姓名：王雯 性别：女 职称：教授 招生院所：基础医学院 招生类型：科学学位(博) 科学学位(硕) 招生专业：病理学与病理生理学(博) 病理学与病理生理学(硕) 研究方向名称：衰老相关心血管疾病研究 电子信箱：wangwen@ccmu.edu.cn


社会任职
1. 《中南医学科学杂志》编委
2. 北京生理科学会第十二届理事会理事
3. 北京生理科学会第一届血管医学专业委员会血管衰老学组组长
个人简历
1. 200009-200512:首都医科大学 讲师
2. 200109-200407:中国协和医科大学 博士研究生
3. 200601-201412:首都医科大学 副教授
4. 200709-200808:美国纽约州布法罗大学 访问
5. 201501-:首都医科大学 教授
重要学术论文
1. Shangyue Zhang,Yuerong Zhang, Xinyu Zhang, Chenghua Luo, Yan Cao, Dengyu Ji, Wenjing Yan, Ke Xue, Jiayin Chai, Hongyan Dai*, Wen Wang*.Nitrative stress related autophagic insufficiency participates in hyperhomocysteinemia induced renal aging. Oxidative Medicine and Cellular Longevity. 2020,2020:**.SCI
2. Yu Dong, Yan Bai, Shangyue Zhang, Wenli Xu, Jiahui Xu, Yi Zhou, Suli Zhang, Ye Wu, Haicun Yu, Ning Cao, Huirong Liu* ,Wen Wang*.Cyclic peptide RD808 reduces myocardial injuryinduced by β1-adrenoreceptor autoantibodies. Heart and Vessels. 2019,34(6):1040-1051 .SCI
3. Xu J#, Jiao K#, Liu X, Sun Q, Wang K, Xu H, Zhang S, Wu Y, Wu L, Liu D, Wang W*, Liu H*.Omi/HtrA2 Participates in Age-Related Autophagic Deficiency in Rat Liver. Aging Dis. 2018,9(6):1031-1042.SCI
4. Wang H , Zhou Y, Guo Z , Dong Y , Xu J , Huang H, Liu H , Wang W*.Sitagliptin Attenuates Endothelial Dysfunction of Zucker Diabetic Fatty Rats: Implication of the Anti-peroxynitrite and Autophagy. J Cardiovasc Pharm T. 2018,23（1）:66-78.SCI
5. Ning Cao, Hao Chen, Yan Bai, Xiaochun Yang, Wenli Xu, Weiwei Hao, Yi Zhou, Jiayin Chai, Ye Wu, Zhaojia Wang, Xiaochen Yin, Li Wang, Wen Wang*, Huirong Liu*,Michael L.X..β2-adrenergic receptor autoantibodies alleviate myocardial damage induced by β1-adrenergic receptor autoantibodies in heart failure. Cardiovascular Research. 2018,114(11):1487-1498.SCI
6. Yi Zhou#, Zhiying Guo#, Wenjing Yan, Wen Wang*.Cardiovascular effects of sitagliptin ——an anti-diabetes medicine. Clinical and Experimental Pharmocology and Physiology. 2018,45:628-635.SCI
7. Yi Zhou, Huanyuan Wang, ,Fuli Man, Zhiying Guo, Jiahui Xu, Wenjing Yan, Jiaying Li, Qi Pan*, Wen Wang*.Sitagliptin protects cardiac function by reducing nitroxidative stress and promoting autophagy in Zucker Diabetic Fatty (ZDF) rats. Cardiovascular Drugs and Therapy. 2018,32(6):541-552.SCI
8. Huanyuan Wang, Qi Sun, Yi Zhou, Hui Zhang, Chenghua Luo, Jiahui Xu, Yu Dong, Ye Wu, Huirong Liu, Wen Wang*.Nitration-mediated deficiency of cystathionine β-synthase activity accelerates the progression of hyperhomocysteinemia. Free Radical Biology and Medicine. 2017,113:519-529.SCI
9. Dong Y, Sun Q, Liu T, Wang H, Jiao K, Xu J, Liu X，Liu H，Wang W*.Nitrative Stress Participates in Endothelial Progenitor Cells Injury in Hyperhomocysteinemia. PLoS ONE. 2016,11(7):e**.SCI
