1、招生信息2、教育背景3、工作经历4、教授课程5、专利与奖励6、出版信息7、科研活动8、合作情况9、指导学生
基本信息
王柳 女 硕导 中国科学院动物研究所
电子邮件: wangliu@ioz.ac.cn
通信地址: 北京市朝阳区北辰西路1号院5号
邮政编码: 100101
研究领域
招生信息
招生专业085238
招生方向动物克隆
教育背景1998-09--2001-07 中国农业科学院研究生院 博士学位1995-09--1997-07 东北农业大学 硕士学位1987-09--1991-07 东北农业大学 学士学位
学历
学位
工作经历
工作简历2003-06~现在, 中国科学院动物研究所, 副研究员2001-07~2003-06,北京大学 生命科学学院, 博士后1998-09~2001-07,中国农业科学院研究生院, 博士学位1996-01~2001-07,中国农业科学院哈尔滨兽医研究所, 助理研究员1995-09~1997-07,东北农业大学, 硕士学位1991-07~1995-12,中国农业科学院哈尔滨兽医研究所, 研究实习员1987-09~1991-07,东北农业大学, 学士学位
社会兼职
教授课程
专利与奖励
奖励信息(1)中国科学院杰出科技成就奖,院级,2013
专利成果( 1 )Key Genes, microRNAs, other non-coding RNAs and combination thereof for identifying and regulating the pluripotent status of cells,2012,第 3 作者,专利号: PCT/CN10/71622( 2 )一种提高体细胞重编程效率的方法,2011,第 2 作者,专利号: ZL 2008 1 **.7( 3 )一种动物胚胎干细胞系及其制备方法和应用,2012,第 4 作者,专利号: PCT/CN2012/074767( 4 )诱导型神经干细胞的制备方法及应用,2011,第 4 作者,专利号: **0.2
出版信息
发表论文(1) Efficient generation of mouse ESCs-like pig induced pluripotent stem cells. , Protein Cell , 2014, 第 5 作者(2) Epigenetic reprogramming, gene expression and in vitro development of porcine SCNT embryos are significantly improved by a histone deacetylase inhibitor—m- carboxycinnamic acid bishydroxamide (CBHA). , Protein Cell , 2014, 第 5 作者(3) Genetic modification and screening in the rat using haploid embryonic stem cells. , Cell Stem Cell., 2014, 第 5 作者(4) Derivation of androgenetic embryonic stem cells from m-carboxycinnamic acid bishydroxamide (CBHA) treated androgenetic embryos. , Chinese Science Bulletin, 2013, 第 5 作者(5) Stem cells and small molecule screening: haploid embryonic stem cells as a new tool. , Acta Pharmacologica Sinica, 2013, 第 3 作者(6) Tex101 is essential for male fertility by affecting sperm migration into the oviduct in mice. , J Mol Cell Biol, 2013, 第 5 作者(7) Generation of Transgenic Rats through Induced Pluripotent Stem Cells. , J Biol Chem., 2013, 第 5 作者(8) MicroRNA-323-3p Regulates the Activity of Polycomb Repressive Complex 2 (PRC2) via Targeting the mRNA of Embryonic Ectoderm Development (Eed) Gene in Mouse Embryonic Stem Cells. , J Biol Chem., 2013, 第 5 作者(9) Identification of a small molecule 1,4-bis-[4-(3-phenoxy-propoxy)-but-2-ynyl]-piperazine as a novel inhibitor of the transcription factor p53. , Acta Pharmacologica Sinica, 2013, 第 5 作者(10) Tbx3 and Nr5α2 Play Important Roles in Pig Pluripotent Stem Cells. , Stem Cell Rev and Rep. , 2013, 第 5 作者(11) Parthenogenetic haploid embryonic stem cells produce fertile mice. , Cell Research, 2013, 第 5 作者(12) Androgenetic haploid embryonic stem cells produce live transgenic mice. , Nature , 2012, 第 5 作者(13) Early patterning of cloned mouse embryos contributes to post-implantation development. , Developmental Biology., 2012, 第 5 作者(14) Generation of dopaminergic neurons directly from mouse fibroblasts and fibroblast-derived neural progenitors. , Cell Research., 2012, 第 5 作者(15) Rapid conversion of human ESCs into mouse ESC-like pluripotent state by optimizing culture conditions. , Protein and Cell , 2012, 第 5 作者(16) Generation of tripotent neural progenitor cells from rat embryonic stem cells. , Journal of Genetics and Genomics , 2012, 第 5 作者(17) Meta-analysis of the association between hOGG1 Ser326Cys polymorphism and risk of colorectal cancer based on case--control studies. , J Cancer Res Clin Oncol. , 2012, 第 5 作者(18) A novel variant of Oct3/4 gene in mouse embryonic stem cells. , Stem Cell Research., 2012, 第 5 作者(19) Direct reprogramming of setoli cells into multipotent neural stem cells by defined factors. , Cell Research, 2011, 第 5 作者(20) Mice generated from tetraploid complementation competent iPS cells show similar developmental features as those from ES cells but are prone to tumorigenesis. , Cell Research, 2011, 第 5 作者(21) Microinjection manipulation resulted in the increased apoptosis of spermatocytes in testes from intracytoplasmic sperm injection (ICSI) derived mice. , PLoS ONE, 2011, 第 5 作者(22) iPS cells generated without c-Myc have active Dlk1-Dio3 region and are capable of producing full-term mice through tetraploid complementation. , Cell Research, 2011, 第 5 作者(23) Mouse cloning and somatic cell reprogramming using electrofused blastomeres. , Cell Research, 2011, 第 5 作者(24) Dlk1-Dio3 region and are capable of producing full-term mice through tetraploid complementation., Cell Research, 2011, 第 5 作者(25) Pluripotency maintenance in mouse somatic cell nuclear transfer embryos and its 3 improvement by treatment with the histone deacetylase inhibitor TSA., Cellular Reprogramming., 2011, 第 3 作者(26) Viable Fertile Mice Generated from Fully Pluripotent iPS Cells Derived from Adult Somatic Cells. ., Stem Cell Rev, 2010, 第 5 作者(27) Successful generation of cloned mice using nuclear transfer from induced pluripotent stem cells. , Cell Research, 2010, 第 5 作者(28) Somatic nucleus reprogramming is significantly improved by m-carboxycinnamic acid bishydroxamide (CBHA), a histone deacetylase inhibitor. , J Biol Chem., 2010, 第 5 作者(29) HSPC117 deficiency in cloned embryos causes placental abnormality and fetal death. , Biochemical and Biophysical Research Communications., 2010, 第 5 作者(30) Activation of the imprinted Dlk1-Dio3 region correlates with pluripotency levels of mouse stem cells. , J Biol Chem., 2010, 第 5 作者(31) Efficient and rapid generation of induced pluripotent stem cells using alternative culture medium. , Cell Research , 2010, 第 5 作者(32) Derivation of embryonic stem cells from Brown Norway rats blastocysts. , Journal of Genetics and Genomics, 2010, 第 4 作者
发表著作
科研活动
科研项目( 1 )临床级干细胞分离、培养和建系研究, 主持, 国家级, 2011-01--2015-12( 2 )灵长类多能性干细胞的鉴定, 主持, 国家级, 2012-01--2016-08( 3 )干细胞向心肌细胞和肝细胞定向分化与重编程中重要表观遗传蛋白及复合物的筛选与功能研究, 参与, 国家级, 2011-01--2015-08
参与会议
合作情况
项目协作单位
指导学生
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