基本信息
于波 男 硕导 微生物研究所
电子邮件:yub@im.ac.cn
联系电话: **
手机号码:
通信地址: 中关村北二条 中国科学院微生物研究所北楼507
邮政编码: 100190
研究领域针对生物基化学品开发相关合成生物技术体系,侧重于乳酸等三碳生物基材料与化学品的微生物法生产:
1. 乳酸等三碳生物基化学品的微生物合成技术与产业化开发
2. 具有工业应用潜力的极端酶与菌株的筛选、改造与应用
3. 芳香杂环类化合物的微生物转化
招生信息工业微生物的耐受机制与工程改造
招生专业微生物学、分子生物学、发酵工程
招生方向
教育背景1997-2001 山东大学,生物技术专业,学士
2001-2006 山东大学,资源与环境微生物学专业,博士
出国学习工作2008-2010 德国Helmholtz Centre for Infection Research 博士后
德国Hamburg University of Technology 博士后
工作经历2006-2008 中国科学院微生物研究所,助理研究员
2010- 中国科学院微生物研究所,副研究员、青年研究组长
专利与奖励
专利成果授权专利:
1.一种生产D-乳酸的方法及其专用芽孢乳杆菌。授权专利号: **6.2
2.一种生产L-乳酸的方法及其专用凝结芽孢杆菌。授权专利号: **0.9
3.一株红平红球菌及其在原油脱硫中的应用。授权专利号:**9.X
4.一株基因重组的红平红球菌及其在脱除原油有害物--硫和氮中的应用。授权专利号:**9.8
5.一株可耐受有机溶剂的恶臭假单胞菌及其在双液相反应中的应用。授权专利号:**0.1
科研活动
科研项目在研项目:
973计划项目“人工合成细胞工厂”(2011-2015),子课题负责人
863计划重大项目“新一代聚乳酸的生物—化学组合合成技术”(2011-2015),子课题负责人
中国科学院知识创新工程方向项目“高浓度和高光学纯D-乳酸生物制造的核心技术研究” (2011-2013),负责人
中国科学院微生物研究所科技成果转化基金项目“高浓度、高光学纯D-乳酸生物制造的产业化开发”(2011-2012),负责人
已完成项目:
国家自然科学基金“原油中硫、氮杂环类环境污染物的微生物同时脱除研究”(2008-2010),负责人
指导学生管祥辰 2011- (工程硕士)
代表性论文1. Yu B, Sun JB, Bommareddy RR, Song LF, Zeng AP. Novel (2R,3R)-2,3- butanediol dehydrogenase from potential industrial strain Paenibacillus polymyxa ATCC 12321. Appl. Environ. Microbiol. 2011, 77: 4230-4233.
2. Wang LM, Zhao B, Liu B, Yu B, Ma CQ, Su F, Hua DL, Li QG, Ma YH, Xu P. Efficient production of l-lactic acid from corncob molasses, a waste by-product in xylitol production, by a newly isolated xylose utilizing Bacillus sp. strain. Biores. Technol. 2010, 101: 7908-7915.
3. Wang LM, Zhao B, Liu B, Yang CY, Yu B, Li QG, Ma CQ, Xu P, Ma YH. Efficient production of l-lactic acid from cassava powder by Lactobacillus rhamnosus. Biores. Technol. 2010, 101: 7895-7901.
4. Qin JY, Zhao B, Wang XW, Wang LM, Yu B, Ma YH, Ma CQ, Tang HZ, Sun JB, Xu P. Production of L-lactic acid by a newly isolated thermophilic strain Bacillus sp. 2-6. PLoS ONE 2009, 4(2): e4359.
5. Li JC, Feng JH, Li Q, Ma CQ, Yu B, Gao C, Xu P. Both FMNH2 and FADH2 can be utilized by the dibenzothiophene monooxygenase from a desulfurizing bacterium Mycobacterium goodii X7B. Biores. Technol. 2009, 100: 2594-2599.
6. Xu P, Feng JH, Yu B, Li FL, Ma CQ. Recent developments of biodesulfurization of fossil fuels. Adv Biochem Engin/Biotechnol, 2009, 113: 255-274.
