姓名：陈彪 性别：男 职称：教授 招生院所：附属宣武医院 招生类型：科学与专业学位(博) 科学与专业学位(硕) 招生专业：老年医学(博) 老年医学(硕) 研究方向名称：老年疾病的基础与临床 电子信箱：pbchan@hotmail.com


社会任职
1. 首都医科大学教授，博士生导师
2. 宣武医院神经内科副主任
3. 国家人类基因组北方研究中心副主任
4. 北京市老年保健及疾病防治中心副主任
5. 中国老年医学学会副会长
6. 国际老年学会和老年医学学会理事
7. 国家老年疾病临床医学研究中心主任
8. 中国老年学和老年医学学会副会长
个人简历
1. 197809-198308:湖南医学院医疗系 本科学习
2. 198509-199006:中山医科大学 神经病学博士研究生
3. 199008-199209:美国帕金森病研究所 博士后
4. 199206-199406:美国帕金森病研究所 研究员
5. 199404-199607:中山医科大学 客座副教授
6. 199407-200011:美国帕金森病研究所 高级研究员，课题主持人
7. 199502-200011:美国帕金森病研究所 分子遗传实验室主任
8. 199607-:中山医科大学 客座教授
9. 199810-:首都医科大学宣武医院 主任医师，教授
重要学术论文
1. Xu X, Chen J, Chen M, Gu Z, Ji S, Liu S, Chan P*.Postural Tremor Is Associated with Gait and Balance Impairments in Community-Dwelling Older People. J Am Geriatr Soc. 2019,67(4):799-803.SCI
2. Mi TM, Garg S, Ba F, Liu AP, Wu T, Gao LL, Dan XJ, Chan P*, McKeown MJ.High-frequency rTMS over the supplementary motor area improves freezing of gait in Parkinson's disease: a randomized controlled trial.. Parkinsonism Relat Disord. 2019,68:85-90.SCI
3. Yue F, Zeng S, Tang R, Tao G, Chan P*.MPTP Induces Systemic Parkinsonism in Middle-Aged Cynomolgus Monkeys: Clinical Evolution and Outcomes. Neurosci Bull. 2017,33(1):17-27.SCI
4. Xiu S, Zheng Z, Guan S, Zhang J, Ma J, Chan P.Serum uric acid and impaired cognitive function in community-dwelling elderly in Beijing. Neurosci Lett. 2017,637:182-187.SCI
5. Chhetri JK, Zheng Z, Xu X, Ma C, Chan P*.The prevalence and incidence of frailty in Pre-diabetic and diabetic community-dwelling older population: results from Beijing longitudinal study of aging II (BLSA-II). BMC Geriatr. 2017,17(1):47.SCI
6. 曹明，陈彪*.吸烟与帕金森病嗅觉障碍. 中国现代神经疾病杂志. 2017,02:101-104.核心期刊
7. 陈彪*,梅珊珊.规范脑深部电刺激术术前评估已是当务之急. 中国现代神经疾病杂志. 2017,02:85-87.核心期刊
8. 刘疏影,陈彪*.帕金森病流行现状. 中国现代神经疾病杂志. 2016,02:98-101.核心期刊
9. Cao M, Gu ZQ, Li Y, Zhang H, Dan XJ, Cen SS, Li DW, Chan P*.Olfactory Dysfunction in Parkinson's Disease Patients with the LRRK2 G2385R Variant. Neurosci Bull. 2016,32(6):572-576.SCI
10. Dan X, Wang C, Zhang J, Gu Z, Zhou Y, Ma J, Chan P*.Association between common genetic risk variants and depression in Parkinson's disease: A dPD study in Chinese. Parkinsonism Relat Disord. 2016,33:122-126.SCI
11. Shi C#, Zheng Z#, Wang Q, Wang C, Zhang D, Zhang M, Chan P*, Wang X*. Exploring the Effects of Genetic Variants on Clinical Profiles of Parkinson's Disease Assessed by the Unified Parkinson's Disease Rating Scale and the Hoehn-Yahr Stage. PLoS One. 2016,11(6):e**.SCI
