姓名：金子兵 性别：男 职称：教授 招生院所：附属同仁医院 招生类型：科学与专业学位(博) 科学与专业学位(硕) 招生专业：眼科学(博) 眼科学(硕) 研究方向名称：眼科遗传与再生 电子信箱：jinzibing@foxmail.com


社会任职
1. 中华医学会眼科学分会学组委员
2. 中国眼科遗传联盟常务理事
3. 中国医师协会眼科分会遗传学组副组长
4. 中国医师协会眼科分会青年委员会委员
5. 眼科与视觉科学研究协会(ARVO) 遗传交叉学组(GEN) 组长(chair)
6. 中国妇幼眼保健专委会儿童眼肿瘤与遗传学组副组长
7. 《Experimental Eye Research》编委
8. 《Ophthalmic Research》Associate editor
9. 《Ophthalmic Genetics》编委
10. 《中华干细胞与细胞杂志》编委
11. 《中华眼视光学与视觉科学杂志》编委
12. 《Frontiers in Cell and Developmental Biology》Review editor
13. 海峡医学会眼科分会眼干细胞学组副组长
个人简历
1. 199509-200007:温州医学院眼视光学系 医学本科学习
2. 200008-200304:温州医学院附属眼视光医院 住院医师/助教
3. 200304-200703:日本宫崎大学医学部眼科 博士生
4. 200704-200903:日本理化学研究所(RIKEN) JSPS外籍特别研究员（博士后）
5. 200904-201012:日本理化学研究所(RIKEN) FPR研究员(Research Scientist)
6. 201101-202002:温州医科大学附属眼视光医院（眼视光学与视觉科学国家重点实验室） 遗传眼病专科主任、干细胞研究所所长、视网膜再生医疗研究组PI、教授、博导
7. 202002-:首都医科大学附属北京同仁医院 教授
重要学术论文
1. 夏璐琦，蔡雪碧，郑逸晗，文昕然，周方越，直井信久，金子兵*.小口病致病基因诊断. 中华眼底病杂志. 2020,36(3):192-195.核心期刊
2. Zhang CJ, Xiang L, Wang XY, Chen XJ, Wu KC, Zhang BW, Chen DF, Jin GH, Chen YC, Liu WQ, Zhang H, Li ML, Ma Y, Jin ZB*.Ablation of mature miR-183 leads to retinal dysfunction in mice. Invest Ophthalmol Vis Sci. 2020,61(3):12.SCI
3. 沈人娟，周容，冯卓堃，王小芳，陈冲，陈珍姬，金子兵*.青少年型神经元蜡样脂褐质沉积症的基因诊断. 中华实验眼科杂志. 2020,38(1):45-49.核心期刊
4. Cai XB, Zheng YH, Chen DF, Zhou FY, Xia LQ, Wen XR, Yuan YM, Han F, Piao SY, Zhuang W, Lu F, Qu J*, Yu AY*, Jin ZB*.Expanding the Phenotypic and Genotypic Landscape of Nonsyndromic High Myopia: A Cross-Sectional Study in 731 Chinese Patients. Invest Ophthalmol Vis Sci. 2019,60:4052-4062.SCI
5. Lin R, Shen M, Pan D, Xu SZ, Shen RJ, Shao Y, Shi C, Lu F*, Jin ZB*.Relationship Between Cone Loss and Microvasculature Change in Retinitis Pigmentosa. Invest Ophthalmol Vis Sci. 2019,60(14):4520-4531.SCI
6. Jin ZB*, Gao ML, Deng WL, Wu KC, Sugita S, Mandai M, Takahashi M.Stemming retinal regeneration with pluripotent stem cells. Progress in Retinal and Eye Research. 2019,69:38-56.SCI
7. Wu KC, Chen XJ, Jin GH, Wang XY, Yang DD, Li YP, Xiang L, Zhang BW, Zhou GH, Zhang CJ, Jin ZB*.Deletion of miR-182 leads to retinal dysfunction in mice. Invest Ophthalmol Vis Sci. 2019,60(4):1265-1274.SCI
8. Huang XF#, Xiang L#, Fang XL, Liu WQ, Zhuang YY, Chen ZJ, Shen RJ, Cheng W, Han RY, Zheng SS, Chen XJ, Liu X, Jin ZB*.Functional characterization of CEP250 variant identified in non-syndromic retinitis pigmentosa. Human Mutation. 2019,40:1039-1045.SCI
9. Cai XB#, Wu KC#, Zhang X#, Lv JN, Jin GH, Xiang L, Chen J, Huang XF, Pan D, Lu B, Lu F, Qu J, Jin ZB*.Whole exome sequencing identified ARL2 as a novel candidate gene for MRCS (microcornea, rod-cone dystrophy, cataract, and posterior staphyloma) syndrome. Clinical Genetics. 2019,96:61-71. Cover story.SCI
10. Jin ZB, Li Z, Liu Z, Jiang Y, Cai XB, Wu J*.Identification of de novo germline mutations and causal genes for sporadic diseases using trio-based whole-exome/genome sequencing. Biological Reviews. 2018,93:1014-31.SCI
11. 杨极#, 王青锋#, 林蒙, 何凯文, 雷新兰, 高美玲, 潘登* and 金子兵*.视网膜感光细胞对仿生电场刺激的非矢量应答. 中国科学-生命科学. 2018,5:544-555.核心期刊
12. Deng WL#, Gao ML#, Lei XL, Lv JN, Zhao H, He KW, Xia XX, Li LY, Chen YC, Li YP, Pan D, Xue T, Jin ZB*.Gene Correction Reverses Ciliopathy and Photoreceptor Loss in iPSC-Derived Retinal Organoids from Retinitis Pigmentosa Patients. Stem Cell Reports. 2018,10:1267-1281. BEST OF 2018-2019.SCI
