姓名：朱海梅 性别：女 职称：副教授 招生院所：药学院 招生类型：科学学位(硕) 招生专业：药物化学(硕) 研究方向名称：生物大分子模拟，药物设计、合成和评价 电子信箱：hmzhu@ccmu.edu.cn


社会任职
个人简历
1. 199709-200107:南京师范大学 学士
2. 200109-200407:北京工业大学 硕士
3. 200408-200908:美国休斯敦大学 博士
4. 200909-201005:美国休斯敦大学 博士后
5. 201012-201312:首都医科大学 讲师
6. 201401-202112:首都医科大学 副教授
重要学术论文
1. Zhu, H.; Wang, Y.; Song, C.; Feng, Q.; Wu, J.; Zhao, S.; Gui, L.; Zhang, X.; Zhao, M.*; Peng, S.*.Docking of THPDTPI: to explore P-selectin been a common target of anti-tumor, anti-thrombotic and anti-inflammatory agent. Oncotarget. 2018,9:268-281.SCI
2. Wu, J.#; Zhu, H.#; Yang, G.; He, J.; Wang, Y.; Zhao, S.; Zhang, X.; Gui, L.; Zhao, M.*; Peng, S.*.Design and synthesis of nano-scaled IQCA-TAVV as a delivery capable of anti-platelet activation, targeting arterial thrombus and releasing IQCA. International Journal of Nanomedicine. 2018,13:1139-1158.SCI
3. Wu, J. H.#; Zhu, H. M.#; Zhao, M.*; Wang, Y. J.; Yang, G. D.; Wang, Y. N.; Zhao, S. R.; Gui, L.; Zhang, X. Y.; Peng, S. Q*..IQCA-TASS: a nano-scaled P-selectin inhibitor capable of targeting thrombus and releasing IQCA/TARGD(S)S in vivo. J Mater Chem B. 2017,5:917-927.SCI
4. Wu, J. H.; Zhao, M.*; Wang, Y. J.; Wang, Y. N.; Zhu, H. M.; Zhao, S. R.; Gui, L.; Zhang, X. Y.; Peng, S. Q*..N-(3-hydroxymethyl-β-carboline-1-yl-ethyl-2-yl)-l-Phe: development toward a nanoscaled antitumor drug capable of treating complicated thrombosis and inflammation. Drug Design, Development and Therapy. 2017,11:225-239.SCI
5. Zhu, H. M.#; Song, Y. B.#; Wang, Y. J.; Zhao, M.*; Ren, Y.; Wang, Y. N.; Zhao, S. R.; Wu, J. H.; Peng, S. Q.*.Design, synthesis and evaluation of a novel pi-pi stacking nano-intercalator as an anti-tumor agent. Medchemcomm. 2016,7(2):247-257.SCI
6. Xu, W. Y.; Zhao, M.*; Wang, Y. J.; Zhu, H. M.; Wang, Y. N.; Zhao, S. R.; Wu, J. H.; Peng, S. Q.*.Design, synthesis, and in vivo evaluations of benzyl N-omega-nitro-N-alpha-(9H-pyrido[3,4-b]indole-3-carbonyl)- L-argininate as an apoptosis inducer capable of decreasing the serum concentration of P-selectin. Medchemcomm. 2016,7(9):1730-1737.SCI
7. Wu, J.; Zhao, M.*; Wang, Y.; Wang, Y.; Zhu, H.; Zhao, S.; Peng, S.*.A novel lead of P-selectin inhibitor: Discovery, synthesis, bioassays and action mechanism. Bioorg Med Chem Lett. 2016,26(19):4631-4636.SCI
8. Jiang, X. Y.; Zhao, M.*; Wang, Y. J.; Zhu, H. M.; Zhao, S. R.; Wu, J. H.; Song, Y. B.; Peng, S. Q.*.RGD(F/S/V)-Dex: towards the development of novel, effective, and safe glucocorticoids. Drug Des Dev Ther. 2016,10:1059-1076.SCI
9. Feng, Q. Q.; Zhao, M.*; Gan, T. P.; Zhu, H. M.; Wang, Y. N.; Zhao, S. R.; Wang, Y. J.; Wu, J. H.; Peng, S. Q.*.DHDMIQK(KAP): a novel nano-delivery system of dihydroxyl-tetrahydro-isoquinoline-3-carboxylic acid and KPAK towards the thrombus. J. Mater. Chem. B. 2016,4(36):5991-6003.SCI
10. Jin, S.#; Wang, Y.#; Zhu, H.; Wang, Y.; Zhao, S.; Zhao, M.*; Liu, J.; Wu, J.; Gao, W.; Peng, S.*.Nanosized aspirin-Arg-Gly-Asp-Val: delivery of aspirin to thrombus by the target carrier Arg-Gly-Asp-Val tetrapeptide. ACS Nano. 2013,7(9):7664-7673.SCI
11. Zhu, H. M.; Wang, Y. J.; Zhao, M.*; Wu, J. H.; Zhang, X. Y.; Yang, G. D.; Peng, S. Q.*.Energy minimized crystal structures of P-selectins based on molecular dynamics simulation: Leading to two average structures capable of designing anti-thrombotic agents. MedChemComm. 2013,4:1066-1072.SCI
12. Zhu, H. M.; Wang, Y. J.; Wang, Y. A.; Zhao, S. R.; Zhao, M.*; Gui, L.; Xu, W. Y.; Chen, X. A.; Wang, Y. M.*; Peng, S. Q.*.Folded conformation, cyclic pentamer, nano-structure and PAD4 binding mode of YW3-56. J Phys Chem C. 2013,117:10070-10078.SCI
主编或副主编的著作/译著
重要奖项
1. 第八届北京市大学生化学实验竞赛一等奖指导教师 第八届北京市大学生化学实验竞赛一等奖指导教师 省级 201612
2. 首都医科大学第六届青年教师基本功比赛英文授课比赛决赛一等奖及最佳教案奖 首都医科大学第六届青年教师基本功比赛英文授课比赛决赛一等奖及最佳教案奖 校级 201312
3. 首都医科大学优秀教师奖 首都医科大学优秀教师奖 校级 201312
4. 第四届北京市大学生化学实验竞赛二等奖指导教师 第四届北京市大学生化学实验竞赛二等奖指导教师 省级 201122
5. 美国南得克萨斯大学夏季学士培训优秀导师奖 美国南得克萨斯大学夏季学士培训优秀导师奖 校级 200908