12. Zhang H, Gu Z, Sun L, Cao M, Li D, Ma J, Chan P*.Clinical Manifestation of Parkinson's Disease in Association with Rapid Eye Movement Sleep Behavior Disorder Onset. Eur Neurol. 2016,76(3-4):154-160.SCI
13. Zheng Z, Guan S, Ding H, Wang Z, Zhang J, Zhao J, Ma J, Chan P*. Prevalence and Incidence of Frailty in Community-Dwelling Older People: Beijing Longitudinal Study of Aging II. J Am Geriatr Soc. 2016,64(6):1281-1286.SCI
14. 陈彪,刘疏影,安静,顾朱勤.可移动病历系统在帕金森病中的应用及培训作用. 中国病案. 2016,01:34-36.核心期刊
15. 刘平,张宝和,连士杰,陈彪*.老年帕金森病患者血清同型半胱氨酸及血尿酸水平与认知功能障碍的相关性. 中国临床保健杂志. 2015,03:225-227.核心期刊
16. Wu T*, Hallett M, Chan P.Motor automaticity in Parkinson's disease. Neurobiol Dis. 2015,82:226-34.SCI
17. Dan X, King BR, Doyon J, Chan P*.Motor Sequence Learning and Consolidation in Unilateral De Novo Patients with Parkinson's Disease. PLoS One. 2015,10(7):e**.SCI
18. Wu T*, Hou Y, Hallett M, Zhang J, Chan P.Lateralization of brain activity pattern during unilateral movement in Parkinson's disease. Hum Brain Mapp. 2015,36(5):1878-91.SCI
19. Xu S, Chan P*.Interaction between Neuromelanin and Alpha-Synuclein in Parkinson's Disease. Biomolecules. 2015,5(2):1122-42.SCI
20. Wang C, Xu Y, Feng X, Ma J, Xie S, Zhang Y, Tang BS, Chan P*. Linkage analysis and whole-exome sequencing exclude extra mutations responsible for the parkinsonian phenotype of spinocerebellar ataxia-2. Neurobiol Aging. 2015,36(1):545.e1-7.SCI
21. Wu T*, Liu J, Zhang H, Hallett M, Zheng Z, Chan P.Attention to Automatic Movements in Parkinson's Disease: Modified Automatic Mode in the Striatum. Cereb Cortex. 2015,25(10):3330-42.SCI
22. Li DW, Gu Z, Wang C, Ma J, Tang BS, Chen SD, Chan P*.Non-motor symptoms in Chinese Parkinson's disease patients with and without LRRK2 G2385R and R1628P variants. J Neural Transm . 2015,122(5):661-7.SCI
23. Wu T*, Ma Y, Zheng Z, Peng S, Wu X, Eidelberg D, Chan P.Parkinson's disease-related spatial covariance pattern identified with resting-state functional MRI. J Cereb Blood Flow Metab. 2015,35(11):1764-70.SCI
24. 王雪梅,冯涛,顾朱勤,刘萍,张璇,陈彪.帕金森病睡眠障碍与非运动症状的相关性研究. 中华老年心脑血管病杂志. 2015,05:507-510.核心期刊
25. Wu T, Chan P, Hallett M.Effective connectivity of neural networks in automatic movements in Parkinson’s disease. NeuroImage. 2010,49:2581-2587.SCI
26. Wu T, Wang L, Hallett M, Li K, Chan P.Neural correlates of bimanual anti-phase and in-phase movements in Parkinson's disease. Brain. 2010,133:2394-2409.SCI
27. Gu Z, Feng X, Dong X, Chan P.Smoking, genes encoding dopamine pathway and risk for Parkinson's disease. Neurosci Lett. 2010,482(1):31-34.SCI
