姓名：李锋 性别：男 职称：主任医师、教授 招生院所：附属朝阳医院 招生类型：科学与专业学位(博) 科学与专业学位(硕) 招生专业：临床病理学(博) 临床病理学(硕) 研究方向名称：肿瘤病理与分子诊断 电子信箱：lifeng7855@126.com


社会任职
1. 中国医师协会病理科医师分会会员
2. 中华医学会病理学分会委员
3. 教育部高校基础医学专业教学指导委员会委员
4. 国家卫计委病理质控与评估中心专家委员会委员
5. 中华病理学杂志、临床与实验病理学杂志编委
6. 中国抗癌协会肿瘤病理专业委员会委员
7. 北京医学会病理分会常委
8. 中国研究型医院学会病理专业委员会常委
9. 中国医师协会科研出版工作委员会常委
个人简历
1. 198090-198506:石河子医学院 临床医学专业本科
2. 198507-201512:石河子大学医学院病理学系/第一附属医院病理科 教授/主任医师 主任
3. 198909-199008:华西医科大学病理科全国病理诊断医师进修班 学员
4. 199209-199506:上海医科大学肿瘤医院肿瘤(病理)学专业 硕士研究生
5. 200009-200401:复旦大学医学院肿瘤医院肿瘤（病理）学专业 博士研究生
6. 200804-200810:美国耶鲁大学医学院病理系分子诊断室 访问
7. 201312-201401:以色列西勒雅法医学中心病理科 访问教授
8. 201601-202004:首都医科大学附属北京朝阳医院科研处/医学研究中心/病理科 主任/副主任
重要学术论文
1. Yunzhao Chen#,Huahua Xin#,Hao Peng#,Qi Shi,Menglu Li,Jie Yu,Yanxia Tian,Xueping Han,Xi Chen,Yi Zheng,Jun Li,Zhihao Yang,Lan Yang,Jianming Hu,Xuan Huang,Zheng Liu,Xiaoxi Huang,Hong Zhou,Xiaobin Cui*,Feng Li*.Hypomethylation-linked activation of PLCE1 impedes autophagy via MDM2-mediated ubiquitination and destabilization of p53 and promotes tumorigenesis. Cancer Res. 2020,2020.2.17.Online.:doi:10.1158/0008-5472.CAN-19-1912 .SCI
2. Wang Yang#;Zhang Liang#;Pang Yuwen#;Song Lingxie;Shang Hao;Li Zhenzhen;Liu Qianqian; Zhang Yangyang;Wang Xiaomeng;Li Qianru;Zhang Qiaochu;Liu Chunxia*;Li Feng*.The MicroRNA-29 family inhibit rhabdomyosarcoma formation and progression by regulating GEFT function. Am J Transl Res. 2020,12(3):001-010 .SCI
3. Lianghai Wang#,Zhiyu Zhang#,Xiaodan Yu#,Xiaoxi Huang,Qian Wang,Xuepin Han,Yang guang Song,Aimin Chang,Jianming Hu,Lijuan Pang,Jun Hou*,Feng Li*. .SOX9/miR-203a Axis Drives PI3K/AKT Signaling to Promote Esophageal Cancer Progression. Cancer Lett. 2020,468:14-26.SCI
4. Qiaochu Zhang#,Pengpeng Zhang#,Bingcheng Li,Hongwei Dang,Jinfang Jiang,Lian Meng, Haijun Zhang,Yangyang Zhang,Xiaomeng Wang,Qianru Li,Yang wang,Chunxia Liu*,Feng Li*..The Expression of Perilipin Family Proteins Can Be UsedasDiagnosticMarkers of Liposarcoma andto Differentiate Subtypes. J Cancer. 2020,11(14):4081-4090.SCI
5. Yunzhao Chen#,Dandan Wang#,Hao Peng#,Xi Chen,Jie Yu,Lirong Liang,Zheng Liu,Yi Zheng, Jun Li,Hong Zhou,Xiaobin Cui*,Feng Li*..Epigenetically upregulated oncoprotein PLCE1 drives esophageal carcinoma angiogenesis and proliferation via activating the NF-κB signaling pathway and VEGF-C/Bcl-2 expression. Mol Cancer. 2019,18(1):1-19.SCI
6. Lianghai Wang#,Zhiyu Zhang#,Xiaodan Yu#,Xuan Huang,Zheng Liu,Yuhang Chai,Lei Yang, Qian Wang,Man Li,Jin Zhao,Jun Hou*,Feng Li*. Unbalanced YAP–SOX9 Circuit Drives Stemness and Malignant Progression in Esophageal Squamous Cell Carcinoma. Oncogene . 2019,38:2042–2055.SCI
