1、教育背景2、教授课程3、出版信息4、科研活动5、合作情况6、指导学生7、工作经历8、招生信息9、工作经历10、奖励信息
基本信息
游静 女 博导 广州地球化学研究所
电子邮件：youjing@gig.ac.cn
通信地址：广州市天河区科华街511号
邮政编码：510640


简介1996年毕业于长春地质学院，2000年在中科院兰州化学物理研究所获分析化学博士学位后赴美，在南伊利诺伊大学从事分析化学与水生毒理学的研究，2007年任美国中密苏里大学分析化学助理教授。2008年入选中国科学院“百人计划”，并于2009年1月正式到位工作。2012年获得国家自然科学基金委优秀青年基金资助，目前担任国际环境毒理与化学协会（SETAC）亚太分会理事、沉积物咨询委员会成员、国际环境毒理学主流刊物Envion Toxicol Chem 副主编和 Integ Environ Assess Manag 编委、美国南伊利诺伊大学动物系兼职研究生导师。

长期从事水环境中毒害污染物的生态毒性风险评估的研究，在沉积物中有机污染物的生物可利用性、毒性效应及混合污染物的毒性评价和鉴定（TIE）开展了大量工作。发现野生鲟鱼（密西西比河为研究区域）性别中性化与有机氯农药等内分泌干扰物对鱼类的早期暴露的相关性，阐明了沉积物中拟除虫菊酯类农药残留分布与底栖无脊椎动物毒性间的联系，并在此基础上进行了以毒性协同效应和温度效应为基础的毒代动力学和TIE的研究。相关研究被国际环境科学界权威杂志 Environ. Sci. Technol.作为封面文章进行了专门报道（ES&T 2005, 39, 497A）。近期研究发现氯氰菊酯是珠江三角洲城市区域水体沉积物的主要农药残留，且具有高生态毒性风险。已在Environ. Sci. Technol.和Environ. Toxicol. Chem.等SCI杂志上发表论文83篇（第一/通讯作者54篇），SCI论文他引900余次。获得国际环境毒理与化学协会（SETAC）与英国皇家化学协会（RSC）联合颁发的2011年度“SETAC/RSC奖”。目前工作重点是水体沉积物中以农药残留为代表的毒害污染物的生物可利用性和生态风险的评估技术的研究及其应用。

欢迎有志于从事污染物毒性风险评估研究的学生联系。
教育背景 1995-09--2000-12 中国科学院兰州化学物理研究所 博士（分析化学）
1992-09--1996-07 长春地质学院 学士（化学）


学位2000 中国科学院兰州化学物理研究所 -- 博士
1996 长春地质学院 -- 学士


出国学习工作2002-2007年 在美国南伊利诺伊州立大学化学系和动物系任博士后研究人员、
助理科学家、副科学家、研究顾问和兼职研究生导师（至今），
从事液相色谱检测器研制以及水生毒理与毒代动力学研究。
2007-2009年 美国中密苏里州立大学化学系任助理教授，主要从事有机污染物
环境行为和生物可利用性研究。