28. Cai Y, Ding H, Li N, Chai Y, Zhang Y, Chan P.Oscillation development for neurotransmitter-related genes in the mouse striatum. Neuroreport. 2010,21 (2):79-83.SCI
29. Cai Y, Liu S, Sothern RB, Xu S, Chan P.Expression of clock genes Per1 and Bmal1 in total leukocytes in health and Parkinson’s disease. European Journal of Neurology. European Journal of Neurology. 2010,17:550-554.SCI
30. Wang C, Ma H, Feng X, Xie S, Chan P.Parkin dosage mutations in patients with early-onset sporadic and familial Parkinson's disease in Chinese: an independent pathogenic role. Brain Res. 2010,1358:30-38.SCI
31. Cai Y, Yuan Y, Lin Q, Chan P.Allele-specific-extension allows for base-pair neutral homozygotes to be discriminated by highresolution melting of small amplicons. Analytical Biochemistry. 2010,406(1):29-33.SCI
32. Cai Y, Yuan Y, Lin Q, Chan P.Allele-specific-extension allows for base-pair neutral homozygotes to be discriminated by highresolution melting of small amplicons. Analytical Biochemistry. 2010,406(1):29-33.SCI
33. Sun L, Xu S, Zhou M, Wang C, Wu Y, Chan P.Effects of cysteamine on MPTP-induced dopaminergic neurodegeneration in mice. Brain Res. 2010,1335:74-82.SCI
34. Wu T, Long X, Zang Y, Wang L, Hallett M, Li K, Chan P.Regional homogeneity changes in patients with Parkinson’s disease. Hum Brain Mapp. 2009,30(5):1502-1510.SCI
35. Qin Z, Zhang L, Sun F, Liu H, Fang X, Chan P.Chinese Parkinson Study Group. Depressive symptoms impacting on health-related quality of life in early Parkinson's disease: results from Chinese L-dopa exposed cohort. Clin Neurol Neurosurg. 2009,111(9):733-737.SCI
36. Fan W, Ding H, Ma J, Chan P.Impulse Control Disorders in Parkinson’s Disease in a Chinese Population. Neurosci Lett. 2009,465(1):6-9.SCI
37. Yang JF, Wu T, Li JY, Li YJ, Zhang YL, Chan P.DYT1 mutations in early onset primary torsion dystonia and Parkinson disease patients in Chinese populations. Neurosci Lett. 2009,450(2):117-121.SCI
38. 左晓虹，蔡彦宁，李宁，刘姝，张燕莉，陈彪.小鼠纹状体时钟基因表达的生后发育. 中华行为医学与脑科学杂志. 2009,18（5）:385-387.
39. 秦朝晖，陈彪，张丽燕，樊文辉，孙菲，方向华，孟琛，Caroline Tanner.早期帕金森病患者健康相关生活质量. 中华神经科杂志. 2009,42（8）:514-519.
40. 王坚，李尧华，郑晓立，张燕莉，李昕，于顺，何欣，陈彪.弱阳离子交换纳米磁珠介导的帕金森病血清蛋白质组学的初步研究. 中华神经科杂志. 2009,42（2）:98-101.
41. Zhang JL, Yang JF, Chan P.No Association between Polymorphism of Serotonin Transporter Gene and Depression in Parkinson’s disease in Chinese.. Neurosci Lett. 2009,455(3):155-158.SCI