7. Chunxia Liu*,Liang Zhang,Wenwen Cui,Juan Du,Zhenzhen Li,Yuwen Pang,Qianqian Liu,Hao Shang,Lian Meng,Wanyu Li,Lingxie Song,Ping Wang,Yuwen Xie,Yuanyuan Wang,Yang Liu, Jianming Hu,Wenjie Zhang,Feng Li*. .Epigenetically upregulated GEFT-derived invasion and metastasis of rhabdomyosarcoma via epithelial mesenchymal transition promoted by the Rac1/Cdc42-PAK signalling pathway. EBioMed. 2019,50:122-134 .SCI
8. Qianqian Liu,Zhenzhen Li,Hao Shang,Qiaochu Zhang,Xiaomeng Wang,Yangyang Zhang, YangWang,Qianru Li,Chunsen Li,Chunxia Liu*,Feng Li*. Scavenger Receptor Class B Type 1(SR-B1) being a Potential Biomarker for the Diagnosis of Liposarcoma and Associated with the Degree of Differentiation of Liposarcom. J Cancer. 2019,10(18):4326-4332.SCI
9. Hao Shang#,Yang Liu#,Zhenzhen Li,Qianqian Liu,Wenwen Cui,Liang Zhang,Yuwen Pang, Chunxia Liu*,Feng Li*.MicroRNA-874 functions as a tumor suppressor in rhabdomyosarcoma by directly targeting GEFT. Am J Cancer Res. 2019,9(4):668-681.SCI
10. Yuhang Chai#,Qihang Li#,Hongying Zhao#, Zhiyu Zhang,Xiaodan Yu,Lijuan Pang,Zheng Liu, Jin Zhao,Lianghai Wang*,Feng Li*. SOX2 Antagonizes WWC1 to Drive YAP1 Activation in Esophageal Squamous Cell Carcinoma. Cancer Med. 2019,8:7055-7064.SCI
11. Manli Liu#,Yan Qi#,Lili Zhao#,Dongdong Chen,Yang Zhou,Hongrun Zhou,Yanmin Lv,Lu Zhang, Shan Jin,Shugang Li,Hong Zou,Wei Jia,Cuicui Wang,Jinfang Jiang,Weihua Liang,Lijuan Pang*, Feng Li*.Matrix metalloproteinase-14 induces epithelial-to-mesenchymal transition in synovial sarcoma. Hum Pathol . 2018,80:201-209.SCI
12. Xiaobin Cui#,Xi Chen#,Weiwei Wang#,Aimin Chang,Chunxia Liu,Lan Yang,Yutao Wei,Weihua Liang,Lidong Wang,Yunzhao Chen,Feng Li*.Epigenetic silencing of miR-203 in Kazakh patients with esophageal squamous cell carcinoma by MassARRAY Spectrometry. Epigenetics. 2017,12(8):698-707 .SCI
13. Lianghai Wang#,Xiaodan Yu#,Zhiyu Zhang#,Li Juan Pang,Jiang Xu,Jingfang Jiang,WeiHua Liang,Yuhang Chai,Jun Hou*,Feng Li*.Linc-ROR Promotes Esophageal Squamous Cell Carcinoma Progression through the Derepression of SOX9. J Exp Clin Cancer Res . 2017,36:182:s13046-017-0658-2.SCI
14. JianMing Hu, AiMin Chang,YunZhao Chen,XiangLin Yuan,Feng Li*.Regulatory Role of miR-203 in Occurrence and Progression of Kazakh Esophageal squamous cell carcinoma. Sci Rep. 2016,6:23780:srep23780.SCI
15. Wei Jia,Yuling Dong,Lin Tao,Lijuan Pang,Yan Ren,Weihua Liang,Jinfang Jiang,Gang Cheng, Wenjie Zhang,Xianglin Yuan,Feng Li*.MAP3K3 overexpression is associated with poor survival in ovarian carcinoma. . Hum Pathol. . 2016,50::162-169.SCI