10. Sun Q，Dong Y，Wang H， Jiao K， Xu J， Ma L， Huang H， Liu H， Wang W*.Anti-peroxynitrite treatment ameliorates vasorelaxation of resistance arteries in aging rats: involvement with protection of circulating endothelial progenitor cells. J Cardiovasc Pharm. 2016,68(5):334-341.SCI
11. Zhang H , Sun Q, Liu T, Ma L, Zhen P, Wang K, Lu L, Liu X, Zhang X, Song D, Zuo X，Liu H，Wang W*.Alleviation of Plasma Homocysteine Level by Phytoestrogen α--Zearalanol Might Be Related to the Reduction of Cystathionine β-Synthase Nitration. Biomed Res Int. 2014,2014:143192.SCI
12. Liu T, Hou DD, Zhao Q, Liu W, Zhen PP, Xu JP, Wang K, Huang HX, Li X, Zhang H, Xu HB, Wang W*.Phytoestrogen α-zearalanol attenuates homocysteine-induced apoptosis in human umbilical vein endothelial cells. Biomed Res Int. 2013,2013:813450.SCI
13. Zhao Q，Xu XL，Xiong HY，Huang W，Zhang M， Wang Y，Wang SY，Wang W*.Endothelial injury by exenatide might be related to the reduction of nitrooxidative stress. Biomed Res Int. 2013,2013:843657.SCI
14. Zhen PP, Zhao Q,Hou DD, Liu T, Jiang DJ, Duan JH, Lu LQ, Wang W*.Genistein attenuates vascular endothelial impairment in ovariectomized hyperhomocysteinemic rats . J Biomed Biotechnol. 2012,2012:730462.SCI
15. Zhen P, Duan J, Zhao Q, Hou D, Wang H, Hong N , Zhen H, Wang W* .Phytoestrogen α-zearalanol improves vascular function in ovariectomized hyperhomocysteinemic rats. Atherosclerosis. 2011,215（2）:309-315.SCI
16. Wang W，Lang JK, Suzuki G, Canty JM Jr, Cimato T*.Statins enhance clonal growth of late outgrowth endothelial progenitors and increase myocardial capillary density in the chronically ischemic heart. PLoS One. 2011,6(9):e24868.SCI
17. Xu H, Duan J, Wang W, Dai S, Wu Y, Sun R, Ren J.Reactive oxygen species mediate oxidized low-density lipoprotein-induced endothelin-1 gene expression via extracellular signal-regulated kinase in vascular endothelial cells. J Hypertens. 2008,26(5):956-963.SCI
18. Liu W, Zhu ZQ, Wang W, Zu SY, Zhu GJ*..Crucial roles of GATA-2 and SP-1 in adrenomedullin-affected expression of tissue factor pathway inhibitor in human umbilical vein endothelial cells exposed to lipopolysaccharide.. Thromb Haemost. 2007,97(5):839-846.SCI
19. Liu W, Xu CL, Zhu ZQ, Wang W, Han SM, Zu SY, Zhu GJ*.Characteristics of calcaneus quantitative ultrasound normative data in Chinese mainland men and women. Osteoporos Int. 2006,17(8):1216-1624.SCI
20. Wang W, Zhu GJ*, Zu SY.Effects of 17β-Estradiol and Phytoestrogen α-Zearalanol on Tissue Factor in Ovariectomized Rats and Endothelial Cells. Chinese J Physiol. 2004,47（2）:67-72 .SCI
21.
主编或副主编的著作/译著
1. 《病理生理学》,副主编,人民卫生出版社,201904
2. 《病理学与病理生理学学习指导》,主编,人民卫生出版社,201709
3. 《病理学与病理生理学》,副主编,人民卫生出版社,201706
4. 《医学生理学》,副主编,首都医科大学内部出版,201612
5. 《病理生理学》,副主编,北京大学医学出版社,201506
6. 《病理生理学复习纲要与题解》,主编,清华大学出版社,200705
7. 《病理生理学概论》,副主编,首都医科大学内部出版,200506
重要奖项
1. 抗G蛋白偶联受体自身抗体在心血管疾病中的作用及相关机制探究 华夏医学科技奖 二等奖 201912
2. 首都医科大学优秀教师奖 201309
3. 霍英东教育基金会第十一届高等院校青年教师奖（自然科学） 三等奖 200812