42. Cai Y, Liu S, Sothern RB, Li N, Guan Y, Chan P.Epigenetic analysis of mPer1 promoter in peripheral tissues. Biological Rhythm Research. 2009,40(6):445-453.SCI
43. Cai Y, Liu S, Li N, Xu S, Zhang Y, Chan P.Postnatal ontogenesis of molecular clock in mouse striatum. Brain Res. 2009,1264:33-38.SCI
44. Liu N, Yue F, Tang WP, Chan P.An Objective Measurement of Locomotion Behavior for Hemiparkinsonian Cynomolgus Monkeys. J Neurosci Methods. 2009,183(2):188-194.SCI
45. Wu T, Wang L, Chen Y, Zhao C, Li K, Chan P.Changes of functional connectivity of the motor network in the resting state in Parkinson's disease. Neurosci Lett. 2009,460:6-10.SCI
46. 王莉莉，徐胜利，陈彪*.表没食子儿茶素没食子酸酯对6-OHDA导致的多巴胺能神经细胞损伤的保护作用. 中国行为医学科学. 2007,16:311-314.无
47. 郑晓立、陈彪*.美国神经病学学会公布的最新帕金森病循证医学指南. 中国现代神经疾病杂志. 2007,7(1):36－38.无
48. 王莉莉，陈彪*，徐胜利.EGCG对帕金森病神经保护作用的信号转导机制. 中国现代神经疾病杂志. 2007,7:14-17.无
49. 王莉莉，陈彪，徐胜利.6-羟多巴胺对SH-SY5Y细胞信号转导和转录激活因子1和3磷酸化水平的影响. 中华医学杂志. 2007,87:1048-1052.无
50. 何延波，陈彪*.α-synuclein基因多态性与帕金森病. 中华神经科杂志. 2007,40:133-135.无
51. Yu S, Li X, Liu GW, Han JY, Zhang CY, Li YH, Xu SL, Liu C, Gao YP, Yang H, Ueda K, Chan P*.Extensive nuclear localization of α-synuclein in normal rat brain neurons revealed by a novel monoclonal antibody. Neuroscience. 2007,145:539-555.SCI
52. Wu T, Zang Y, Wang L, Long X, Hallett M, Chen Y, Li K, Chan P*.Aging influence on functional connectivity of the motor network in the resting state. Neurosci Lett. 2007,422:164-8.SCI
53. Wu T, Zang Y, Wang L, Long X, Li K, Chan P*.Normal aging decreases regional homogeneity of the motor areas in the resting state. Neurosci Lett. 2007,423:189-193.SCI
54. 王雪梅，陈彪.组蛋白脱乙酰化酶在α-突触核蛋白抑制酪氨酸氧化酶表达中的作用. 首都医科大学学报. 2006,27(4):476-479.无
55. Xin Li, Yao-Hua Li, Jun-Yan Han, Shun Yu, Biao Chen.cDNA cloning, prokaryotic expression and purification of rat α-synuclein. Neuroscience Bulletin. 2006,22(1):29－33.无
56. 孙虹，陈彪，孙菲，张新卿，汤哲，刘宏军，方向华.合并静止性震颤的原发性震颤患者临床特点分析. 中国神经精神疾病杂志. 2006,32(4):314-317.无
57. 刘姝, 陈彪, 蔡彦宁, 温玫, 左晓虹.人外周血hPer1基因的节律表达的研究. 中国现代医学. 2006,16(3):381-383.无
58. 左晓虹，陈彪，蔡彦宁，吴燕川，刘姝，谢淑，温玫.MPTP对C57小鼠纹状体DA释放节律的影响. 首都医科大学学报. 2006,27(1):66-69.无
59. 曹三勇，徐胜利，陈彪.蛋白酶体抑制剂对神经细胞的双重作用. 脑与神经疾病杂志. 2006,14(4):274-298.无
60. 张晨，李昕，李尧华，韩俊燕，陈彪，于顺.细胞外α-突触核蛋白对MES23.5多巴胺能神经细胞的促增殖作用. 首都医科大学学报. 2006,27(5):616-619.无
61. Shengli Xu, Ming Zhou, Shun Yu, Yanning Cai , Alex Zhang, Kenji Ueda, Piu Chan.Oxidative stress induces nuclear translocation of c-terminus of α-synuclein in dopaminergic cells. Biochem Biophys Res Commun. 2006,342(1):330-5.SCI
