-Tandem Mass Spectrometry. Anal. Lett. 2004, 37, 2151-2161.
34. Shi-Fang Ren, Hao-Yang Wang, Yin-Long Guo. Chiral Molecular Recognition of Cyclodextrin to Tropine by Electrospray Fourier Transform Ion Cyclotron Resonance Mass Spectrometry. Acta Chimica Sinica. 2004, 62, 1959-1962.
35. Hao-Yang Wang, Yin-Long Guo; Liang Zhang, Deng-Kui An. Progress in Researches on Gas-phase SN2 Ion-Molecule Reaction by Mass Spectrometry. Chinese J. Org. Chem. 2002, 22, 974-980.
36. 郭寅龙, 王昊阳, 张祥, 钱荣. 质谱法研究有机反应活泼中间体. 质谱学报 , 2006, 27 (增刊), 63-64.
37. 王昊阳, 张祥, 郭寅龙. 串联质谱法研究2-嘧啶氧基-N-芳基苄胺类衍生物的气相化学反应. 中国药科大学学报. 2006, 37, 379-384.
38. 苏越, 王昊阳, 郭寅龙, 相秉仁, 安登魁. 人工神经网络用于FTMS准确质量测定, 质谱学报. 2006, 27, 11-16.
39. 王昊阳, 郭寅龙, 关大鹏, 董艳苓. 静态顶空-毛细管气相色谱法同时测定氢化可的松中七种微量的有机挥发性杂质. 药物分析杂志, 2005, 25, 846-848.
40. 廖远熹, 王昊阳, 郭寅龙, 邵应男. 静态顶空-气相色谱-质谱分析中药柴胡的挥发性成分, 质谱学报. 2005, 26, 187-192.
41. 廖远熹, 程志红, 王昊阳, 郭寅龙, 邵应男. 静态顶空-气相色谱-质谱联用鉴别硫磺熏制的柴胡, 中国中药杂志. 2005, 30, 1909-1911.
42. 王昊阳, 郭寅龙, 张正行, 安登魁. 自动化静态顶空-气相色谱-质谱对天然香精中挥发性成分的研究. 分析测试学报. 2004, 23, 9-13.
43. 王昊阳, 郭寅龙, 张正行, 安登魁. 静态顶空与顶空-SPME-气质谱联用法在烟用香料分析中的比较. 分析测试学报. 2004, 23 ,115-117.
44. 程志红, 陈国强, 王昊阳, 郭寅龙. 延胡索中季胺生物碱的高分辨基质辅助激光解吸电离质谱研究.中国天然药物研究. 2004, 2 ,99-102.
45. 廖远熹, 王昊阳, 郭寅龙. 复方祛风湿止痛药粉末中挥发性成分的静态顶空-气相色谱-质谱分析. 分析测试技术与仪器. 2004, 10 ,145-150.
46. 王昊阳, 郭寅龙, 张正行, 安登魁. 顶空-气相色谱法进展. 分析测试技术与仪器. 2003, 9,129-135.
47. 潘峰云, 张亮 ,王林波, 王昊阳. HPLC法测定人血浆中丙硫氧嘧啶及药代动力学研究.中国药科大学学报. 2001, 32, 363-366.

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