教授课程 有机污染物迁移与风险评估
出版信息

发表论文（2011-）1. Chen X.^s, Li H. -Z., You J.* Joint toxicity of sediment-associated permethrin and cadmium to Chironomus dilutus: The role of bioavailability and enzymatic activities, Environmental Pollution, 2015, 207, 138–1441.
2. Qi H.-X.^s, Ma P.^s, Li H.-Z., You J.* Assessment of sediment risk in the north end of Tai Lake, China: Integrating chemical analysis and chronic toxicity testing with Chironomus dilutus. Archives of Environmental Contamination and Toxicology, 2015, DOI: 10.1007/s00244-015-0162-7
3. Yi X.-Y.^s, Li H.-Z., Ma P.^s, You J.* Identifying the causes of sediment-associated toxicity in urban waterways in South China: Incorporating bioavailability-based measurements into whole-sediment toxicity identification evaluation. Environmental Toxicology and Chemistry, 2015, 34, 1744–1750
4. Qi H.-X.^s, Li H.-Z., Ma P.^s, You J.* Integrated sediment quality assessment through biomarker responses and bioavailability measurements: Application in Tai Lake, China. Ecotoxicology and Environmental Safety, 2015, 119, 148–154
5. Li H.-Z.^s, You J.* Application of species sensitivity distribution in aquatic probabilistic ecological risk assessment of cypermethrin: A case study in an urban stream in South China, Environmental Toxicology and Chemistry, 2015, 34, 640-648
6. Wang F.^p, Pei Y.-Y.^s, You J.* Biotransformation of DDT in benthic polychaete Nereis succinea: Quantitative estimation by analyzing the partitioning of chemicals between gut fluid and lipid. Environmental Toxicology and Chemistry, 2015, 34, 360-368
7. Wang F.^p, Qi H.-X.^s, You J.* Joint toxicity of sediment-associated DDT and copper to a polychaete, Nereis succinea. Ecotoxicology, 2015, 24, 424-432
8. Sun B.-Q.^s, Wang F.^p,*, Li H.-Z., You J. Occurrence and toxicity of sediment-associated contaminants in Guangzhou College City and its adjacent areas: The relationship to urbanization, Archives of Environmental Contamination and Toxicology, 2015, 68, 124–131
9. Li H.-Z.^s, Zhang B.-Z.^p, Wei Y.-L.^s, Wang F.^p, Lydy M.J., You J.* Bioavailability of highly hydrophobic organohalogen flame retardants from sediment: Application of bioaccumulation kinetics and passivesampling techniques, Environmental Science & Technology, 2014, 48, 6957-6964
10. Li H.-Z.^s, Zeng E.Y., You J.* Mitigating pesticide pollution in China requires law enforcement, farmer training and technological innovation. Environmental Toxicology and Chemistry, 2014, 33, 963-971
11. Li H.-Z.^s, Wei Y.-L.^s, Lydy M.J., You J.* Inter-compartmental transport of organophosphate and pyrethroid pesticides in South China: Implications for regional risk assessment. Environmental Pollution, 2014, 190, 19-26
12. Du J.^s, Li Y.-L.^s, Huang C., You J.* Chronic toxicity thresholds for sediment-associated benzo[a]pyrene in the midge (Chironomus dilutus), Archives of Environmental Contamination and Toxicology, 2014, 66, 370-378
13. Li H.-Z.^s, Ma H.-Z., Lydy M.J., You J.* Occurrence, seasonal variation and inhalation exposure of atmospheric organophosphate and pyrethroid insecticides in an urban community in South China, Chemosphere., 2014, 95, 363-369
14. Mayer P.*, Parkerton T.F., Adams R.G., Cargill J.G., Gan J., Gouin T., Gschwend P.M., Hawthorne S.B., Helm P., Witt G., You J., Escher B.I. Passive sampling methods for contaminated sediments: Scientific rationale supporting use of freely dissolved concentrations. Integrated Environmental Assessment and Management, 2014, 10, 197-209
15. Wang J., Ma H.-Z.*, Yuan W.-F., He W.-Y., Wang S.-S. You J. Synthesis and characterization of an inorganic/organic-modified bentonite and its application in methyl orange water treatment, Desalination and Water Treatment, 2014, 52, 7660–7672
16. Li Y.-L.^s, Du J.^s, Fang Z.-X., You J*. Dissipation of insecticidal Cry1Ac protein in different matrices and its toxicity to non-target aquatic organisms. Journal of Agricultural and Food Chemistry, 2013, 61, 10864-10871.
17. Zhang B.-Z.^p, Li H.-Z.^s, Wei Y.-L.^s, You J.* Bioaccumulation kinetics of polybrominated diphenyl ethers and decabromodiphenyl ethane from field-collected sediment to the oligochaete, Lumbriculus variegatus, Environmental Toxicology and Chemistry, 2013, 32, 2711-2718
18. Li H.-Z.^s, Sun B.-Q.^s, Chen X.^s, Lydy M.J., You J.* Addition of contaminant bioavailability and species susceptibility to a sediment toxicity assessment: Application in an urban stream in China, Environmental Pollution, 2013, 178, 135-141.
19. Li Y.-L.^s, Fang Z.-X., You J*. Application of Box-Behnken Experimental Design to optimize the extraction of insecticidal Cry1Ac from soil, Journal of Agricultural and Food Chemistry, 2013, 61, 1464-1470.
20. Du J.^s, Pang J.-X.^s, You J*. Bioavailability-based chronic toxicity measurements of permethrin to Chironomus dilutus. Environmental Toxicology and Chemistry, 2013, 32, 1403-1410
21. Li H.-Z.^s, Sun B.-Q.^s, Lydy M.J., You J*. Sediment-associated pesticides in an urban stream in Guangzhou, China: Implication of a shift in pesticide use patterns. Environmental Toxicology and Chemistry, 2013, 32, 1040-1047