62. Fuchun Lin, Chunshui Yu, Tianzi Jiang, Kuncheng Li, Chaozhe Zhu, Wanlin Zhu, Wen Qin, Yunyun Duan, Yun Xuan, Hong Sun, and Piu Chan.Discriminative analysis of relapsing neuromyelitis optica and relapsing-remitting multiple sclerosis based on two-dimensional histogram from diffusion tensor imaging. Neuroimage. 2006,31(2):543-9.SCI
63. 孙虹，陈彪，孙菲，张新卿，汤哲，刘宏军，吴晓光，方向华.北京地区中老年人群原发性震颤的流行病学研究. 中华神经科杂志. 2006,39 (3):189-192.无
64. 杨静芳，梁秀玲，马守忠，王丽娟，陈嵘，陈彪.74例肝豆状核变性患者中ATP7B基因七种新突变的发现. 中华神经科杂志. 2006,39(10):673-677.无
65. 陈新平，陈彪，马秋兰，汤哲，张丽梅，冯秀丽，董秀敏，杨静芳.中国北方老年人多巴胺受体D2基因多态性与吸烟的相关性研究. 现代预防医学. 2006,33(7):1057-1060.无
66. Feng Wang, Xiuli Feng, Jinhong Ma, Haiqiang Zou, Piu Chan.A common A340T variant in PINK1 gene associated with late-onset Parkinson’s disease in Chinese. Neurosci Lett. 2006,410(2):121－5.SCI
67. Yue Feng, Chen Biao, Wu Di, Dong Kai, Zeng Si-en, Zhang Yu.Biological Properties of neural progenitor cells isolated from the hippocampus of adult cynomolgus monkeys. Chin Med J. 2006,119(2):110-116.SCI
68. Chunlin Zou, Po Man Suen, Ying Zhang, Zeyu Wang, Piu Chan, Po Sing Leung, Y. Alex Zhang.Isolation and in vitro characterization of pancreatic progenitor cells from the islets of diabetic monkey models. Int J Biochem Cell Biol. 2006,38(5-6):973-84.SCI
69. 蔡彦宁，左晓虹，刘姝，谢淑，温玫，陈彪.利用荧光定量聚合酶链反应检测小鼠纹状体中Per1基因的表达规律. 首都医科大学学报. 2006,27(1):63-66.无
70. 温玫，蔡彦宁，田娜，刘桓，陈彪.成纤维细胞生长因子受体3 基因荧光定量聚合酶链反应检测方法的建立. 中华检验医学杂志. 2005,5（28-5）:499-500.无
71. Tao Wu, Piu Chan, Mark Hallett.Ageing influence on automatic movement. Physiology News. 2005,(59):30-31.无
72. 左晓虹，陈彪，蔡彦宁，刘姝.小鼠纹状体多巴胺水平的节律性变化. 中国临床康复. 2005,4（9-13）:28-36.无
73. 张新卿，陈彪，汤哲，刘宏军，李坤成，刘树良.轻度认知功能损害诊断：脑血管病因素对神经心理学指标的影响. 中国神经精神疾病杂志. 2005,31（5）:362-364.无
74. 李尧华，于顺，高亚萍，柳川，左晓虹，陈彪.揭示α-突触核蛋白与帕金森病的关系：α-突触核蛋白单克隆抗体的研究. 中国临床康复. 2005,1(9-7):44-46.无
75. 万华瑛，陈彪，杨静芳，董秀敏.烟酰胺嘌呤二核苷酸磷酸：醌氧化还原酶1基因多态性与认知功能减退和老年性痴呆的关系. 中国医学科学院学报. 2005,1（27-3）:285-288.无
76. Fa-GuoZhao,Yin-HuaWang,Jing-FangYang,Qiu-LanMa,ZheTang,Xiu-MinDong,Piu Chan.Association between acyl-coenzyme A: cholesterol acyltransterase gene and risk for Alzheimer’s disease in Chinese. Neuroscience Letters. 2005,(17-20):1-4.SCI
77. Shun Yu, Kenji Ueda, Piu Chan.α-Synuclein and Dopamine Metabolism. Molecular Neurobiology. 2005,31(1-3):243-254.SCI
78. 徐胜利，周明，刘平，张丽艳，徐艳玲，张愚，陈彪.6-羟多巴诱导大鼠黑质的持续胶质细胞反应. 神经解剖学杂志. 2005,3（21-2）:133-138.无
79. 徐胜利，周明，张丽燕，徐艳玲，陈彪.氧化应激诱导多巴胺能MES23.5细胞α-突触核蛋白C-末端片段核转位. 解剖学报. 2005,8（36-4）:337-341.无
80. 刘姝，蔡彦宁，冯秀丽，温玫，左晓虹，陈彪.改进竞争性RT-PCR法在定量PER1基因表达中的应用. 基础医学与临床. 2005,5（25-5）:309-413.无
81. 江小华，徐群渊，杨晖，陈彪.中国人群单胺氧化酶-B基因多态性与帕金森病相关性研究. 中华神经科杂志. 2005,37（3）:239-242.无