7. Gai ZH#, Yu B#, Wang XY, Deng ZX, Xu P. Microbial transformation of benzothiophenes, with carbazole as the auxiliary substrate, by Sphingomonas sp. strain XLDN2-5. Microbiology-SGM, 2008, 154: 3804-3812 (#Equal contributors) .
8. Xu P, Gai ZH, Yu B, Ma CQ. Microbial degradation of carbazole and dibenzofuran by genus Sphingomonas: perspective and challenge. (2008) In Shuang-jiang Liu and Harold L. Drake eds. Microbes and the Environment: Perspectives and Challenges (Chapter 13): 89-96, Science Press, Beijing, China.
9. Gai ZH#, Yu B#, Li L, Wang Y, Ma CQ, Feng JH, Deng ZX, Xu P. Cometabolic degradation of dibenzofuran and dibenzothiophene by a newly isolated carbazole-degrading Sphingomonas sp. strain. Appl. Environ. Microbiol. 2007, 73: 2832-2838 (#Equal contributors) .
10. Wang X, Gai ZH, Yu B, Feng JH, Xu CY, Yuan Y, Li ZX, Xu P. Degradation of carbazole by microbial cells immobilized in magnetic gellan gum gel beads. Appl. Environ. Microbiol. 2007, 73: 6421-6428.
11. Hua DL, Ma CQ, Lin S, Song LF, Deng ZX, Maomy Z, Zhang ZB, Yu B, Xu P. Biotransformation of isoeugenol to vanillin by a newly isolated Bacillus pumilus strain: identification of major metabolites. J. Biotechnol. 2007, 130: 463-470.
12. Xu P*, Yu B*, Li FL, Cai XF, Ma CQ. Microbial degradation of sulfur, nitrogen and oxygen heterocycles. Trends Microbiol. 2006, 14: 398-405. (*Corresponding authors)
13. Yu B, Ma CQ, Zhou WJ, Zhu SS, Wang Y, Qu JY, Li FL, Xu P. Simultaneous biodetoxification of S, N and O pollutants by engineering a carbazole-degrading gene cassette in a recombinant biocatalyst. Appl. Environ. Microbiol. 2006, 72: 7373–7376.
14. Tao F#, Yu B#, Xu P, Ma CQ. Biodesulfurization in biphasic systems containing organic solvents. Appl. Environ. Microbiol. 2006, 72: 4604-4609. (#Equal contributors)
15. Yu B, Xu P, Zhu SS, Cai XF, Wang Y, Li L, Li FL, Liu XY, Ma CQ. Selective biodegradation of S and N heterocycles by a recombinant Rhodococcus erythropolis strain containing carbazole dioxygenase. Appl. Environ. Microbiol. 2006, 72: 2235-2238.
16. Yu B, Xu P, Shi Q, Ma CQ. Deep desulfurization of diesel oil and crude oils by a newly isolated Rhodococcus erythropolis strain. Appl. Environ. Microbiol. 2006, 72: 54-58.
17. Yu B, Ma CQ, Zhou WJ, Wang Y, Cai XF, Tao F, Zhang Q, Tong MY, Qu JY, Xu P. Microbial desulfurization of gasoline by free whole-cells of Rhodococcus erythropolis XP. FEMS Microbiol. Lett. 2006, 258: 284-289.
18. Feng JH, Zeng YY, Ma CQ, Cai XF, Zhang Q, Tong MY, Yu B, Xu P. Surfactant Tween 80 enhances biodesulfurization. Appl. Environ. Microbiol. 2006, 72: 7390–7393.
19. Li L, Li QG, Li FL, Shi Q, Yu B, Liu FR, Xu P. Degradation of carbazole and its derivatives by a Pseudomonas sp. Appl. Microbiol. Biotechnol. 2006, 73: 941-948.
20. Yu B, Huang J, Cai XF, Liu XY, Ma CQ, Li FL, Xu P. A novel method for conversion of valuable BDS intermediates HPBS/Cx-HPBS from DBT/Cx-DBT. Chinese Chem. Lett. 2005, 16: 935-938.
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