22. Ding Y.-P., Landrum P.F., You J.*, Lydy M.J.* Assessing bioavailability and toxicity of permethrin and DDT in sediment using matrix solid phase microextraction. Ecotoxicology, 2013, 22, 109-117
23. Mackenbach E.M., You J., Mills M.A., Landrum P.F., Lydy M.J.* Application of a Tenax Model to Assess Bioavailability of PCBs in Field Sediments. Environmental Toxicology and Chemistry, 2012, 31, 2210-2216
24. Pang J.-X.^s, Sun B.-Q.^s, Li H.-Z.^s, Mehler W.T., You J*. Influence of bioturbation on bioavailability and toxicity of PAHs in sediment from an electronic waste recycling site in South China. Ecotoxicology and Environmental Safety, 2012, 84, 227-233
25. Ding Y., Landrum P.F., You J., Harwood A.D., Lydy M.J.* Use of solid phase microextraction to estimate toxicity. I. Relating fiber concentrations to toxicity. Environmental Toxicology and Chemistry, 2012, 31, 2159-2167
26. Ding Y., Landrum P.F., You J., Harwood A.D., Lydy M.J.* Use of solid phase microextraction to estimate toxicity. II. Relating fiber concentrations to body residues. Environmental Toxicology and Chemistry, 2012, 31, 2168-2174
27. Harwood A.D., Bunch A.R., Flickinger D.L., You J., Lydy M.J.* Predicting the toxicity of permethrin to Daphnia magna in water using SPME fibers. Archives of Environmental Contamination and Toxicology, 2012, 62, 438-444
28. Du J.^s, Mehler W.T., Lydy M.J., You J.* Toxicity of sediment-associated unresolved complex mixture and its impact on bioavailability of polycyclic aromatic hydrocarbons, Journal of Hazardous Materials, 2012, 203-204, 169-175
29. Wang J.-Z., Li H.-Z.^s, You J.* Distribution and toxicity of current-use insecticides in sediment of a lake receiving waters from areas in transition to urbanization, Environmental Pollution, 2012, 161, 128-133
30. Mehler W.T., Du J.^s, Lydy M.J., You J*. Joint toxicity of a pyrethroid insecticide, cypermethrin, and a heavy metal, lead, to the benthic invertebrate Chironomus dilutus. Environmental Toxicology and Chemistry, 2011, 30, 2838-2845
31. You J., Kelley R., Crouse C., Trushenski J.T., Lydy M.J.* Analysis of persistent halogenated hydrocarbons in fish feeds containing fish oil and other alternative lipid sources. Talanta, 2011, 85, 1291-1297
32. Bao L., You J., Zeng E.Y.* Sorption of polybrominated diphenyl ether (PBDEs) in low-density polyethylene film: Implication for bioavailability of BDE 209. Environmental Toxicology and Chemistry, 2011, 30, 1731-1738
33. Zhang B., Yu H., You J., Zeng E.Y.* Input pathways of organochlorine pesticides to typical freshwater cultured fish ponds of South China: Hints for pollution control. Environmental Toxicology and Chemistry, 2011, 30, 1272-1277
34. Zeng E.Y.*, You J., Cheng H. Balance between economic growth and environmental protection: Sustainability through better science. Journal of Environmental Monitoring, 2011, 13, 787–788
35. You J.*, Harwood A.D., Li H.-Z^s, Lydy M.J. Chemical techniques for assessing bioavailability of sediment- associated contaminants: SPME versus Tenax extraction. Journal of Environmental Monitoring, 2011, 13, 792-800
36. Li H.-Z.^s, Bai J.-M., Li Y.-T., Cheng H.-F., Zeng E.Y., You J.* Short-range transport of contaminants released from e-waste recycling site in South China. Journal of Environmental Monitoring, 2011, 13, 836-843
37. Mehler W.T., Li H.-Z.^s, Lydy M.J., You J.* Identifying the causes of sediment-associated toxicity in urban waterways of the Pearl River Delta, China. Environmental Science and Technology, 2011, 45, 1812-1819
38. Li H.-Z.^s, Mehler W.T., Lydy M.J., You J.* Occurrence and distribution of sediment-associated insecticides in urban waterways in the Pearl River Delta, China. Chemosphere, 2011, 82, 1373–1379
39. Ding Y., Weston D.P., You J.*, Rothert A.K., Lydy M.J. Toxicity of sediment-associated pesticides to Chironomus dilutus and Hyalella azteca. Archives of Environmental Contamination and Toxicology, 2011, 61, 83-92
40. Mehler W.T., Li H.-Z.^s, Pang J.-X.^s, Sun B.-Q^s, Lydy M.J., You J.* Bioavailability of hydrophobic organic contaminants in sediment with different particle size distributions. Archives of Environmental Contamination and Toxicology, 2011, 61, 74-82
41. Yan Y., Yang Y., You J.*, Yang G., Xu Y., Huang N., Wang X., Ran D., Yuan X., Jin Y., Fan Y., Lei J., Li W., Gu H.* Permethrin modulates cholinergic mini-synaptic currents by partially blocking the calcium channel. Toxicology Letters, 2011, 201, 258-263
42. You J.*, Li H.-Z., Lydy M.J.* Assessment of sediment toxicity with SPME-based approaches. In Comprehensive Analytical Chemistry, Volume 67, Eddy Y. Zeng Ed., Elsevier, 2015, pp. 161-194.
43. Lydy M.J.*, Belden J.B., You J., Harwood A.D. Toxicological significance of pesticide residues in aquatic animals. In: Environmental contaminants in biota: Interpreting tissue concentrations, Beyer W.N., Meador J., Eds., CRC Press, Taylor & Francis Group, 2011, pp. 403-406