82. 周景升，张新卿，王丽冬，孟潮，楚长彪，陈彪.电话版常识-记忆-注意测验用于痴呆的信效度研究. 中国心理卫生杂志. 2004,18（9）:624-627.无
83. 杨静芳，江晓华，梁秀龄，王丽娟，陈嵘，李昕，陈彪.变性高效液相色谱在检测肝豆状核变性基因突变中的作用. 中国神经精神疾病杂志. 2004,30（2）:124-126.无
84. 邹海强，陈彪，马秋兰，李昕，杨静芳，冯秀丽，董秀敏，李勇杰.Parkin基因新的多态位点IVS3-21T-C增加早发性帕金森病的发病风险. 中华医学遗传学杂志. 2004,21（3）:106-110.无
85. 杜万良，王荫华，陈彪.PRKCG基因多态性扫描及其与帕金森病的相关性研究. 中国康复理论与实践. 2004,10(3):152-157.无
86. 刘平，刘焯霖，杨静芳，陈彪.早发性帕金森病与细胞色素P4501A1和N-乙酰基转移酶2基因多态性及个体易感危险性. 中国临床康复. 2004,8（4）:621-623.无
87. 于顺，刘雪梅，李尧华，吕国蔚，陈彪.重复急性低氧对小鼠大脑皮质中α-突触核蛋白表达的影响. 生理学报. 2004,56（2）:263-268.无
88. 黄越，杨静芳，齐晓涟，王育琴，王维治，陈彪.CYP2C19 和CYP2C9 基因型与苯妥英血药浓度关系的研究. 中华医学杂志. 2004,84(20):1686-1688.无
89. Shun Yu, Xiaohong Zuo, Yaohua Li, Chen Zhang, Ming Zhou, Yu Alex Zhang, Kenji Ueda, Piu Chan.Inhibition of tyrosine hydroxylase expression in α-synuclein-transfected dopaminergic neuronal cells. Neuroscience Letters. 2004,367(1):34-39.SCI
90. 江小华，杨慧，杨静芳，王海涛，徐群渊，陈彪.中国人NAD（P）H：醌氧化还原酶基因多态性与帕金森病遗传易感性的关系. 中华医学遗传学杂志. 2004,21（2）:120-123.无
91. 蔡彦宁，温玫，张愚，陈彪.帕金森病患者尾状核中基因表达谱的研究. 中华医学杂志. 2004,84（14）:1191-1193.无
92. 孟琛，汤哲，方向华，刘向红，吴晓光，刘宏军，刁丽君，陈彪.北京老年人认知功能对生存率影响的八年随访观察. 中华老年医学杂志. 2004,23（7）:507-509.无
93. 杨文明，陈彪，韩明向，鲍远程，张波，胡兵，刘爱萍.实验性阿尔茨海默病大鼠模型行为学、神经生化学病理学特征. 中国临床康复. 2004,8（19）:3737-3738.无
94. 于泓，李尧华，冯秀丽，吴燕川，周虹，陈彪.MES23.5 细胞酪氨酸羟化酶的种属来源及其重组酶的活性测定. 中国生物化学与分子生物学报. 2004,20 (1):95～100.无
95. 邹海强，陈彪，彭晓霞，冯秀丽，董秀敏.Parkin 基因S/ N167 多态性与帕金森病发病风险的Meta分析. 中国循证医学杂志. 2004,4(3):157-163.无
96. 蔡彦宁，温玫，左晓红，田娜，陈彪.阿尔茨海默病患者皮质额叶基因表达谱研究. 中国临床康复. 2004,8（28）:6068-6070.无
97. 关云谦，陈彪，邹春林，张愚.胚胎干细胞“五步法”体外诱导成为神经细胞的实验观察. 中国临床康复. 2004,8（10）:1851-1853.无
98. 邹海强，陈彪，冯秀丽，李昕，董秀敏.parkin 基因启动子区- 258T/ G多态性增加晚发帕金森病的发病风险. 中华神经科杂志. 2004,37(2):122-125.无
99. 傅求真，徐胜利，左晓红，徐燕玲，陈彪.1-甲基-4-苯基-吡啶盐致多巴胺能细胞系MES23.5死亡机制. 细胞生物学杂志. 2004,26（5）:539-543.无
100. 江小华，徐群渊，杨静芳，董秀敏，杨慧，陈彪.中国人单胺氧化酶A基因的EcoRV酶切位点多态性与帕金森病的相关性. 中国神经科学杂志. 2003,19(4):255-258.无
101. 江小华，杨慧，杨静芳，董秀敏，徐群渊，陈彪.单胺氧化酶A基因Fnu4H酶切位点多态性与帕金森病相关性研究. 中华医学遗传学杂志. 2003,20(3):211-214.无
102. Qiu-Lan Ma, Piu Chan, Mitsunobu Yoshii and Kenji Ueda.Alpha-Synuclein aggregation and neurodegenerative diseases: Is there a common pathogenesis?. Journal of Alzheimer’s Disease. 2003,5:139-148.无
103. 马秋兰，杨静芳，邵明，董秀敏，陈彪.阿尔茨海默病与NQ01和ApoE基因多态性关联分析. 中华医学杂志. 2003,83（24）:2124-2127.无
104. 王育琴，齐晓涟，黄越，陈彪.丙戊酸药物浓度与CYP2C19基因多态性关系的研究. 中国医院药学杂志. 2003,23(11):670-673.无
105. 刘雪梅，于顺，李尧华，周茗，左晓虹，吕国蔚，陈彪.抗人α-synuclein多克隆抗体的制备和鉴定. 首都医科大学学报. 2003,24（1）:7-10.无
106. Jian Wang, Zhuo-Lin Liu, Biao Chen.Association study of dopamine D2, D3 receptor gene polymorphisms with motor fluctuations in PD. NEUROLOGY. 2002,58(5):837-838.SCI
