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中国科学院大学研究生导师简介-王新峦

中国科学院大学 免费考研网/2016-05-09

1、招生信息2、教育背景3、工作经历4、教授课程5、专利与奖励6、出版信息7、科研活动8、合作情况9、指导学生
基本信息
王新峦 女 硕导 中国科学院深圳先进技术研究院
电子邮件: xl.wang@siat.ac.cn
通信地址: 深圳市南山区西丽大学城学苑大道1068号
邮政编码: 518055
研究领域
招生信息

招生专业100104


招生方向骨靶向中药制剂治疗骨疾病

教育背景2003-08--2008-06 沈阳药科大学 博士学位
1999-08--2003-06 沈阳药科大学 学士学位


学历

学位
工作经历

工作简历2011-05~现在, 中国科学院深圳先进技术研究院, 副研究员
2009-04~2011-03,香港中文大学矫形外科及创伤学系, 博士后
2007-04~2009-03,香港中文大学矫形外科及创伤学系, 助理研究员
2003-08~2008-06,沈阳药科大学, 博士学位
1999-08~2003-06,沈阳药科大学, 学士学位


社会兼职
教授课程
专利与奖励

奖励信息(1)抗骨质疏松传统中药现代化研究及其应用,部委级,2013


专利成果( 1 )植物淫羊藿活性成分淫羊藿素的提取与预防激素性骨坏死的研发,2008,第 4 作者,专利号: US61/197319
( 2 )携载缓释天然小分子淫羊藿素的快速成形骨支架的研发,2008,第 4 作者,专利号: US61/125378
( 3 )Novel injectable bone targeted liposome formulation for delivering icaritin to bone formation surface for bone anabolic therapy,2011,第 5 作者,专利号: US61/625510
( 4 )骨靶向脂质体及其制备方法,2012,第 5 作者,专利号: PCT/CN2012/081355

