姓名：华琳 性别：女 职称：副教授 招生院所：生物医学工程学院 招生类型：科学学位(硕) 招生专业：生物医学工程(硕) 研究方向名称：生物统计与生物信息学 电子信箱：hualin7750@139.com


社会任职
1. 中华临床医药卫生杂志编委
2. Plos one杂志审稿人
3. Coronary Artery Disease杂志审稿人
4. 北京医学会健康管理学分会第三届委员会质量控制与改进学组委员
5. 北京市体检质量控制和改进中心专家委员会委员
个人简历
1. 199209-199607:首都师范大学数学系 学习
2. 200109-200404:北京邮电大学理学院 硕士研究生学习
3. 200404-:首都医科大学生物医学工程学院 任职
4. 200709-201007:首都医科大学生物医学工程学院 博士研究生学习
5. 201109-201207:北京大学分子医学研究所人类群体遗传学研究室 研修
重要学术论文
1. Wenbin Xu, Lin Hua*, Hong Xia*.Integrative analysis of mRNA, miRNA and lncRNA profiles reveals the commonness between bladder cancer and breast cancer. Translational Cancer Research. 2020,1:1-21.SCI
2. T.-T. Shi, Z. Xin*, L. Hua*, R.-X. Zhao, Y.-L. Yang, H. Wang, S. Zhang, W. Liu, R.-R. Xie.Alterations in the intestinal microbiota of patients with severe and active Graves’ orbitopathy: a cross-sectional study. Journal of Endocrinological Investigation. 2019,1:1-12.SCI
3. Zhong Xin*, Lin Hua *,Yi-Lin Yang, Ting-Ting Shi,Wei Liu, Xiu Tuo, Yu Li, Xi Cao, Fang-Yuan Yang.A Pathway Analysis Based on Genome-Wide DNA Methylation of Chinese Patients with Graves’ Orbitopathy. BioMed Research International. 2019,Article ID **:1-10.SCI
4. Ting-Ting Shi#,Lin Hua#,Hua Wang, Zhong Xin*.The Potential Link between Gut Microbiota and Serum TRAb in Chinese Patients with Severe and Active Graves’ Orbitopathy. International Journal of Endocrinology. 2019,2019, Article ID **:1-12.SCI
5. Ting-Ting Shi#,Lin Hua#, Zhong Xin,Yu Li,Wei Liu,Yi-Lin Yang.Identifying and Validating Genes with DNA Methylation Data in the Context of Biological Network for Chinese Patients with Graves’ Orbitopathy. International Journal of Endocrinology. 2019,Volume 2019, Article ID **:1-9.SCI
6. 徐文彬，郑卫英，夏翃，华琳*.肌层浸润性膀胱癌亚型的生物信息学分析. 北京生物医学工程. 2018,37(1):51-56.核心期刊
7. Wenbin Xu,Hong Xia, Wei Liu, Weiying Zheng,Lin Hua*.Exploration of genetics commonness between bladder cancer and breast cancer based on a silcio analysis on disease subtypes. Technology and Health Care. 2018,26:S361–S377.SCI
8. Jin Hao#,*,Lin Hua#,Xinxing Fu,Xuelian Zhang,Qijuan Zou,Yongxin Li.Genome-wide DNA methylation analysis of human peripheral blood reveals susceptibility loci of diabetes-related hearing loss. Journal of Human Genetics. 2018,9:1-10.SCI
9. Lin Hua*,#, Hong Xia#, Wei-ying Zheng, Li An.Gene Regulation Network Based Analysis Associated with TGF-beta . Iranian J Biotech. 2017,15(1):e1308.SCI
10. Z. Xin#,*,L. Hua#, T.‑T. Shi,X. Tuo,F.‑Y. Yang, Y. Li,X. Cao, J.‑K. Yang*.A genome‑wide DNA methylation analysis in peripheral blood from patients identifies risk loci associated with Graves’ orbitopathy. journal of endocrinological investigation. 2017,11:1-11.SCI
11. W. -Y. Zheng, W. -X. Zheng, L. Hua*.Detecting Shared Pathways Linked to Rheumatoid Arthritis with Other Autoimmune Diseases in a in silico Analysis. Molecular Biology. 2016,50(3):462–469.SCI
12. L. An, H. Xia, P. Zhou, L. Hua*.Exploration of association between EPHX1 and chronic obstructive pulmonary disease on the basis of combined data mining. Genetics and Molecular Research. 2016,15(2):1-12.SCI
13. Li An, Yingxiang Lin, Ting Yang, Lin Hua* .Exploring the interaction among EPHX1, GSTP1, SERPINE2, and TGFB1 contributing to the quantitative traits of chronic obstructive pulmonary disease in Chinese Han population. Human Genomics. 2016,10(13):1-12.SCI
14. Lin Hua, Weiying Zheng, Hong Xia, Ping Zhou, Li An.Integration of multi-microarray datasets to identify chronic obstructive pulmonary disease-related miRNAs. Bio-Medical Materials and Engineering. 2015,26:S1903–S1915.SCI
15. Dongguo Li,Hong Xia, Zhen-ya Li,Lin Hua*,Lin Li*.Identification of Novel Breast Cancer Subtype-Specific Biomarkers by Integrating Genomics Analysis of DNA Copy Number Aberrations and miRNA-mRNA Dual Expression Profiling. BioMed Research International. 2015,2015:1-17.SCI
16. Dongguo Li, Hong Xia,Zhen-ya Li, Lin Hua*，Lin Li*.Identification of Novel Breast Cancer Subtype-Specific Biomarkers by Integrating Genomics Analysis of DNA Copy Number Aberrations and miRNA-mRNA Dual Expression Profiling. Journal of Biomedicine and Biotechnology. 2015,2015:1-17.SCI