13. Huang XF#, Xiang L#, Cheng W, Cheng FF, He KW, Zhang BW, Zheng SS, Han RY, Zheng YH, Xu XT, Yu HY, Zhuang W, Leung YF, Jin ZB*.Mutation of IPO13 causes recessive ocular coloboma, microphthalmia, and cataract. Experimental and Molecular Medicine. 2018,50:53. Hightlight.SCI
14. Yang J*#, Jin ZB*#, Chen J, Huang XF, Li XM, Liang YB, Mao JY, Chen X, Zheng Z, Bakshi A, Zheng DD, Zheng MQ, Wray NR, Visscher PM, Lu F*, Qu J*.Genetic signatures of high-altitude adaptation in Tibetans. Proc Natl Acad Sci U S A. 2017,114:4189-94. Highlight.SCI
15. Jin ZB*#, Wu J#, Huang XF, Feng CY, Cai XB, Mao JY, Xiang L, Wu KC, Xiao X, Kloss BA, Li Z, Liu Z, Huang S, Shen M, Cheng FF, Cheng XW, Zheng ZL, Chen X, Zhuang W, Zhang Q, Young TL, Xie T, Lu F*, Qu J*.Trio-based exome sequencing arrests de novo mutations in early-onset high myopia. Proc Natl Acad Sci U S A. 2017,114:4219-24.SCI
16. Xiang L#, Chen XJ#, Wu KC, Zhang CJ, Zhou GH, Lv JN, Sun LF, Cheng FF, Cai XB, Jin ZB*.miR-183/96 plays a pivotal regulatory role in mouse photoreceptor maturation and maintenance. Proc Natl Acad Sci U S A. 2017,114:6376-81.SCI
17. Gao ML, Wu KC, Deng WL, Lei XL, Xiang L, Zhou GH, Feng CY, Cheng XW, Zhang CJ, Gu F, Wu RH*, Jin ZB*.Toll-Like Receptor 3 Activation Initiates Photoreceptor Cell Death In Vivo and In Vitro. Invest Ophthalmol Vis Sci. 2017,58:801-811.SCI
18. Rao FQ, Cai XB, Cheng FF, Cheng W, Fang XL, Li N, Huang XF, Li LH, Jin ZB*.Mutations in LRP5, FZD4, TSPAN12, NDP, ZNF408 or KIF11 genes account for 38.7% Chinese patients with familial exudative vitreoretinopathy. Invest Ophthalmol Vis Sci. 2017,58(5):2623-2629.SCI
19. Huang XF, Mao JY, Huang ZQ, Rao FQ, Cheng FF, Li FF, Wang QF, Jin ZB*.Genome-Wide Detection of Copy Number Variations in Unsolved Inherited Retinal Disease. Invest Ophthalmol Vis Sci. 2017,58:424-429.SCI
20. Huang XF, Huang F, Wu KC, Wu J, Chen J, Pang CP, Lu F, Qu J, and Jin ZB*.Genotype-phenotype correlation and mutation spectrum in a large cohort of inherited retinal dystrophy patients revealed by next-generation sequencing. Genetics in Medicine. 2015,7:271-278.SCI
21. Huang X, Wu J, Lv J, Zhang X, Jin ZB*.Identification of false-negative mutations missed by next-generation sequencing in retinitis pigmentosa patients: a complementary approach to clinical genetic diagnostic testing. Genetics in Medicine. 2015,17:307-311.SCI
22. Xiang P, Wu KC, Zhu Y, Xiang L, Li C, Chen DL, Chen F, Xu G, Wang A, Li M*, Jin ZB*.A novel Bruch's membrane-mimetic electrospun substrate scaffold for human retinal pigment epithelium cells. Biomaterials. 2014,35:9777-9788.SCI
23. 金子兵*.新一代基因测序技术有力推动分子眼科学发展. 中华眼视光学与视觉科学杂志. 2014,18(1):5-7.核心期刊
24. 邓雯丽 ，向萍, 金子兵*.多能干细胞分化来源视网膜色素上皮细胞移植治疗视网膜变性研究进展. 中华细胞与干细胞杂志. 2014,2:97-103.核心期刊
25. Jin ZB, Huang XF, Lv JN, Xiang L, Li DQ, Chen JF, Huang CJ, Wu J, Lu F, Qu J*.SLC7A14 linked to autosomal recessive retinitis pigmentosa. Nature Communications. 2014,5:3517.SCI
26. Jin ZB*, Okamoto S, Xiang P, Takahashi M.Integration-free iPS cells derived from retinitis pigmentosa patient for disease modeling. Stem Cells Translational Medicine. 2012,1:503-509. Cover story.SCI
主编或副主编的著作/译著
1. 《眼科学》,主编,中国医药科技出版社,201609
2. 《儿童眼保健与公共卫生》,副主编,高等教育出版社,201412
重要奖项
1. 视网膜色素变性的分子机理和干细胞研究 省自然科学奖一等奖 省部级 201804
2. 重大出生缺陷性眼病的新致病基因发现及机理研究 教育部自然科学奖二等奖 省部级 201609