出版信息

发表论文(1) Src blockage prevents destructive repair in steroid-associated osteonecrosis., JBMR, 2015, 第 5 作者
(2) In vivo Screening for Anti-osteoporotic Fraction from Extract of Herbal Formula Xianlinggubao in Ovariectomized Mice. , PlosOne, 2015, 第 1 作者
(3) Systemic Drug Delivery Systems for Bone Tissue Regeneration – A Mini Review., Current Pharmaceutical Design, 2015, 第 1 作者
(4) Src blockage by siRNA inhibits VEGF-induced vascular hyperpemeability and osteoclast activity - an in vitro mechanism study for preventing destructive repair of osteonecrosis., Bone, 2014, 第 5 作者
(5) Dual effects of puerarin on promoting osteogenesis and inhibiting adipogenesis-an in vitro efficacy and mechanistic study., Chinese Medicine, 2013, 第 5 作者
(6) Phytoestrogenic molecule desmethylicaritin suppressed adipogenesis via Wnt/β-catenin signaling pathway. , European Journal of Pharmacology, 2013, 第 1 作者
(7) Exogenous Phytoestrogenic Molecule Icaritin Incorporated into a Porous Scaffold for Enhancing Bone Defect Repair. , J Orthop Res., 2012, 第 1 作者
(8) Comparative study of osteogenic potential of a composite scaffold incorporating either endogenous bone morphogenetic protein-2 or exogenous phytomolecule icaritin: An in vitro efficacy study. , Acta Biomater. , 2012, 第 2 作者
(9) Promotion of bone repair by implantation of cryopreserved bone marrow-derived mononuclear cells in a rabbit model of steroid-associated osteonecrosis, Arthritis and rheumatism , 2012, 第 2 作者
(10) Icaritin, an Exogenous Phytomolecule, Enhances Osteogenesis but Not Angiogenesis—An In Vitro Efficacy Study., PlosOne, 2012, 第 3 作者
(11) Osteogenic Effects of Flavonoid Aglycones from an Osteoprotective Fraction of Drynaria fortunei – An In Vitro Efficacy Study, Phytomedicine, 2011, 第 1 作者
(12) Biodegradable CaMgZn bulk metallic glass for potential skeletal application, Acta Biomaterialia, 2011, 第 4 作者
(13) Flavonol Glycosides from Epimedium pubescens, Chemical and Pharmaceutical Bulletin, 2011, 第 4 作者
(14) Impaired bone healing in rabbits with steroid-induced osteonecrosis, JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, 2011, 第 2 作者
(15) Triterpenoid saponins from Dipsacus asperoides and their activity research in vitro, Journal of Asian Natural Products Research, 2011, 第 2 作者
(16) Promoted repair of steroid-associated osteonecrosis by implantation of cryopreserved bone marrow mononuclear cells in a rabbit model, Arthritis and Rheumatism, 2011, 第 2 作者
(17) Total flavonoid fraction of the Herba epimedii extract suppresses urinary calcium excretion and improves bone properties in ovariectomised mice, BRITISH JOURNAL OF NUTRITION , 2011, 第 3 作者
(18) Phenylpropanoid and flavonoids from osteoprotective fraction of Drynaria fortune, Nature Product Research, 2010, 第 1 作者
(19) Icariin protects against bone loss induced by oestrogen de?ciency and activates oestrogen receptor-dependent osteoblastic functions in UMR 106 cells, British Journal of Pharmacology, 2010, 第 5 作者
(20) A new compound with anti-oxidative activity from Seeds of Jatropha curcas, Chinese Herbal Medicines, 2010, 第 2 作者
(21) Structural and degradation characteristics of an innovative porous PLGA/TCP scaffold incorporated with bioactive molecular icaritin, Biomedical Materials, 2010, 第 2 作者
(22) Naringin improves bone properties in ovariectomized mice and exerts oestrogen-like activities in rat osteoblast-like (UMR-106) cells, British Journal of Pharmacology, 2010, 第 2 作者
(23) Constitutional flavonoids derived from Epimedium dose-dependently reduce incidence of steroid-associated osteonecrosis not via direct action by themselves on potential cellular targets, Plos One, 2009, 第 1 作者
(24) Two new flavonol glycosides from Epimedium Koreanum Nakai, Journal of Asian Natural products, 2009, 第 2 作者
(25) Fabrication of a two-level tumor bone repair biomaterial based on a rapid prototyping technique, Biofabrication, 2009, 第 2 作者
(26) A novel osteoprotective semisynthetic small molecule: icaritin inhibits both thrombosis and lipid-deposition for reducing incidence of experimental steroid-associated osteonecrosis in a dose-dependent manner, Bone, 2009, 第 4 作者
(27) Epimedium-derived flavonoids promote osteoblastogenesis and suppress adipogenesis in bone marrow stromal cells while exerting an anabolic effect on osteoporotic bone, Bone, 2009, 第 4 作者
(28) Antiosteoporotic Flavonoids from Drynaria Fortunei (Kunze) J. Sm. , Chemistry and Pharm Bulletin, 2008, 第 1 作者


发表著作
科研活动

科研项目( 1 )VEFG-Src信号阻断预防激素性骨坏死性骨修复的基础研究, 参与, 国家级, 2012-01--2015-12
( 2 )PLGA/TCP/Icariin复合骨生物材料制备及生物性能评估, 参与, 省级, 2011-01--2012-12
( 3 )预防骨质疏松中药“仙灵骨葆胶囊”的二次开发, 参与, 国家级, 2011-01--2013-12
( 4 )基于新型快速成型技术构建的活性骨修复材料修复难治愈性骨缺损的研究 , 参与, 国家级, 2013-02--2016-01
( 5 )GSK-3β/β-catenin信号通路介导的淫羊藿素预防绝经后骨质疏松的机制研究, 主持, 国家级, 2014-01--2016-12
( 6 )含中药分子的递送系统治疗骨性关节炎的研究, 主持, 国家级, 2015-05--2018-04


参与会议(1)Epimedium-Derived Flavonoids Reduce Incidence of Steroid-Associated OsteonecorsisviaTheir Metabolite(s) in vivo 第一届国际华人骨研学会(ICMRS)-美国骨矿研究学会(ASBMR)国际华人骨科研究大会 Wang Xinluan, Zheng Lizhen, Wang Nan, Cao Huijuan, Zhang Ge, Qin Ling 2013-05-22

合作情况

项目协作单位
指导学生

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