17. Lin Hua1#,*, Hong Xia#,Ping Zhou, Li An*.Apply Support Vector Regression to Extract the Potential Susceptibility Genes of ChronicObstructive Pulmonary Disease . The 2014 7th International Conference on BioMedical Engineering and Informatics. 2014,BMEI2014:705-709.EI
18. Lin Hua#,*, Hong Xia#, Ping Zhou, Li An*.Explore the Associated MiRNAs with Emphysema Severity of Chronic Obstructive Pulmonary Disease. 2014 2nd International Conference on Systems and Informatics. 2014,ICSAI 2014:1057-1059.EI
19. Lin Hua#,*, Hong Xia#, Ping Zhou, Li An*.Targets of MiRNAs in Lung Cancer Related Pathways as Predictors of Chronic Obstructive Pulmonary Disease. 2014 2nd International Conference on Systems and Informatics. 2014,ICSAI 2014:1066-1070.EI
20. Lin Hua*, Hong Xia, Ping Zhou.Applying the complexity of networks to mine disease risk genes. Applied Mechanics and Materials. 2014,556-562 (2014):5958-5963.EI
21. Lin Hua#,*, Hong Xia#,Ping Zhou, Dongguo Li,Lin Li.Combination of microRNA expression profiling with genome-wide SNP genotyping to construct a coronary artery disease-related miRNA-miRNA synergistic network. BioScience Trends. 2014,8(6):297-307.SCI
22. Lin Hua*, Ping Zhou.Combining Protein–Protein Interactions Information with Support Vector Machine to Identify Chronic ObstructivePulmonary Disease Related Genes . Molecular Biology. 2014,48（2）:333-343.SCI
23. Lin Hua*, Lin Li*,Ping Zhou.Identifying Breast Cancer Subtype Related miRNAs from Two Constructed miRNAs Interaction Networks in Silico Method. Journal of Biomedicine and Biotechnology. 2013,Volume 2013, Article ID 798912:1-13.SCI
24. Lin Hua*, Zheng Yang，Hong Liu.Applying bioinformatics methods to detect the relationship among complex diseases. 2013 International Conference on Computational and Information Sciences. 2013,ICCIS 2013:214-217.EI
25. Lin Hua*, Lin Li, Ping Zhou, Zheng Yang.COMBINING GEOGRAPHIC REGION WITH META-ANALYSIS TO MAP THE POTENTIAL ASSOCIATION BETWEEN THREE GENETIC POLYMORPHISMS AND CORONARY ARTERY DISEASE. J MED BIOCHEM. 2013,32:1-19.SCI
26. Lin Hua*, Zheng Yang, Ping Zhou，Li An*.Using Comparative Genomic Hybridization Arrays (aCGH) Techniques to Detect Chronic Obstructive Pulmonary Disease Related Susceptibility Regions. International Journal of Bio-Science and Bio-Technology. 2013,5（2）:121-130.EI
27. Lin Hua*,#, Ping Zhou#, Lin Li*, Hong Liu, Zheng Yang.Prioritizing breast cancer subtype related miRNAs using miRNA–mRNA dysregulated relationships extracted from their dual expression profiling. Journal of Theoretical Biology. 2013,331:1-11.SCI
28. Lin Hua*,#, Li An#, Lin Li, Yong biao Zhang, Chen Wang.A bioinformatics strategy for detecting the complexity of Chronic Obstructive Pulmonary Disease in Northern Chinese Han Population. GENES GENET SYST. 2012,87:197-209.SCI
29. Lin Hua*, Zheng Yang, Hong Liu.Explore coronary artery disease related microRNA clusters by combing single nucleotide polymorphisms with microRNA microarray. 2012 5th International Conference on BioMedical Engineering and Informatics. 2012,BMEI 2012:1169-1173.EI
30. Lin Hua, Zheng Yang, Hong Liu*.A comparison between gene-gene sub networks associated with complex diseases and genetic loci-sets. 2011 4th International Conference on Biomedical Engineering and Informatics. 2011,BMEI 2011:1569-1573.EI
31. Lin Hua, Yongbin Liu, Dongguo Li*.Explore the domain features of co-regulation proteins, co-interaction proteins and co-regulation & cointeraction proteins. 2011 4th International Conference on Biomedical Engineering and Informatics. 2011,BMEI 2011:1587-1591.EI
32. Lin Hua*,#, Ping Zhou*,#, Hong Liu,Lin Li*, Zheng Yang,Zhi-chengLiu.Mining susceptibility gene modules and disease risk genes from SNP data by combining network topological properties with support vector regression . Journal of Theoretical Biology. 2011,289:225-236.SCI
33. Lin Hua#, Dong-guo Li#，Hui Lin, Lin Li, Xia Li*, Zhi-cheng Liu*.The Correlation of Gene Expression and Co-Regulated Gene Patterns in Characteristin KEGG Pathways. Journal of Theoretical Biology. 2010,266:242-249.SCI
主编或副主编的著作/译著
1. 《医用生物信息学理论与实践》,副主编,科学出版社,201905
2. 《医学生物信息学案例与实践》,主编,清华大学出版社,201801
3. 《医学数据挖掘案例与实践》,主编,清华大学出版社,201609
4. 《医学统计方法及SPSS实现》,副主编,科学出版社,201608
重要奖项