* Corresponding author.
^s Graduate student
^p Post-doctoral fellow

科研活动

科研项目 （1） 被动采样在珠三角典型城市水体沉积物毒性评价中的应用：常见农药，主持，国家级，2015-01--2018-12
（2） 珠江广州段水体沉积物生态毒性的鉴别与评价，主持，国家级，2013-01--2016-12
（3） 环境地球化学，主持，国家级，2013-01--2015-12
（4） 沉积物中疏水性农药与重金属复合毒性效应的研究，主持，部委级，2012-11--2014-10
（5） 典型污染物的毒性测试与评价技术研究，参与，国家级，2012-01--2015-12
（6） 有机污染物的区域环境地球化学过程，参与，国家级，2012-01--2014-12

指导学生已指导学生

庞俊晓 博士研究生 083001-环境科学

林志惠 硕士研究生 077501-环境科学

杜娟 博士研究生 083001-环境科学

李衍亮 博士研究生 083001-环境科学

李慧珍 博士研究生 083001-环境科学

祁红学 博士研究生 083001-环境科学

现指导学生

陈鑫 博士研究生 083001-环境科学

易小意 博士研究生 083001-环境科学

程飞 硕士研究生 070902-地球化学

熊晶晶 博士研究生 083001-环境科学

裴媛媛 博士研究生 083001-环境科学

廉秀峰 硕士研究生 077601-环境科学

徐步青 硕士研究生 070902-地球化学

马萍 博士研究生 083001-环境科学

王顺慧 博士研究生 083001-环境科学

工作经历2002-2007年 美国南伊利诺伊州立大学化学系和动物系任博士后研究人员、
助理科学家、副科学家、研究顾问和兼职研究生导师（至今），
从事液相色谱检测器研制以及水生毒理与毒代动力学研究。
2007-2009年 美国中密苏里州立大学化学系任助理教授，从事有机污染物环境
行为和生物有效性研究。
2009年至今 中国科学院广州地球化学研究所，从事水体沉积物中毒性污染物的
生物有效性和生态风险评价研究。
招生信息

招生专业 环境科学



招生方向 环境化学，水生毒理学，沉积物风险评估


工作经历

工作简历 2009-01--今 中科院广州地球化学研究所 研究员
2007-08--2009-01 美国中密苏里大学 Tenure-track 助理教授
2006-03--今 美国南伊利诺伊大学动物系 兼职研究生导师
2006-01--2006-06 美国南伊利诺伊大学化学系 兼职研究顾问
2002-07--2007-08 美国南伊利诺伊大学动物系及渔业中心 博士后与助理科学家
2002-01--2002-12 美国南伊利诺伊大学化学系 副科学家


社会兼职
奖励信息2014年，获中国科学院优秀导师奖
2014年，获广州教育基地优秀研究生导师
2013年，获中国科学院大学-BHPB导师科研奖
2011年，国际环境毒理与化学协会（SETAC）与英国皇家化学协会（RSC）
“SETAC/RSC奖”
2010年，中国科学院广州分院、广东省科学院“优秀青年科技工作者”