107. Y. X. Zheng, P. Chan, Z. F. Pan, N. N. Shi, Z. X. Wang, J. Pan, H. M. Liang, Y. Niu, X. R. Zhou and F. S. He.Polymorphism of metabolic genes and susceptibility to occupational chronic manganism. BIOMARKERS. 2002,7(4):337-346.SCI
108. Chan P,Meng C,Tanner C.Family history of Parkinson's disease: A multicenter case-control study in China. NEUROLOGY. 2002,58(7):A109-A109.SCI
109. Jie Wu, Piu Chan, Katherine M. Schroeder, Kevin Ellsworth and L. Donald L. Partridge.1-Methyl-4-phenylpridinium (MPP+)-induced functional run-down of GABA(A) receptor-mediated currents in acutely dissociated dopaminergic neurons. Journal of Neurochemistry . 2002,83(1):87-99.SCI
110. Jian Wang, Zhuo-Lin Liu, Biao Chen.Dopamine D5 receptor gene polymorphism and the risk of levodopa-induced motor fluctuations in patients with Parkinson's disease. Neurosci Lett . 2001,308(1):21-24.SCI
111. Matt Farrer, Piu Chan, Rong Chen, Louis Tan , Sarah Lincoln, Dena Hernandez, Lysia Forno, Katrina Gwinn-Hardy, Leonard Petrucelli, Jennifer Hussey, Andrew Singleton, Caroline Tanner, John Hardy, J. William Langston.Lewy bodies and parkinsonism in families with parkin mutations. Annals of Neurology. 2001,50(3):293-300.SCI
112. Jian Wang, Zhuolin Liu, Piu Chan.Lack of association between cytochrome P450 2E1 gene polymorphisms and Parkinson's disease in a Chinese population. Mov Disord. 2000,15(6):1267-1269.SCI
113. P. Chan, X. Jiang, L. S. Forno, D. A. Di Monte, C. M. Tanner, and J. W. Langston.Absence of mutations in the coding region of the alpha-synuclein gene in pathologically-proven Parkinson’s disease. Neurology. 1998, 50:1136-1137.SCI
114. Piu Chan, Caroline M. Tanner, Xin Jiang, and J. William Langston.Failure to find the alpha-synuclein gene missense mutation (G209A) in 100 patients with younger onset Parkinson’s disease. Neurology. 1998,50:513-514.SCI
115. Piu Chan, Donato A. Di Monte, J. William Langston and Ann Marie Janson.(+) MK-801 does not prevent MPTP-induced loss of nigral neurons in mice. J Pharmacol Exp Ther. 1997,280:439-4.SCI
116. P. Chan, C. W. Shults, C. M. Tanner, J. S. Fink, M. Kurth, K. L. Marek, L. W.Elmer and Parkinson Study Group.Use of a clinical trials population in genetic research. Am J Hum Genet. 1995,57(4suppl):A316.SCI
117. Piu Chan, Donato A. Di Monte, Jin-Jun Luo, Louis E. DeLanney, Ian Irwin, and J. William Langston.Rapid ATP loss cause by methamphetamine in the mouse striatum: relationship between energy impairment and dopaminergic neurotoxicity. J Neurochem. 1994,62:2484-2487.SCI
