姓名：郑焱 性别：女 职称：副教授 招生院所：基础医学院 招生类型：科学学位(硕) 招生专业：生理学(硕) 研究方向名称：阿尔茨海默病相关认知环路的功能研究 电子信箱：zhengyan@ccmu.edu.cn


社会任职
1. 中国生理学会青年工作委员会委员
2. 北京医学会神经病学分会第十届委员会痴呆与认知障碍学组委员
3. 中国老年学和老年医学学会脑认知与健康分会委员
个人简历
1. 200009-200307:吉林大学白求恩医学部和北京大学医学部 硕士研究生
2. 200509-200807:首都医科大学 博士研究生
3. 200808-201805:首都医科大学 教师
4. 201409-201508:美国纽约州立大学布法罗分校 生理学与生物物理学系 访问
重要学术论文
1. Li N, Li Y, Li LJ, Zhu K, Zheng Y*, Wang XM*..Glutamate receptor delocalization in postsynaptic membrane and reduced hippocampal synaptic plasticity in the early stage of Alzheimer's disease.. Neural Regen Res.. 2019,14(6):1037-1045.SCI
2. Zheng Y#, Liu A#, Wang ZJ#, Cao Q, Wang W, Lin L, Ma K, Zhang F, Wei J, Matas E, Cheng J, Chen GJ, Wang X, Yan Z*..Inhibition of EHMT1/2 rescues synaptic and cognitive functions for Alzheimer's disease.. Brain. 2019,142(3):787-807.SCI
3. Su RJ, Zhen JL, Wang W, Zhang JL, Zheng Y*, Wang XM*.Time-course behavioral features are correlated with Parkinson's disease associated pathology in a 6-hydroxydopamine hemiparkinsonian rat model.. Mol Med Rep.. 2018,17(2):3356-3363.SCI
4. Zhao J, Yu S, Zheng Y, Yang H, Zhang J..Oxidative Modification and Its Implications for the Neurodegeneration of Parkinson's Disease.. Mol Neurobiol.. 2017,5(2):1404.SCI
5. Su R, Sun M, Wang W, Zhang J, Zhang L, Zhen J, Qian Y, Zheng Y*, Wang X*.A Novel Immunosuppressor, (5R)-5-Hydroxytriptolide, Alleviates Movement Disorder and Neuroinflammation in a 6-OHDA Hemiparkinsonian Rat Model.. Aging Dis.. 2017,8(1):31-43.SCI
6. Junli Zhen, Yanjing Qian, Jian Fu, Ruijun Su, Haiting An, Wei Wang, Yan Zheng*, Xiaomin Wang*.Deep Brain Magnetic Stimulation Promotes Neurogenesis and Restores Cholinergic Activity in a Transgenic Mouse Model of Alzheimer’s Disease.. Front. Neural Circuits. 2017,11:48.SCI
7. Junli Zhen, Yanjing Qian, Xiechuan Weng, Wenting Su, Jianliang Zhang, Lihui Cai, Lin Dong, Haiting An, Ruijun Su, Jiang Wang, Yan Zheng*, Xiaomin Wang*.Gamma Rhythm Low Field Magnetic Stimulation Alleviates Neuropathological Changes and Rescues Memory and Cognitive Impairments in a Mouse Model of Alzheimer's Disease. . Alzheimers Dement (N Y). 2017,3(4):487-497.
8. Qu J, Yu S, Zheng Y, Zheng Y, Yang H, Zhang J*.Aptamer and its applications in neurodegenerative diseases.. Cell Mol Life Sci.. 2017,74(4):1-13.SCI
9. Yan-Qiu Cui#, Qi Wang#, Jun-Ya Wang, Dong-Mei Zhang, Gui-Lian Tan, Bing Xiao, Yan Zheng*, Xiao-Min Wang*.Triptolide prevents memory deficits and amyloid-β aggregation accompanied by inhibition of inflammation and MAPKs activity in APP/PS1 mice. Curr Alzheimer Res. 2016,13(3):288-296.SCI
10. Dong L, Li YZ, An HT, Wang YL, Chen SH, Qian YJ, Wang K, Zhen JL, Fan Z, Gong XL, Zheng Y, Wang XM*..The E3 Ubiquitin Ligase c-Cbl Inhibits Microglia-Mediated CNS Inflammation by Regulating PI3K/Akt/NF-κB Pathway.. CNS Neurosci Ther.. 2016,22(8):661-9.SCI
11. Zhao J, Zheng Y, Xue F, Chang Y, Yang H, Zhang J*..Molecular basis of reactive oxygen species-induced inactivation of α4β2 nicotinic acetylcholine receptors. . Free Radic Biol Med. . 2016,97:520-30.SCI
12. Yan H, Pan N, Xue F, Zheng Y, Li C, Chang Y, Xu Z, Yang H, Zhang J*.The coupling interface and pore domain codetermine the single-channel activity of the α7 nicotinic receptor. . Neuropharmacology. 2015,95:448-458.SCI
13. Wang Q#, Xiao B#, Cui S, Song H, Qian Y, Dong L, An H, Cui Y, Zhang W, He Y, Zhang J, Yang J, Zhang F, Hu G, Gong X, Yan Z, Zheng Y*, Wang X*.Triptolide treatment reduces Alzheimer's disease (AD)-like pathology through inhibition of BACE1 in a transgenic mouse model of AD. Dis Model Mech. 2014,7(12):1385-95.SCI
14. Ji R, Tian S, Lu HJ, Lu Q, Zheng Y, Wang X, Ding J, Li Q, Lu Q*.TAM receptors affect adult brain neurogenesis by negative regulation of microglial cell activation.. J Immunol. 2013,191(12):6165-77.SCI
主编或副主编的著作/译著
重要奖项