16. Chengfang Li,Yaoyuan Shen,Yan Ren, Wei Liu, Man Li,Weihua Liang,Chunxia Liu*,Feng Li*.Oncogene mutation profiling reveals poor prognosis associated with FGFR1/3 mutation in liposarcoma. Hum Pathol. . 2016, 55::143-150.SCI
17. Xiaobin Cui#, Shumao Zhang#,Yuexun Xu,Hongwei Dang,Chunxia Liu,Lianghai Wang,Lan Yang, Jianming Hu,Weihua Liang, Jinfang Jiang,Na Li,Yong Li*,Yunzhao Chen*,Feng Li*.PFN2, a novel marker of unfavorable prognosis, is a potential therapeutic target involved in esophageal squamous cell carcinoma. J Transl Med.. 2016,14:137:s12967-016-0884-y.SCI
18. Yuwen Cao,Yixiao Li, Na Zhang, Jianming Hu, Liang Yin, Zemin Pan,Yucong Li,Xiaoming Du, Wenjie Zhang,Feng Li*.Quantitative DNA hypomethylation of ligand Jagged1 and receptor Notch1 signifies occurrence and progression of breast carcinoma. Am J Cancer Res. 2015,5 (5)::1621-1634.SCI
19. Qi Yan,Wang Ning,Zou Hong,Pang Li-Juan,Zhao Jin,Hu Jian-Ming,Zhang Jun,Liu Chun-Xia, Zhang Wen-Jie,Yuan Xiang-Lin andLi Feng*.Identification of potential mutations and genomic alterations in the epithelial and spindle cells components of biphasic synovial sarcomas using a human exome SNP chip. BMC Med Genomics. . 2015,8: :69.SCI
20. Yuan Ren,Kunpeng Liu,Xueling Kang,Lijuan Pang,Yan Qi,Zhenyan Hu,Wei Jia,Jin Zhao, Hai jun Zhang,Jianming Hu,Li Li,Weihua Liang,Hong Zou*,Xianglin Yuan,Feng Li*.Chromophobe renal cell carcinoma with and without sarcomatoid change: a clinicopathological, comparative genomic hybridization,and whole-exome sequencing study. Am J Translational Res. . 2015,7(11): :2482–2499.SCI
21. Ningjing Zou#,Lan Yang#,Ling Chen#,Tingting Li,Tingting Jin,Hao Peng,Shumao Zhang, Dan dan Wang,Ranran Li,Chunxia Liu,Jinfang Jiang,Lianghai Wang,Weihua Liang,Jianming Hu, Shu gang Li,Chuanyue Wu,Xiaobin Cui*,Yunzhao Chen*,Feng Li*.Heterozygote of TAP1 Codon 637 decreases susceptibility to HPV infection but increases susceptibility to esophageal cancer among the Kazakh populations. J Exp Clin Cancer Res. 2015,34:70 :s13046- 015-0185-y.SCI
22. Xiaobin Cui,Yaoyuan Shen,Tingting Li,Su Li,Shumao Zhang,Hao Peng,Jianming Hu,Chunxia Liu,Lan Yang,Jing Jin,Jinfang Jiang,Weihua Liang,Na Li,Zhenzhu Sun,Shugang Li,Chuanyue Wu,Yunzhao Chen and Feng Li*.SLC39A6: a potential target for diagnosis and therapy of esophageal carcinoma.. J Transl Med. 2015,13:321:s12967-015-0681-z.SCI
主编或副主编的著作/译著
1. 《2015-2016年新疆地区肿瘤登记报告》,主编,人民卫生出版社,201902
2. 《2014年新疆地区肿瘤登记报告》,主编,人民卫生出版社,201609
重要奖项
1. 新疆地区食管鳞癌早诊及预后相关分子的评价与应用研究（**R01） 其他省级科技奖 三等奖 201812
2. 新疆民族高发性HPV相关肿瘤的防治基础与临床应用研究（） 其他省级科技奖 一等奖 201512
3. 肾细胞癌的临床病理学与分子分型应用研究（） 其他省级科技奖 二等奖 201312
4. 软组织肉瘤特异性融合基因的分子诊断学研究（**） 其他省级科技奖 一等奖 200410