118. Piu Chan, Donato A. Di Monte, J. William Langston.Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine *(MPTP) on levels of glutamate and aspartate in the mouse brain. Brain Res. 1994,647:249-254.SCI
119. Piu Chan, J. William Langston, Ian Irwin, Louis E. DeLanney, and Donato A. Di Monte.2-Deoxyglucose enhances 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced ATP loss in the mouse brian. J Neurochem. 1993,61:610-616.SCI
120. Piu Chan, Yi Li, Zhong Zheng, Ping Hu, Sabine D. Sarbach and David Guez.Neurologic and histologic evaluation of almitrine +rabasine (Duxil) in middle cerebral artery occlusion in cats. Eur J Pharmacol. 1993,231:175-182.SCI
121. Chan P, Langston JW, Di Monte DA.MK-801 temporarily prevents MPTP-induced acute dopamine depletion and MPP+elimination in the mouse striatum. J Pharmacol Exp Ther. 1993,267:1515-1520.SCI
122. Donato A. Di Monte, Piu Chan, and Martha S. Sandy. Glutathione in Parkinson’s disease: a link between oxidative stress and mitochondrial damage?. Ann Neurol. 1992,32:S111-S115.SCI
123. Piu Chan, Louis E. DeLanney, Ian Irwin, J. William Langston, and Donato Di Monte.MPTP-induced ATP loss in mouse brain. Ann NY Acad Sci. 1992,648:306-308.SCI
124. Piu Chan, Louis E. DeLanney, Ian Irwin, J. William Langston, and Donato Di Monte.Rapid ATP depletion caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mouse brain. J Neurochem. 1991,57:348-351.SCI
125. C. M. Tanner, B. Chen, W. Wang, M. Peng, Z. Liu, X. Liang, L. C. Kao, D. W. Gilley, C. G. Goetz, and B. S. Schoenberg.Environmental factors and Parkinson’s disease: A case control study in China. Neurology. 1989,39:660-664.SCI
126. Caroline M. Tanner, B. Chen, J. A. Cohen, W. Wang and M. Peng, B. C. Summerville, Z. Liu and X. Liang, L. C. Kao and C. G. Goetz.Dietary antioxidant vitamines and the risk of developing Paikinson’s disease. Neurology. 1989,39(Suppl 1):229.SCI
127. Caroline M. Tanner, Biao Chen, Wen-Zhi Wang, David W. Gilley, Man-Ling Peng, Zho-Lin Liu and Xue-Ling Liang, Li Chiung Kao and Christopher G. Goetz, Bruce S.Environmental factors and Parkinson’s disease (PD): A case control study in China. Neurology. 1988,38(Suppl 1):349.SCI
主编或副主编的著作/译著
1.
重要奖项
1. 帕金森病及运动障碍疾病的分子诊断与功能影像研究 中华医学科技奖 二等奖 201612
2. 帕金森病的发病机制、预警和干预研究 北京市科学技术奖 一等奖 201512
3. 老年痴呆的流行病学研究 北京市科学技术奖 二等奖 2004
4. 帕金森病病因学研究 茅以升科学技术奖--北京青年科技奖 提名奖 2002
5. 帕金森病病因的分子遗传学研究 中华医学科技奖 一等奖 2002
6. 帕金森病遗传易感性的系列研究 广东省科技进步奖 二等奖 1998
7. 帕金森病的遗传和环境危险因素研究 教育部科技成果 三等奖 1990